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Items: 1 to 50 of 328

1.

Non-Alcoholic Fatty Liver Disease, and the Underlying Altered Fatty Acid Metabolism, Reveals Brain Hypoperfusion and Contributes to the Cognitive Decline in APP/PS1 Mice.

Pinçon A, De Montgolfier O, Akkoyunlu N, Daneault C, Pouliot P, Villeneuve L, Lesage F, Levy BI, Thorin-Trescases N, Thorin É, Ruiz M.

Metabolites. 2019 May 25;9(5). pii: E104. doi: 10.3390/metabo9050104.

2.

Incidence and Clinical Impact of Anti-TNFα Treatment of Severe Immune Checkpoint Inhibitor-induced Colitis in Advanced Melanoma: The Mecolit Survey.

Lesage C, Longvert C, Prey S, Maanaoui S, Dréno B, Machet L, Zehou O, Kramkimel N, Jeudy G, Skowron F, Aubin F, Visseaux L, Mansard S, Dereure O, Lesage FX, Guillot B; French Group of Onco-Dermatology.

J Immunother. 2019 May 15. doi: 10.1097/CJI.0000000000000268. [Epub ahead of print]

PMID:
31107372
3.

Systolic hypertension-induced neurovascular unit disruption magnifies vascular cognitive impairment in middle-age atherosclerotic LDLr-/-:hApoB+/+ mice.

de Montgolfier O, Pouliot P, Gillis MA, Ferland G, Lesage F, Thorin-Trescases N, Thorin É.

Geroscience. 2019 May 15. doi: 10.1007/s11357-019-00070-6. [Epub ahead of print]

PMID:
31093829
4.

Incidence and Clinical Impact of Anti-TNFα Treatment of Severe Immune Checkpoint Inhibitor-induced Colitis in Advanced Melanoma: The Mecolit Survey.

Lesage C, Longvert C, Prey S, Maanaoui S, Dréno B, Machet L, Zehou O, Kramkimel N, Jeudy G, Skowron F, Aubin F, Visseaux L, Mansard S, Dereure O, Lesage FX, Guillot B; French Group of Onco-Dermatology.

J Immunother. 2019 Jun;42(5):175-179. doi: 10.1097/CJI.0000000000000268.

PMID:
31090656
5.

Multifaceted Program to Reduce Job Strain in ICU Nurses.

Lesage FX, Choron G, Dutheil F.

JAMA. 2019 Apr 9;321(14):1410-1411. doi: 10.1001/jama.2019.0570. No abstract available.

PMID:
30964523
6.

MK5 haplodeficiency decreases collagen deposition and scar size during post-myocardial infarction wound repair.

Nawaito SA, Sahadevan P, Clavet-Lanthier MÉ, Pouliot P, Sahmi F, Shi Y, Gillis MA, Lesage F, Gaestel M, Sirois MG, Calderone A, Tardif JC, Allen BG.

Am J Physiol Heart Circ Physiol. 2019 Jun 1;316(6):H1281-H1296. doi: 10.1152/ajpheart.00532.2017. Epub 2019 Mar 22.

PMID:
30901279
7.

In Vivo Near-Infrared Fluorescence Imaging of Atherosclerosis Using Local Delivery of Novel Targeted Molecular Probes.

Bertrand MJ, Abran M, Maafi F, Busseuil D, Merlet N, Mihalache-Avram T, Geoffroy P, Tardif PL, Abulrob A, Arbabi-Ghahroudi M, Ni F, Sirois M, L'Allier PL, Rhéaume É, Lesage F, Tardif JC.

Sci Rep. 2019 Feb 25;9(1):2670. doi: 10.1038/s41598-019-38970-4.

8.

Mutation of a single residue promotes gating of vertebrate and invertebrate two-pore domain potassium channels.

Ben Soussia I, El Mouridi S, Kang D, Leclercq-Blondel A, Khoubza L, Tardy P, Zariohi N, Gendrel M, Lesage F, Kim EJ, Bichet D, Andrini O, Boulin T.

Nat Commun. 2019 Feb 15;10(1):787. doi: 10.1038/s41467-019-08710-3.

9.

Integration of a Raman spectroscopy system to a robotic-assisted surgical system for real-time tissue characterization during radical prostatectomy procedures.

