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Items: 31


Interferon Beta Contributes to Astrocyte Activation in the Brain following Reovirus Infection.

Clarke P, Zhuang Y, Berens HM, Leser JS, Tyler KL.

J Virol. 2019 May 1;93(10). pii: e02027-18. doi: 10.1128/JVI.02027-18. Print 2019 May 15.


Connexin43 regulates osteoprotegerin expression via ERK1/2 -dependent recruitment of Sp1.

Gupta A, Leser JM, Gould NR, Buo AM, Moorer MC, Stains JP.

Biochem Biophys Res Commun. 2019 Feb 12;509(3):728-733. doi: 10.1016/j.bbrc.2018.12.173. Epub 2019 Jan 7.


Homotransfer of FRET Reporters for Live Cell Imaging.

Snell NE, Rao VP, Seckinger KM, Liang J, Leser J, Mancini AE, Rizzo MA.

Biosensors (Basel). 2018 Oct 11;8(4). pii: E89. doi: 10.3390/bios8040089. Review.


Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis.

Kulkarni S, Micci MA, Leser J, Shin C, Tang SC, Fu YY, Liu L, Li Q, Saha M, Li C, Enikolopov G, Becker L, Rakhilin N, Anderson M, Shen X, Dong X, Butte MJ, Song H, Southard-Smith EM, Kapur RP, Bogunovic M, Pasricha PJ.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):E3709-E3718. doi: 10.1073/pnas.1619406114. Epub 2017 Apr 18.


A mouse model of paralytic myelitis caused by enterovirus D68.

Hixon AM, Yu G, Leser JS, Yagi S, Clarke P, Chiu CY, Tyler KL.

PLoS Pathog. 2017 Feb 23;13(2):e1006199. doi: 10.1371/journal.ppat.1006199. eCollection 2017 Feb.


Mitochondrial p53 Contributes to Reovirus-Induced Neuronal Apoptosis and Central Nervous System Injury in a Mouse Model of Viral Encephalitis.

Zhuang Y, Berens-Norman HM, Leser JS, Clarke P, Tyler KL.

J Virol. 2016 Aug 12;90(17):7684-91. doi: 10.1128/JVI.00583-16. Print 2016 Sep 1.


Activation of intrinsic immune responses and microglial phagocytosis in an ex vivo spinal cord slice culture model of West Nile virus infection.

Quick ED, Leser JS, Clarke P, Tyler KL.

J Virol. 2014 Nov;88(22):13005-14. doi: 10.1128/JVI.01994-14. Epub 2014 Aug 27.


Death receptor-mediated apoptotic signaling is activated in the brain following infection with West Nile virus in the absence of a peripheral immune response.

Clarke P, Leser JS, Quick ED, Dionne KR, Beckham JD, Tyler KL.

J Virol. 2014 Jan;88(2):1080-9. doi: 10.1128/JVI.02944-13. Epub 2013 Nov 6.


Daxx upregulation within the cytoplasm of reovirus-infected cells is mediated by interferon and contributes to apoptosis.

Dionne KR, Zhuang Y, Leser JS, Tyler KL, Clarke P.

J Virol. 2013 Mar;87(6):3447-60. doi: 10.1128/JVI.02324-12. Epub 2013 Jan 9.


A brain slice culture model of viral encephalitis reveals an innate CNS cytokine response profile and the therapeutic potential of caspase inhibition.

Dionne KR, Leser JS, Lorenzen KA, Beckham JD, Tyler KL.

Exp Neurol. 2011 Apr;228(2):222-31. doi: 10.1016/j.expneurol.2011.01.006. Epub 2011 Jan 15.


Critical role for death-receptor mediated apoptotic signaling in viral myocarditis.

DeBiasi RL, Robinson BA, Leser JS, Brown RD, Long CS, Clarke P.

J Card Fail. 2010 Nov;16(11):901-10. doi: 10.1016/j.cardfail.2010.05.030.


Gene expression in the brain during reovirus encephalitis.

Tyler KL, Leser JS, Phang TL, Clarke P.

J Neurovirol. 2010 Feb;16(1):56-71. doi: 10.3109/13550280903586394.


Fas-mediated apoptotic signaling in the mouse brain following reovirus infection.

Clarke P, Beckham JD, Leser JS, Hoyt CC, Tyler KL.

J Virol. 2009 Jun;83(12):6161-70. doi: 10.1128/JVI.02488-08. Epub 2009 Mar 25.


