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Items: 32

1.

Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes.

Arenzana TL, Lianoglou S, Seki A, Eidenschenk C, Cheung T, Seshasayee D, Hagenbeek T, Sambandam A, Noubade R, Peng I, Lesch J, DeVoss J, Wu X, Lee WP, Caplazi P, Webster J, Liu J, Pham VC, Arnott D, Lill JR, Modrusan Z, Dey A, Rutz S.

Sci Immunol. 2018 Apr 20;3(22). pii: eaal1953. doi: 10.1126/sciimmunol.aal1953.

PMID:
29678836
2.

Rheumatoid Arthritis Magnetic Resonance Imaging Score Predicts Therapy Response: Results of the German ArthroMark Cohort.

Sewerin P, Le L, Vordenbäumen S, Schleich C, Sengewein R, Brinks R, Pongratz G, Bleck E, Lesch J, Mansmann U, Schneider M, Ostendorf B.

J Rheumatol. 2018 Jun;45(6):753-759. doi: 10.3899/jrheum.170797. Epub 2018 Apr 1.

PMID:
29606664
3.

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus.

Brightbill HD, Suto E, Blaquiere N, Ramamoorthi N, Sujatha-Bhaskar S, Gogol EB, Castanedo GM, Jackson BT, Kwon YC, Haller S, Lesch J, Bents K, Everett C, Kohli PB, Linge S, Christian L, Barrett K, Jaochico A, Berezhkovskiy LM, Fan PW, Modrusan Z, Veliz K, Townsend MJ, DeVoss J, Johnson AR, Godemann R, Lee WP, Austin CD, McKenzie BS, Hackney JA, Crawford JJ, Staben ST, Alaoui Ismaili MH, Wu LC, Ghilardi N.

Nat Commun. 2018 Jan 12;9(1):179. doi: 10.1038/s41467-017-02672-0.

4.

Effectiveness of Evidence-Based Asthma Interventions.

Kennedy S, Bailey R, Jaffee K, Markus A, Gerstein M, Stevens DM, Lesch JK, Malveaux FJ, Mitchell H.

Pediatrics. 2017 Jun;139(6). pii: e20164221. doi: 10.1542/peds.2016-4221. Epub 2017 May 9.

5.

Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.

Katewa A, Wang Y, Hackney JA, Huang T, Suto E, Ramamoorthi N, Austin CD, Bremer M, Chen JZ, Crawford JJ, Currie KS, Blomgren P, DeVoss J, DiPaolo JA, Hau J, Johnson A, Lesch J, DeForge LE, Lin Z, Liimatta M, Lubach JW, McVay S, Modrusan Z, Nguyen A, Poon C, Wang J, Liu L, Lee WP, Wong H, Young WB, Townsend MJ, Reif K.

JCI Insight. 2017 Apr 6;2(7):e90111. doi: 10.1172/jci.insight.90111.

6.

Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation.

Vander Lugt B, Riddell J, Khan AA, Hackney JA, Lesch J, DeVoss J, Weirauch MT, Singh H, Mellman I.

J Cell Biol. 2017 Mar 6;216(3):779-792. doi: 10.1083/jcb.201512012. Epub 2017 Jan 27.

7.

Pediatric Asthma Care Coordination in Underserved Communities: A Quasiexperimental Study.

Janevic MR, Stoll S, Wilkin M, Song PX, Baptist A, Lara M, Ramos-Valencia G, Bryant-Stephens T, Persky V, Uyeda K, Lesch JK, Wang W, Malveaux FJ.

Am J Public Health. 2016 Nov;106(11):2012-2018. Epub 2016 Sep 15.

8.

The "Retrofitting" Approach to Adapting Evidence-Based Interventions: A Case Study of Pediatric Asthma Care Coordination, United States, 2010-2014.

Janevic MR, Stoll SC, Lara M, Ramos-Valencia G, Bryant-Stephens T, Persky V, Uyeda K, Lesch JK, Malveaux FJ.

Prev Chronic Dis. 2016 Aug 25;13:E114. doi: 10.5888/pcd13.160129.

9.

NeuCode Proteomics Reveals Bap1 Regulation of Metabolism.

Baughman JM, Rose CM, Kolumam G, Webster JD, Wilkerson EM, Merrill AE, Rhoads TW, Noubade R, Katavolos P, Lesch J, Stapleton DS, Rabaglia ME, Schueler KL, Asuncion R, Domeyer M, Zavala-Solorio J, Reich M, DeVoss J, Keller MP, Attie AD, Hebert AS, Westphall MS, Coon JJ, Kirkpatrick DS, Dey A.

Cell Rep. 2016 Jul 12;16(2):583-595. doi: 10.1016/j.celrep.2016.05.096. Epub 2016 Jun 30.

