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Items: 1 to 50 of 53

1.

Cenerimod, a novel selective S1P1 receptor modulator with unique signaling properties.

Piali L, Birker-Robaczewska M, Lescop C, Froidevaux S, Schmitz N, Morrison K, Kohl C, Rey M, Studer R, Vezzali E, Hess P, Clozel M, Steiner B, Bolli MH, Nayler O.

Pharmacol Res Perspect. 2017 Dec;5(6). doi: 10.1002/prp2.370.

2.

S1P1 Modulator-Induced G αi Signaling and β-Arrestin Recruitment Are Both Necessary to Induce Rapid and Efficient Reduction of Blood Lymphocyte Count In Vivo.

Birker-Robaczewska M, Bolli M, Rey M, de Kanter R, Kohl C, Lescop C, Boucher M, Poirey S, Steiner B, Nayler O.

Mol Pharmacol. 2018 Feb;93(2):109-118. doi: 10.1124/mol.117.109140. Epub 2017 Dec 4.

PMID:
29203519
3.

Can Coordination-Driven Supramolecular Self-Assembly Reactions Be Conducted from Fully Aliphatic Linkers?

Elsayed Moussa M, Evariste S, Krämer B, Réau R, Scheer M, Lescop C.

Angew Chem Int Ed Engl. 2018 Jan 15;57(3):795-799. doi: 10.1002/anie.201709119. Epub 2017 Dec 12.

4.

Hexalanthanide Complexes as Molecular Precursors: Synthesis, Crystal Structure, and Luminescent and Magnetic Properties.

Yao H, Calvez G, Daiguebonne C, Bernot K, Suffren Y, Puget M, Lescop C, Guillou O.

Inorg Chem. 2017 Dec 4;56(23):14632-14642. doi: 10.1021/acs.inorgchem.7b02452. Epub 2017 Nov 10.

PMID:
29125752
6.

Coordination-Driven Syntheses of Compact Supramolecular Metallacycles toward Extended Metallo-organic Stacked Supramolecular Assemblies.

Lescop C.

Acc Chem Res. 2017 Apr 18;50(4):885-894. doi: 10.1021/acs.accounts.6b00624. Epub 2017 Mar 6.

7.

A solid state highly emissive Cu(i) metallacycle: promotion of cuprophilic interactions at the excited states.

El Sayed Moussa M, Evariste S, Wong HL, Le Bras L, Roiland C, Le Polles L, Le Guennic B, Costuas K, Yam VW, Lescop C.

Chem Commun (Camb). 2016 Sep 15;52(76):11370-11373.

PMID:
27711321
8.

Novel S1P1 receptor agonists - Part 4: Alkylaminomethyl substituted aryl head groups.

Lescop C, Müller C, Mathys B, Birker M, de Kanter R, Kohl C, Hess P, Nayler O, Rey M, Sieber P, Steiner B, Weller T, Bolli MH.

Eur J Med Chem. 2016 Jun 30;116:222-238. doi: 10.1016/j.ejmech.2016.03.048. Epub 2016 Mar 23.

PMID:
27061986
9.

Novel S1P1 receptor agonists - Part 5: From amino-to alkoxy-pyridines.

Bolli MH, Lescop C, Birker M, de Kanter R, Hess P, Kohl C, Nayler O, Rey M, Sieber P, Velker J, Weller T, Steiner B.

Eur J Med Chem. 2016 Jun 10;115:326-41. doi: 10.1016/j.ejmech.2016.03.020. Epub 2016 Mar 12.

PMID:
27027817
10.

Bimetallic Gold(I) Complexes with Ethynyl-Helicene and Bis-Phosphole Ligands: Understanding the Role of Aurophilic Interactions in their Chiroptical Properties.

El Sayed Moussa M, Chen H, Wang Z, Srebro-Hooper M, Vanthuyne N, Chevance S, Roussel C, Williams JA, Autschbach J, Réau R, Duan Z, Lescop C, Crassous J.

Chemistry. 2016 Apr 18;22(17):6075-86. doi: 10.1002/chem.201600126. Epub 2016 Mar 23.

PMID:
27004565
11.

Self-Assembly of Reactive Linear Cu3 Building Blocks for Supramolecular Coordination Chemistry and Their Reactivity toward E(n) Ligand Complexes.

Fleischmann M, Dütsch L, Elsayed Moussa M, Balázs G, Kremer W, Lescop C, Scheer M.

Inorg Chem. 2016 Mar 21;55(6):2840-54. doi: 10.1021/acs.inorgchem.5b02641. Epub 2016 Mar 3.

PMID:
26950219
12.

Correction: Supramolecular metallacycles with a 'pseudo double-paracyclophane' structure based on flexible π-conjugated linkers.

