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Items: 1 to 50 of 104

1.

Inborn errors of metabolism in the light of metabolic control analysis.

Mazat JP, Letellier T, Malgat M, Rossignol R, Korzeniewski B, Demaugre F, Leroux JP.

Biochem Soc Trans. 1998 May;26(2):141-5. Review. No abstract available.

PMID:
9649736
2.

The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA.

Helm M, Brulé H, Degoul F, Cepanec C, Leroux JP, Giegé R, Florentz C.

Nucleic Acids Res. 1998 Apr 1;26(7):1636-43.

3.

Molecular analysis of carnitine palmitoyltransferase II deficiency with hepatocardiomuscular expression.

Bonnefont JP, Taroni F, Cavadini P, Cepanec C, Brivet M, Saudubray JM, Leroux JP, Demaugre F.

Am J Hum Genet. 1996 May;58(5):971-8.

4.

Impairment of the mitochondrial respiratory chain activity in diethylnitrosamine-induced rat hepatomas: possible involvement of oxygen free radicals.

Boitier E, Merad-Boudia M, Guguen-Guillouzo C, Defer N, Ceballos-Picot I, Leroux JP, Marsac C.

Cancer Res. 1995 Jul 15;55(14):3028-35.

5.

Presence of proteins recognized by mammalian cytochrome P-450 antibodies in Euglena gracilis.

Briand J, Julistiono H, Beaune P, Flinois JP, de Waziers I, Leroux JP.

Biochim Biophys Acta. 1993 Dec 8;1203(2):199-204.

PMID:
8268200
6.

Defect in the lipoyl-bearing protein X subunit of the pyruvate dehydrogenase complex in two patients with encephalomyelopathy.

Marsac C, Stansbie D, Bonne G, Cousin J, Jehenson P, Benelli C, Leroux JP, Lindsay G.

J Pediatr. 1993 Dec;123(6):915-20.

PMID:
8229524
7.

Major pathway of imipramine metabolism is catalyzed by cytochromes P-450 1A2 and P-450 3A4 in human liver.

Lemoine A, Gautier JC, Azoulay D, Kiffel L, Belloc C, Guengerich FP, Maurel P, Beaune P, Leroux JP.

Mol Pharmacol. 1993 May;43(5):827-32.

PMID:
8502233
8.

E1 pyruvate dehydrogenase deficiency in a child with motor neuropathy.

Bonne G, Benelli C, De Meirleir L, Lissens W, Chaussain M, Diry M, Clot JP, Ponsot G, Geoffroy V, Leroux JP, et al.

Pediatr Res. 1993 Mar;33(3):284-8.

PMID:
8460066
9.

Cytochrome P450 induction and mutagenicity of 2-aminoanthracene (2AA) in rat liver and gut.

Carrière V, de Waziers I, Courtois YA, Leroux JP, Beaune PH.

Mutat Res. 1992 Jul;268(1):11-20.

PMID:
1378177
10.

Pathophysiological approach to carnitine palmitoyltransferase II deficiencies.

Demaugre F, Bonnefont JP, Brivet M, Cepanec C, Pollitt RJ, Priestley BL, Saudubray JM, Leroux JP.

Prog Clin Biol Res. 1992;375:301-8. No abstract available.

PMID:
1438375
11.

Hormonal regulation of microsomal flavin-containing monooxygenase: tissue-dependent expression and substrate specificity.

Lemoine A, Williams DE, Cresteil T, Leroux JP.

Mol Pharmacol. 1991 Aug;40(2):211-7.

PMID:
1875908
12.

Drug-metabolizing enzyme expression in human normal, peritumoral and tumoral colorectal tissue samples.

de Waziers I, Cugnenc PH, Berger A, Leroux JP, Beaune PH.

Carcinogenesis. 1991 May;12(5):905-9.

PMID:
2029756
14.

Immunoquantitative analysis of human carnitine palmitoyltransferase I and II defects.

Demaugre F, Bonnefont JP, Cepanec C, Scholte J, Saudubray JM, Leroux JP.

