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Items: 1 to 50 of 124

1.

Effect of β-Lactam Plus Macrolide Versus Fluoroquinolone on 30-Day Readmissions for Community-Acquired Pneumonia.

Gilbert TT, Arfstrom RJ, Mihalovic SW, Dababneh AS, Varatharaj Palraj BR, Dierkhising RA, Mara KC, Lessard SR.

Am J Ther. 2018 May 22. doi: 10.1097/MJT.0000000000000788. [Epub ahead of print]

PMID:
30418221
2.

Sucrose nonfermenting AMPK-related kinase (SNARK) regulates exercise-stimulated and ischemia-stimulated glucose transport in the heart.

Sun XL, Lessard SJ, An D, Koh HJ, Esumi H, Hirshman MF, Goodyear LJ.

J Cell Biochem. 2018 Sep 7. doi: 10.1002/jcb.27425. [Epub ahead of print]

PMID:
30256437
3.

50 Gb/s short-reach interconnects with DSP-free direct-detection enabled by CAPS codes.

Morsy-Osman M, Fresi F, Forestieri E, Secondini M, Potì L, Cavaliere F, Lessard S, Plant DV.

Opt Express. 2018 Jul 9;26(14):17916-17926. doi: 10.1364/OE.26.017916.

PMID:
30114074
4.

JNK regulates muscle remodeling via myostatin/SMAD inhibition.

Lessard SJ, MacDonald TL, Pathak P, Han MS, Coffey VG, Edge J, Rivas DA, Hirshman MF, Davis RJ, Goodyear LJ.

Nat Commun. 2018 Aug 2;9(1):3030. doi: 10.1038/s41467-018-05439-3.

5.

A Numerical Preoperative Planning Model to Predict Arterial Deformations in Endovascular Aortic Aneurysm Repair.

Mohammadi H, Lessard S, Therasse E, Mongrain R, Soulez G.

Ann Biomed Eng. 2018 Jul 11. doi: 10.1007/s10439-018-2093-8. [Epub ahead of print]

PMID:
29998415
6.

A Soft Exosuit for Flexible Upper-Extremity Rehabilitation.

Lessard S, Pansodtee P, Robbins A, Trombadore JM, Kurniawan S, Teodorescu M.

IEEE Trans Neural Syst Rehabil Eng. 2018 Aug;26(8):1604-1617. doi: 10.1109/TNSRE.2018.2854219. Epub 2018 Jul 9.

PMID:
29994617
7.

Environmental Noise Could Promote Stochastic Local Stability of Behavioral Diversity Evolution.

Zheng XD, Li C, Lessard S, Tao Y.

Phys Rev Lett. 2018 May 25;120(21):218101. doi: 10.1103/PhysRevLett.120.218101.

PMID:
29883159
8.

DSP-free 'coherent-lite' transceiver for next generation single wavelength optical intra-datacenter interconnects.

Morsy-Osman M, Sowailem M, El-Fiky E, Goodwill T, Hoang T, Lessard S, Plant DV.

Opt Express. 2018 Apr 2;26(7):8890-8903. doi: 10.1364/OE.26.008890.

PMID:
29715850
9.

Detection of Aedes (Stegomyia) aegypti (Diptera: Culicidae) Populations in Southern Alabama Following a 26-yr Absence and Public Perceptions of the Threat of Zika Virus.

Zohdy S, Morse WC, Mathias D, Ashby V, Lessard S.

J Med Entomol. 2018 Aug 29;55(5):1319-1324. doi: 10.1093/jme/tjy050.

PMID:
29659928
10.

Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease.

Raffield LM, Ulirsch JC, Naik RP, Lessard S, Handsaker RE, Jain D, Kang HM, Pankratz N, Auer PL, Bao EL, Smith JD, Lange LA, Lange EM, Li Y, Thornton TA, Young BA, Abecasis GR, Laurie CC, Nickerson DA, McCarroll SA, Correa A, Wilson JG; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Hematology & Hemostasis, Diabetes, and Structural Variation TOPMed Working Groups, Lettre G, Sankaran VG, Reiner AP.

PLoS Genet. 2018 Mar 28;14(3):e1007293. doi: 10.1371/journal.pgen.1007293. eCollection 2018 Mar.

11.

14q32 and let-7 microRNAs regulate transcriptional networks in fetal and adult human erythroblasts.

Lessard S, Beaudoin M, Orkin SH, Bauer DE, Lettre G.