Pinto M, Zorn KC, Tremblay JP, Desroches J, Dallaire F, Aubertin K, Marple E, Kent C, Leblond F, Trudel D, Lesage F.

J Biomed Opt. 2019 Feb;24(2):1-10. doi: 10.1117/1.JBO.24.2.025001.

PMID:
30767440
10.

Cerebral tissue pO2 response to stimulation is preserved with age in awake mice.

Moeini M, Lu X, Bélanger S, Picard F, Boas D, Kakkar A, Lesage F.

Neurosci Lett. 2019 Apr 23;699:160-166. doi: 10.1016/j.neulet.2019.02.007. Epub 2019 Feb 7.

11.

fNIRS improves seizure detection in multimodal EEG-fNIRS recordings.

Sirpal P, Kassab A, Pouliot P, Nguyen DK, Lesage F.

J Biomed Opt. 2019 Feb;24(5):1-9. doi: 10.1117/1.JBO.24.5.051408.

PMID:
30734544
12.

Fully automated dual-resolution serial optical coherence tomography aimed at diffusion MRI validation in whole mouse brains.

Lefebvre J, Delafontaine-Martel P, Pouliot P, Girouard H, Descoteaux M, Lesage F.

Neurophotonics. 2018 Oct;5(4):045004. doi: 10.1117/1.NPh.5.4.045004. Epub 2018 Nov 3.

PMID:
30681668
13.

Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK.

Royal P, Andres-Bilbe A, Ávalos Prado P, Verkest C, Wdziekonski B, Schaub S, Baron A, Lesage F, Gasull X, Levitz J, Sandoz G.

Neuron. 2019 Jan 16;101(2):232-245.e6. doi: 10.1016/j.neuron.2018.11.039. Epub 2018 Dec 17.

PMID:
30573346
14.

High Systolic Blood Pressure Induces Cerebral Microvascular Endothelial Dysfunction, Neurovascular Unit Damage, and Cognitive Decline in Mice.

de Montgolfier O, Pinçon A, Pouliot P, Gillis MA, Bishop J, Sled JG, Villeneuve L, Ferland G, Lévy BI, Lesage F, Thorin-Trescases N, Thorin É.

Hypertension. 2019 Jan;73(1):217-228. doi: 10.1161/HYPERTENSIONAHA.118.12048.

PMID:
30571552
15.

Automatic Graph-based Modeling of Brain Microvessels Captured with Two-Photon Microscopy.

Damseh R, Pouliot P, Gagnon L, Sakadzic S, Boas D, Cheriet F, Lesage F.

IEEE J Biomed Health Inform. 2018 Dec 3. doi: 10.1109/JBHI.2018.2884678. [Epub ahead of print]

PMID:
30507542
16.

Psychosocial risks and work suffering

Lesage FX.

Rev Prat. 2017 Dec;67(10):1071-1074. French.

PMID:
30512602
17.

Fully Convolutional DenseNets for Segmentation of Microvessels in Two-photon Microscopy.

Damseh R, Cheriet F, Lesage F.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:661-665. doi: 10.1109/EMBC.2018.8512285.

PMID:
30440483
18.

Synthetic Methodologies to Gold Nanoshells: An Overview.

Wang YC, Rhéaume É, Lesage F, Kakkar A.

Molecules. 2018 Nov 2;23(11). pii: E2851. doi: 10.3390/molecules23112851. Review.

19.

Nanotherapies for micropreemies: Stem cells and the secretome in bronchopulmonary dysplasia.

Lesage F, Thébaud B.

Semin Perinatol. 2018 Nov;42(7):453-458. doi: 10.1053/j.semperi.2018.09.007. Epub 2018 Oct 6. Review.

PMID:
30376986
20.

Antagonistic Effect of a Cytoplasmic Domain on the Basal Activity of Polymodal Potassium Channels.

Soussia IB, Choveau FS, Blin S, Kim EJ, Feliciangeli S, Chatelain FC, Kang D, Bichet D, Lesage F.

Front Mol Neurosci. 2018 Sep 4;11:301. doi: 10.3389/fnmol.2018.00301. eCollection 2018.

21.