Pediatr Res. 1990 May;27(5):497-500.

PMID:
2345677
15.

Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues.

de Waziers I, Cugnenc PH, Yang CS, Leroux JP, Beaune PH.

J Pharmacol Exp Ther. 1990 Apr;253(1):387-94.

PMID:
2329521
16.

A human cytochrome P-450 is recognized by anti-liver/kidney microsome antibodies in autoimmune chronic hepatitis.

Kiffel L, Loeper J, Homberg JC, Leroux JP.

Biochem Biophys Res Commun. 1989 Feb 28;159(1):283-9.

PMID:
2466461
17.

Ontogeny and regulation of drug metabolism in humans. Phase I: Monooxygenases.

Leroux JP, Cresteil T, Marie S.

Dev Pharmacol Ther. 1989;13(2-4):63-9. Review.

PMID:
2693005
18.

Purification and characterization of a cytochrome P-450 isozyme isolated from the liver of rats pretreated with clofibrate.

Kiffel L, Célier C, Leroux JP.

Biochem Biophys Res Commun. 1988 Oct 14;156(1):282-9.

PMID:
3140811
19.

Purification and comparison of liver microsomal flavin-containing monooxygenase from normal and streptozotocin-diabetic rats.

Rouer E, Rouet P, Delpech M, Leroux JP.

Biochem Pharmacol. 1988 Sep 15;37(18):3455-9.

PMID:
3421995
20.

Hydrophobic chromatography: a one-step method for the purification of human liver microsomal epoxide hydrolase.

Beaune PH, Cresteil T, Flinois JP, Leroux JP.

J Chromatogr. 1988 Apr 8;426(1):169-76. No abstract available.

PMID:
3384870
21.
23.

Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug.

Beaune P, Dansette PM, Mansuy D, Kiffel L, Finck M, Amar C, Leroux JP, Homberg JC.

Proc Natl Acad Sci U S A. 1987 Jan;84(2):551-5.

24.

Immunoquantitation of some cytochrome P-450 isozymes in liver microsomes from streptozotocin-diabetic rats.

Rouer E, Beaune P, Leroux JP.

Experientia. 1986 Oct 15;42(10):1162-3.

PMID:
3770136
25.

The effect of adenosine and chloroadenosine on sex differences in the energy metabolism of rat hepatocytes.

Buc HA, Demaugre F, Cépanec C, Moncion A, Leroux JP.

Biochim Biophys Acta. 1986 Jul 11;887(2):222-8.

PMID:
3719010
26.

Cytochrome P-450 isoenzyme content and monooxygenase activities in rat liver: effect of ontogenesis and pretreatment by phenobarbital and 3-methylcholanthrene.

Cresteil T, Beaune P, Celier C, Leroux JP, Guengerich FP.

J Pharmacol Exp Ther. 1986 Jan;236(1):269-76.

PMID:
3941398
27.

Immunoquantification of epoxide hydrolase and cytochrome P-450 isozymes in fetal and adult human liver microsomes.

Cresteil T, Beaune P, Kremers P, Celier C, Guengerich FP, Leroux JP.

Eur J Biochem. 1985 Sep 2;151(2):345-50.

28.

Purification of a new cytochrome P-450 from human liver microsomes.

Beaune P, Flinois JP, Kiffel L, Kremers P, Leroux JP.

Biochim Biophys Acta. 1985 Jul 5;840(3):364-70.

PMID:
4005291
29.

[The compromise of relinquishment].

Leroux JP.

Infirm Fr. 1985 May;(265):7-8. French. No abstract available.

PMID:
3849494
30.
31.

Spin state studies on cytochrome P-450 in liver microsomes from obese and diabetic animals.

Rouer E, Delaforge M, Rocchiccioli F, Gibson GG, Leroux JP.

Biochem Biophys Res Commun. 1985 Jan 16;126(1):615-21.

PMID:
2982381
32.

[Developmental bilharziasis caused by Schistosoma mansoni discovered 37 years after infestation].

