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Items: 1 to 50 of 603

1.

Cumulative Dopamine Genetic Score predicts behavioral and electrophysiological correlates of response inhibition via interactions with task demand.

Enge S, Sach M, Reif A, Lesch KP, Miller R, Fleischhauer M.

Cogn Affect Behav Neurosci. 2019 Dec 4. doi: 10.3758/s13415-019-00752-w. [Epub ahead of print]

PMID:
31802408
2.

The DNA methylome in panic disorder: a case-control and longitudinal psychotherapy-epigenetic study.

Ziegler C, Grundner-Culemann F, Schiele MA, Schlosser P, Kollert L, Mahr M, Gajewska A, Lesch KP, Deckert J, Köttgen A, Domschke K.

Transl Psychiatry. 2019 Nov 21;9(1):314. doi: 10.1038/s41398-019-0648-6.

3.

Common brain disorders are associated with heritable patterns of apparent aging of the brain.

Kaufmann T, van der Meer D, Doan NT, Schwarz E, Lund MJ, Agartz I, Alnæs D, Barch DM, Baur-Streubel R, Bertolino A, Bettella F, Beyer MK, Bøen E, Borgwardt S, Brandt CL, Buitelaar J, Celius EG, Cervenka S, Conzelmann A, Córdova-Palomera A, Dale AM, de Quervain DJF, Carlo P, Djurovic S, Dørum ES, Eisenacher S, Elvsåshagen T, Espeseth T, Fatouros-Bergman H, Flyckt L, Franke B, Frei O, Haatveit B, Håberg AK, Harbo HF, Hartman CA, Heslenfeld D, Hoekstra PJ, Høgestøl EA, Jernigan TL, Jonassen R, Jönsson EG; Karolinska Schizophrenia Project (KaSP), Kirsch P, Kłoszewska I, Kolskår KK, Landrø NI, Hellard S, Lesch KP, Lovestone S, Lundervold A, Lundervold AJ, Maglanoc LA, Malt UF, Mecocci P, Melle I, Meyer-Lindenberg A, Moberget T, Norbom LB, Nordvik JE, Nyberg L, Oosterlaan J, Papalino M, Papassotiropoulos A, Pauli P, Pergola G, Persson K, Richard G, Rokicki J, Sanders AM, Selbæk G, Shadrin AA, Smeland OB, Soininen H, Sowa P, Steen VM, Tsolaki M, Ulrichsen KM, Vellas B, Wang L, Westman E, Ziegler GC, Zink M, Andreassen OA, Westlye LT.

Nat Neurosci. 2019 Oct;22(10):1617-1623. doi: 10.1038/s41593-019-0471-7. Epub 2019 Sep 24.

PMID:
31551603
4.

Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke.

Stegner D, Hofmann S, Schuhmann MK, Kraft P, Herrmann AM, Popp S, Höhn M, Popp M, Klaus V, Post A, Kleinschnitz C, Braun A, Meuth SG, Lesch KP, Stoll G, Kraft R, Nieswandt B.

Stroke. 2019 Nov;50(11):3238-3245. doi: 10.1161/STROKEAHA.119.025357. Epub 2019 Sep 25.

PMID:
31551038
5.

Transcript Analysis of Zebrafish GLUT3 Genes, slc2a3a and slc2a3b, Define Overlapping as Well as Distinct Expression Domains in the Zebrafish (Danio rerio) Central Nervous System.

Lechermeier CG, Zimmer F, Lüffe TM, Lesch KP, Romanos M, Lillesaar C, Drepper C.

Front Mol Neurosci. 2019 Aug 27;12:199. doi: 10.3389/fnmol.2019.00199. eCollection 2019.

6.

Hypermethylation of the serotonin transporter gene promoter in panic disorder-Epigenetic imprint of comorbid depression?

Schiele MA, Kollert L, Lesch KP, Arolt V, Zwanzger P, Deckert J, Ziegler C, Domschke K.

Eur Neuropsychopharmacol. 2019 Oct;29(10):1161-1167. doi: 10.1016/j.euroneuro.2019.07.131. Epub 2019 Jul 26.

PMID:
31353282
7.

Effects of maternal separation on serotonergic systems in the dorsal and median raphe nuclei of adult male Tph2-deficient mice.

