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Items: 1 to 50 of 62

1.

Targeted invalidation of SR-B1 in macrophages reduces macrophage apoptosis and accelerates atherosclerosis.

Galle-Treger L, Moreau M, Ballaire R, Poupel L, Huby T, Sasso E, Troise F, Poti F, Lesnik P, Goff WL, Gautier EL, Huby T.

Cardiovasc Res. 2019 May 22. pii: cvz138. doi: 10.1093/cvr/cvz138. [Epub ahead of print]

PMID:
31119270
2.

Interleukin-18 serum levels in sepsis: Correlation with disease severity and inflammatory markers.

Mierzchala-Pasierb M, Krzystek-Korpacka M, Lesnik P, Adamik B, Placzkowska S, Serek P, Gamian A, Lipinska-Gediga M.

Cytokine. 2019 Aug;120:22-27. doi: 10.1016/j.cyto.2019.04.003. Epub 2019 Apr 16.

PMID:
31003186
3.

Cardiovascular Insufficiency, Abdominal Sepsis, and Patients' Age Are Associated with Decreased Paraoxonase-1 (PON1) Activity in Critically Ill Patients with Multiple Organ Dysfunction Syndrome (MODS).

Bednarz-Misa I, Mierzchala-Pasierb M, Lesnik P, Placzkowska S, Kedzior K, Gamian A, Krzystek-Korpacka M.

Dis Markers. 2019 Feb 11;2019:1314623. doi: 10.1155/2019/1314623. eCollection 2019.

4.

Association of Serum Cholesterol Efflux Capacity With Mortality in Patients With ST-Segment Elevation Myocardial Infarction.

Guerin M, Silvain J, Gall J, Darabi M, Berthet M, Frisdal E, Hauguel-Moreau M, Zeitouni M, Kerneis M, Lattuca B, Brugier D, Collet JP, Lesnik P, Montalescot G.

J Am Coll Cardiol. 2018 Dec 25;72(25):3259-3269. doi: 10.1016/j.jacc.2018.09.080.

PMID:
30573028
5.

Cholesterol efflux capacity of large, small and total HDL particles is unaltered by atorvastatin in patients with type 2 diabetes.

Muñoz-Hernandez L, Ortiz-Bautista RJ, Brito-Córdova G, Lozano-Arvizu F, Saucedo S, Pérez-Méndez O, Zentella-Dehesa A, Dauteuille C, Lhomme M, Lesnik P, Chapman MJ, Kontush A, Aguilar Salinas CA.

Atherosclerosis. 2018 Oct;277:72-79. doi: 10.1016/j.atherosclerosis.2018.08.027. Epub 2018 Aug 24.

PMID:
30176567
6.

Hypoalphalipoproteinemia and BRAFV600E Mutation Are Major Predictors of Aortic Infiltration in the Erdheim-Chester Disease.

Cohen-Aubart F, Guerin M, Poupel L, Cluzel P, Saint-Charles F, Charlotte F, Arsafi Y, Emile JF, Frisdal E, Le Goff C, Donadieu J, Amoura Z, Lesnik P, Haroche J, Le Goff W.

Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1913-1925. doi: 10.1161/ATVBAHA.118.310803.

PMID:
29930009
7.

A targeted genotyping approach enhances identification of variants in taste receptor and appetite/reward genes of potential functional importance for obesity-related porcine traits.

Cirera S, Clop A, Jacobsen MJ, Guerin M, Lesnik P, Jørgensen CB, Fredholm M, Karlskov-Mortensen P.

Anim Genet. 2018 Apr;49(2):110-118. doi: 10.1111/age.12641. Epub 2018 Feb 14.

PMID:
29441627
8.

Small dense HDLs display potent vasorelaxing activity, reflecting their elevated content of sphingosine-1-phosphate.

Perségol L, Darabi M, Dauteuille C, Lhomme M, Chantepie S, Rye KA, Therond P, Chapman MJ, Salvayre R, Nègre-Salvayre A, Lesnik P, Monier S, Kontush A.

J Lipid Res. 2018 Jan;59(1):25-34. doi: 10.1194/jlr.M076927. Epub 2017 Nov 17.

9.

Immune disorders in sepsis and their treatment as a significant problem of modern intensive care.

Łysenko L, Leśnik P, Nelke K, Gerber H.

Postepy Hig Med Dosw (Online). 2017 Aug 22;71(1):703-712.

PMID:
28894043
10.

Modulation of Gr1low monocyte subset impacts insulin sensitivity and weight gain upon high-fat diet in female mice.