Shen W, El Sayed Moussa M, Yao Y, Réau R, Lescop C.

Chem Commun (Camb). 2015 Oct 18;51(81):15079. doi: 10.1039/c5cc90410b.

PMID:
26376949
13.

Supramolecular metallacycles with a 'pseudo double-paracyclophane' structure based on flexible π-conjugated linkers.

Shen W, El Sayed Moussa M, Yao Y, Réau R, Lescop C.

Chem Commun (Camb). 2015 Jul 25;51(58):11560-3. doi: 10.1039/c5cc03778f. Epub 2015 Jun 10. Erratum in: Chem Commun (Camb). 2015 Oct 18;51(81):15079. Réau, Regis [added].

PMID:
26060850
14.

Organometallic polyphosphorus and -arsenic ligands as linkers between pre-assembled linear Cu(I) fragments.

Fleischmann M, Dütsch L, Moussa ME, Schindler A, Balázs G, Lescop C, Scheer M.

Chem Commun (Camb). 2015 Feb 18;51(14):2893-5. doi: 10.1039/c4cc09845e.

PMID:
25582612
15.

Dissymmetrical U-shaped π-stacked supramolecular assemblies by using a dinuclear Cu(I) clip with organophosphorus ligands and monotopic fully π-conjugated ligands.

El Sayed Moussa M, Guillois K, Shen W, Réau R, Crassous J, Lescop C.

Chemistry. 2014 Nov 3;20(45):14853-67. doi: 10.1002/chem.201403758. Epub 2014 Sep 18.

16.

Phosphorus centers of different hybridization in phosphaalkene-substituted phospholes.

Öberg E, Orthaber A, Lescop C, Réau R, Hissler M, Ott S.

Chemistry. 2014 Jul 1;20(27):8421-32. doi: 10.1002/chem.201402406. Epub 2014 May 30.

17.

Novel S1P(1) receptor agonists--part 3: from thiophenes to pyridines.

Bolli MH, Abele S, Birker M, Bravo R, Bur D, de Kanter R, Kohl C, Grimont J, Hess P, Lescop C, Mathys B, Müller C, Nayler O, Rey M, Scherz M, Schmidt G, Seifert J, Steiner B, Velker J, Weller T.

J Med Chem. 2014 Jan 9;57(1):110-30. doi: 10.1021/jm4014696. Epub 2013 Dec 24.

PMID:
24367923
18.

A tetradentate metalloligand: synthesis and coordination behaviour of a 2-pyridyl-substituted cyclobutadiene iron complex.

Rezaei Rad B, Herrmann D, Lescop C, Wolf R.

Dalton Trans. 2014 Mar 21;43(11):4247-50. doi: 10.1039/c3dt52699b.

PMID:
24302434
19.

Chiroptical properties of carbo[6]helicene derivatives bearing extended π-conjugated cyano substituents.

Moussa Mel S, Srebro M, Anger E, Vanthuyne N, Roussel C, Lescop C, Autschbach J, Crassous J.

Chirality. 2013 Aug;25(8):455-65. doi: 10.1002/chir.22201.

20.

Syntheses of Cu(I) polymetallic assemblies from reaction of ligands bearing the 2,5-bis(2-pyridyl)phosphole fragment with Cu(II) precursors.

El Sayed Moussa M, Friess F, Shen W, Hissler M, Réau R, Lescop C.

Chem Commun (Camb). 2013 Jul 14;49(55):6158-60. doi: 10.1039/c3cc42955e.

PMID:
23728359
21.

Synthesis of small tetranuclear Cu(I) metallacycles based on bridging pseudohalogenide ions.

Vreshch V, Nohra B, Lescop C, Réau R.

Inorg Chem. 2013 Feb 4;52(3):1496-503. doi: 10.1021/ic3022535. Epub 2013 Jan 14.

PMID:
23317017
22.

Assembly of helicene-capped N,P,N,P,N-helicands within Cu(I) helicates: impacting chiroptical properties by ligand-ligand charge transfer.

Vreshch V, El Sayed Moussa M, Nohra B, Srebro M, Vanthuyne N, Roussel C, Autschbach J, Crassous J, Lescop C, Réau R.

Angew Chem Int Ed Engl. 2013 Feb 11;52(7):1968-72. doi: 10.1002/anie.201207251. Epub 2013 Jan 10. No abstract available.

PMID:
23307429
23.

Rhenium complexes bearing phosphole-pyridine chelates: simple molecules with large chiroptical properties.

Takacs E, Escande A, Vanthuyne N, Roussel C, Lescop C, Guinard E, Latouche C, Boucekkine A, Crassous J, Réau R, Hissler M.

