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Items: 1 to 50 of 66

1.

Comparative study of the effects of ortho-, meta- and para-carboranes (C2B10H12) on the physicochemical properties, cytotoxicity and antiviral activity of uridine and 2'-deoxyuridine boron cluster conjugates.

Saftić D, Studzińska M, Paradowska E, Piantanida I, Baranović G, Białek-Pietras M, Leśnikowski ZJ.

Bioorg Chem. 2020 Jan;94:103466. doi: 10.1016/j.bioorg.2019.103466. Epub 2019 Nov 29.

PMID:
31826808
2.

Boron clusters as a platform for new materials: composites of nucleic acids and oligofunctionalized carboranes (C2B10H12) and their assembly into functional nanoparticles.

Kaniowski D, Ebenryter-Olbinska K, Kulik K, Janczak S, Maciaszek A, Bednarska-Szczepaniak K, Nawrot B, Lesnikowski Z.

Nanoscale. 2020 Jan 7;12(1):103-114. doi: 10.1039/c9nr06550d. Epub 2019 Nov 25.

PMID:
31763634
3.

Comparative study of inorganic, boron-rich cluster and organic, phenyl adenosine modifications: synthesis and properties.

Mieczkowski A, Kierozalska A, Białek-Pietras M, Goszczyński TM, Janczak S, Olejniczak AB, Studzińska M, Paradowska E, Leśnikowski ZJ.

Future Med Chem. 2019 Jun;11(11):1267-1284. doi: 10.4155/fmc-2018-0517. Epub 2019 Jun 10.

PMID:
31180247
4.

EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology.

Brennecke P, Rasina D, Aubi O, Herzog K, Landskron J, Cautain B, Vicente F, Quintana J, Mestres J, Stechmann B, Ellinger B, Brea J, Kolanowski JL, Pilarski R, Orzaez M, Pineda-Lucena A, Laraia L, Nami F, Zielenkiewicz P, Paruch K, Hansen E, von Kries JP, Neuenschwander M, Specker E, Bartunek P, Simova S, Leśnikowski Z, Krauss S, Lehtiö L, Bilitewski U, Brönstrup M, Taskén K, Jirgensons A, Lickert H, Clausen MH, Andersen JH, Vicent MJ, Genilloud O, Martinez A, Nazaré M, Fecke W, Gribbon P.

SLAS Discov. 2019 Mar;24(3):398-413. doi: 10.1177/2472555218816276. Epub 2019 Jan 7.

5.

Synthesis and in vitro evaluation of antiviral and cytostatic properties of novel 8-triazolyl acyclovir derivatives.

Saftić D, Žinić B, Glavaš-Obrovac L, Studzińska M, Paradowska E, Leśnikowski ZJ.

Nucleosides Nucleotides Nucleic Acids. 2018;37(7):397-414. doi: 10.1080/15257770.2018.1485932. Epub 2018 Nov 17.

PMID:
30449256
6.

DNA Modified with Boron⁻Metal Cluster Complexes [M(C₂B₉H11)₂]-Synthesis, Properties, and Applications.

Olejniczak AB, Nawrot B, Leśnikowski ZJ.

Int J Mol Sci. 2018 Nov 7;19(11). pii: E3501. doi: 10.3390/ijms19113501. Review.

7.
8.

Carborane-linked 2'-deoxyuridine 5'-O-triphosphate as building block for polymerase synthesis of carborane-modified DNA.

Balintová J, Simonova A, Białek-Pietras M, Olejniczak A, Lesnikowski ZJ, Hocek M.

Bioorg Med Chem Lett. 2017 Nov 1;27(21):4786-4788. doi: 10.1016/j.bmcl.2017.09.064. Epub 2017 Sep 30.

PMID:
29017785
9.

Versatile Method for the Site-Specific Modification of DNA with Boron Clusters: Anti-Epidermal Growth Factor Receptor (EGFR) Antisense Oligonucleotide Case.

Ebenryter-Olbińska K, Kaniowski D, Sobczak M, Wojtczak BA, Janczak S, Wielgus E, Nawrot B, Leśnikowski ZJ.

Chemistry. 2017 Nov 21;23(65):16535-16546. doi: 10.1002/chem.201702957. Epub 2017 Oct 30.

