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Items: 1 to 50 of 536

1.

An Investigation of PS-b-PEO Polymersomes for the Oral Treatment and Diagnosis of Hyperammonemia.

Matoori S, Bao Y, Schmidt A, Fischer EJ, Ochoa-Sanchez R, Tremblay M, Oliveira MM, Rose CF, Leroux JC.

Small. 2019 Dec;15(50):e1902347. doi: 10.1002/smll.201902347. Epub 2019 Nov 13.

PMID:
31721441
2.

The Illusion and Disillusion of Peer Review.

Leroux JC.

ACS Nano. 2019 Sep 24;13(9):9696-9697. doi: 10.1021/acsnano.9b07238. No abstract available.

PMID:
31614411
3.

Opposing roles of endothelial and leukocyte-expressed IL-7Rα in the regulation of psoriasis-like skin inflammation.

Vranova M, Friess MC, Haghayegh Jahromi N, Collado-Diaz V, Vallone A, Hagedorn O, Jadhav M, Willrodt AH, Polomska A, Leroux JC, Proulx ST, Halin C.

Sci Rep. 2019 Aug 12;9(1):11714. doi: 10.1038/s41598-019-48046-y.

4.

Ultra-sub-stoichiometric "Dynamic" Bioconjugation Reduces Viscosity by Disrupting Immunoglobulin Oligomerization.

Gong Y, Soleymani Abyaneh H, Drossis N, Niederquell A, Kuentz M, Leroux JC, de Haan HW, Gauthier MA.

Biomacromolecules. 2019 Sep 9;20(9):3557-3565. doi: 10.1021/acs.biomac.9b00867. Epub 2019 Aug 23.

PMID:
31398010
5.

Understanding the preferences of water users in a context of cyanobacterial blooms in Quebec.

L'Ecuyer-Sauvageau C, Kermagoret C, Dupras J, He J, Leroux J, Schinck MP, Poder TG.

J Environ Manage. 2019 Oct 15;248:109271. doi: 10.1016/j.jenvman.2019.109271. Epub 2019 Aug 1.

PMID:
31377540
6.

Delivery of Rapamycin Using In Situ Forming Implants Promotes Immunoregulation and Vascularized Composite Allograft Survival.

Sutter D, Dzhonova DV, Prost JC, Bovet C, Banz Y, Rahnfeld L, Leroux JC, Rieben R, Vögelin E, Plock JA, Luciani P, Taddeo A, Schnider JT.

Sci Rep. 2019 Jun 25;9(1):9269. doi: 10.1038/s41598-019-45759-y.

7.

Dual delivery of nucleic acids and PEGylated-bisphosphonates via calcium phosphate nanoparticles.

Bisso S, Mura S, Castagner B, Couvreur P, Leroux JC.

Eur J Pharm Biopharm. 2019 Sep;142:142-152. doi: 10.1016/j.ejpb.2019.06.013. Epub 2019 Jun 17.

PMID:
31220571
8.

Benefit-Cost Analysis of an Innovative Program for Self-Sufficiency and Homeownership.

Galster GC, Santiago AM, Smith RJ, Leroux J.

Eval Rev. 2019 Feb-Apr;43(1-2):3-40. doi: 10.1177/0193841X19846697. Epub 2019 May 23.

PMID:
31122070
9.

The macrocyclizing protease butelase 1 remains autocatalytic and reveals the structural basis for ligase activity.

James AM, Haywood J, Leroux J, Ignasiak K, Elliott AG, Schmidberger JW, Fisher MF, Nonis SG, Fenske R, Bond CS, Mylne JS.

Plant J. 2019 Jun;98(6):988-999. doi: 10.1111/tpj.14293. Epub 2019 Mar 28.

PMID:
30790358
10.

Minimally invasive method for the point-of-care quantification of lymphatic vessel function.