Lack of p11 expression facilitates acidity-sensing function of TASK1 channels in mouse adrenal medullary cells.

Inoue M, Matsuoka H, Lesage F, Harada K.

FASEB J. 2019 Jan;33(1):455-468. doi: 10.1096/fj.201800407RR. Epub 2018 Jul 12.

PMID:
30001168
22.

Whole brain vascular imaging in a mouse model of Alzheimer's disease with two-photon microscopy.

Delafontaine-Martel P, Lefebvre J, Tardif PL, Lévy BI, Pouliot P, Lesage F.

J Biomed Opt. 2018 Jul;23(7):1-10. doi: 10.1117/1.JBO.23.7.076501.

PMID:
29998647
23.

Incidence of ill-health related job loss and related social and occupational factors. The "unfit for the job" study: a one-year follow-up study of 51,132 workers.

Lesage FX, Dutheil F, Godderis L, Divies A, Choron G.

PeerJ. 2018 Jun 19;6:e5073. doi: 10.7717/peerj.5073. eCollection 2018.

24.

Occupational exposure factors for mental and behavioral disorders at work: The FOREC thesaurus.

Chamoux A, Lambert C, Vilmant A, Lanhers C, Agius R, Boutaleb M, Bonneterre V, Naughton G, Pereira B, Djeriri K, Ben-Brik E, Breton C, De Clavière C, Letheux C, Paolillo AG, Valenty M, Vandenberghe O, Aeschlimann MP, Lasfargues G; Members of the RNV3P, Lesage FX, Dutheil F.

PLoS One. 2018 Jun 21;13(6):e0198719. doi: 10.1371/journal.pone.0198719. eCollection 2018.

25.

Piperacillin Population Pharmacokinetics and Dosing Regimen Optimization in Critically Ill Children with Normal and Augmented Renal Clearance.

Béranger A, Benaboud S, Urien S, Moulin F, Bille E, Lesage F, Zheng Y, Genuini M, Gana I, Renolleau S, Hirt D, Tréluyer JM, Oualha M.

Clin Pharmacokinet. 2019 Feb;58(2):223-233. doi: 10.1007/s40262-018-0682-1.

PMID:
29862466
26.

Compromised microvascular oxygen delivery increases brain tissue vulnerability with age.

Moeini M, Lu X, Avti PK, Damseh R, Bélanger S, Picard F, Boas D, Kakkar A, Lesage F.

Sci Rep. 2018 May 29;8(1):8219. doi: 10.1038/s41598-018-26543-w.

27.

Population pharmacokinetics of enoxaparin in early stage of paediatric liver transplantation.

Oualha M, Chardot C, Debray D, Lesage F, Harroche A, Renolleau S, Treluyer JM, Urien S.

Br J Clin Pharmacol. 2018 Jun;84(6):1206-1214. doi: 10.1111/bcp.13543. Epub 2018 Mar 23.

28.

Postdiarrheal hemolytic and uremic syndrome with severe multiorgan involvement and associated early risk factors.

Oualha M, Pierrepont S, Krug P, Gitiaux C, Hubert P, Lesage F, Salomon R.

Arch Pediatr. 2018 Feb;25(2):118-125. doi: 10.1016/j.arcped.2017.12.005. Epub 2018 Feb 1.

PMID:
29395881
29.

Achievement of Therapeutic Vancomycin Exposure With Continuous Infusion in Critically Ill Children.

Genuini M, Oualha M, Bouazza N, Moulin F, Treluyer JM, Lesage F, Renolleau S, Benaboud S.

Pediatr Crit Care Med. 2018 Jun;19(6):e263-e269. doi: 10.1097/PCC.0000000000001474.

PMID:
29394210
30.

Upregulation of Vascular Endothelial Growth Factor in Amniotic Fluid Stem Cells Enhances Their Potential to Attenuate Lung Injury in a Preterm Rabbit Model of Bronchopulmonary Dysplasia.

Jiménez J, Lesage F, Richter J, Nagatomo T, Salaets T, Zia S, Mori Da Cunha MG, Vanoirbeek J, Deprest JA, Toelen J.

Neonatology. 2018;113(3):275-285. doi: 10.1159/000481794. Epub 2018 Feb 1.

PMID:
29393249
31.