PMID:
28881435
10.

Interactions of Boron Clusters and their Derivatives with Serum Albumin.

Goszczyński TM, Fink K, Kowalski K, Leśnikowski ZJ, Boratyński J.

Sci Rep. 2017 Aug 29;7(1):9800. doi: 10.1038/s41598-017-10314-0.

11.

High Boron-loaded DNA-Oligomers as Potential Boron Neutron Capture Therapy and Antisense Oligonucleotide Dual-Action Anticancer Agents.

Kaniowski D, Ebenryter-Olbińska K, Sobczak M, Wojtczak B, Janczak S, Leśnikowski ZJ, Nawrot B.

Molecules. 2017 Aug 23;22(9). pii: E1393. doi: 10.3390/molecules22091393.

12.

Cytomegalovirus DNA is highly prevalent in the blood of patients with asthma and is associated with age and asthma traits.

Kowalski ML, Wardzynska A, Studzinska M, Pawelczyk M, Lesnikowski ZJ, Paradowska E.

Allergy. 2017 Dec;72(12):2035-2038. doi: 10.1111/all.13233. Epub 2017 Jul 12.

PMID:
28643373
13.

Association of TLR3 L412F Polymorphism with Cytomegalovirus Infection in Children.

Studzińska M, Jabłońska A, Wiśniewska-Ligier M, Nowakowska D, Gaj Z, Leśnikowski ZJ, Woźniakowska-Gęsicka T, Wilczyński J, Paradowska E.

PLoS One. 2017 Jan 3;12(1):e0169420. doi: 10.1371/journal.pone.0169420. eCollection 2017.

14.

In vitro antileukemic activity of novel adenosine derivatives bearing boron cluster modification.

Żołnierczyk JD, Olejniczak AB, Mieczkowski A, Błoński JZ, Kiliańska ZM, Robak T, Leśnikowski ZJ.

Bioorg Med Chem. 2016 Nov 1;24(21):5076-5087. doi: 10.1016/j.bmc.2016.08.028. Epub 2016 Aug 20.

PMID:
27600403
15.

Anti-mycobacterial activity of thymine derivatives bearing boron clusters.

Adamska A, Rumijowska-Galewicz A, Ruszczynska A, Studzińska M, Jabłońska A, Paradowska E, Bulska E, Munier-Lehmann H, Dziadek J, Leśnikowski ZJ, Olejniczak AB.

Eur J Med Chem. 2016 Oct 4;121:71-81. doi: 10.1016/j.ejmech.2016.05.030. Epub 2016 May 15.

PMID:
27236064
16.

Challenges and Opportunities for the Application of Boron Clusters in Drug Design.

Leśnikowski ZJ.

J Med Chem. 2016 Sep 8;59(17):7738-58. doi: 10.1021/acs.jmedchem.5b01932. Epub 2016 May 10. Review.

PMID:
27124656
17.

TLR9 -1486T/C and 2848C/T SNPs Are Associated with Human Cytomegalovirus Infection in Infants.

Paradowska E, Jabłońska A, Studzińska M, Skowrońska K, Suski P, Wiśniewska-Ligier M, Woźniakowska-Gęsicka T, Nowakowska D, Gaj Z, Wilczyński J, Leśnikowski ZJ.

PLoS One. 2016 Apr 22;11(4):e0154100. doi: 10.1371/journal.pone.0154100. eCollection 2016.

18.

Recent developments with boron as a platform for novel drug design.

Leśnikowski ZJ.

Expert Opin Drug Discov. 2016 Jun;11(6):569-78. doi: 10.1080/17460441.2016.1174687. Epub 2016 Apr 21. Review.

PMID:
27080414
19.

Boron Clusters as a Platform for New Materials: Synthesis of Functionalized o-Carborane (C2 B10 H12 ) Derivatives Incorporating DNA Fragments.

Janczak S, Olejniczak A, Balabańska S, Chmielewski MK, Lupu M, Viñas C, Lesnikowski ZJ.

Chemistry. 2015 Oct 19;21(43):15118-22. doi: 10.1002/chem.201502822. Epub 2015 Sep 8.

PMID:
26346614
20.