Chem Commun (Camb). 2012 Jul 7;48(53):6705-7. doi: 10.1039/c2cc32542j. Epub 2012 May 24.

PMID:
22627786
24.

Dibenzophosphapentaphenes: exploiting P chemistry for gap fine-tuning and coordination-driven assembly of planar polycyclic aromatic hydrocarbons.

Bouit PA, Escande A, Szűcs R, Szieberth D, Lescop C, Nyulászi L, Hissler M, Réau R.

J Am Chem Soc. 2012 Apr 18;134(15):6524-7. doi: 10.1021/ja300171y. Epub 2012 Apr 9.

25.

Aurophilicity versus mercurophilicity: impact of d10-d10 metallophilic interactions on the structure of metal-rich supramolecular assemblies.

Vreshch V, Shen W, Nohra B, Yip SK, Yam VW, Lescop C, Réau R.

Chemistry. 2012 Jan 9;18(2):466-77. doi: 10.1002/chem.201102389. Epub 2011 Dec 6.

PMID:
22147678
26.

2,2'-Biphospholes: building blocks for tuning the HOMO-LUMO gap of π-systems using covalent bonding and metal coordination.

Chen H, Delaunay W, Yu L, Joly D, Wang Z, Li J, Wang Z, Lescop C, Tondelier D, Geffroy B, Duan Z, Hissler M, Mathey F, Réau R.

Angew Chem Int Ed Engl. 2012 Jan 2;51(1):214-7. doi: 10.1002/anie.201105924. Epub 2011 Nov 14. No abstract available.

PMID:
22083902
27.

Palladium-catalyzed regioselective C-S bond cleavage of thiophenes.

Huang H, Li J, Lescop C, Duan Z.

Org Lett. 2011 Oct 7;13(19):5252-5. doi: 10.1021/ol2021302. Epub 2011 Sep 2.

PMID:
21888338
28.

Simultaneous end-on/side-on coordination modes of a diphosphorus tetrahedral complex imposed by pre-organization of oligometallic Cu(I) acceptors.

Welsch S, Lescop C, Balazs G, Réau R, Scheer M.

Chemistry. 2011 Aug 8;17(33):9130-41. doi: 10.1002/chem.201100845. Epub 2011 Jul 1.

PMID:
21726010
29.

Folding of a supramolecular framework based on a tetrametallic clip driven by π-π interactions.

Agou T, Sébastian M, Lescop C, Réau R.

Inorg Chem. 2011 Apr 18;50(8):3183-5. doi: 10.1021/ic200268c. Epub 2011 Mar 16.

PMID:
21410214
30.

Synthetic sphingosine 1-phosphate receptor modulators--opportunities and potential pitfalls.

Bolli MH, Lescop C, Nayler O.

Curr Top Med Chem. 2011;11(6):726-57. Review.

PMID:
21261590
31.

Chiral and extended π-conjugated bis(2-pyridyl)phospholes as assembling N,P,N pincers for coordination-driven synthesis of supramolecular [2,2]paracyclophane analogues.

Aranda Perez AI, Biet T, Graule S, Agou T, Lescop C, Branda NR, Crassous J, Réau R.

Chemistry. 2011 Jan 24;17(4):1337-51. doi: 10.1002/chem.201001862. Epub 2010 Dec 7.

PMID:
21243702
32.

3,4-Dithiaphosphole and 3,3',4,4'-tetrathia-1,1'-biphosphole π-conjugated systems: S makes the impact.

Fadhel O, Benkö Z, Gras M, Deborde V, Joly D, Lescop C, Nyulászi L, Hissler M, Réau R.

Chemistry. 2010 Oct 4;16(37):11340-56. doi: 10.1002/chem.201001463.

PMID:
20715213
33.

Coordination-driven hierarchical organization of pi-conjugated systems: from molecular to supramolecular pi-stacked assemblies.

Yao Y, Shen W, Nohra B, Lescop C, Réau R.

Chemistry. 2010 Jun 25;16(24):7143-63. doi: 10.1002/chem.201000621.

PMID:
20533464
34.

Assembly of pi-conjugated phosphole azahelicene derivatives into chiral coordination complexes: an experimental and theoretical study.

Graule S, Rudolph M, Shen W, Williams JA, Lescop C, Autschbach J, Crassous J, Réau R.

Chemistry. 2010 May 25;16(20):5976-6005. doi: 10.1002/chem.200903234.

PMID:
20397244
35.

Metallahelicenes: easily accessible helicene derivatives with large and tunable chiroptical properties.

Norel L, Rudolph M, Vanthuyne N, Williams JA, Lescop C, Roussel C, Autschbach J, Crassous J, Réau R.

