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Items: 45

1.

Multiple myeloma exploits Jagged1 and Jagged2 to promote intrinsic and bone marrow-dependent drug resistance.

Colombo M, Garavelli S, Mazzola M, Platonova N, Giannandrea D, Colella R, Apicella L, Lancellotti M, Lesma E, Ancona S, Palano MT, Barbieri M, Taiana E, Lazzari E, Basile A, Turrini M, Pistocchi A, Neri A, Chiaramonte R.

Haematologica. 2019 Oct 3. pii: haematol.2019.221077. doi: 10.3324/haematol.2019.221077. [Epub ahead of print]

2.

Adipose-Derived Stem Cells from Fat Tissue of Breast Cancer Microenvironment Present Altered Adipogenic Differentiation Capabilities.

Rey F, Lesma E, Massihnia D, Ciusani E, Nava S, Vasco C, Al Haj G, Ghilardi G, Opocher E, Gorio A, Carelli S, Di Giulio AM.

Stem Cells Int. 2019 Aug 14;2019:1480314. doi: 10.1155/2019/1480314. eCollection 2019.

3.

Role of thoracic imaging in the management of lymphangioleiomyomatosis.

Crivelli P, Ledda RE, Terraneo S, Conti M, Imeri G, Lesma E, Di Marco F.

Respir Med. 2019 Oct;157:14-20. doi: 10.1016/j.rmed.2019.08.013. Epub 2019 Aug 22. Review.

PMID:
31470185
4.

Extracellular Vesicles Enhance Multiple Myeloma Metastatic Dissemination.

Colombo M, Giannandrea D, Lesma E, Basile A, Chiaramonte R.

Int J Mol Sci. 2019 Jul 1;20(13). pii: E3236. doi: 10.3390/ijms20133236. Review.

5.

Tuberous sclerosis complex: new insights into clinical and therapeutic approach.

Volpi A, Sala G, Lesma E, Labriola F, Righetti M, Alfano RM, Cozzolino M.

J Nephrol. 2019 Jun;32(3):355-363. doi: 10.1007/s40620-018-0547-6. Epub 2018 Nov 7. Review.

PMID:
30406604
6.

Cancer Cells Exploit Notch Signaling to Redefine a Supportive Cytokine Milieu.

Colombo M, Mirandola L, Chiriva-Internati M, Basile A, Locati M, Lesma E, Chiaramonte R, Platonova N.

Front Immunol. 2018 Aug 14;9:1823. doi: 10.3389/fimmu.2018.01823. eCollection 2018. Review.

7.

Lymphangioleiomyomatosis, multifocal micronodular pneumocyte hyperplasia, and sarcoidosis: more pathological findings in the same chest CT, or a single pathological pathway?

Di Marco F, Palumbo G, Terraneo S, Imeri G, Lesma E, Sverzellati N, Peron A, Gualandri L, Canevini MP, Centanni S.

BMC Pulm Med. 2017 Jul 28;17(1):107. doi: 10.1186/s12890-017-0447-x.

8.

Targeting Notch as a Therapeutic Approach for Human Malignancies.

Platonova N, Lesma E, Basile A, Bignotto M, Garavelli S, Palano MT, Moschini A, Neri A, Colombo M, Chiaramonte R.

Curr Pharm Des. 2017;23(1):108-134. doi: 10.2174/1381612822666161006160524. Review.

PMID:
27719637
9.

Women with TSC: Relationship between Clinical, Lung Function and Radiological Features in a Genotyped Population Investigated for Lymphangioleiomyomatosis.

Di Marco F, Terraneo S, Imeri G, Palumbo G, La Briola F, Tresoldi S, Volpi A, Gualandri L, Ghelma F, Alfano RM, Montanari E, Gorio A, Lesma E, Peron A, Canevini MP, Centanni S.

PLoS One. 2016 May 12;11(5):e0155331. doi: 10.1371/journal.pone.0155331. eCollection 2016.

10.

Role of Prolactin Receptors in Lymphangioleiomyomatosis.

Alkharusi A, Lesma E, Ancona S, Chiaramonte E, Nyström T, Gorio A, Norstedt G.

PLoS One. 2016 Jan 14;11(1):e0146653. doi: 10.1371/journal.pone.0146653. eCollection 2016.

11.

Glioblastoma multiforme in a child with tuberous sclerosis complex.

Vignoli A, Lesma E, Alfano RM, Peron A, Scornavacca GF, Massimino M, Schiavello E, Ancona S, Cerati M, Bulfamante G, Gorio A, Canevini MP.

Am J Med Genet A. 2015 Oct;167A(10):2388-93. doi: 10.1002/ajmg.a.37158. Epub 2015 May 6.

PMID:
25946256
12.

Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy.

Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, Sorino C, Ponzoni M, Bossi G, Federico V, La Rosa F, Ricciardi MR, Lesma E, De Meo PD, Castrignanò T, Petrucci MT, Pisani F, Chesi M, Bergsagel PL, Floridi A, Tonon G, Passananti C, Blandino G, Fanciulli M.