TLR9 2848 GA heterozygotic status possibly predisposes fetuses and newborns to congenital infection with human cytomegalovirus.

Wujcicka W, Paradowska E, Studzińska M, Gaj Z, Wilczyński J, Leśnikowski Z, Nowakowska D.

PLoS One. 2015 Apr 6;10(4):e0122831. doi: 10.1371/journal.pone.0122831. eCollection 2015.

21.

Human parainfluenza virus type 3 (HPIV3) induces production of IFNγ and RANTES in human nasal epithelial cells (HNECs).

Lewandowska-Polak A, Brauncajs M, Paradowska E, Jarzębska M, Kurowski M, Moskwa S, Leśnikowski ZJ, Kowalski ML.

J Inflamm (Lond). 2015 Feb 21;12:16. doi: 10.1186/s12950-015-0054-7. eCollection 2015.

22.

Synthesis of lysozyme-metallacarborane conjugates and the effect of boron cluster modification on protein structure and function.

Kowalski K, Goszczyński T, Leśnikowski ZJ, Boratyński J.

Chembiochem. 2015 Feb 9;16(3):424-31. doi: 10.1002/cbic.201402611. Epub 2015 Jan 14.

PMID:
25589498
23.

Synthesis and the structure of 8-tetrahydrofuronium and 8-tetrahydropyronium derivatives of iron bis(dicarbollide)(-I) and their cleavage reactions.

Lobanova I, Kosenko I, Laskova J, Ananyev I, Druzina A, Godovikov I, Bregadze VI, Qi S, Leśnikowski ZJ, Semioshkin A.

Dalton Trans. 2015 Jan 28;44(4):1571-84. doi: 10.1039/c4dt03015j.

PMID:
25464946
24.

Solid state, thermal synthesis of site-specific protein-boron cluster conjugates and their physicochemical and biochemical properties.

Goszczyński TM, Kowalski K, Leśnikowski ZJ, Boratyński J.

Biochim Biophys Acta. 2015 Feb;1850(2):411-8. doi: 10.1016/j.bbagen.2014.11.015. Epub 2014 Nov 20.

PMID:
25445715
25.

Mixed infections with distinct cytomegalovirus glycoprotein B genotypes in Polish pregnant women, fetuses, and newborns.

Rycel M, Wujcicka W, Zawilińska B, Paradowska E, Suski P, Gaj Z, Wilczyński J, Leśnikowski Z, Nowakowska D.

Eur J Clin Microbiol Infect Dis. 2015 Mar;34(3):585-91. doi: 10.1007/s10096-014-2266-9. Epub 2014 Oct 28.

26.

Cytomegalovirus alpha-chemokine genotypes are associated with clinical manifestations in children with congenital or postnatal infections.

Paradowska E, Jabłońska A, Płóciennikowska A, Studzińska M, Suski P, Wiśniewska-Ligier M, Dzierżanowska-Fangrat K, Kasztelewicz B, Woźniakowska-Gęsicka T, Leśnikowski ZJ.

Virology. 2014 Aug;462-463:207-17. doi: 10.1016/j.virol.2014.06.020. Epub 2014 Jul 5.

27.

Modulation of human neutrophil activity by adenosine modified with a carborane pharmacophore.

Bednarska K, Olejniczak AB, Klink M, Sułowska Z, Leśnikowski ZJ.

Bioorg Med Chem Lett. 2014 Jul 15;24(14):3073-8. doi: 10.1016/j.bmcl.2014.05.010. Epub 2014 May 16.

PMID:
24881569
28.

Relationship between toll-like receptor 2 Arg677Trp and Arg753Gln and toll-like receptor 4 Asp299Gly polymorphisms and cytomegalovirus infection.

Jabłońska A, Paradowska E, Studzińska M, Suski P, Nowakowska D, Wiśniewska-Ligier M, Woźniakowska-Gęsicka T, Wilczyński J, Leśnikowski ZJ.

Int J Infect Dis. 2014 Aug;25:11-5. doi: 10.1016/j.ijid.2014.04.001. Epub 2014 May 9.

29.

Cytomegalovirus glycoprotein H genotype distribution and the relationship with hearing loss in children.