Polomska AK, Proulx ST, Brambilla D, Fehr D, Bonmarin M, Brändli S, Meboldt M, Steuer C, Vasileva T, Reinke N, Leroux JC, Detmar M.

JCI Insight. 2019 Feb 21;4(4). pii: 126515. doi: 10.1172/jci.insight.126515. eCollection 2019 Feb 21.

11.

Lipids and polymers in pharmaceutical technology: Lifelong companions.

Siepmann J, Faham A, Clas SD, Boyd BJ, Jannin V, Bernkop-Schnürch A, Zhao H, Lecommandoux S, Evans JC, Allen C, Merkel OM, Costabile G, Alexander MR, Wildman RD, Roberts CJ, Leroux JC.

Int J Pharm. 2019 Mar 10;558:128-142. doi: 10.1016/j.ijpharm.2018.12.080. Epub 2019 Jan 9. Review.

12.

Closed-loop cavitation control for focused ultrasound-mediated blood-brain barrier opening by long-circulating microbubbles.

Çavuşoğlu M, Zhang J, Ielacqua GD, Pellegrini G, Signorell RD, Papachristodoulou A, Brambilla D, Roth P, Weller M, Rudin M, Martin E, Leroux JC, Werner B.

Phys Med Biol. 2019 Feb 11;64(4):045012. doi: 10.1088/1361-6560/aafaa5.

PMID:
30577029
13.

Chemotherapy sensitization of glioblastoma by focused ultrasound-mediated delivery of therapeutic liposomes.

Papachristodoulou A, Signorell RD, Werner B, Brambilla D, Luciani P, Cavusoglu M, Grandjean J, Silginer M, Rudin M, Martin E, Weller M, Roth P, Leroux JC.

J Control Release. 2019 Feb 10;295:130-139. doi: 10.1016/j.jconrel.2018.12.009. Epub 2018 Dec 8.

PMID:
30537486
14.

Is 3D Printing of Pharmaceuticals a Disruptor or Enabler?

Liang K, Brambilla D, Leroux JC.

Adv Mater. 2019 Feb;31(5):e1805680. doi: 10.1002/adma.201805680. Epub 2018 Dec 3. Review.

PMID:
30506794
15.

Poly(ethylene glycol)-alendronate coated nanoparticles for magnetic resonance imaging of lymph nodes.

Bisso S, Degrassi A, Brambilla D, Leroux JC.

J Drug Target. 2019 Jun - Jul;27(5-6):659-669. doi: 10.1080/1061186X.2018.1545235. Epub 2018 Dec 4.

PMID:
30513215
16.

Small-Molecule Allosteric Triggers of Clostridium difficile Toxin B Auto-proteolysis as a Therapeutic Strategy.

Ivarsson ME, Durantie E, Huberli C, Huwiler S, Hegde C, Friedman J, Altamura F, Lu J, Verdu EF, Bercik P, Logan SM, Chen W, Leroux JC, Castagner B.

Cell Chem Biol. 2019 Jan 17;26(1):17-26.e13. doi: 10.1016/j.chembiol.2018.10.002. Epub 2018 Oct 25.

17.

Prevalence and Predictors of Food Insecurity among Older People in Canada.

Leroux J, Morrison K, Rosenberg M.

Int J Environ Res Public Health. 2018 Nov 9;15(11). pii: E2511. doi: 10.3390/ijerph15112511.

18.

Intracellular delivery of colloids: Past and future contributions from microinjection.

Tiefenboeck P, Kim JA, Leroux JC.

Adv Drug Deliv Rev. 2018 Jul;132:3-15. doi: 10.1016/j.addr.2018.06.013. Epub 2018 Jun 20. Review.

PMID:
29935217
19.

3D printing of a wearable personalized oral delivery device: A first-in-human study.

Liang K, Carmone S, Brambilla D, Leroux JC.

Sci Adv. 2018 May 9;4(5):eaat2544. doi: 10.1126/sciadv.aat2544. eCollection 2018 May.