Lieb MW, Weidner M, Arnold MR, Loupy KM, Nguyen KT, Hassell JE Jr, Schnabel KS, Kern R, Day HEW, Lesch KP, Waider J, Lowry CA.

Behav Brain Res. 2019 Nov 5;373:112086. doi: 10.1016/j.bbr.2019.112086. Epub 2019 Jul 15.

PMID:
31319134
8.

Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala.

Weidner MT, Lardenoije R, Eijssen L, Mogavero F, De Groodt LPMT, Popp S, Palme R, Förstner KU, Strekalova T, Steinbusch HWM, Schmitt-Böhrer AG, Glennon JC, Waider J, van den Hove DLA, Lesch KP.

Front Neurosci. 2019 May 10;13:460. doi: 10.3389/fnins.2019.00460. eCollection 2019.

9.

KCNJ6 variants modulate reward-related brain processes and impact executive functions in attention-deficit/hyperactivity disorder.

Ziegler GC, Röser C, Renner T, Hahn T, Ehlis AC, Weber H, Dempfle A, Walitza S, Jacob C, Romanos M, Fallgatter AJ, Reif A, Lesch KP.

Am J Med Genet B Neuropsychiatr Genet. 2019 May 17. doi: 10.1002/ajmg.b.32734. [Epub ahead of print]

PMID:
31099984
10.

Serotonin Deficiency Increases Context-Dependent Fear Learning Through Modulation of Hippocampal Activity.

Waider J, Popp S, Mlinar B, Montalbano A, Bonfiglio F, Aboagye B, Thuy E, Kern R, Thiel C, Araragi N, Svirin E, Schmitt-Böhrer AG, Corradetti R, Lowry CA, Lesch KP.

Front Neurosci. 2019 Apr 24;13:245. doi: 10.3389/fnins.2019.00245. eCollection 2019.

11.

Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish.

Reuter I, Jäckels J, Kneitz S, Kuper J, Lesch KP, Lillesaar C.

Biol Open. 2019 Jun 5;8(6). pii: bio040683. doi: 10.1242/bio.040683.

12.

Brain Imaging of the Cortex in ADHD: A Coordinated Analysis of Large-Scale Clinical and Population-Based Samples.

Hoogman M, Muetzel R, Guimaraes JP, Shumskaya E, Mennes M, Zwiers MP, Jahanshad N, Sudre G, Wolfers T, Earl EA, Soliva Vila JC, Vives-Gilabert Y, Khadka S, Novotny SE, Hartman CA, Heslenfeld DJ, Schweren LJS, Ambrosino S, Oranje B, de Zeeuw P, Chaim-Avancini TM, Rosa PGP, Zanetti MV, Malpas CB, Kohls G, von Polier GG, Seitz J, Biederman J, Doyle AE, Dale AM, van Erp TGM, Epstein JN, Jernigan TL, Baur-Streubel R, Ziegler GC, Zierhut KC, Schrantee A, Høvik MF, Lundervold AJ, Kelly C, McCarthy H, Skokauskas N, O'Gorman Tuura RL, Calvo A, Lera-Miguel S, Nicolau R, Chantiluke KC, Christakou A, Vance A, Cercignani M, Gabel MC, Asherson P, Baumeister S, Brandeis D, Hohmann S, Bramati IE, Tovar-Moll F, Fallgatter AJ, Kardatzki B, Schwarz L, Anikin A, Baranov A, Gogberashvili T, Kapilushniy D, Solovieva A, El Marroun H, White T, Karkashadze G, Namazova-Baranova L, Ethofer T, Mattos P, Banaschewski T, Coghill D, Plessen KJ, Kuntsi J, Mehta MA, Paloyelis Y, Harrison NA, Bellgrove MA, Silk TJ, Cubillo AI, Rubia K, Lazaro L, Brem S, Walitza S, Frodl T, Zentis M, Castellanos FX, Yoncheva YN, Haavik J, Reneman L, Conzelmann A, Lesch KP, Pauli P, Reif A, Tamm L, Konrad K, Oberwelland Weiss E, Busatto GF, Louza MR, Durston S, Hoekstra PJ, Oosterlaan J, Stevens MC, Ramos-Quiroga JA, Vilarroya O, Fair DA, Nigg JT, Thompson PM, Buitelaar JK, Faraone SV, Shaw P, Tiemeier H, Bralten J, Franke B.