EMBO J. 2015 May 5;34(9):1214-30. doi: 10.15252/embj.201489920. Epub 2015 Mar 14.

13.

Anti-EGFR antibody reduces lung nodules by inhibition of EGFR-pathway in a model of lymphangioleiomyomatosis.

Lesma E, Chiaramonte E, Ancona S, Orpianesi E, Di Giulio AM, Gorio A.

Biomed Res Int. 2015;2015:315240. doi: 10.1155/2015/315240. Epub 2015 Jan 28.

14.

TSC2 epigenetic defect in primary LAM cells. Evidence of an anchorage-independent survival.

Lesma E, Ancona S, Sirchia SM, Orpianesi E, Grande V, Colapietro P, Chiaramonte E, Di Giulio AM, Gorio A.

J Cell Mol Med. 2014 May;18(5):766-79. doi: 10.1111/jcmm.12237. Epub 2014 Mar 7.

15.

Chromatin remodeling by rosuvastatin normalizes TSC2-/meth cell phenotype through the expression of tuberin.

Lesma E, Ancona S, Orpianesi E, Grande V, Di Giulio AM, Gorio A.

J Pharmacol Exp Ther. 2013 May;345(2):180-8. doi: 10.1124/jpet.113.203141. Epub 2013 Feb 20.

PMID:
23426956
16.

Development of a lymphangioleiomyomatosis model by endonasal administration of human TSC2-/- smooth muscle cells in mice.

Lesma E, Eloisa C, Isaia E, Grande V, Ancona S, Orpianesi E, Di Giulio AM, Gorio A.

Am J Pathol. 2012 Sep;181(3):947-60. doi: 10.1016/j.ajpath.2012.05.017. Epub 2012 Jul 4.

PMID:
22770663
17.

Acute spinal cord injury persistently reduces R/G RNA editing of AMPA receptors.

Barbon A, Fumagalli F, Caracciolo L, Madaschi L, Lesma E, Mora C, Carelli S, Slotkin TA, Racagni G, Di Giulio AM, Gorio A, Barlati S.

J Neurochem. 2010 Jul;114(2):397-407. doi: 10.1111/j.1471-4159.2010.06767.x. Epub 2010 Apr 23.

18.

Finite element shape optimization for biodegradable magnesium alloy stents.

Wu W, Petrini L, Gastaldi D, Villa T, Vedani M, Lesma E, Previtali B, Migliavacca F.

Ann Biomed Eng. 2010 Sep;38(9):2829-40. doi: 10.1007/s10439-010-0057-8. Epub 2010 May 6.

PMID:
20446037
19.

Lymphangioleiomyomatosis and TSC2-/- cells.

Darling TN, Pacheco-Rodriguez G, Gorio A, Lesma E, Walker C, Moss J.

Lymphat Res Biol. 2010 Mar;8(1):59-69. doi: 10.1089/lrb.2009.0031. Review.

20.

The methylation of the TSC2 promoter underlies the abnormal growth of TSC2 angiomyolipoma-derived smooth muscle cells.

Lesma E, Sirchia SM, Ancona S, Carelli S, Bosari S, Ghelma F, Montanari E, Di Giulio AM, Gorio A.

Am J Pathol. 2009 Jun;174(6):2150-9. doi: 10.2353/ajpath.2009.080799. Epub 2009 May 14.

21.

Anti-EGFR antibody efficiently and specifically inhibits human TSC2-/- smooth muscle cell proliferation. Possible treatment options for TSC and LAM.

Lesma E, Grande V, Ancona S, Carelli S, Di Giulio AM, Gorio A.

PLoS One. 2008;3(10):e3558. doi: 10.1371/journal.pone.0003558. Epub 2008 Oct 29.

22.

Survivin expression in tuberous sclerosis complex cells.

Carelli S, Lesma E, Paratore S, Grande V, Zadra G, Bosari S, Di Giulio AM, Gorio A.

Mol Med. 2007 Mar-Apr;13(3-4):166-77.

23.

A role for enhanced integrin and FAK expression in uremia-induced parathyroid hyperplasia.

Arcidiacono MV, Cozzolino M, Brancaccio D, Gallieni M, Lesma E, Carelli S, Gorio A, Di Giulio AM.

J Nephrol. 2007 Mar-Apr;20(2):228-33.

PMID:
17514628
24.

G protein-mediated signal transduction is affected in primary biliary cirrhosis.

Lesma E, Grande V, Di Giulio AM, Castellana P, Crosignani A, Cerri A, Gorio A.

Hepatol Res. 2006 May;35(1):45-52. Epub 2006 Mar 29.

PMID:
16567123
25.

Isolation and growth of smooth muscle-like cells derived from tuberous sclerosis complex-2 human renal angiomyolipoma: epidermal growth factor is the required growth factor.

Lesma E, Grande V, Carelli S, Brancaccio D, Canevini MP, Alfano RM, Coggi G, Di Giulio AM, Gorio A.

Am J Pathol. 2005 Oct;167(4):1093-103.

26.