20.

Pharmacokinetics of lipid-drug conjugates loaded into liposomes.

Signorell RD, Luciani P, Brambilla D, Leroux JC.

Eur J Pharm Biopharm. 2018 Jul;128:188-199. doi: 10.1016/j.ejpb.2018.04.003. Epub 2018 Apr 18. Review.

PMID:
29678733
21.

The novelty bubble.

Leroux JC.

J Control Release. 2018 May 28;278:140-141. doi: 10.1016/j.jconrel.2018.03.032. Epub 2018 Mar 28. No abstract available.

PMID:
29604310
22.

Liposome-supported peritoneal dialysis in the treatment of severe hyperammonemia: An investigation on potential interactions.

Giacalone G, Matoori S, Agostoni V, Forster V, Kabbaj M, Eggenschwiler S, Lussi M, De Gottardi A, Zamboni N, Leroux JC.

J Control Release. 2018 May 28;278:57-65. doi: 10.1016/j.jconrel.2018.03.030. Epub 2018 Mar 27.

PMID:
29601930
23.

A herbicide structure-activity analysis of the antimalarial lead compound MMV007978 against Arabidopsis thaliana.

Corral MG, Leroux J, Tresch S, Newton T, Stubbs KA, Mylne JS.

Pest Manag Sci. 2018 Jul;74(7):1558-1563. doi: 10.1002/ps.4872. Epub 2018 Mar 5.

PMID:
29377434
24.

Structural properties and gene-silencing activity of chemically modified DNA-RNA hybrids with parallel orientation.

Habibian M, Yahyaee-Anzahaee M, Lucic M, Moroz E, Martín-Pintado N, Di Giovanni LD, Leroux JC, Hall J, González C, Damha MJ.

Nucleic Acids Res. 2018 Feb 28;46(4):1614-1623. doi: 10.1093/nar/gky024.

25.

Peritoneal dialysis beyond kidney failure?

Pratsinis A, Devuyst O, Leroux JC.

J Control Release. 2018 Jul 28;282:3-12. doi: 10.1016/j.jconrel.2018.01.017. Epub 2018 Jan 31. Review.

PMID:
29360477
26.

FAM46A mutations are responsible for autosomal recessive osteogenesis imperfecta.

Doyard M, Bacrot S, Huber C, Di Rocco M, Goldenberg A, Aglan MS, Brunelle P, Temtamy S, Michot C, Otaify GA, Haudry C, Castanet M, Leroux J, Bonnefont JP, Munnich A, Baujat G, Lapunzina P, Monnot S, Ruiz-Perez VL, Cormier-Daire V.

J Med Genet. 2018 Apr;55(4):278-284. doi: 10.1136/jmedgenet-2017-104999. Epub 2018 Jan 22.

PMID:
29358272
27.

Preparation of PEGylated liposomes incorporating lipophilic lomeguatrib derivatives for the sensitization of chemo-resistant gliomas.

Signorell RD, Papachristodoulou A, Xiao J, Arpagaus B, Casalini T, Grandjean J, Thamm J, Steiniger F, Luciani P, Brambilla D, Werner B, Martin E, Weller M, Roth P, Leroux JC.

Int J Pharm. 2018 Jan 30;536(1):388-396. doi: 10.1016/j.ijpharm.2017.11.070. Epub 2017 Dec 2.

PMID:
29198811
28.

Enzyme-Mimetic Antioxidant Luminescent Nanoparticles for Highly Sensitive Hydrogen Peroxide Biosensing.

Pratsinis A, Kelesidis GA, Zuercher S, Krumeich F, Bolisetty S, Mezzenga R, Leroux JC, Sotiriou GA.

ACS Nano. 2017 Dec 26;11(12):12210-12218. doi: 10.1021/acsnano.7b05518. Epub 2017 Dec 4.

PMID:
29182310
29.