Chabasse D, Bertrand G, Leroux JP, Gauthey N, Hocquet P.

Bull Soc Pathol Exot Filiales. 1985;78(5):643-7. French.

PMID:
3936631
34.
35.

Induction of drug-metabolizing enzymes by tricyclic antidepressants in human liver: characterization and partial resolution of cytochromes P-450.

Cresteil T, Célier C, Kremers P, Flinois JP, Beaune P, Leroux JP.

Br J Clin Pharmacol. 1983 Dec;16(6):651-7.

37.

Influence of oxalate on the rate of the tricarboxylic acid cycle in rat hepatocytes.

Buc HA, Augereau C, Demaugre F, Moncion A, Leroux JP.

Biochim Biophys Acta. 1983 Sep 22;763(2):220-3.

PMID:
6615892
38.

Influence of ethanol and benzene on cytochrome P-450 fractions in rat liver microsomes.

Beaune P, Flinois JP, Le Provost E, Leroux JP.

Drug Metab Dispos. 1983 Sep-Oct;11(5):499-506.

PMID:
6138238
39.

Comparison of the effects of 2-chloropropionate and dichloroacetate on ketogenesis and lipogenesis in isolated rat hepatocytes.

Demaugre F, Buc HA, Cepanec C, Moncion A, Leroux JP.

Biochem Pharmacol. 1983 Jun 15;32(12):1881-5.

PMID:
6882465
41.

Role of the mitochondrial metabolism of pyruvate on the regulation of ketogenesis in rat hepatocytes.

Demaugre F, Buc H, Girard J, Leroux JP.

Metabolism. 1983 Jan;32(1):40-8.

PMID:
6848896
42.

Induction of drug metabolizing enzymes in the liver of diabetic mice.

Rouer E, Mahu JL, Columelli S, Dansette P, Leroux JP.

Biochimie. 1982 Oct;64(10):961-7.

PMID:
6295511
43.

[Role of monoxygenases in the metabolism of drugs in the human fetus and newborn infant].

Cresteil T, Leroux JP.

Arch Fr Pediatr. 1982 Aug-Sep;39(7):463-70. Review. French.

PMID:
6816186
44.

Enzymatic and immunological characterization of cytochromes P 450 from ellipticine-treated rat liver.

Cresteil T, Le Provost E, Leroux JP, Lesca P.

Biochem Biophys Res Commun. 1982 Aug;107(3):1037-45. No abstract available.

PMID:
6814430
45.

Enzymatic and immunological evidences that phenobarbital induces cytochrome P 450 in fetal and neonatal rat liver.

Cresteil T, Le Provost E, Flinois JP, Leroux JP.

Biochem Biophys Res Commun. 1982 Jun 15;106(3):823-30. No abstract available.

PMID:
7115377
46.

Effects of oxalate and dichloroacetate on lipogenesis and ketogenesis in rat hepatocytes.

Buc HA, Demaugre F, Moncion A, Leroux JP.

Biochem Biophys Res Commun. 1982 Feb 11;104(3):1107-13. No abstract available.

PMID:
7073727
47.

Drug-metabolizing enzymes in human foetal liver: partial resolution of multiple cytochromes P 450.

Cresteil T, Beaune P, Kremers P, Flinois JP, Leroux JP.

Pediatr Pharmacol (New York). 1982;2(3):199-207.

PMID:
7162874
48.
49.

Quantitative gas chromatography--chemical ionization mass spectrometry of 2-ketoglutarate from urine as its O-trimethylsilyl-quinoxalinol derivative.

Rocchiccioli F, Leroux JP, Cartier P.

J Chromatogr. 1981 Dec 11;226(2):325-32. No abstract available.

PMID:
7320163
50.

Cytochrome P-450 monooxygenase activities in human and rat liver microsomes.

Kremers P, Beaune P, Cresteil T, de Graeve J, Columelli S, Leroux JP, Gielen JE.

Eur J Biochem. 1981 Sep 1;118(3):599-606.

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