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Items: 20

1.

Grants4Targets: an open innovation initiative to foster drug discovery collaborations.

Dorsch H, Jurock AE, Schoepe S, Lessl M, Asadullah K.

Nat Rev Drug Discov. 2015 Jan;14(1):74-6. doi: 10.1038/nrd3078-c2. Epub 2014 Nov 28. No abstract available.

PMID:
25430867
2.

"Collaborative innovation"--regaining the edge in drug discovery.

Wild H, Huwe C, Lessl M.

Angew Chem Int Ed Engl. 2013 Mar 4;52(10):2684-7. doi: 10.1002/anie.201208734. Epub 2013 Jan 17. No abstract available.

PMID:
23335097
3.

Promoting drug discovery by collaborative innovation: a novel risk- and reward-sharing partnership between the German Cancer Research Center and Bayer HealthCare.

Wellenreuther R, Keppler D, Mumberg D, Ziegelbauer K, Lessl M.

Drug Discov Today. 2012 Nov;17(21-22):1242-8. doi: 10.1016/j.drudis.2012.04.004. Epub 2012 Apr 12. Review.

PMID:
22521665
4.

Crowd sourcing in drug discovery.

Lessl M, Bryans JS, Richards D, Asadullah K.

Nat Rev Drug Discov. 2011 Apr;10(4):241-2. doi: 10.1038/nrd3412. No abstract available.

PMID:
21455221
5.

Grants4Targets - an innovative approach to translate ideas from basic research into novel drugs.

Lessl M, Schoepe S, Sommer A, Schneider M, Asadullah K.

Drug Discov Today. 2011 Apr;16(7-8):288-92. doi: 10.1016/j.drudis.2010.11.013. Epub 2010 Dec 1. Review.

PMID:
21129498
6.

AKR1B7 (mouse vas deferens protein) is dispensable for mouse development and reproductive success.

Baumann C, Davies B, Peters M, Kaufmann-Reiche U, Lessl M, Theuring F.

Reproduction. 2007 Jul;134(1):97-109.

PMID:
17641092
7.
8.

Activation of meiotic maturation in rat oocytes after treatment with follicular fluid meiosis-activating sterol in vitro and ex vivo.

Hegele-Hartung C, Grützner M, Lessl M, Grøndahl C, Ottesen J, Brännström M.

Biol Reprod. 2001 Feb;64(2):418-24.

PMID:
11159342
9.

Luteinizing hormone induces mouse vas deferens protein expression in the murine ovary.

Brockstedt E, Peters-Kottig M, Badock V, Hegele-Hartung C, Lessl M.

Endocrinology. 2000 Jul;141(7):2574-81.

PMID:
10875260
10.

Meiosis-activating sterol-mediated resumption of meiosis in mouse oocytes in vitro is influenced by protein synthesis inhibition and cholera toxin.

Grøndahl C, Lessl M, Faerge I, Hegele-Hartung C, Wassermann K, Ottesen JL.

Biol Reprod. 2000 Mar;62(3):775-80.

PMID:
10684823
11.

Nuclear and cytoplasmic maturation of mouse oocytes after treatment with synthetic meiosis-activating sterol in vitro.

Hegele-Hartung C, Kuhnke J, Lessl M, Grøndahl C, Ottesen J, Beier HM, Eisner S, Eichenlaub-Ritter U.

Biol Reprod. 1999 Nov;61(5):1362-72.

PMID:
10529286
12.

Meiosis-activating sterol promotes resumption of meiosis in mouse oocytes cultured in vitro in contrast to related oxysterols.

Grøndahl C, Ottesen JL, Lessl M, Faarup P, Murray A, Grønvald FC, Hegele-Hartung C, Ahnfelt-Rønne I.

Biol Reprod. 1998 May;58(5):1297-302.

PMID:
9603267
13.

Comparative messenger ribonucleic acid analysis of immediate early genes and sex steroid receptors in human leiomyoma and healthy myometrium.

Lessl M, Klotzbuecher M, Schoen S, Reles A, Stöckemann K, Fuhrmann U.

J Clin Endocrinol Metab. 1997 Aug;82(8):2596-600.

PMID:
9253340
14.

Common mechanisms in bacterial conjugation and Ti-mediated T-DNA transfer to plant cells.

Lessl M, Lanka E.

Cell. 1994 May 6;77(3):321-4. Review. No abstract available.

PMID:
8181052
15.
16.

Relationship of DNA-transfer-systems: essential transfer factors of plasmids RP4, Ti and F share common sequences.

Lessl M, Pansegrau W, Lanka E.

Nucleic Acids Res. 1992 Nov 25;20(22):6099-100. No abstract available.

17.
19.

Dissection of IncP conjugative plasmid transfer: definition of the transfer region Tra2 by mobilization of the Tra1 region in trans.

Lessl M, Balzer D, Lurz R, Waters VL, Guiney DG, Lanka E.

J Bacteriol. 1992 Apr;174(8):2493-500.

20.

Identification and characterization of two entry exclusion genes of the promiscuous IncP plasmid R18.

Lessl M, Krishnapillai V, Schilf W.

Mol Gen Genet. 1991 May;227(1):120-6.

PMID:
1904533

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