Béliard S, Le Goff W, Saint-Charles F, Poupel L, Deswaerte V, Bouchareychas L, Huby T, Lesnik P.

Int J Obes (Lond). 2017 Dec;41(12):1805-1814. doi: 10.1038/ijo.2017.179. Epub 2017 Aug 3.

11.

Haplotypes on pig chromosome 3 distinguish metabolically healthy from unhealthy obese individuals.

Frederiksen SD, Karlskov-Mortensen P, Pant SD, Guerin M, Lesnik P, Jørgensen CB, Cirera S, Bruun CS, Mark T, Fredholm M.

PLoS One. 2017 Jun 1;12(6):e0178828. doi: 10.1371/journal.pone.0178828. eCollection 2017.

12.

Association of Cholesterol Efflux Capacity With Clinical Features of Metabolic Syndrome: Relevance to Atherosclerosis.

Gall J, Frisdal E, Bittar R, Le Goff W, Bruckert E, Lesnik P, Guerin M, Giral P.

J Am Heart Assoc. 2016 Nov 23;5(12). pii: e004808.

13.

αVβ3 integrin-targeted microSPECT/CT imaging of inflamed atherosclerotic plaques in mice.

Vancraeynest D, Roelants V, Bouzin C, Hanin FX, Walrand S, Bol V, Bol A, Pouleur AC, Pasquet A, Gerber B, Lesnik P, Huby T, Jamar F, Vanoverschelde JL.

EJNMMI Res. 2016 Dec;6(1):29. doi: 10.1186/s13550-016-0184-9. Epub 2016 Mar 24.

14.

Extended-Release Niacin/Laropiprant Improves Overall Efficacy of Postprandial Reverse Cholesterol Transport.

El Khoury P, Waldmann E, Huby T, Gall J, Couvert P, Lacorte JM, Chapman J, Frisdal E, Lesnik P, Parhofer KG, Le Goff W, Guerin M.

Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):285-94. doi: 10.1161/ATVBAHA.115.306834. Epub 2015 Dec 17.

PMID:
26681758
15.

Recent Patents on Hypocholesterolemic Therapeutic Strategies: An Update.

Potiron A, Gérard P, Le Roy T, Lesnik P, Maguin E, Rhimi M.

Recent Adv DNA Gene Seq. 2015;9(1):36-44. Review.

PMID:
26675942
16.

The spectrum of neutrophilic dermatoses associated with monoclonal gammopathy: Association with IgA isotype and inflammatory profile.

Szalat R, Monsel G, Le Goff W, Battistella M, Bengouffa D, Schlageter MH, Bouaziz JD, Arnulf B, Vignon M, Lesnik P, Saussine A, Malphettes M, Lazareth A, Vignon-Pennamen MD, Bagot M, Brouet JC, Fermand JP, Rybojad M, Asli B.

J Am Acad Dermatol. 2015 Nov;73(5):809-20. doi: 10.1016/j.jaad.2015.07.031. Epub 2015 Sep 11. Review.

PMID:
26365596
17.

Comparative Analyses of QTLs Influencing Obesity and Metabolic Phenotypes in Pigs and Humans.

Pant SD, Karlskov-Mortensen P, Jacobsen MJ, Cirera S, Kogelman LJ, Bruun CS, Mark T, Jørgensen CB, Grarup N, Appel EV, Galjatovic EA, Hansen T, Pedersen O, Guerin M, Huby T, Lesnik P, Meuwissen TH, Kadarmideen HN, Fredholm M.

PLoS One. 2015 Sep 8;10(9):e0137356. doi: 10.1371/journal.pone.0137356. eCollection 2015.

18.

[Terminology concerning intravenous ports].

Młynarski R, Kłosińska K, Cichostępski D, Dilling M, Domke B, Duraj M, Fenikowski D, Fuss J, Góraj E, Grudzień P, Grzegorczyk I, Grzesiak J, Hasak L, Janc J, Kąkol M, Kiluk M, Kłobukowski W, Leś J, Leśnik P, Lukasiewicz S, Małas T, Malczewska A, Mierzejewski M, Misiak M, Nicpoń J, Pyrek B, Rojek E, Siemiaszko A, Siemiaszko G, Sieracki A, Smiatacz M, Sobczyk A, Starzec W, Voloboyeva A, Zdyb A.

Wiad Lek. 2015;68(1):111-4. Polish.

PMID:
26094345
19.

Promoting macrophage survival delays progression of pre-existing atherosclerotic lesions through macrophage-derived apoE.