10.

Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response.

Sun Y, Peng I, Webster JD, Suto E, Lesch J, Wu X, Senger K, Francis G, Barrett K, Collier JL, Burch JD, Zhou M, Chen Y, Chan C, Eastham-Anderson J, Ngu H, Li O, Staton T, Havnar C, Jaochico A, Jackman J, Jeet S, Riol-Blanco L, Wu LC, Choy DF, Arron JR, McKenzie BS, Ghilardi N, Ismaili MH, Pei Z, DeVoss J, Austin CD, Lee WP, Zarrin AA.

Sci Signal. 2015 Dec 1;8(405):ra122. doi: 10.1126/scisignal.aab0949.

PMID:
26628680
11.

Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) inverse agonist.

Fauber BP, René O, Deng Y, DeVoss J, Eidenschenk C, Everett C, Ganguli A, Gobbi A, Hawkins J, Johnson AR, La H, Lesch J, Lockey P, Norman M, Ouyang W, Summerhill S, Wong H.

J Med Chem. 2015 Jul 9;58(13):5308-22. doi: 10.1021/acs.jmedchem.5b00597. Epub 2015 Jun 23.

PMID:
26061388
12.

Image Analysis-Based Approaches for Scoring Mouse Models of Colitis.

Rogers R, Eastham-Anderson J, DeVoss J, Lesch J, Yan D, Xu M, Solon M, Hotzel K, Diehl L, Webster JD.

Vet Pathol. 2016 Jan;53(1):200-10. doi: 10.1177/0300985815579998. Epub 2015 Apr 23.

PMID:
25907770
13.

Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells.

Rutz S, Kayagaki N, Phung QT, Eidenschenk C, Noubade R, Wang X, Lesch J, Lu R, Newton K, Huang OW, Cochran AG, Vasser M, Fauber BP, DeVoss J, Webster J, Diehl L, Modrusan Z, Kirkpatrick DS, Lill JR, Ouyang W, Dixit VM.

Nature. 2015 Feb 19;518(7539):417-21. doi: 10.1038/nature13979. Epub 2014 Dec 3.

PMID:
25470037
14.

Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes.

Wang X, Ota N, Manzanillo P, Kates L, Zavala-Solorio J, Eidenschenk C, Zhang J, Lesch J, Lee WP, Ross J, Diehl L, van Bruggen N, Kolumam G, Ouyang W.

Nature. 2014 Oct 9;514(7521):237-41. doi: 10.1038/nature13564. Epub 2014 Aug 6.

PMID:
25119041
15.

PILRα negatively regulates mouse inflammatory arthritis.

Sun Y, Caplazi P, Zhang J, Mazloom A, Kummerfeld S, Quinones G, Senger K, Lesch J, Peng I, Sebrell A, Luk W, Lu Y, Lin Z, Barck K, Young J, Del Rio M, Lehar S, Asghari V, Lin W, Mariathasan S, DeVoss J, Misaghi S, Balazs M, Sai T, Haley B, Hass PE, Xu M, Ouyang W, Martin F, Lee WP, Zarrin AA.

J Immunol. 2014 Jul 15;193(2):860-70. doi: 10.4049/jimmunol.1400045. Epub 2014 Jun 16.

16.

Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation.

Vander Lugt B, Khan AA, Hackney JA, Agrawal S, Lesch J, Zhou M, Lee WP, Park S, Xu M, DeVoss J, Spooner CJ, Chalouni C, Delamarre L, Mellman I, Singh H.

Nat Immunol. 2014 Feb;15(2):161-7. doi: 10.1038/ni.2795. Epub 2013 Dec 22.

PMID:
24362890
17.

Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1.

Spooner CJ, Lesch J, Yan D, Khan AA, Abbas A, Ramirez-Carrozzi V, Zhou M, Soriano R, Eastham-Anderson J, Diehl L, Lee WP, Modrusan Z, Pappu R, Xu M, DeVoss J, Singh H.

Nat Immunol. 2013 Dec;14(12):1229-36. doi: 10.1038/ni.2743. Epub 2013 Oct 20.

PMID:
24141388
18.

An entirely automated method to score DSS-induced colitis in mice by digital image analysis of pathology slides.

Kozlowski C, Jeet S, Beyer J, Guerrero S, Lesch J, Wang X, Devoss J, Diehl L.

Dis Model Mech. 2013 May;6(3):855-65. doi: 10.1242/dmm.011759. Epub 2013 Apr 10.

19.

Translating evidence-based interventions into practice: the design and development of the Merck Childhood Asthma Network, Inc. (MCAN).

