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Items: 1 to 50 of 517

1.

3D printing of a wearable personalized oral delivery device: A first-in-human study.

Liang K, Carmone S, Brambilla D, Leroux JC.

Sci Adv. 2018 May 9;4(5):eaat2544. doi: 10.1126/sciadv.aat2544. eCollection 2018 May.

2.

Pharmacokinetics of lipid-drug conjugates loaded into liposomes.

Signorell RD, Luciani P, Brambilla D, Leroux JC.

Eur J Pharm Biopharm. 2018 Jul;128:188-199. doi: 10.1016/j.ejpb.2018.04.003. Epub 2018 Apr 18. Review.

PMID:
29678733
3.

The novelty bubble.

Leroux JC.

J Control Release. 2018 May 28;278:140-141. doi: 10.1016/j.jconrel.2018.03.032. Epub 2018 Mar 28. No abstract available.

PMID:
29604310
4.

Liposome-supported peritoneal dialysis in the treatment of severe hyperammonemia: An investigation on potential interactions.

Giacalone G, Matoori S, Agostoni V, Forster V, Kabbaj M, Eggenschwiler S, Lussi M, De Gottardi A, Zamboni N, Leroux JC.

J Control Release. 2018 May 28;278:57-65. doi: 10.1016/j.jconrel.2018.03.030. Epub 2018 Mar 27.

PMID:
29601930
5.

A herbicide structure-activity analysis of the antimalarial lead compound MMV007978 against Arabidopsis thaliana.

Corral MG, Leroux J, Tresch S, Newton T, Stubbs KA, Mylne JS.

Pest Manag Sci. 2018 Jul;74(7):1558-1563. doi: 10.1002/ps.4872. Epub 2018 Mar 5.

PMID:
29377434
6.

Structural properties and gene-silencing activity of chemically modified DNA-RNA hybrids with parallel orientation.

Habibian M, Yahyaee-Anzahaee M, Lucic M, Moroz E, Martín-Pintado N, Di Giovanni LD, Leroux JC, Hall J, González C, Damha MJ.

Nucleic Acids Res. 2018 Feb 28;46(4):1614-1623. doi: 10.1093/nar/gky024.

7.

Peritoneal dialysis beyond kidney failure?

Pratsinis A, Devuyst O, Leroux JC.

J Control Release. 2018 Jul 28;282:3-12. doi: 10.1016/j.jconrel.2018.01.017. Epub 2018 Jan 31.

PMID:
29360477
8.

FAM46A mutations are responsible for autosomal recessive osteogenesis imperfecta.

Doyard M, Bacrot S, Huber C, Di Rocco M, Goldenberg A, Aglan MS, Brunelle P, Temtamy S, Michot C, Otaify GA, Haudry C, Castanet M, Leroux J, Bonnefont JP, Munnich A, Baujat G, Lapunzina P, Monnot S, Ruiz-Perez VL, Cormier-Daire V.

J Med Genet. 2018 Apr;55(4):278-284. doi: 10.1136/jmedgenet-2017-104999. Epub 2018 Jan 22.

PMID:
29358272
9.

Preparation of PEGylated liposomes incorporating lipophilic lomeguatrib derivatives for the sensitization of chemo-resistant gliomas.

Signorell RD, Papachristodoulou A, Xiao J, Arpagaus B, Casalini T, Grandjean J, Thamm J, Steiniger F, Luciani P, Brambilla D, Werner B, Martin E, Weller M, Roth P, Leroux JC.

Int J Pharm. 2018 Jan 30;536(1):388-396. doi: 10.1016/j.ijpharm.2017.11.070. Epub 2017 Dec 2.

PMID:
29198811
10.

Enzyme-Mimetic Antioxidant Luminescent Nanoparticles for Highly Sensitive Hydrogen Peroxide Biosensing.

Pratsinis A, Kelesidis GA, Zuercher S, Krumeich F, Bolisetty S, Mezzenga R, Leroux JC, Sotiriou GA.

ACS Nano. 2017 Dec 26;11(12):12210-12218. doi: 10.1021/acsnano.7b05518. Epub 2017 Dec 4.

PMID:
29182310
11.

Legg-Calvé-Perthes disease.

Leroux J, Abu Amara S, Lechevallier J.

Orthop Traumatol Surg Res. 2018 Feb;104(1S):S107-S112. doi: 10.1016/j.otsr.2017.04.012. Epub 2017 Nov 16. Review.

PMID:
29155310
12.

Editorial: Drug Delivery: Too Much Complexity, Not Enough Reproducibility?

Leroux JC.

Angew Chem Int Ed Engl. 2017 Nov 27;56(48):15170-15171. doi: 10.1002/anie.201709002. Epub 2017 Oct 2.

PMID:
28967701
13.

Liposome-supported enzymatic peritoneal dialysis.

Pratsinis A, Zuercher S, Forster V, Fischer EJ, Luciani P, Leroux JC.

Biomaterials. 2017 Nov;145:128-137. doi: 10.1016/j.biomaterials.2017.08.016. Epub 2017 Aug 14.

PMID:
28858719
14.

Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology.