Design and construction of an optimized transmit/receive hybrid birdcage resonator to improve full body images of medium-sized animals in 7T scanner.

Lopez Rios N, Pouliot P, Papoutsis K, Foias A, Stikov N, Lesage F, Dehaes M, Cohen-Adad J.

PLoS One. 2018 Feb 1;13(2):e0192035. doi: 10.1371/journal.pone.0192035. eCollection 2018.

32.

Early Noninvasive Ventilation and Nonroutine Transfusion for Acute Chest Syndrome in Sickle Cell Disease in Children: A Descriptive Study.

Heilbronner C, Merckx A, Brousse V, Allali S, Hubert P, de Montalembert M, Lesage F.

Pediatr Crit Care Med. 2018 May;19(5):e235-e241. doi: 10.1097/PCC.0000000000001468.

PMID:
29356722
33.

Comparing three-dimensional serial optical coherence tomography histology to MRI imaging in the entire mouse brain.

Castonguay A, Lefebvre J, Lesage F, Pouliot P.

J Biomed Opt. 2018 Jan;23(1):1-9. doi: 10.1117/1.JBO.23.1.016008.

PMID:
29313322
34.

siRNA Delivery with Chitosan: Influence of Chitosan Molecular Weight, Degree of Deacetylation, and Amine to Phosphate Ratio on in Vitro Silencing Efficiency, Hemocompatibility, Biodistribution, and in Vivo Efficacy.

Alameh M, Lavertu M, Tran-Khanh N, Chang CY, Lesage F, Bail M, Darras V, Chevrier A, Buschmann MD.

Biomacromolecules. 2018 Jan 8;19(1):112-131. doi: 10.1021/acs.biomac.7b01297. Epub 2017 Dec 28.

PMID:
29211954
35.

Serial optical coherence scanning reveals an association between cardiac function and the heart architecture in the aging rodent heart.

Castonguay A, Lefebvre J, Pouliot P, Avti P, Moeini M, Lesage F.

Biomed Opt Express. 2017 Oct 16;8(11):5027-5038. doi: 10.1364/BOE.8.005027. eCollection 2017 Nov 1.

36.

Decreased prevalence of cancer in patients with multiple sclerosis: A case-control study.

Moisset X, Perié M, Pereira B, Dumont E, Lebrun-Frenay C, Lesage FX, Dutheil F, Taithe F, Clavelou P.

PLoS One. 2017 Nov 27;12(11):e0188120. doi: 10.1371/journal.pone.0188120. eCollection 2017.

37.

[Acute hemorrhagic edema of infancy associated with Coxsackie virus infection].

Debray A, Ollier V, Coutard A, Arditty F, Bekkar S, Bodemer C, Leruez-Ville M, Mirand A, Lesage F, Foucaud P.

Arch Pediatr. 2017 Dec;24(12):1262-1266. doi: 10.1016/j.arcped.2017.09.013. Epub 2017 Nov 22. French.

PMID:
29174007
38.

Multichannel wearable fNIRS-EEG system for long-term clinical monitoring.

Kassab A, Le Lan J, Tremblay J, Vannasing P, Dehbozorgi M, Pouliot P, Gallagher A, Lesage F, Sawan M, Nguyen DK.

Hum Brain Mapp. 2018 Jan;39(1):7-23. doi: 10.1002/hbm.23849. Epub 2017 Oct 23.

PMID:
29058341
39.

Prenatal factors associated with neonatal survival of infants with congenital chylothorax.

Dorsi M, Giuseppi A, Lesage F, Stirnemann J, De Saint Blanquat L, Nicloux M, Assaf Z, Khen Dunlop N, Kermorvant-Duchemin E, Magny JF, Ville Y, Lapillonne A.

J Perinatol. 2018 Jan;38(1):31-34. doi: 10.1038/jp.2017.150. Epub 2017 Oct 19.

PMID:
29048403
40.

Long-term metabolic follow-up and clinical outcome of 35 patients with maple syrup urine disease.

Abi-Wardé MT, Roda C, Arnoux JB, Servais A, Habarou F, Brassier A, Pontoizeau C, Barbier V, Bayart M, Leboeuf V, Chadefaux-Vekemans B, Dubois S, Assoun M, Belloche C, Alili JM, Husson MC, Lesage F, Dupic L, Theuil B, Ottolenghi C, de Lonlay P.