Effect of a Terminated Cover Crop and Aldicarb on Cotton Yield and Meloidogyne incognita Population Density.

Wheeler TA, Leser JF, Keeling JW, Mullinix B.

J Nematol. 2008 Jun;40(2):147-51.


The tyrosine kinase Yes regulates actin structure and secretion during pancreatic acinar cell damage in rats.

Lynch G, Kohler S, Leser J, Beil M, Garcia-Marin LJ, Lutz MP.

Pflugers Arch. 2004 Jan;447(4):445-51. Epub 2003 Nov 21.


Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence.

Tracy S, Drescher KM, Chapman NM, Kim KS, Carson SD, Pirruccello S, Lane PH, Romero JR, Leser JS.

J Virol. 2002 Dec;76(23):12097-111.


Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells.

Piiper A, Dikic I, Lutz MP, Leser J, Kronenberger B, Elez R, Cramer H, Müller-Esterl W, Zeuzem S.

J Biol Chem. 2002 Nov 15;277(46):43623-30. Epub 2002 Sep 5.


Caspase 8-mediated cleavage of plectin precedes F-actin breakdown in acinar cells during pancreatitis.

Beil M, Leser J, Lutz MP, Gukovskaya A, Seufferlein T, Lynch G, Pandol SJ, Adler G.

Am J Physiol Gastrointest Liver Physiol. 2002 Mar;282(3):G450-60.


Supramaximal cholecystokinin displaces Munc18c from the pancreatic acinar basal surface, redirecting apical exocytosis to the basal membrane.

Gaisano HY, Lutz MP, Leser J, Sheu L, Lynch G, Tang L, Tamori Y, Trimble WS, Salapatek AM.

J Clin Invest. 2001 Dec;108(11):1597-611.


Subcellular distribution and function of Rab3A-D in pancreatic acinar AR42J cells.

Piiper A, Leser J, Lutz MP, Beil M, Zeuzem S.

Biochem Biophys Res Commun. 2001 Sep 28;287(3):746-51.


A group B coxsackievirus/poliovirus 5' nontranslated region chimera can act as an attenuated vaccine strain in mice.

Chapman NM, Ragland A, Leser JS, Höfling K, Willian S, Semler BL, Tracy S.

J Virol. 2000 May;74(9):4047-56.


Coxsackievirus expression of the murine secretory protein interleukin-4 induces increased synthesis of immunoglobulin G1 in mice.

Chapman NM, Kim KS, Tracy S, Jackson J, Höfling K, Leser JS, Malone J, Kolbeck P.

J Virol. 2000 Sep;74(17):7952-62.


Progress toward vaccines against viruses that cause heart disease.

Höfling K, Kim KS, Leser JS, Chapman NM, Willian S, Gauntt CJ, Tracy S.

Herz. 2000 May;25(3):286-90. Review.


Regulation of adherens junction protein p120(ctn) by 10 nM CCK precedes actin breakdown in rat pancreatic acini.

Leser J, Beil MF, Musa OA, Adler G, Lutz MP.

Am J Physiol Gastrointest Liver Physiol. 2000 Mar;278(3):G486-91.


Cholecystokinin-induced redistribution of paxillin in rat pancreatic acinar cells.

Leser J, Lührs H, Beil MF, Adler G, Lutz MP.

Biochem Biophys Res Commun. 1999 Jan 19;254(2):400-5.


4-Hydroxy-2-pyrone formation by chalcone and stilbene synthase with nonphysiological substrates.

Zuurbier KW, Leser J, Berger T, Hofte AJ, Schröder G, Verpoorte R, Schröder J.

Phytochemistry. 1998 Dec;49(7):1945-51.


Dissociation and reassembly of adherens junctions during experimental acute pancreatitis.

Lerch MM, Lutz MP, Weidenbach H, Müller-Pillasch F, Gress TM, Leser J, Adler G.

Gastroenterology. 1997 Oct;113(4):1355-66.


Sequencing and analysis of four new Enterobacter ampD Alleles.

Ehrhardt AF, Sanders CC, Romero JR, Leser JS.

Antimicrob Agents Chemother. 1996 Aug;40(8):1953-6.


[The role of a mediator object in the initial analytic therapy of psychotics].

Haumonte MT, Hoffmann E, Koriche A, Vallindra C, Gaume JY, Leser J.

Ann Med Psychol (Paris). 1986 Jun;144(6):669-73. French. No abstract available.


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