Am J Psychiatry. 2019 Jul 1;176(7):531-542. doi: 10.1176/appi.ajp.2019.18091033. Epub 2019 Apr 24.

PMID:
31014101
13.

Family-based association study on functional α-synuclein polymorphisms in attention-deficit/hyperactivity disorder.

Gerlach M, Sharma M, Romanos M, Lesch KP, Walitza S, Conzelmann HA, Krüger R, Renner TJ.

Atten Defic Hyperact Disord. 2019 Mar;11(1):107-111. doi: 10.1007/s12402-019-00286-8. Epub 2019 Mar 29.

PMID:
30927235
14.

Dissociation of impulsivity and aggression in mice deficient for the ADHD risk gene Adgrl3: Evidence for dopamine transporter dysregulation.

Mortimer N, Ganster T, O'Leary A, Popp S, Freudenberg F, Reif A, Soler Artigas M, Ribasés M, Ramos-Quiroga JA, Lesch KP, Rivero O.

Neuropharmacology. 2019 Sep 15;156:107557. doi: 10.1016/j.neuropharm.2019.02.039. Epub 2019 Mar 6.

PMID:
30849401
15.

Editorial: Can dysregulated myelination be linked to ADHD pathogenesis and persistence?

Lesch KP.

J Child Psychol Psychiatry. 2019 Mar;60(3):229-231. doi: 10.1111/jcpp.13031.

PMID:
30786021
16.

Repeated methamphetamine treatment increases spine density in the nucleus accumbens of serotonin transporter knockout mice.

Kasahara Y, Sakakibara Y, Hiratsuka T, Moriya Y, Lesch KP, Hall FS, Uhl GR, Sora I.

Neuropsychopharmacol Rep. 2019 Jun;39(2):130-133. doi: 10.1002/npr2.12049. Epub 2019 Feb 4.

17.

Brain serotonin deficiency affects female aggression.

Kästner N, Richter SH, Urbanik S, Kunert J, Waider J, Lesch KP, Kaiser S, Sachser N.

Sci Rep. 2019 Feb 4;9(1):1366. doi: 10.1038/s41598-018-37613-4.

18.

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.

Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E, Baldursson G, Belliveau R, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Churchhouse C, Dumont A, Eriksson N, Gandal M, Goldstein JI, Grasby KL, Grove J, Gudmundsson OO, Hansen CS, Hauberg ME, Hollegaard MV, Howrigan DP, Huang H, Maller JB, Martin AR, Martin NG, Moran J, Pallesen J, Palmer DS, Pedersen CB, Pedersen MG, Poterba T, Poulsen JB, Ripke S, Robinson EB, Satterstrom FK, Stefansson H, Stevens C, Turley P, Walters GB, Won H, Wright MJ; ADHD Working Group of the Psychiatric Genomics Consortium (PGC); Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium; 23andMe Research Team, Andreassen OA, Asherson P, Burton CL, Boomsma DI, Cormand B, Dalsgaard S, Franke B, Gelernter J, Geschwind D, Hakonarson H, Haavik J, Kranzler HR, Kuntsi J, Langley K, Lesch KP, Middeldorp C, Reif A, Rohde LA, Roussos P, Schachar R, Sklar P, Sonuga-Barke EJS, Sullivan PF, Thapar A, Tung JY, Waldman ID, Medland SE, Stefansson K, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Daly MJ, Faraone SV, Børglum AD, Neale BM.

Nat Genet. 2019 Jan;51(1):63-75. doi: 10.1038/s41588-018-0269-7. Epub 2018 Nov 26.

19.

The involvement of the canonical Wnt-signaling receptor LRP5 and LRP6 gene variants with ADHD and sexual dimorphism: Association study and meta-analysis.

Grünblatt E, Nemoda Z, Werling AM, Roth A, Angyal N, Tarnok Z, Thomsen H, Peters T, Hinney A, Hebebrand J, Lesch KP, Romanos M, Walitza S.

Am J Med Genet B Neuropsychiatr Genet. 2019 Sep;180(6):365-376. doi: 10.1002/ajmg.b.32695. Epub 2018 Nov 25.

20.

Relapse of drunk driving and association with traffic accidents, alcohol-related problems and biomarkers of impulsivity.

Tokko T, Eensoo D, Vaht M, Lesch KP, Reif A, Harro J.