J Inherit Metab Dis. 2017 Nov;40(6):783-792. doi: 10.1007/s10545-017-0083-x. Epub 2017 Sep 13.

PMID:
28905140
41.

The amniotic fluid as a source of mesenchymal stem cells with lung-specific characteristics.

Lesage F, Zia S, Jiménez J, Deprest J, Toelen J.

Prenat Diagn. 2017 Nov;37(11):1093-1099. doi: 10.1002/pd.5147. Epub 2017 Oct 15.

PMID:
28842991
42.

Hyperoxia treatment of TREK-1/TREK-2/TRAAK-deficient mice is associated with a reduction in surfactant proteins.

Schwingshackl A, Lopez B, Teng B, Luellen C, Lesage F, Belperio J, Olcese R, Waters CM.

Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1030-L1046. doi: 10.1152/ajplung.00121.2017. Epub 2017 Aug 24.

43.

Astrocytic endfoot Ca2+ correlates with parenchymal vessel responses during 4-AP induced epilepsy: An in vivo two-photon lifetime microscopy study.

Zhang C, Tabatabaei M, Bélanger S, Girouard H, Moeini M, Lu X, Lesage F.

J Cereb Blood Flow Metab. 2019 Feb;39(2):260-271. doi: 10.1177/0271678X17725417. Epub 2017 Aug 9.

PMID:
28792278
44.

Minimal modulation of the host immune response to SIS matrix implants by mesenchymal stem cells from the amniotic fluid.

Lesage F, Pranpanus S, Bosisio FM, Jacobs M, Ospitalieri S, Toelen J, Deprest J.

Hernia. 2017 Dec;21(6):973-982. doi: 10.1007/s10029-017-1635-6. Epub 2017 Jul 27.

PMID:
28752425
45.

Altered Functional Connectivity Following an Inflammatory White Matter Injury in the Newborn Rat: A High Spatial and Temporal Resolution Intrinsic Optical Imaging Study.

Guevara E, Pierre WC, Tessier C, Akakpo L, Londono I, Lesage F, Lodygensky GA.

Front Neurosci. 2017 Jul 4;11:358. doi: 10.3389/fnins.2017.00358. eCollection 2017.

46.

Whole mouse brain imaging using optical coherence tomography: reconstruction, normalization, segmentation, and comparison with diffusion MRI.

Lefebvre J, Castonguay A, Pouliot P, Descoteaux M, Lesage F.

Neurophotonics. 2017 Oct;4(4):041501. doi: 10.1117/1.NPh.4.4.041501. Epub 2017 Jul 11.

47.

Cellular origin of intrinsic optical signals in the rabbit retina.

Naderian A, Bussières L, Thomas S, Lesage F, Casanova C.

Vision Res. 2017 Aug;137:40-49. doi: 10.1016/j.visres.2017.04.015. Epub 2017 Jul 14.

48.

Abnormal respiration under hyperoxia in TASK-1/3 potassium channel double knockout mice.

Buehler PK, Bleiler D, Tegtmeier I, Heitzmann D, Both C, Georgieff M, Lesage F, Warth R, Thomas J.

Respir Physiol Neurobiol. 2017 Oct;244:17-25. doi: 10.1016/j.resp.2017.06.009. Epub 2017 Jul 1.

PMID:
28673876
49.

At-risk and intervention thresholds of occupational stress using a visual analogue scale.

Dutheil F, Pereira B, Moustafa F, Naughton G, Lesage FX, Lambert C.

PLoS One. 2017 Jun 6;12(6):e0178948. doi: 10.1371/journal.pone.0178948. eCollection 2017.

50.

Modulation of the Early Host Response to Electrospun Polylactic Acid Matrices by Mesenchymal Stem Cells from the Amniotic Fluid.

Lesage F, Roman S, Pranpanus S, Ospitalieri S, Zia S, Jimenez J, MacNeil S, Toelen J, Deprest J.

Eur J Pediatr Surg. 2018 Jun;28(3):285-292. doi: 10.1055/s-0037-1603522. Epub 2017 May 31.

PMID:
28564708

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