Pawar S, Ungricht R, Tiefenboeck P, Leroux JC, Kutay U.

Elife. 2017 Aug 14;6. pii: e28202. doi: 10.7554/eLife.28202.

15.

Microinjection for the ex Vivo Modification of Cells with Artificial Organelles.

Tiefenboeck P, Kim JA, Trunk F, Eicher T, Russo E, Teijeira A, Halin C, Leroux JC.

ACS Nano. 2017 Aug 22;11(8):7758-7769. doi: 10.1021/acsnano.7b01404. Epub 2017 Aug 11.

PMID:
28777538
16.

Gastroresistant oral peptide for fluorescence imaging of colonic inflammation.

Luciani P, Estella-Hermoso de Mendoza A, Casalini T, Lang S, Atrott K, Spalinger MR, Pratsinis A, Sobek J, Frey-Wagner I, Schumacher J, Leroux JC, Rogler G.

J Control Release. 2017 Sep 28;262:118-126. doi: 10.1016/j.jconrel.2017.07.024. Epub 2017 Jul 19.

PMID:
28734901
17.

Comment on "A Liposomal System Capable of Generating CO2 Bubbles to Induce Transient Cavitation, Lysosomal Rupturing and Cell Necrosis".

Tiefenboeck P, Kim JA, Trunk F, Leroux JC.

Angew Chem Int Ed Engl. 2017 Sep 18;56(39):11686-11689. doi: 10.1002/anie.201703740. Epub 2017 Jul 6. No abstract available.

PMID:
28681973
18.

Exploiting the Evolutionary Relationship between Malarial Parasites and Plants To Develop New Herbicides.

Corral MG, Leroux J, Tresch S, Newton T, Stubbs KA, Mylne JS.

Angew Chem Int Ed Engl. 2017 Aug 7;56(33):9881-9885. doi: 10.1002/anie.201705400. Epub 2017 Jul 12.

PMID:
28654179
19.

Ratiometric Fluorescent Probes for the Detection of Reactive Oxygen Species.

Andina D, Leroux JC, Luciani P.

Chemistry. 2017 Oct 4;23(55):13549-13573. doi: 10.1002/chem.201702458. Epub 2017 Aug 21. Review.

PMID:
28561437
20.

Five-year outcomes of the First Distal Uninstrumented Vertebra after posterior fusion for Adolescent Idiopathic Scoliosis Lenke 1 or 2.

Clément JL, Solla F, Tran A, Morin C, Lakhal W, Sales de Gauzy J, Leroux J, Gennari JM, Parent FH, Kreichati G, Wolf S, Obeid I.

Orthop Traumatol Surg Res. 2017 Sep;103(5):727-731. doi: 10.1016/j.otsr.2017.04.006. Epub 2017 May 27.

PMID:
28554809
21.

Letter to the Editor - The implications of the professionalization of health promotion in Canada: a response to JR Graham's letter to the editor.

Gagné T, Lapalme J, Leroux J.

Health Promot Chronic Dis Prev Can. 2017 May;37(5):172-173. doi: 10.24095/hpcdp.37.5.05. English, French.

22.

Prolonged circulation and increased tumor accumulation of liposomal vincristine in a mouse model of rhabdomyosarcoma.

Roveri M, Pfohl A, Jaaks P, Alijaj N, Leroux JC, Luciani P, Bernasconi M.

Nanomedicine (Lond). 2017 May;12(10):1135-1151. doi: 10.2217/nnm-2017-0430. Epub 2017 Apr 27.

PMID:
28447920
23.

Herbicidal properties of antimalarial drugs.

Corral MG, Leroux J, Stubbs KA, Mylne JS.

Sci Rep. 2017 Mar 31;7:45871. doi: 10.1038/srep45871.

24.

Characterization of Calcium Phosphate Nanoparticles Based on a PEGylated Chelator for Gene Delivery.

Huang X, Andina D, Ge J, Labarre A, Leroux JC, Castagner B.

ACS Appl Mater Interfaces. 2017 Mar 29;9(12):10435-10445. doi: 10.1021/acsami.6b15925. Epub 2017 Mar 14.

PMID:
28266206
25.

Development of a Modular Ratiometric Fluorescent Probe for the Detection of Extracellular Superoxide.

Andina D, Brambilla D, Munzinger N, Frei J, Zivko C, Leroux JC, Luciani P.

Chemistry. 2017 Apr 6;23(20):4765-4769. doi: 10.1002/chem.201700563. Epub 2017 Mar 23.

PMID:
28256754
26.

[Slipped capital femoral epiphysis].

Klein C, Haraux E, Leroux J, Gouron R.

Arch Pediatr. 2017 Mar;24(3):301-305. doi: 10.1016/j.arcped.2016.12.011. Epub 2017 Feb 1. Review. French.

PMID:
28161230
27.

Drug Delivery Research for the Future: Expanding the Nano Horizons and Beyond.

Mitragotri S, Lammers T, Bae YH, Schwendeman S, De Smedt S, Leroux JC, Peer D, Kwon IC, Harashima H, Kikuchi A, Oh YK, Torchilin V, Hennink W, Hanes J, Park K.