Acta Neuropsychiatr. 2019 Apr;31(2):84-92. doi: 10.1017/neu.2018.30. Epub 2018 Nov 26.

PMID:
30472966
21.

Cross-species models of attention-deficit/hyperactivity disorder and autism spectrum disorder: lessons from CNTNAP2, ADGRL3, and PARK2.

Dalla Vecchia E, Mortimer N, Palladino VS, Kittel-Schneider S, Lesch KP, Reif A, Schenck A, Norton WHJ.

Psychiatr Genet. 2019 Feb;29(1):1-17. doi: 10.1097/YPG.0000000000000211. Review.

PMID:
30376466
22.

Improved cognition, mild anxiety-like behavior and decreased motor performance in pyridoxal phosphatase-deficient mice.

Jeanclos E, Albersen M, Ramos RJJ, Raab A, Wilhelm C, Hommers L, Lesch KP, Verhoeven-Duif NM, Gohla A.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):193-205. doi: 10.1016/j.bbadis.2018.08.018. Epub 2018 Aug 16.

23.

Functional analysis of a triplet deletion in the gene encoding the sodium glucose transporter 3, a potential risk factor for ADHD.

Schäfer N, Friedrich M, Jørgensen ME, Kollert S, Koepsell H, Wischmeyer E, Lesch KP, Geiger D, Döring F.

PLoS One. 2018 Oct 4;13(10):e0205109. doi: 10.1371/journal.pone.0205109. eCollection 2018.

24.

Live fast, die young? A review on the developmental trajectories of ADHD across the lifespan.

Franke B, Michelini G, Asherson P, Banaschewski T, Bilbow A, Buitelaar JK, Cormand B, Faraone SV, Ginsberg Y, Haavik J, Kuntsi J, Larsson H, Lesch KP, Ramos-Quiroga JA, Réthelyi JM, Ribases M, Reif A.

Eur Neuropsychopharmacol. 2018 Oct;28(10):1059-1088. doi: 10.1016/j.euroneuro.2018.08.001. Epub 2018 Sep 6. Review.

25.

Early-life stress impairs developmental programming in Cadherin 13 (CDH13)-deficient mice.

Kiser DP, Popp S, Schmitt-Böhrer AG, Strekalova T, van den Hove DL, Lesch KP, Rivero O.

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:158-168. doi: 10.1016/j.pnpbp.2018.08.010. Epub 2018 Aug 28.

26.

Differential anxiety-related behaviours and brain activation in Tph2-deficient female mice exposed to adverse early environment.

Auth CS, Weidner MT, Popp S, Strekalova T, Schmitt-Böhrer AG, van den Hove D, Lesch KP, Waider J.

Eur Neuropsychopharmacol. 2018 Nov;28(11):1270-1283. doi: 10.1016/j.euroneuro.2018.07.103. Epub 2018 Aug 23.

PMID:
30146458
27.

Identification of ADHD risk genes in extended pedigrees by combining linkage analysis and whole-exome sequencing.

Corominas J, Klein M, Zayats T, Rivero O, Ziegler GC, Pauper M, Neveling K, Poelmans G, Jansch C, Svirin E, Geissler J, Weber H, Reif A, Arias Vasquez A, Galesloot TE, Kiemeney LALM, Buitelaar JK, Ramos-Quiroga JA, Cormand B, Ribasés M, Hveem K, Gabrielsen ME, Hoffmann P, Cichon S, Haavik J, Johansson S, Jacob CP, Romanos M, Franke B, Lesch KP.

Mol Psychiatry. 2018 Aug 16. doi: 10.1038/s41380-018-0210-6. [Epub ahead of print]

PMID:
30116028
28.

Analysis of shared heritability in common disorders of the brain.