Hum Mol Genet. 2018 Apr 15;27(8):1411-1420. doi: 10.1093/hmg/ddy051.

PMID:
29432581
12.

Evolutionary stability concepts in a stochastic environment.

Zheng XD, Li C, Lessard S, Tao Y.

Phys Rev E. 2017 Sep;96(3-1):032414. doi: 10.1103/PhysRevE.96.032414. Epub 2017 Sep 25.

PMID:
29347009
13.

Frequency-dependent growth in class-structured populations: continuous dynamics in the limit of weak selection.

Lessard S, Soares CD.

J Math Biol. 2018 Jul;77(1):229-259. doi: 10.1007/s00285-017-1195-5. Epub 2017 Dec 13.

PMID:
29236142
14.

Human genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated loci.

Lessard S, Francioli L, Alfoldi J, Tardif JC, Ellinor PT, MacArthur DG, Lettre G, Orkin SH, Canver MC.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11257-E11266. doi: 10.1073/pnas.1714640114. Epub 2017 Dec 11.

15.

Flow stagnation volume and abdominal aortic aneurysm growth: Insights from patient-specific computational flow dynamics of Lagrangian-coherent structures.

Joly F, Soulez G, Garcia D, Lessard S, Kauffmann C.

Comput Biol Med. 2018 Jan 1;92:98-109. doi: 10.1016/j.compbiomed.2017.10.033. Epub 2017 Nov 6.

PMID:
29169074
16.

Clcn7F318L/+ as a new mouse model of Albers-Schönberg disease.

Caetano-Lopes J, Lessard SG, Hann S, Espinoza K, Kang KS, Lim KE, Horan DJ, Noonan HR, Hu D, Baron R, Robling AG, Warman ML.

Bone. 2017 Dec;105:253-261. doi: 10.1016/j.bone.2017.09.007. Epub 2017 Sep 20.

PMID:
28942122
17.

CRUX: A compliant robotic upper-extremity exosuit for lightweight, portable, multi-joint muscular augmentation.

Lessard S, Pansodtee P, Robbins A, Baltaxe-Admony LB, Trombadore JM, Teodorescu M, Agogino A, Kurniawan S.

IEEE Int Conf Rehabil Robot. 2017 Jul;2017:1633-1638. doi: 10.1109/ICORR.2017.8009482.

PMID:
28814054
18.

An erythroid-specific ATP2B4 enhancer mediates red blood cell hydration and malaria susceptibility.

Lessard S, Gatof ES, Beaudoin M, Schupp PG, Sher F, Ali A, Prehar S, Kurita R, Nakamura Y, Baena E, Ledoux J, Oceandy D, Bauer DE, Lettre G.

J Clin Invest. 2017 Aug 1;127(8):3065-3074. doi: 10.1172/JCI94378. Epub 2017 Jul 17.

19.

Frameshift indels introduced by genome editing can lead to in-frame exon skipping.

Lalonde S, Stone OA, Lessard S, Lavertu A, Desjardins J, Beaudoin M, Rivas M, Stainier DYR, Lettre G.

PLoS One. 2017 Jun 1;12(6):e0178700. doi: 10.1371/journal.pone.0178700. eCollection 2017.

20.

Multispecies mass mortality of marine fauna linked to a toxic dinoflagellate bloom.

Starr M, Lair S, Michaud S, Scarratt M, Quilliam M, Lefaivre D, Robert M, Wotherspoon A, Michaud R, Ménard N, Sauvé G, Lessard S, Béland P, Measures L.

PLoS One. 2017 May 4;12(5):e0176299. doi: 10.1371/journal.pone.0176299. eCollection 2017.

21.

Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.

Canver MC, Lessard S, Pinello L, Wu Y, Ilboudo Y, Stern EN, Needleman AJ, Galactéros F, Brugnara C, Kutlar A, McKenzie C, Reid M, Chen DD, Das PP, A Cole M, Zeng J, Kurita R, Nakamura Y, Yuan GC, Lettre G, Bauer DE, Orkin SH.

Nat Genet. 2017 Apr;49(4):625-634. doi: 10.1038/ng.3793. Epub 2017 Feb 20.

22.

Circulating MicroRNA Are Predictive of Aging and Acute Adaptive Response to Resistance Exercise in Men.

Margolis LM, Lessard SJ, Ezzyat Y, Fielding RA, Rivas DA.