Paradowska E, Jabłońska A, Studzińska M, Kasztelewicz B, Zawilińska B, Wiśniewska-Ligier M, Dzierżanowska-Fangrat K, Woźniakowska-Gęsicka T, Kosz-Vnenchak M, Leśnikowski ZJ.

J Med Virol. 2014 Aug;86(8):1421-7. doi: 10.1002/jmv.23906. Epub 2014 Feb 21.

PMID:
24615599
30.

Decrease in 3-nitrotyrosine in the amniotic fluid of women with cytomegalovirus infection.

Gaj Z, Wilczynski J, Nowakowska-Glab A, Boakye-Agyeman F, Paradowska E, Lesnikowski ZJ, Nowakowska D.

J Obstet Gynaecol. 2014 Apr;34(3):251-4. doi: 10.3109/01443615.2013.851656. Epub 2014 Jan 31.

PMID:
24483707
31.

Phosphorylation of nucleoside-metallacarborane and carborane conjugates by nucleoside kinases.

Wojtczak BA, Olejniczak AB, Wang L, Eriksson S, Lesnikowski ZJ.

Nucleosides Nucleotides Nucleic Acids. 2013;32(10):571-88. doi: 10.1080/15257770.2013.838259.

PMID:
24124690
32.

DNA probe modified with 3-iron bis(dicarbollide) for electrochemical determination of DNA sequence of Avian Influenza Virus H5N1.

Grabowska I, Stachyra A, Góra-Sochacka A, Sirko A, Olejniczak AB, Leśnikowski ZJ, Radecki J, Radecka H.

Biosens Bioelectron. 2014 Jan 15;51:170-6. doi: 10.1016/j.bios.2013.07.026. Epub 2013 Jul 21. Erratum in: Biosens Bioelectron. 2014 Aug 15;58:403.

PMID:
23958581
33.

Distribution of cytomegalovirus gN variants and associated clinical sequelae in infants.

Paradowska E, Jabłońska A, Studzińska M, Suski P, Kasztelewicz B, Zawilińska B, Wiśniewska-Ligier M, Dzierżanowska-Fangrat K, Woźniakowska-Gęsicka T, Czech-Kowalska J, Lipka B, Kornacka M, Pawlik D, Tomasik T, Kosz-Vnenchak M, Leśnikowski ZJ.

J Clin Virol. 2013 Sep;58(1):271-5. doi: 10.1016/j.jcv.2013.05.024. Epub 2013 Jun 25.

PMID:
23806667
34.

Modification of selected anti-HCMV drugs with lipophilic boron cluster modulator.

Olejniczak AB, Adamska AM, Paradowska E, Studzinska M, Suski P, Leśnikowski ZJ.

Acta Pol Pharm. 2013 May-Jun;70(3):489-504.

35.

siRNAs modified with boron cluster and their physicochemical and biological characterization.

Kwiatkowska A, Sobczak M, Mikolajczyk B, Janczak S, Olejniczak AB, Sochacki M, Lesnikowski ZJ, Nawrot B.

Bioconjug Chem. 2013 Jun 19;24(6):1017-26. doi: 10.1021/bc400059y. Epub 2013 May 29.

PMID:
23682800
36.

Towards new boron carriers for boron neutron capture therapy: metallacarboranes bearing cobalt, iron and chromium and their cholesterol conjugates.

Białek-Pietras M, Olejniczak AB, Tachikawa S, Nakamura H, Leśnikowski ZJ.

Bioorg Med Chem. 2013 Mar 1;21(5):1136-42. doi: 10.1016/j.bmc.2012.12.039. Epub 2013 Jan 5.

PMID:
23357039
37.

Oseltamivir analog with boron cluster modulator.

Adamska A, Olejniczak AB, Zwoliński K, Szczepek WJ, Król E, Szewczyk B, Grynkiewicz G, Leśnikowski ZJ.

Acta Pol Pharm. 2012 Nov-Dec;69(6):1218-23.

38.

Effect of adenosine modified with a boron cluster pharmacophore on reactive oxygen species production by human neutrophils.

Bednarska K, Olejniczak AB, Piskala A, Klink M, Sulowska Z, Lesnikowski ZJ.