Bouchareychas L, Pirault J, Saint-Charles F, Deswaerte V, Le Roy T, Jessup W, Giral P, Le Goff W, Huby T, Gautier EL, Lesnik P.

Cardiovasc Res. 2015 Oct 1;108(1):111-23. doi: 10.1093/cvr/cvv177. Epub 2015 Jun 19.

PMID:
26092098
20.

Defective functionality of small, dense HDL3 subpopulations in ST segment elevation myocardial infarction: Relevance of enrichment in lysophosphatidylcholine, phosphatidic acid and serum amyloid A.

Rached F, Lhomme M, Camont L, Gomes F, Dauteuille C, Robillard P, Santos RD, Lesnik P, Serrano CV Jr, Chapman MJ, Kontush A.

Biochim Biophys Acta. 2015 Sep;1851(9):1254-61. doi: 10.1016/j.bbalip.2015.05.007. Epub 2015 May 30.

PMID:
26037829
21.

Altered lipidome and antioxidative activity of small, dense HDL in normolipidemic rheumatoid arthritis: relevance of inflammation.

Gómez Rosso L, Lhomme M, Meroño T, Sorroche P, Catoggio L, Soriano E, Saucedo C, Malah V, Dauteuille C, Boero L, Lesnik P, Robillard P, John Chapman M, Brites F, Kontush A.

Atherosclerosis. 2014 Dec;237(2):652-60. doi: 10.1016/j.atherosclerosis.2014.09.034. Epub 2014 Oct 18. Erratum in: Atherosclerosis. 2015 Jun;240(2):468.

PMID:
25463101
22.

Circulating phospholipid profiling identifies portal contribution to NASH signature in obesity.

Anjani K, Lhomme M, Sokolovska N, Poitou C, Aron-Wisnewsky J, Bouillot JL, Lesnik P, Bedossa P, Kontush A, Clement K, Dugail I, Tordjman J.

J Hepatol. 2015 Apr;62(4):905-12. doi: 10.1016/j.jhep.2014.11.002. Epub 2014 Nov 8.

PMID:
25450212
23.

Metabolic alterations, HFE gene mutations and atherogenic lipoprotein modifications in patients with primary iron overload.

Meroño T, Brites F, Dauteuille C, Lhomme M, Menafra M, Arteaga A, Castro M, Saez MS, Ballerga EG, Sorroche P, Rey J, Lesnik P, Sordá JA, Chapman MJ, Kontush A, Daruich J.

Clin Sci (Lond). 2015 May;128(9):609-18. doi: 10.1042/CS20140300.

PMID:
25442240
24.

Adipocyte ATP-binding cassette G1 promotes triglyceride storage, fat mass growth, and human obesity.

Frisdal E, Le Lay S, Hooton H, Poupel L, Olivier M, Alili R, Plengpanich W, Villard EF, Gilibert S, Lhomme M, Superville A, Miftah-Alkhair L, Chapman MJ, Dallinga-Thie GM, Venteclef N, Poitou C, Tordjman J, Lesnik P, Kontush A, Huby T, Dugail I, Clement K, Guerin M, Le Goff W.

Diabetes. 2015 Mar;64(3):840-55. doi: 10.2337/db14-0245. Epub 2014 Sep 23.

25.

Adrenocortical scavenger receptor class B type I deficiency exacerbates endotoxic shock and precipitates sepsis-induced mortality in mice.

Gilibert S, Galle-Treger L, Moreau M, Saint-Charles F, Costa S, Ballaire R, Couvert P, Carrié A, Lesnik P, Huby T.

J Immunol. 2014 Jul 15;193(2):817-26. doi: 10.4049/jimmunol.1303164. Epub 2014 Jun 16.

26.

Physiopathology of necrobiotic xanthogranuloma with monoclonal gammopathy.

Szalat R, Pirault J, Fermand JP, Carrié A, Saint-Charles F, Olivier M, Robillard P, Frisdal E, Villard EF, Cathébras P, Bruckert E, Chapman MJ, Giral P, Guerin M, Lesnik P, Le Goff W.

J Intern Med. 2014 Sep;276(3):269-84. doi: 10.1111/joim.12195. Epub 2014 Feb 10.

27.

Local apoptosis mediates clearance of macrophages from resolving inflammation in mice.

Gautier EL, Ivanov S, Lesnik P, Randolph GJ.

Blood. 2013 Oct 10;122(15):2714-22. doi: 10.1182/blood-2013-01-478206. Epub 2013 Aug 23.