J Gerontol A Biol Sci Med Sci. 2017 Oct 1;72(10):1319-1326. doi: 10.1093/gerona/glw243.

23.

Through-Space Shielding Effects of Metal-Complexed Phenyl Rings.

Miles WH, Robinson MJ, Lessard SG, Thamattoor DM.

J Org Chem. 2016 Nov 18;81(22):10791-10801. Epub 2016 Oct 27.

PMID:
27754676
24.

A coalescent dual process for a Wright-Fisher diffusion with recombination and its application to haplotype partitioning.

Griffiths RC, Jenkins PA, Lessard S.

Theor Popul Biol. 2016 Dec;112:126-138. doi: 10.1016/j.tpb.2016.08.007. Epub 2016 Sep 1.

PMID:
27594345
25.

External facilitators and interprofessional facilitation teams: a qualitative study of their roles in supporting practice change.

Lessard S, Bareil C, Lalonde L, Duhamel F, Hudon E, Goudreau J, Lévesque L.

Implement Sci. 2016 Jul 16;11:97. doi: 10.1186/s13012-016-0458-7.

26.

Glass interposer for short reach optical connectivity.

Mirshafiei M, Bérubé JP, Lessard S, Vallée R, Plant DV.

Opt Express. 2016 May 30;24(11):12375-84. doi: 10.1364/OE.24.012375.

PMID:
27410152
27.

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.

Chami N, Chen MH, Slater AJ, Eicher JD, Evangelou E, Tajuddin SM, Love-Gregory L, Kacprowski T, Schick UM, Nomura A, Giri A, Lessard S, Brody JA, Schurmann C, Pankratz N, Yanek LR, Manichaikul A, Pazoki R, Mihailov E, Hill WD, Raffield LM, Burt A, Bartz TM, Becker DM, Becker LC, Boerwinkle E, Bork-Jensen J, Bottinger EP, O'Donoghue ML, Crosslin DR, de Denus S, Dubé MP, Elliott P, Engström G, Evans MK, Floyd JS, Fornage M, Gao H, Greinacher A, Gudnason V, Hansen T, Harris TB, Hayward C, Hernesniemi J, Highland HM, Hirschhorn JN, Hofman A, Irvin MR, Kähönen M, Lange E, Launer LJ, Lehtimäki T, Li J, Liewald DC, Linneberg A, Liu Y, Lu Y, Lyytikäinen LP, Mägi R, Mathias RA, Melander O, Metspalu A, Mononen N, Nalls MA, Nickerson DA, Nikus K, O'Donnell CJ, Orho-Melander M, Pedersen O, Petersmann A, Polfus L, Psaty BM, Raitakari OT, Raitoharju E, Richard M, Rice KM, Rivadeneira F, Rotter JI, Schmidt F, Smith AV, Starr JM, Taylor KD, Teumer A, Thuesen BH, Torstenson ES, Tracy RP, Tzoulaki I, Zakai NA, Vacchi-Suzzi C, van Duijn CM, van Rooij FJ, Cushman M, Deary IJ, Velez Edwards DR, Vergnaud AC, Wallentin L, Waterworth DM, White HD, Wilson JG, Zonderman AB, Kathiresan S, Grarup N, Esko T, Loos RJ, Lange LA, Faraday N, Abumrad NA, Edwards TL, Ganesh SK, Auer PL, Johnson AD, Reiner AP, Lettre G.

Am J Hum Genet. 2016 Jul 7;99(1):8-21. doi: 10.1016/j.ajhg.2016.05.007. Epub 2016 Jun 23.

28.

Lower Methylation of the ANGPTL2 Gene in Leukocytes from Post-Acute Coronary Syndrome Patients.

Nguyen A, Mamarbachi M, Turcot V, Lessard S, Yu C, Luo X, Lalongé J, Hayami D, Gayda M, Juneau M, Thorin-Trescases N, Lettre G, Nigam A, Thorin E.

PLoS One. 2016 Apr 21;11(4):e0153920. doi: 10.1371/journal.pone.0153920. eCollection 2016.

29.

Fixation probability in a two-locus intersexual selection model.

Durand G, Lessard S.

Theor Popul Biol. 2016 Jun;109:75-87. doi: 10.1016/j.tpb.2016.03.004. Epub 2016 Apr 5.

PMID:
27059474
30.

Testing the role of predicted gene knockouts in human anthropometric trait variation.