Brainstorm Consortium, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze JF, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, St George-Hyslop P, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JSK, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, Nöthen MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh KH, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HHH, Lehtimäki T, Wedenoja J, Buring JE, Schürks M, Hrafnsdottir M, Hottenga JJ, Penninx B, Artto V, Kaunisto M, Vepsäläinen S, Martin NG, Montgomery GW, Kurki MI, Hämäläinen E, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, Göbel H, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart JA, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono RJ, Catarino CB, Cossette P, De Jonghe P, Depondt C, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, Kälviäinen R, Kunz WS, Lerche H, Leu C, Lindhout D, Lo W, Lowenstein D, McCormack M, Møller RS, Molloy A, Ng PW, Oliver K, Privitera M, Radtke R, Ruppert AK, Sander T, Schachter S, Schankin C, Scheffer I, Schoch S, Sisodiya SM, Smith P, Sperling M, Striano P, Surges R, Thomas GN, Visscher F, Whelan CD, Zara F, Heinzen EL, Marson A, Becker F, Stroink H, Zimprich F, Gasser T, Gibbs R, Heutink P, Martinez M, Morris HR, Sharma M, Ryten M, Mok KY, Pulit S, Bevan S, Holliday E, Attia J, Battey T, Boncoraglio G, Thijs V, Chen WM, Mitchell B, Rothwell P, Sharma P, Sudlow C, Vicente A, Markus H, Kourkoulis C, Pera J, Raffeld M, Silliman S, Boraska Perica V, Thornton LM, Huckins LM, William Rayner N, Lewis CM, Gratacos M, Rybakowski F, Keski-Rahkonen A, Raevuori A, Hudson JI, Reichborn-Kjennerud T, Monteleone P, Karwautz A, Mannik K, Baker JH, O'Toole JK, Trace SE, Davis OSP, Helder SG, Ehrlich S, Herpertz-Dahlmann B, Danner UN, van Elburg AA, Clementi M, Forzan M, Docampo E, Lissowska J, Hauser J, Tortorella A, Maj M, Gonidakis F, Tziouvas K, Papezova H, Yilmaz Z, Wagner G, Cohen-Woods S, Herms S, Julià A, Rabionet R, Dick DM, Ripatti S, Andreassen OA, Espeseth T, Lundervold AJ, Steen VM, Pinto D, Scherer SW, Aschauer H, Schosser A, Alfredsson L, Padyukov L, Halmi KA, Mitchell J, Strober M, Bergen AW, Kaye W, Szatkiewicz JP, Cormand B, Ramos-Quiroga JA, Sánchez-Mora C, Ribasés M, Casas M, Hervas A, Arranz MJ, Haavik J, Zayats T, Johansson S, Williams N, Dempfle A, Rothenberger A, Kuntsi J, Oades RD, Banaschewski T, Franke B, Buitelaar JK, Arias Vasquez A, Doyle AE, Reif A, Lesch KP, Freitag C, Rivero O, Palmason H, Romanos M, Langley K, Rietschel M, Witt SH, Dalsgaard S, Børglum AD, Waldman I, Wilmot B, Molly N, Bau CHD, Crosbie J, Schachar R, Loo SK, McGough JJ, Grevet EH, Medland SE, Robinson E, Weiss LA, Bacchelli E, Bailey A, Bal V, Battaglia A, Betancur C, Bolton P, Cantor R, Celestino-Soper P, Dawson G, De Rubeis S, Duque F, Green A, Klauck SM, Leboyer M, Levitt P, Maestrini E, Mane S, De-Luca DM, Parr J, Regan R, Reichenberg A, Sandin S, Vorstman J, Wassink T, Wijsman E, Cook E, Santangelo S, Delorme R, Rogé B, Magalhaes T, Arking D, Schulze TG, Thompson RC, Strohmaier J, Matthews K, Melle I, Morris D, Blackwood D, McIntosh A, Bergen SE, Schalling M, Jamain S, Maaser A, Fischer SB, Reinbold CS, Fullerton JM, Guzman-Parra J, Mayoral F, Schofield PR, Cichon S, Mühleisen TW, Degenhardt F, Schumacher J, Bauer M, Mitchell PB, Gershon ES, Rice J, Potash JB, Zandi PP, Craddock N, Ferrier IN, Alda M, Rouleau GA, Turecki G, Ophoff R, Pato C, Anjorin A, Stahl E, Leber M, Czerski PM, Cruceanu C, Jones IR, Posthuma D, Andlauer TFM, Forstner AJ, Streit F, Baune BT, Air T, Sinnamon G, Wray NR, MacIntyre DJ, Porteous D, Homuth G, Rivera M, Grove J, Middeldorp CM, Hickie I, Pergadia M, Mehta D, Smit JH, Jansen R, de Geus E, Dunn E, Li QS, Nauck M, Schoevers RA, Beekman AT, Knowles JA, Viktorin A, Arnold P, Barr CL, Bedoya-Berrio G, Bienvenu OJ, Brentani H, Burton C, Camarena B, Cappi C, Cath D, Cavallini M, Cusi D, Darrow S, Denys D, Derks EM, Dietrich A, Fernandez T, Figee M, Freimer N, Gerber G, Grados M, Greenberg E, Hanna GL, Hartmann A, Hirschtritt ME, Hoekstra PJ, Huang A, Huyser C, Illmann C, Jenike M, Kuperman S, Leventhal B, Lochner C, Lyon GJ, Macciardi F, Madruga-Garrido M, Malaty IA, Maras A, McGrath L, Miguel EC, Mir P, Nestadt G, Nicolini H, Okun MS, Pakstis A, Paschou P, Piacentini J, Pittenger C, Plessen K, Ramensky V, Ramos EM, Reus V, Richter MA, Riddle MA, Robertson MM, Roessner V, Rosário M, Samuels JF, Sandor P, Stein DJ, Tsetsos F, Van Nieuwerburgh F, Weatherall S, Wendland JR, Wolanczyk T, Worbe Y, Zai G, Goes FS, McLaughlin N, Nestadt PS, Grabe HJ, Depienne C, Konkashbaev A, Lanzagorta N, Valencia-Duarte A, Bramon E, Buccola N, Cahn W, Cairns M, Chong SA, Cohen D, Crespo-Facorro B, Crowley J, Davidson M, DeLisi L, Dinan T, Donohoe G, Drapeau E, Duan J, Haan L, Hougaard D, Karachanak-Yankova S, Khrunin A, Klovins J, Kučinskas V, Lee Chee Keong J, Limborska S, Loughland C, Lönnqvist J, Maher B, Mattheisen M, McDonald C, Murphy KC, Nenadic I, van Os J, Pantelis C, Pato M, Petryshen T, Quested D, Roussos P, Sanders AR, Schall U, Schwab SG, Sim K, So HC, Stögmann E, Subramaniam M, Toncheva D, Waddington J, Walters J, Weiser M, Cheng W, Cloninger R, Curtis D, Gejman PV, Henskens F, Mattingsdal M, Oh SY, Scott R, Webb B, Breen G, Churchhouse C, Bulik CM, Daly M, Dichgans M, Faraone SV, Guerreiro R, Holmans P, Kendler KS, Koeleman B, Mathews CA, Price A, Scharf J, Sklar P, Williams J, Wood NW, Cotsapas C, Palotie A, Smoller JW, Sullivan P, Rosand J, Corvin A, Neale BM, Schott JM, Anney R, Elia J, Grigoroiu-Serbanescu M, Edenberg HJ, Murray R.