Legg-Calvé-Perthes disease.

Leroux J, Abu Amara S, Lechevallier J.

Orthop Traumatol Surg Res. 2018 Feb;104(1S):S107-S112. doi: 10.1016/j.otsr.2017.04.012. Epub 2017 Nov 16. Review.

30.

Editorial: Drug Delivery: Too Much Complexity, Not Enough Reproducibility?

Leroux JC.

Angew Chem Int Ed Engl. 2017 Nov 27;56(48):15170-15171. doi: 10.1002/anie.201709002. Epub 2017 Oct 2.

PMID:
28967701
31.

Liposome-supported enzymatic peritoneal dialysis.

Pratsinis A, Zuercher S, Forster V, Fischer EJ, Luciani P, Leroux JC.

Biomaterials. 2017 Nov;145:128-137. doi: 10.1016/j.biomaterials.2017.08.016. Epub 2017 Aug 14.

PMID:
28858719
32.

Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology.

Pawar S, Ungricht R, Tiefenboeck P, Leroux JC, Kutay U.

Elife. 2017 Aug 14;6. pii: e28202. doi: 10.7554/eLife.28202.

33.

Microinjection for the ex Vivo Modification of Cells with Artificial Organelles.

Tiefenboeck P, Kim JA, Trunk F, Eicher T, Russo E, Teijeira A, Halin C, Leroux JC.

ACS Nano. 2017 Aug 22;11(8):7758-7769. doi: 10.1021/acsnano.7b01404. Epub 2017 Aug 11.

PMID:
28777538
34.

Gastroresistant oral peptide for fluorescence imaging of colonic inflammation.

Luciani P, Estella-Hermoso de Mendoza A, Casalini T, Lang S, Atrott K, Spalinger MR, Pratsinis A, Sobek J, Frey-Wagner I, Schumacher J, Leroux JC, Rogler G.

J Control Release. 2017 Sep 28;262:118-126. doi: 10.1016/j.jconrel.2017.07.024. Epub 2017 Jul 19.

PMID:
28734901
35.

Comment on "A Liposomal System Capable of Generating CO2 Bubbles to Induce Transient Cavitation, Lysosomal Rupturing and Cell Necrosis".

Tiefenboeck P, Kim JA, Trunk F, Leroux JC.

Angew Chem Int Ed Engl. 2017 Sep 18;56(39):11686-11689. doi: 10.1002/anie.201703740. Epub 2017 Jul 6. No abstract available.

PMID:
28681973
36.

Exploiting the Evolutionary Relationship between Malarial Parasites and Plants To Develop New Herbicides.

Corral MG, Leroux J, Tresch S, Newton T, Stubbs KA, Mylne JS.

Angew Chem Int Ed Engl. 2017 Aug 7;56(33):9881-9885. doi: 10.1002/anie.201705400. Epub 2017 Jul 12.

PMID:
28654179
37.

Ratiometric Fluorescent Probes for the Detection of Reactive Oxygen Species.

Andina D, Leroux JC, Luciani P.

Chemistry. 2017 Oct 4;23(55):13549-13573. doi: 10.1002/chem.201702458. Epub 2017 Aug 21. Review.

PMID:
28561437
38.

Five-year outcomes of the First Distal Uninstrumented Vertebra after posterior fusion for Adolescent Idiopathic Scoliosis Lenke 1 or 2.

Clément JL, Solla F, Tran A, Morin C, Lakhal W, Sales de Gauzy J, Leroux J, Gennari JM, Parent FH, Kreichati G, Wolf S, Obeid I.

Orthop Traumatol Surg Res. 2017 Sep;103(5):727-731. doi: 10.1016/j.otsr.2017.04.006. Epub 2017 May 27.

39.

Letter to the Editor - The implications of the professionalization of health promotion in Canada: a response to JR Graham's letter to the editor.

Gagné T, Lapalme J, Leroux J.