Lessard S, Manning AK, Low-Kam C, Auer PL, Giri A, Graff M, Schurmann C, Yaghootkar H, Luan J, Esko T, Karaderi T; NHLBI GO Exome Sequence Project; GOT2D; T2D-GENES; GIANT Consortium, Bottinger EP, Lu Y, Carlson C, Caulfield M, Dubé MP, Jackson RD, Kooperberg C, McKnight B, Mongrain I, Peters U, Reiner AP, Rhainds D, Sotoodehnia N, Hirschhorn JN, Scott RA, Munroe PB, Frayling TM, Loos RJ, North KE, Edwards TL, Tardif JC, Lindgren CM, Lettre G.

Hum Mol Genet. 2016 May 15;25(10):2082-2092. Epub 2016 Feb 21.

31.

The AMPK-related kinase SNARK regulates muscle mass and myocyte survival.

Lessard SJ, Rivas DA, So K, Koh HJ, Queiroz AL, Hirshman MF, Fielding RA, Goodyear LJ.

J Clin Invest. 2016 Feb;126(2):560-70.

32.

Definitions of fitness in age-structured populations: Comparison in the haploid case.

Lessard S, Soares C.

J Theor Biol. 2016 Feb 21;391:65-73. doi: 10.1016/j.jtbi.2015.11.017. Epub 2015 Dec 10.

33.

Facilitating Implementation of Interprofessional Collaborative Practices Into Primary Care: A Trilogy of Driving Forces.

Bareil C, Duhamel F, Lalonde L, Goudreau J, Hudon E, Lussier MT, Lévesque L, Lessard S, Turcotte A, Lalonde G.

J Healthc Manag. 2015 Jul-Aug;60(4):287-300.

PMID:
26364352
34.

Automatic detection of selective arterial devices for advanced visualization during abdominal aortic aneurysm endovascular repair.

Lessard S, Kauffmann C, Pfister M, Cloutier G, Thérasse É, de Guise JA, Soulez G.

Med Eng Phys. 2015 Oct;37(10):979-86. doi: 10.1016/j.medengphy.2015.07.007. Epub 2015 Sep 9.

PMID:
26362721
35.

On the interpretation and relevance of the Fundamental Theorem of Natural Selection.

Ewens WJ, Lessard S.

Theor Popul Biol. 2015 Sep;104:59-67. doi: 10.1016/j.tpb.2015.07.002. Epub 2015 Jul 26.

PMID:
26220589
36.

Lubricin restoration in a mouse model of congenital deficiency.

Hill A, Waller KA, Cui Y, Allen JM, Smits P, Zhang LX, Ayturk UM, Hann S, Lessard SG, Zurakowski D, Warman ML, Jay GD.

Arthritis Rheumatol. 2015 Nov;67(11):3070-81. doi: 10.1002/art.39276.

37.

Evolution of cooperation in a multidimensional phenotype space.

Kroumi D, Lessard S.

Theor Popul Biol. 2015 Jun;102:60-75. doi: 10.1016/j.tpb.2015.03.007. Epub 2015 Apr 3.

PMID:
25847145
38.

Source of errors and accuracy of a two-dimensional/three-dimensional fusion road map for endovascular aneurysm repair of abdominal aortic aneurysm.

Kauffmann C, Douane F, Therasse E, Lessard S, Elkouri S, Gilbert P, Beaudoin N, Pfister M, Blair JF, Soulez G.

J Vasc Interv Radiol. 2015 Apr;26(4):544-51. doi: 10.1016/j.jvir.2014.12.019. Epub 2015 Feb 24.

PMID:
25724087
39.

Comparison of DNA methylation profiles in human fetal and adult red blood cell progenitors.

Lessard S, Beaudoin M, Benkirane K, Lettre G.

Genome Med. 2015 Jan 20;7(1):1. doi: 10.1186/s13073-014-0122-2. eCollection 2015.

40.

Experimental study of 112 Gb/s short reach transmission employing PAM formats and SiP intensity modulator at 1.3 μm.

Chagnon M, Osman M, Poulin M, Latrasse C, Gagné JF, Painchaud Y, Paquet C, Lessard S, Plant D.

Opt Express. 2014 Aug 25;22(17):21018-36. doi: 10.1364/OE.22.021018.

PMID:
25321303
41.

Diminished skeletal muscle microRNA expression with aging is associated with attenuated muscle plasticity and inhibition of IGF-1 signaling.