Science. 2018 Jun 22;360(6395). pii: eaap8757. doi: 10.1126/science.aap8757.

29.

Genetic variation in serotonin function impacts on altruistic punishment in the ultimatum game: A longitudinal approach.

Gärtner A, Strobel A, Reif A, Lesch KP, Enge S.

Brain Cogn. 2018 Aug;125:37-44. doi: 10.1016/j.bandc.2018.05.007. Epub 2018 May 30.

PMID:
29859448
30.

Special Editorial: Open science and the Journal of Child Psychology & Psychiatry - next steps?

Asarnow J, Bloch MH, Brandeis D, Alexandra Burt S, Fearon P, Fombonne E, Green J, Gregory A, Gunnar M, Halperin JM, Hollis C, Jaffee S, Klump K, Landau S, Lesch KP, Oldehinkel AJT, Peterson B, Ramchandani P, Sonuga-Barke E, Stringaris A, Zeanah CH.

J Child Psychol Psychiatry. 2018 Jul;59(7):826-827. doi: 10.1111/jcpp.12929. Epub 2018 May 28.

PMID:
29806217
31.

Family environment interacts with CRHR1 rs17689918 to predict mental health and behavioral outcomes.

Roy A, Laas K, Kurrikoff T, Reif A, Veidebaum T, Lesch KP, Harro J.

Prog Neuropsychopharmacol Biol Psychiatry. 2018 Aug 30;86:45-51. doi: 10.1016/j.pnpbp.2018.05.004. Epub 2018 May 14.

PMID:
29772307
32.

Insulin receptor in the brain: Mechanisms of activation and the role in the CNS pathology and treatment.