Health Promot Chronic Dis Prev Can. 2017 May;37(5):172-173. doi: 10.24095/hpcdp.37.5.05. English, French.

40.

Releasable and traceless PEGylation of arginine-rich antimicrobial peptides.

Gong Y, Andina D, Nahar S, Leroux JC, Gauthier MA.

Chem Sci. 2017 May 1;8(5):4082-4086. doi: 10.1039/c7sc00770a. Epub 2017 Mar 30.

41.

Prolonged circulation and increased tumor accumulation of liposomal vincristine in a mouse model of rhabdomyosarcoma.

Roveri M, Pfohl A, Jaaks P, Alijaj N, Leroux JC, Luciani P, Bernasconi M.

Nanomedicine (Lond). 2017 May;12(10):1135-1151. doi: 10.2217/nnm-2017-0430. Epub 2017 Apr 27.

PMID:
28447920
42.

Herbicidal properties of antimalarial drugs.

Corral MG, Leroux J, Stubbs KA, Mylne JS.

Sci Rep. 2017 Mar 31;7:45871. doi: 10.1038/srep45871.

43.

Characterization of Calcium Phosphate Nanoparticles Based on a PEGylated Chelator for Gene Delivery.

Huang X, Andina D, Ge J, Labarre A, Leroux JC, Castagner B.

ACS Appl Mater Interfaces. 2017 Mar 29;9(12):10435-10445. doi: 10.1021/acsami.6b15925. Epub 2017 Mar 14.

PMID:
28266206
44.

Development of a Modular Ratiometric Fluorescent Probe for the Detection of Extracellular Superoxide.

Andina D, Brambilla D, Munzinger N, Frei J, Zivko C, Leroux JC, Luciani P.

Chemistry. 2017 Apr 6;23(20):4765-4769. doi: 10.1002/chem.201700563. Epub 2017 Mar 23.

PMID:
28256754
45.

[Slipped capital femoral epiphysis].

Klein C, Haraux E, Leroux J, Gouron R.

Arch Pediatr. 2017 Mar;24(3):301-305. doi: 10.1016/j.arcped.2016.12.011. Epub 2017 Feb 1. Review. French.

PMID:
28161230
46.

Drug Delivery Research for the Future: Expanding the Nano Horizons and Beyond.

Mitragotri S, Lammers T, Bae YH, Schwendeman S, De Smedt S, Leroux JC, Peer D, Kwon IC, Harashima H, Kikuchi A, Oh YK, Torchilin V, Hennink W, Hanes J, Park K.

J Control Release. 2017 Jan 28;246:183-184. doi: 10.1016/j.jconrel.2017.01.011. No abstract available.

PMID:
28110715
47.

Quantitative measurement of lymphatic function in mice by noninvasive near-infrared imaging of a peripheral vein.

Proulx ST, Ma Q, Andina D, Leroux JC, Detmar M.

JCI Insight. 2017 Jan 12;2(1):e90861. doi: 10.1172/jci.insight.90861.

48.

Well-Defined Multivalent Ligands for Hepatocytes Targeting via Asialoglycoprotein Receptor.

Huang X, Leroux JC, Castagner B.

Bioconjug Chem. 2017 Feb 15;28(2):283-295. doi: 10.1021/acs.bioconjchem.6b00651. Epub 2016 Dec 27. Review.

PMID:
27966887
49.

Surgical treatment using The Unit Rod in children with neuromuscular scoliosis.

Nedelcu T, Georgescu I, Leroux J, Lechevallier J, Barbilian A, Tuhar I.

J Med Life. 2016 Oct-Dec;9(4):399-407.

50.

Targeting Nanocarriers with Anisamide: Fact or Artifact?

Dasargyri A, Kümin CD, Leroux JC.

Adv Mater. 2017 Feb;29(7). doi: 10.1002/adma.201603451. Epub 2016 Nov 25. Review.

PMID:
27885719

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