Angew Chem Int Ed Engl. 2010;49(1):99-102. doi: 10.1002/anie.200905099. No abstract available.

PMID:
19950158
36.

Mono-, di- and polymetallic TlI complexes stabilized by a 2,5-bis(2-pyridyl)-1-phenyl-phosphole ligand.

Welsch S, Lescop C, Réau R, Scheer M.

Dalton Trans. 2009 Apr 21;(15):2683-6. doi: 10.1039/b822721g. Epub 2009 Feb 25.

PMID:
19333491
37.

Chemistry of bridging phosphanes: a comparative study within Cu(I)-Ag(I)-Au(I) triad-based homonuclear dimers.

Welsch S, Nohra B, Peresypkina EV, Lescop C, Scheer M, Réau R.

Chemistry. 2009;15(18):4685-703. doi: 10.1002/chem.200802115.

PMID:
19326373
38.

Synthesis, electronic properties, and reactivity of phospholes and 1,1'-biphospholes bearing 2- or 3-thienyl C-substituents.

Fadhel O, Szieberth D, Deborde V, Lescop C, Nyulászi L, Hissler M, Réau R.

Chemistry. 2009;15(19):4914-24. doi: 10.1002/chem.200802677.

PMID:
19301337
39.

Engineering new metal-organic frameworks built from flexible tetrapyridines coordinated to Cu(II) and Cu(I).

Ryan PE, Lescop C, Laliberté D, Hamilton T, Maris T, Wuest JD.

Inorg Chem. 2009 Apr 6;48(7):2793-807. doi: 10.1021/ic8019809.

PMID:
19271763
40.

Ag(I) bimetallic molecular clips with adaptive coordination behavior for supramolecular chemistry.

Welsch S, Lescop C, Scheer M, Réau R.

Inorg Chem. 2008 Oct 6;47(19):8592-4. doi: 10.1021/ic801222j. Epub 2008 Aug 29.

PMID:
18754660
41.

Effect of calpain and proteasome inhibition on Ca2+-dependent proteolysis and muscle histopathology in the mdx mouse.

Briguet A, Erb M, Courdier-Fruh I, Barzaghi P, Santos G, Herzner H, Lescop C, Siendt H, Henneboehle M, Weyermann P, Magyar JP, Dubach-Powell J, Metz G, Meier T.

FASEB J. 2008 Dec;22(12):4190-200. doi: 10.1096/fj.07-099036. Epub 2008 Aug 26.

PMID:
18728218
42.

Chemistry of bridging phosphanes: CuI dimers bearing 2,5-bis(2-pyridyl)phosphole ligands.

Nohra B, Rodriguez-Sanz E, Lescop C, Réau R.

Chemistry. 2008;14(11):3391-403. doi: 10.1002/chem.200701423.

PMID:
18275066
43.

Stereoselective coordination of ditopic phospholyl-azahelicenes: a novel approach towards structural diversity in chiral pi-conjugated assemblies.

Shen W, Graule S, Crassous J, Lescop C, Gornitzka H, Réau R.

Chem Commun (Camb). 2008 Feb 21;(7):850-2. doi: 10.1039/b714340k. Epub 2007 Dec 18.

PMID:
18253525
44.

Coordination polymers with pi-stacked metalloparacyclophane motifs: F-shaped mixed-coordination dinuclear connectors.

Nohra B, Yao Y, Lescop C, Réau R.

Angew Chem Int Ed Engl. 2007;46(43):8242-5. No abstract available.

PMID:
17886821
45.
46.

An aromatic-antiaromatic switch in P-heteroles. A small change in delocalisation makes a big reactivity difference.

Nyulászi L, Hollóczki O, Lescop C, Hissler M, Réau R.

Org Biomol Chem. 2006 Mar 21;4(6):996-8. Epub 2006 Feb 10.

PMID:
16525541
47.

Novel cell-penetrating alpha-keto-amide calpain inhibitors as potential treatment for muscular dystrophy.

Lescop C, Herzner H, Siendt H, Bolliger R, Henneböhle M, Weyermann P, Briguet A, Courdier-Fruh I, Erb M, Foster M, Meier T, Magyar JP, von Sprecher A.

Bioorg Med Chem Lett. 2005 Dec 1;15(23):5176-81. Epub 2005 Sep 26.

PMID:
16185867
48.

Bridging phosphanes: exotic or versatile binucleating ligands?

Leca F, Lescop C, Rodriguez-Sanz E, Costuas K, Halet JF, Réau R.

Angew Chem Int Ed Engl. 2005 Jul 11;44(28):4362-5. No abstract available.

PMID:
15942961

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