Rivas DA, Lessard SJ, Rice NP, Lustgarten MS, So K, Goodyear LJ, Parnell LD, Fielding RA.

FASEB J. 2014 Sep;28(9):4133-47. doi: 10.1096/fj.14-254490. Epub 2014 Jun 13.

42.

The effectiveness of interdisciplinary teams in end-of-life palliative care: a systematic review of comparative studies.

Leclerc BS, Blanchard L, Cantinotti M, Couturier Y, Gervais D, Lessard S, Mongeau S.

J Palliat Care. 2014 Spring;30(1):44-54. Review. No abstract available.

PMID:
24826443
43.

Overexpression of TRB3 in muscle alters muscle fiber type and improves exercise capacity in mice.

An D, Lessard SJ, Toyoda T, Lee MY, Koh HJ, Qi L, Hirshman MF, Goodyear LJ.

Am J Physiol Regul Integr Comp Physiol. 2014 Jun 15;306(12):R925-33. doi: 10.1152/ajpregu.00027.2014. Epub 2014 Apr 16.

44.

Attitudes toward death, dying, end-of-life palliative care, and interdisciplinary practice in long term care workers.

Leclerc BS, Lessard S, Bechennec C, Le Gal E, Benoit S, Bellerose L.

J Am Med Dir Assoc. 2014 Mar;15(3):207-213. doi: 10.1016/j.jamda.2013.11.017. Epub 2014 Jan 23. Erratum in: J Am Med Dir Assoc. 2014 Jun;15(6):446.

PMID:
24461725
45.

An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.

Bauer DE, Kamran SC, Lessard S, Xu J, Fujiwara Y, Lin C, Shao Z, Canver MC, Smith EC, Pinello L, Sabo PJ, Vierstra J, Voit RA, Yuan GC, Porteus MH, Stamatoyannopoulos JA, Lettre G, Orkin SH.

Science. 2013 Oct 11;342(6155):253-7. doi: 10.1126/science.1242088.

46.

Exercise training enhances white adipose tissue metabolism in rats selectively bred for low- or high-endurance running capacity.

Stephenson EJ, Lessard SJ, Rivas DA, Watt MJ, Yaspelkis BB 3rd, Koch LG, Britton SL, Hawley JA.

Am J Physiol Endocrinol Metab. 2013 Aug 1;305(3):E429-38. doi: 10.1152/ajpendo.00544.2012. Epub 2013 Jun 11.

47.

Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks.

Lessard SJ, Rivas DA, Alves-Wagner AB, Hirshman MF, Gallagher IJ, Constantin-Teodosiu D, Atkins R, Greenhaff PL, Qi NR, Gustafsson T, Fielding RA, Timmons JA, Britton SL, Koch LG, Goodyear LJ.

Diabetes. 2013 Aug;62(8):2717-27. doi: 10.2337/db13-0062. Epub 2013 Apr 22.

48.

Marine mammal strandings and environmental changes: a 15-year study in the St. Lawrence ecosystem.

Truchon MH, Measures L, L'Hérault V, Brêthes JC, Galbraith PS, Harvey M, Lessard S, Starr M, Lecomte N.

PLoS One. 2013;8(3):e59311. doi: 10.1371/journal.pone.0059311. Epub 2013 Mar 27.

49.

The long-term clinical benefit and effectiveness of switching to once-daily quetiapine extended release in patients with schizophrenia.

Chue P, Malla A, Bouchard RH, Lessard S, Ganesan S, Stip E, Johnson S, Chen E, Ahn YM, Kim YS, Robinson G, Schweikert C, Gendron A, Eriksson H; SPECTRUM XR Study Group.

Curr Med Res Opin. 2013 Mar;29(3):227-39. doi: 10.1185/03007995.2012.762903. Epub 2013 Jan 22.

PMID:
23281876
50.

Low intrinsic exercise capacity in rats predisposes to age-dependent cardiac remodeling independent of macrovascular function.

Ritchie RH, Leo CH, Qin C, Stephenson EJ, Bowden MA, Buxton KD, Lessard SJ, Rivas DA, Koch LG, Britton SL, Hawley JA, Woodman OL.

Am J Physiol Heart Circ Physiol. 2013 Mar 1;304(5):H729-39. doi: 10.1152/ajpheart.00638.2012. Epub 2012 Dec 21.

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