Sort by
Items per page

Send to

Choose Destination

Search results

Items: 15


Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy.

Singh B, Covelo A, Martell-Martínez H, Nanclares C, Sherman MA, Okematti E, Meints J, Teravskis PJ, Gallardo C, Savonenko AV, Benneyworth MA, Lesné SE, Liao D, Araque A, Lee MK.

Acta Neuropathol. 2019 Oct;138(4):551-574. doi: 10.1007/s00401-019-02032-w. Epub 2019 Jun 6.


Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons.

Khan SS, LaCroix M, Boyle G, Sherman MA, Brown JL, Amar F, Aldaco J, Lee MK, Bloom GS, Lesné SE.

Acta Neuropathol. 2018 Oct;136(4):589-605. doi: 10.1007/s00401-018-1886-z. Epub 2018 Jul 11.


Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis.

Chiang ACA, Fowler SW, Reddy R, Pletnikova O, Troncoso JC, Sherman MA, Lesne SE, Jankowsky JL.

Am J Pathol. 2018 Mar;188(3):739-756. doi: 10.1016/j.ajpath.2017.11.011. Epub 2017 Dec 15.


Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.

Larson ME, Greimel SJ, Amar F, LaCroix M, Boyle G, Sherman MA, Schley H, Miel C, Schneider JA, Kayed R, Benfenati F, Lee MK, Bennett DA, Lesné SE.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4648-E4657. doi: 10.1073/pnas.1704698114. Epub 2017 May 22.


The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation.

Amar F, Sherman MA, Rush T, Larson M, Boyle G, Chang L, Götz J, Buisson A, Lesné SE.

Sci Signal. 2017 May 9;10(478). pii: eaal2021. doi: 10.1126/scisignal.aal2021.


Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport.

Sherman MA, LaCroix M, Amar F, Larson ME, Forster C, Aguzzi A, Bennett DA, Ramsden M, Lesné SE.

J Neurosci. 2016 Sep 14;36(37):9647-58. doi: 10.1523/JNEUROSCI.1899-16.2016.


Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer's disease.

Alfonso SI, Callender JA, Hooli B, Antal CE, Mullin K, Sherman MA, Lesné SE, Leitges M, Newton AC, Tanzi RE, Malinow R.

Sci Signal. 2016 May 10;9(427):ra47. doi: 10.1126/scisignal.aaf6209.


Toxic oligomer species of amyloid-β in Alzheimer's disease, a timing issue.

Lesne SE.

Swiss Med Wkly. 2014 Nov 6;144:w14021. doi: 10.4414/smw.2014.14021. eCollection 2014. Review.


Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease.

Fowler SW, Chiang AC, Savjani RR, Larson ME, Sherman MA, Schuler DR, Cirrito JR, Lesné SE, Jankowsky JL.

J Neurosci. 2014 Jun 4;34(23):7871-85. doi: 10.1523/JNEUROSCI.0572-14.2014. Erratum in: J Neurosci. 2014 Dec 10;34(50):16917.


Breaking the Code of Amyloid-β Oligomers.

Lesné SE.

Int J Cell Biol. 2013;2013:950783. doi: 10.1155/2013/950783. Epub 2013 Aug 31. Review.


Brain amyloid-β oligomers in ageing and Alzheimer's disease.

Lesné SE, Sherman MA, Grant M, Kuskowski M, Schneider JA, Bennett DA, Ashe KH.

Brain. 2013 May;136(Pt 5):1383-98. doi: 10.1093/brain/awt062. Epub 2013 Apr 9.


The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease.

Larson M, Sherman MA, Amar F, Nuvolone M, Schneider JA, Bennett DA, Aguzzi A, Lesné SE.

J Neurosci. 2012 Nov 21;32(47):16857-71a. doi: 10.1523/JNEUROSCI.1858-12.2012.


Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology.

Larson ME, Sherman MA, Greimel S, Kuskowski M, Schneider JA, Bennett DA, Lesné SE.

J Neurosci. 2012 Jul 25;32(30):10253-66. doi: 10.1523/JNEUROSCI.0581-12.2012.


Soluble Aβ oligomer production and toxicity.

Larson ME, Lesné SE.

J Neurochem. 2012 Jan;120 Suppl 1:125-39. doi: 10.1111/j.1471-4159.2011.07478.x. Epub 2011 Nov 28. Review.


Detecting aβ*56 oligomers in brain tissues.

Sherman MA, Lesné SE.

Methods Mol Biol. 2011;670:45-56. doi: 10.1007/978-1-60761-744-0_4.


Supplemental Content

Loading ...
Support Center