Bioorg Med Chem. 2012 Nov 15;20(22):6621-9. doi: 10.1016/j.bmc.2012.09.039. Epub 2012 Sep 25.

PMID:
23063523
39.

Electrochemical detection of DNA hybridization using metallacarborane unit.

Ziółkowski R, Olejniczak AB, Górski Ł, Janusik J, Leśnikowski ZJ, Malinowska E.

Bioelectrochemistry. 2012 Oct;87:78-83. doi: 10.1016/j.bioelechem.2011.10.005. Epub 2011 Nov 4.

PMID:
22104629
40.

Distribution of UL144, US28 and UL55 genotypes in Polish newborns with congenital cytomegalovirus infections.

Paradowska E, Studzińska M, Nowakowska D, Wilczyński J, Rycel M, Suski P, Gaj Z, Kaczmarek B, Zbróg Z, Leśnikowski ZJ.

Eur J Clin Microbiol Infect Dis. 2012 Jul;31(7):1335-45. doi: 10.1007/s10096-011-1447-z. Epub 2011 Nov 4.

PMID:
22048843
41.

Adenosine and 2'-deoxyadenosine modified with boron cluster pharmacophores as new classes of human blood platelet function modulators.

Bednarska K, Olejniczak AB, Wojtczak BA, Sułowska Z, Leśnikowski ZJ.

ChemMedChem. 2010 May 3;5(5):749-56. doi: 10.1002/cmdc.201000075.

PMID:
20373324
42.

Nucleoside modification with boron clusters and their metal complexes.

Wojtczak BA, Olejniczak AB, Lesnikowski ZJ.

Curr Protoc Nucleic Acid Chem. 2009 Sep;Chapter 4:Unit 4.37 1-26. doi: 10.1002/0471142700.nc0437s38.

PMID:
19746357
43.

Electrochemical DNA detection based on the polyhedral boron cluster label.

Jelen F, Olejniczak AB, Kourilova A, Lesnikowski ZJ, Palecek E.

Anal Chem. 2009 Jan 15;81(2):840-4. doi: 10.1021/ac801235b.

PMID:
19072584
44.

"Chemical ligation": a versatile method for nucleoside modification with boron clusters.

Wojtczak BA, Andrysiak A, Grüner B, Lesnikowski ZJ.

Chemistry. 2008;14(34):10675-82. doi: 10.1002/chem.200801053.

PMID:
18942698
45.

Aggregation behavior of nucleoside-boron cluster conjugates in aqueous solutions.

Matejícek P, Cígler P, Olejniczak AB, Andrysiak A, Wojtczak B, Prochazka K, Lesnikowski ZJ.

Langmuir. 2008 Mar 18;24(6):2625-30. doi: 10.1021/la702852e. Epub 2008 Feb 8.

PMID:
18257589
46.

2'-deoxyadenosine bearing hydrophobic carborane pharmacophore.

Olejniczak A, Wojtczak B, Lesnikowski ZJ.

Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1611-3.

PMID:
18066837
47.

Nucleoside-metallacarborane conjugates for base-specific metal labeling of DNA.

Olejniczak AB, Plesek J, Leśnikowski ZJ.

Chemistry. 2007;13(1):311-8.

PMID:
17103465
48.

Detection of cytomegalovirus in human placental cells by polymerase chain reaction.

Paradowska E, Przepiórkiewicz M, Nowakowska D, Studzińska M, Wilczyński J, Emery VC, Leśnikowski ZJ.

APMIS. 2006 Nov;114(11):764-71.

PMID:
17078856
49.

Towards new boron carriers for boron neutron capture therapy: metallacarboranes and their nucleoside conjugates.

Leśnikowski ZJ, Paradowska E, Olejniczak AB, Studzińska M, Seekamp P, Schüssler U, Gabel D, Schinazi RF, Plesek J.

Bioorg Med Chem. 2005 Jul 1;13(13):4168-75.

PMID:
15878666
50.

A nucleoside conjugate containing a metallacarborane group and its incorporation into a DNA oligonucleotide.

Olejniczak AB, Plesek J, Kriz O, Lesnikowski ZJ.

Angew Chem Int Ed Engl. 2003 Dec 1;42(46):5740-3. No abstract available.

PMID:
14661211

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