28.

Pharmacological inhibition of the chemokine receptor, CX3CR1, reduces atherosclerosis in mice.

Poupel L, Boissonnas A, Hermand P, Dorgham K, Guyon E, Auvynet C, Charles FS, Lesnik P, Deterre P, Combadiere C.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2297-305. doi: 10.1161/ATVBAHA.112.300930. Epub 2013 Jul 25.

PMID:
23887641
29.

Respiratory function in pregnant women.

Hirnle L, Lysenko L, Gerber H, Lesnik P, Baranowska A, Rachwalik M, Leszczyszyn J, Strozecki L.

Adv Exp Med Biol. 2013;788:153-60. doi: 10.1007/978-94-007-6627-3_23.

PMID:
23835973
30.

Bcl-x inactivation in macrophages accelerates progression of advanced atherosclerotic lesions in Apoe(-/-) mice.

Shearn AI, Deswaerte V, Gautier EL, Saint-Charles F, Pirault J, Bouchareychas L, Rucker EB 3rd, Beliard S, Chapman J, Jessup W, Huby T, Lesnik P.

Arterioscler Thromb Vasc Biol. 2012 May;32(5):1142-9. doi: 10.1161/ATVBAHA.111.239111. Epub 2012 Mar 1.

PMID:
22383704
31.

Interleukin-6 protects human macrophages from cellular cholesterol accumulation and attenuates the proinflammatory response.

Frisdal E, Lesnik P, Olivier M, Robillard P, Chapman MJ, Huby T, Guerin M, Le Goff W.

J Biol Chem. 2011 Sep 2;286(35):30926-36. doi: 10.1074/jbc.M111.264325. Epub 2011 Jul 8.

32.

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management.

Chapman MJ, Ginsberg HN, Amarenco P, Andreotti F, Borén J, Catapano AL, Descamps OS, Fisher E, Kovanen PT, Kuivenhoven JA, Lesnik P, Masana L, Nordestgaard BG, Ray KK, Reiner Z, Taskinen MR, Tokgözoglu L, Tybjærg-Hansen A, Watts GF; European Atherosclerosis Society Consensus Panel.

Eur Heart J. 2011 Jun;32(11):1345-61. doi: 10.1093/eurheartj/ehr112. Epub 2011 Apr 29. Review.

33.

Atheroprotective reverse cholesterol transport pathway is defective in familial hypercholesterolemia.

Bellanger N, Orsoni A, Julia Z, Fournier N, Frisdal E, Duchene E, Bruckert E, Carrie A, Bonnefont-Rousselot D, Pirault J, Saint-Charles F, Chapman MJ, Lesnik P, Le Goff W, Guerin M.

Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1675-81. doi: 10.1161/ATVBAHA.111.227181. Epub 2011 Apr 28.

PMID:
21527752
34.

Cholesteryl ester transfer protein expression partially attenuates the adverse effects of SR-BI receptor deficiency on cholesterol metabolism and atherosclerosis.

El Bouhassani M, Gilibert S, Moreau M, Saint-Charles F, Tréguier M, Poti F, Chapman MJ, Le Goff W, Lesnik P, Huby T.

J Biol Chem. 2011 May 13;286(19):17227-38. doi: 10.1074/jbc.M111.220483. Epub 2011 Mar 20.

35.

7-ketocholesterol inhibits Na,K-ATPase activity by decreasing expression of its α1-subunit and membrane fluidity in human endothelial cells.

Duran MJ, Pierre SV, Lesnik P, Pieroni G, Bourdeaux M, Dignat-Georges F, Sampol J, Maixent JM.

Cell Mol Biol (Noisy-le-grand). 2010 Nov 9;56 Suppl:OL1434-41.

PMID:
21062577
36.

Lipoprotein(a) as a cardiovascular risk factor: current status.

Nordestgaard BG, Chapman MJ, Ray K, Borén J, Andreotti F, Watts GF, Ginsberg H, Amarenco P, Catapano A, Descamps OS, Fisher E, Kovanen PT, Kuivenhoven JA, Lesnik P, Masana L, Reiner Z, Taskinen MR, Tokgözoglu L, Tybjærg-Hansen A; European Atherosclerosis Society Consensus Panel.

Eur Heart J. 2010 Dec;31(23):2844-53. doi: 10.1093/eurheartj/ehq386. Epub 2010 Oct 21.

37.

Conventional dendritic cells at the crossroads between immunity and cholesterol homeostasis in atherosclerosis.