Pomytkin I, Costa-Nunes JP, Kasatkin V, Veniaminova E, Demchenko A, Lyundup A, Lesch KP, Ponomarev ED, Strekalova T.

CNS Neurosci Ther. 2018 Sep;24(9):763-774. doi: 10.1111/cns.12866. Epub 2018 Apr 24. Review.

33.

Expression of the ADHD candidate gene Diras2 in the brain.

Grünewald L, Becker N, Camphausen A, O'Leary A, Lesch KP, Freudenberg F, Reif A.

J Neural Transm (Vienna). 2018 Jun;125(6):913-923. doi: 10.1007/s00702-018-1867-3. Epub 2018 Feb 27.

PMID:
29488099
34.

Generation of a human induced pluripotent stem cell (iPSC) line from a 51-year-old female with attention-deficit/hyperactivity disorder (ADHD) carrying a duplication of SLC2A3.

Jansch C, Günther K, Waider J, Ziegler GC, Forero A, Kollert S, Svirin E, Pühringer D, Kwok CK, Ullmann R, Maierhofer A, Flunkert J, Haaf T, Edenhofer F, Lesch KP.

Stem Cell Res. 2018 Apr;28:136-140. doi: 10.1016/j.scr.2018.02.005. Epub 2018 Feb 13.

35.

'Shine bright like a diamond!': is research on high-functioning ADHD at last entering the mainstream?

Lesch KP.

J Child Psychol Psychiatry. 2018 Mar;59(3):191-192. doi: 10.1111/jcpp.12887.

PMID:
29442378
36.

Increased functional coupling of 5-HT1A autoreceptors to GIRK channels in Tph2-/- mice.

Mlinar B, Montalbano A, Waider J, Lesch KP, Corradetti R.

Eur Neuropsychopharmacol. 2017 Dec;27(12):1258-1267. doi: 10.1016/j.euroneuro.2017.10.033. Epub 2017 Nov 8.

PMID:
29126768
37.

Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain.

Forero A, Rivero O, Wäldchen S, Ku HP, Kiser DP, Gärtner Y, Pennington LS, Waider J, Gaspar P, Jansch C, Edenhofer F, Resink TJ, Blum R, Sauer M, Lesch KP.

Front Cell Neurosci. 2017 Sep 26;11:307. doi: 10.3389/fncel.2017.00307. eCollection 2017.

38.

Genetically driven brain serotonin deficiency facilitates panic-like escape behavior in mice.

Waider J, Popp S, Lange MD, Kern R, Kolter JF, Kobler J, Donner NC, Lowe KR, Malzbender JH, Brazell CJ, Arnold MR, Aboagye B, Schmitt-Böhrer A, Lowry CA, Pape HC, Lesch KP.

Transl Psychiatry. 2017 Oct 3;7(10):e1246. doi: 10.1038/tp.2017.209.

39.

Serotonin augmentation therapy by escitalopram has minimal effects on amyloid-β levels in early-stage Alzheimer's-like disease in mice.

von Linstow CU, Waider J, Grebing M, Metaxas A, Lesch KP, Finsen B.

Alzheimers Res Ther. 2017 Sep 12;9(1):74. doi: 10.1186/s13195-017-0298-y.

40.

Pro-neurogenic, Memory-Enhancing and Anti-stress Effects of DF302, a Novel Fluorine Gamma-Carboline Derivative with Multi-target Mechanism of Action.

Strekalova T, Bahzenova N, Trofimov A, Schmitt-Böhrer AG, Markova N, Grigoriev V, Zamoyski V, Serkova T, Redkozubova O, Vinogradova D, Umriukhin A, Fisenko V, Lillesaar C, Shevtsova E, Sokolov V, Aksinenko A, Lesch KP, Bachurin S.

Mol Neurobiol. 2018 Jan;55(1):335-349. doi: 10.1007/s12035-017-0745-6.

PMID:
28856531
41.

Increased fear learning, spatial learning as well as neophobia in Rgs2-/- mice.

Raab A, Popp S, Lesch KP, Lohse MJ, Fischer M, Deckert J, Hommers L.

Genes Brain Behav. 2018 Apr;17(4):e12420. doi: 10.1111/gbb.12420. Epub 2017 Sep 22.

PMID:
28846187
42.

Impact of varying social experiences during life history on behaviour, gene expression, and vasopressin receptor gene methylation in mice.