Amelioration of neutrophil membrane function underlies granulocyte-colony stimulating factor action in glycogen storage disease 1b.

Lesma E, Riva E, Giovannini M, Di Giulio AM, Gorio A.

Int J Immunopathol Pharmacol. 2005 Apr-Jun;18(2):297-307.

PMID:
15888252
27.

Loss of the inactive X chromosome and replication of the active X in BRCA1-defective and wild-type breast cancer cells.

Sirchia SM, Ramoscelli L, Grati FR, Barbera F, Coradini D, Rossella F, Porta G, Lesma E, Ruggeri A, Radice P, Simoni G, Miozzo M.

Cancer Res. 2005 Mar 15;65(6):2139-46.

29.

Levels of Art2+ cells but not soluble Art2 protein correlate with expression of autoimmune diabetes in the BB rat.

Bortel R, Waite DJ, Whalen BJ, Todd D, Leif JH, Lesma E, Moss J, Mordes JP, Rossini AA, Greiner DL.

Autoimmunity. 2001 May;33(3):199-211.

PMID:
11683379
30.
31.

Glycosaminoglycans treatment increases IGF-I muscle levels and counteracts motor neuron death: A novel nonanticoagulant action.

Losa M, Vergani L, Lesma E, Rossoni G, Di Giulio AM, Vercelli A, Torsello A, Muller EE, Gorio A.

J Neurosci Res. 1999 Feb 15;55(4):496-505.

PMID:
10723059
32.

Long-term neuroprotective effects of glycosaminoglycans-IGF-I cotreatment in the motor neuron degeneration (mnd) mutant mouse.

Gorio A, Germani E, Lesma E, Rossoni G, Muller EE, Di Giulio AM.

Eur J Neurosci. 1999 Oct;11(10):3395-404.

PMID:
10564347
33.

Glycosaminoglycans boost insulin-like growth factor-I-promoted neuroprotection: blockade of motor neuron death in the wobbler mouse.

Vergani L, Losa M, Lesma E, Di Giulio AM, Torsello A, Müller EE, Gorio A.

Neuroscience. 1999;93(2):565-72.

PMID:
10465440
34.
36.

Characterization of NAD:arginine ADP-ribosyltransferases.

Moss J, Balducci E, Cavanaugh E, Kim HJ, Konczalik P, Lesma EA, Okazaki IJ, Park M, Shoemaker M, Stevens LA, Zolkiewska A.

Mol Cell Biochem. 1999 Mar;193(1-2):109-13. Review.

PMID:
10331646
37.

Characterization of high density lipoprotein-bound and soluble RT6 released following administration of anti-RT6.1 monoclonal antibody.

Lesma E, Moss J, Brewer HB, Bortell R, Greiner D, Mordes J, Rossini AA.

J Immunol. 1998 Aug 1;161(3):1212-9.

38.

Neuroprotection, neuroregeneration, and interaction with insulin-like growth factor-I: novel non-anticoagulant action of glycosaminoglycans.

Gorio A, Vergani L, Lesma E, Di Giulio AM.

J Neurosci Res. 1998 Mar 1;51(5):559-62. Review.

PMID:
9511999
39.

Glycosaminoglycan supplementation promotes nerve regeneration and muscle reinnervation.

Gorio A, Lesma E, Vergani L, Di Giulio AM.

Eur J Neurosci. 1997 Aug;9(8):1748-53.

PMID:
9283829
40.

Glycosaminoglycans in nerve injury: 1. Low doses of glycosaminoglycans promote neurite formation.

Lesma E, Di Giulio AM, Ferro L, Prino G, Gorio A.

J Neurosci Res. 1996 Dec 1;46(5):565-71.

PMID:
8951668
41.

Molecular characterization of a glycosylphosphatidylinositol-linked ADP-ribosyltransferase from lymphocytes.

Okazaki IJ, Kim HJ, McElvaney NG, Lesma E, Moss J.

Blood. 1996 Aug 1;88(3):915-21.

PMID:
8704249
42.

High opioid doses inhibit whereas low doses enhance neuritogenesis in PC12 cells.

Tenconi B, Lesma E, DiGiulio AM, Gorio A.

Brain Res Dev Brain Res. 1996 Jul 20;94(2):175-81.

PMID:
8836576
43.

Perinatal exposure to morphine: reactive changes in the brain after 6-hydroxydopamine.

Gorio A, Vergani L, Malosio ML, Lesma E, Di Giulio AM.

Eur J Pharmacol. 1996 May 6;303(1-2):21-6.

PMID:
8804907
44.

Perinatal morphine II: changes in cortical plasticity.

Germani E, Lesma E, De Biasi S, Di Giulio AM, Bertelli A, Gorio A.

J Neurosci Res. 1995 Dec 15;42(6):829-34.

PMID:
8847744
45.

Diabetic neuropathy in the rat: 1. Alcar augments the reduced levels and axoplasmic transport of substance P.

Di Giulio AM, Lesma E, Gorio A.

J Neurosci Res. 1995 Feb 15;40(3):414-9.

PMID:
7538169

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