Gautier EL, Huby T, Saint-Charles F, Ouzilleau B, Pirault J, Deswaerte V, Ginhoux F, Miller ER, Witztum JL, Chapman MJ, Lesnik P.

Circulation. 2009 May 5;119(17):2367-75. doi: 10.1161/CIRCULATIONAHA.108.807537. Epub 2009 Apr 20.

PMID:
19380622
38.

Differential regulation of the human versus the mouse apolipoprotein AV gene by PPARalpha. Implications for the study of pharmaceutical modifiers of hypertriglyceridemia in mice.

Prieur X, Lesnik P, Moreau M, Rodríguez JC, Doucet C, Chapman MJ, Huby T.

Biochim Biophys Acta. 2009 Aug;1791(8):764-71. doi: 10.1016/j.bbalip.2009.03.015. Epub 2009 Apr 9.

PMID:
19362162
39.

Macrophage apoptosis exerts divergent effects on atherogenesis as a function of lesion stage.

Gautier EL, Huby T, Witztum JL, Ouzilleau B, Miller ER, Saint-Charles F, Aucouturier P, Chapman MJ, Lesnik P.

Circulation. 2009 Apr 7;119(13):1795-804. doi: 10.1161/CIRCULATIONAHA.108.806158. Epub 2009 Mar 23.

PMID:
19307478
40.

The standardized Ginkgo biloba extract Egb-761 protects vascular endothelium exposed to oxidized low density lipoproteins.

Pierre SV, Lesnik P, Moreau M, Bonello L, Droy-Lefaix MT, Sennoune S, Duran MJ, Pressley TA, Sampol J, Chapman J, Maixent JM.

Cell Mol Biol (Noisy-le-grand). 2008 Oct 26;54 Suppl:OL1032-42.

PMID:
18954552
41.

Enhanced dendritic cell survival attenuates lipopolysaccharide-induced immunosuppression and increases resistance to lethal endotoxic shock.

Gautier EL, Huby T, Saint-Charles F, Ouzilleau B, Chapman MJ, Lesnik P.

J Immunol. 2008 May 15;180(10):6941-6.

42.

Secretion of apolipoprotein E from macrophages occurs via a protein kinase A and calcium-dependent pathway along the microtubule network.

Kockx M, Guo DL, Huby T, Lesnik P, Kay J, Sabaretnam T, Jary E, Hill M, Gaus K, Chapman J, Stow JL, Jessup W, Kritharides L.

Circ Res. 2007 Sep 14;101(6):607-16. Epub 2007 Jul 27.

PMID:
17660382
43.

Enhanced immune system activation and arterial inflammation accelerates atherosclerosis in lupus-prone mice.

Gautier EL, Huby T, Ouzilleau B, Doucet C, Saint-Charles F, Gremy G, Chapman MJ, Lesnik P.

Arterioscler Thromb Vasc Biol. 2007 Jul;27(7):1625-31. Epub 2007 Apr 19.

PMID:
17446440
44.

Developmental neural networks in children performing a Categorical N-Back Task.

Ciesielski KT, Lesnik PG, Savoy RL, Grant EP, Ahlfors SP.

Neuroimage. 2006 Nov 15;33(3):980-90. Epub 2006 Sep 25.

PMID:
16997580
45.

Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues.

Huby T, Doucet C, Dachet C, Ouzilleau B, Ueda Y, Afzal V, Rubin E, Chapman MJ, Lesnik P.

J Clin Invest. 2006 Oct;116(10):2767-76. Epub 2006 Sep 7.

46.

A new dimension in the vasculoprotective function of HDL: progenitor-mediated endothelium repair.

Lesnik P, Chapman MJ.

Arterioscler Thromb Vasc Biol. 2006 May;26(5):965-7. No abstract available.

PMID:
16627821
47.

Increased MEG activation in OCD reflects a compensatory mechanism specific to the phase of a visual working memory task.

Ciesielski KT, Hämäläinen MS, Lesnik PG, Geller DA, Ahlfors SP.

Neuroimage. 2005 Feb 15;24(4):1180-91. Epub 2004 Dec 28.

PMID:
15670696
48.

Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis.

Lesnik P, Haskell CA, Charo IF.

J Clin Invest. 2003 Feb;111(3):333-40.

49.

The promoter of human tissue factor pathway inhibitor gene: identification of potential regulatory elements.

Petit L, Lesnik P, Dachet C, Hugou I, Moreau M, Chapman J, Rouis M.

Thromb Res. 1999 Sep 1;95(5):255-62.

PMID:
10515290

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