Bodden C, van den Hove D, Lesch KP, Sachser N.

Sci Rep. 2017 Aug 18;7(1):8719. doi: 10.1038/s41598-017-09292-0.

43.

Elucidating the functions of brain GSK3α: Possible synergy with GSK3β upregulation and reversal by antidepressant treatment in a mouse model of depressive-like behaviour.

Pavlov D, Markova N, Bettendorff L, Chekhonin V, Pomytkin I, Lioudyno V, Svistunov A, Ponomarev E, Lesch KP, Strekalova T.

Behav Brain Res. 2017 Sep 29;335:122-127. doi: 10.1016/j.bbr.2017.08.018. Epub 2017 Aug 10.

PMID:
28803855
44.

Autism-Like Behaviours and Memory Deficits Result from a Western Diet in Mice.

Veniaminova E, Cespuglio R, Cheung CW, Umriukhin A, Markova N, Shevtsova E, Lesch KP, Anthony DC, Strekalova T.

Neural Plast. 2017;2017:9498247. doi: 10.1155/2017/9498247. Epub 2017 Jun 8.

45.

Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder.

Rutten BPF, Vermetten E, Vinkers CH, Ursini G, Daskalakis NP, Pishva E, de Nijs L, Houtepen LC, Eijssen L, Jaffe AE, Kenis G, Viechtbauer W, van den Hove D, Schraut KG, Lesch KP, Kleinman JE, Hyde TM, Weinberger DR, Schalkwyk L, Lunnon K, Mill J, Cohen H, Yehuda R, Baker DG, Maihofer AX, Nievergelt CM, Geuze E, Boks MPM.

Mol Psychiatry. 2018 May;23(5):1145-1156. doi: 10.1038/mp.2017.120. Epub 2017 Jun 20.

46.

Rsk2 Knockout Affects Emotional Behavior in the IntelliCage.

Fischer M, Cabello V, Popp S, Krackow S, Hommers L, Deckert J, Lesch KP, Schmitt-Böhrer AG.

Behav Genet. 2017 Jul;47(4):434-448. doi: 10.1007/s10519-017-9853-3. Epub 2017 Jun 6.

PMID:
28585192
47.

Postnatal LPS Challenge Impacts Escape Learning and Expression of Plasticity Factors Mmp9 and Timp1 in Rats: Effects of Repeated Training.

Trofimov A, Strekalova T, Mortimer N, Zubareva O, Schwarz A, Svirin E, Umriukhin A, Svistunov A, Lesch KP, Klimenko V.

Neurotox Res. 2017 Aug;32(2):175-186. doi: 10.1007/s12640-017-9720-2. Epub 2017 Apr 18.

48.

Effect of aging and Alzheimer's disease-like pathology on brain monoamines in mice.

Von Linstow CU, Severino M, Metaxas A, Waider J, Babcock AA, Lesch KP, Gramsbergen JB, Finsen B.

Neurochem Int. 2017 Sep;108:238-245. doi: 10.1016/j.neuint.2017.04.008. Epub 2017 Apr 13.

PMID:
28414094
49.

T-cadherin promotes autophagy and survival in vascular smooth muscle cells through MEK1/2/Erk1/2 axis activation.

Kyriakakis E, Frismantiene A, Dasen B, Pfaff D, Rivero O, Lesch KP, Erne P, Resink TJ, Philippova M.

Cell Signal. 2017 Jul;35:163-175. doi: 10.1016/j.cellsig.2017.04.004. Epub 2017 Apr 6.

PMID:
28392425
50.

SLC2A3 single-nucleotide polymorphism and duplication influence cognitive processing and population-specific risk for attention-deficit/hyperactivity disorder.

Merker S, Reif A, Ziegler GC, Weber H, Mayer U, Ehlis AC, Conzelmann A, Johansson S, Müller-Reible C, Nanda I, Haaf T, Ullmann R, Romanos M, Fallgatter AJ, Pauli P, Strekalova T, Jansch C, Vasquez AA, Haavik J, Ribasés M, Ramos-Quiroga JA, Buitelaar JK, Franke B, Lesch KP.

J Child Psychol Psychiatry. 2017 Jul;58(7):798-809. doi: 10.1111/jcpp.12702. Epub 2017 Feb 22.

PMID:
28224622

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