Viswanathan M, Lux L, Lohr KN, Evans TS, Smith LR, Woodell C, Mansfield C, Darcy N; MCAN Site Investigators, Ohadike YU, Lesch JK, Malveaux FJ.

Health Promot Pract. 2011 Nov;12(6 Suppl 1):9S-19S. doi: 10.1177/1524839911412594.

PMID:
22068366
20.

Challenges and lessons learned from the translation of evidence-based childhood asthma interventions: a commentary on the MCAN initiative.

Ohadike YU, Malveaux FJ, Lesch JK.

Health Promot Pract. 2011 Nov;12(6 Suppl 1):91S-9S. doi: 10.1177/1524839911414565.

PMID:
22068365
21.

Desired attributes and skills of program managers in translation of evidence-based interventions.

Williams R, Woodell C, McCarville E, Damitz M, Banks T, Montoya J, Lesch JK, Peretz P, Lara M.

Health Promot Pract. 2011 Nov;12(6 Suppl 1):82S-90S. doi: 10.1177/1524839911412593.

PMID:
22068364
22.

The role of partnerships in addressing childhood asthma: the experiences of the Merck Childhood Asthma Network, Inc. (MCAN) initiative.

Smith LR, Nerz P, Bryant-Stephens T, Damitz M, Lara M, Peretz P, Valencia GR, Uyeda K, Darcy N, Viswanathan M, Lesch JK, Malveaux FJ.

Health Promot Pract. 2011 Nov;12(6 Suppl 1):73S-81S. doi: 10.1177/1524839911415263.

PMID:
22068363
23.

Outcomes from a cross-site evaluation of a comprehensive pediatric asthma initiative incorporating translation of evidence-based interventions.

Mansfield C, Viswanathan M, Woodell C, Nourani V, Ohadike YU, Lesch JK, Malveaux FJ, Bryant-Stephens T, Findley S, Lara M, Matiz A, Valencia GR, Rosenthal M, Persky VW, Uyeda K, Williams R, Banda E, Ramirez-Diaz E, Reyes BM, Montoya J, West C.

Health Promot Pract. 2011 Nov;12(6 Suppl 1):34S-51S. doi: 10.1177/1524839911415665.

PMID:
22068359
24.

Cross-site evaluation of a comprehensive pediatric asthma project: the Merck Childhood Asthma Network, Inc. (MCAN).

Viswanathan M, Mansfield C, Smith LR, Woodell C, Darcy N, Ohadike YU, Lesch JK, Malveaux FJ.

Health Promot Pract. 2011 Nov;12(6 Suppl 1):20S-33S. doi: 10.1177/1524839911412595.

PMID:
22068358
25.

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.

Ramirez-Carrozzi V, Sambandam A, Luis E, Lin Z, Jeet S, Lesch J, Hackney J, Kim J, Zhou M, Lai J, Modrusan Z, Sai T, Lee W, Xu M, Caplazi P, Diehl L, de Voss J, Balazs M, Gonzalez L Jr, Singh H, Ouyang W, Pappu R.

Nat Immunol. 2011 Oct 12;12(12):1159-66. doi: 10.1038/ni.2156.

PMID:
21993848
26.

Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth.

Yakes FM, Chen J, Tan J, Yamaguchi K, Shi Y, Yu P, Qian F, Chu F, Bentzien F, Cancilla B, Orf J, You A, Laird AD, Engst S, Lee L, Lesch J, Chou YC, Joly AH.

Mol Cancer Ther. 2011 Dec;10(12):2298-308. doi: 10.1158/1535-7163.MCT-11-0264. Epub 2011 Sep 16.

27.

2008 Kremers Award Lecture. Dreams of reason: Historical perspective on rational drug design.

Lesch JE.

Pharm Hist. 2008;50(4):131-9. No abstract available.

PMID:
19831019
28.

Robotics and tele-manipulation: update and perspectives in urology.

Frede T, Jaspers J, Hammady A, Lesch J, Teber D, Rassweiler J.

Minerva Urol Nefrol. 2007 Jun;59(2):179-89. Review.

PMID:
17571054
29.

The discovery of M & B 693 (sulfapyridine)

Lesch JE.

Publ Am Inst Hist Pharm. 1997;16:101-19. No abstract available.

PMID:
11619887
30.

Reformers in physiology.

Lesch JE.

Science. 1982 Nov 26;218(4575):879. No abstract available.

PMID:
17807138
31.

Two-chain subunit structure of HLA-D antigens.

Billing R, Safani M, Lesch J.

Tissue Antigens. 1977 Oct;10(4):267-72.

PMID:
144335
32.

[Construction, function, technic and use of crown-pin-systems in the partial denture].

Lesch J.

Zahntechnik (Berl). 1970 Sep;11(9):383-9. German. No abstract available.

PMID:
5278076

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