J Control Release. 2017 Jan 28;246:183-184. doi: 10.1016/j.jconrel.2017.01.011. No abstract available.

PMID:
28110715
28.

Quantitative measurement of lymphatic function in mice by noninvasive near-infrared imaging of a peripheral vein.

Proulx ST, Ma Q, Andina D, Leroux JC, Detmar M.

JCI Insight. 2017 Jan 12;2(1):e90861. doi: 10.1172/jci.insight.90861.

29.

Well-Defined Multivalent Ligands for Hepatocytes Targeting via Asialoglycoprotein Receptor.

Huang X, Leroux JC, Castagner B.

Bioconjug Chem. 2017 Feb 15;28(2):283-295. doi: 10.1021/acs.bioconjchem.6b00651. Epub 2016 Dec 27. Review.

PMID:
27966887
30.

Surgical treatment using The Unit Rod in children with neuromuscular scoliosis.

Nedelcu T, Georgescu I, Leroux J, Lechevallier J, Barbilian A, Tuhar I.

J Med Life. 2016 Oct-Dec;9(4):399-407.

31.

Targeting Nanocarriers with Anisamide: Fact or Artifact?

Dasargyri A, Kümin CD, Leroux JC.

Adv Mater. 2017 Feb;29(7). doi: 10.1002/adma.201603451. Epub 2016 Nov 25. Review.

PMID:
27885719
32.

Serum-Stable, Long-Circulating, pH-Sensitive PEGylated Liposomes.

Bertrand N, Simard P, Leroux JC.

Methods Mol Biol. 2017;1522:193-207.

PMID:
27837540
33.

In Vitro and In Vivo Evaluation of PEGylated Layer-by-Layer Polyelectrolyte-Coated Paclitaxel Nanocrystals.

Polomska A, Gauthier MA, Leroux JC.

Small. 2017 Jan;13(2). doi: 10.1002/smll.201602066. Epub 2016 Oct 17.

PMID:
27748999
34.

Presumed LRP1-targeting transport peptide delivers β-secretase inhibitor to neurons in vitro with limited efficiency.

Kim JA, Casalini T, Brambilla D, Leroux JC.

Sci Rep. 2016 Sep 29;6:34297. doi: 10.1038/srep34297.

35.

Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells.

Moroz E, Lee SH, Yamada K, Halloy F, Martínez-Montero S, Jahns H, Hall J, Damha MJ, Castagner B, Leroux JC.

Mol Ther Nucleic Acids. 2016 Sep 20;5(9):e364. doi: 10.1038/mtna.2016.69.

36.

Quantitative analysis of the deposited nanoparticle dose on cell cultures by optical absorption spectroscopy.

Spyrogianni A, Herrmann IK, Lucas MS, Leroux JC, Sotiriou GA.

Nanomedicine (Lond). 2016 Oct;11(19):2483-96. doi: 10.2217/nnm-2016-0243. Epub 2016 Sep 13.

PMID:
27622851
37.

Layer-by-Layer Coating of Solid Drug Cores: A Versatile Method to Improve Stability, Control Release and Tune Surface Properties.

Polomska A, Leroux JC, Brambilla D.

Macromol Biosci. 2017 Jan;17(1). doi: 10.1002/mabi.201600228. Epub 2016 Aug 29. Review.

PMID:
27569374
38.

Cervical myelopathy involving os odontoideum and retro-odontoid cyst treated with Harms C1-C2 arthrodesis.

Le Pape S, Gauthé R, Latrobe C, Leroux J, Roussignol X, Ould-Slimane M.

Orthop Traumatol Surg Res. 2016 Oct;102(6):817-20. doi: 10.1016/j.otsr.2016.06.008. Epub 2016 Jul 27.

39.

Regulation of lymphangiogenesis in the diaphragm by macrophages and VEGFR-3 signaling.

Ochsenbein AM, Karaman S, Proulx ST, Goldmann R, Chittazhathu J, Dasargyri A, Chong C, Leroux JC, Stanley ER, Detmar M.

Angiogenesis. 2016 Oct;19(4):513-24. doi: 10.1007/s10456-016-9523-8. Epub 2016 Jul 27.

40.

Protein-altering MYH3 variants are associated with a spectrum of phenotypes extending to spondylocarpotarsal synostosis syndrome.

Carapito R, Goldenberg A, Paul N, Pichot A, David A, Hamel A, Dumant-Forest C, Leroux J, Ory B, Isidor B, Bahram S.

Eur J Hum Genet. 2016 Dec;24(12):1746-1751. doi: 10.1038/ejhg.2016.84. Epub 2016 Jul 6.

41.

A Chiral Phosphoramidite Reagent for the Synthesis of Inositol Phosphates.

Durantie E, Huwiler S, Leroux JC, Castagner B.

Org Lett. 2016 Jul 1;18(13):3162-5. doi: 10.1021/acs.orglett.6b01374. Epub 2016 Jun 22.

PMID:
27332109
42.

[Are C2 pedicles always screwable? Calibration and planning with a pedicle-lamina angle].

Le Pape S, Gauthe R, Latrobe C, Cantogrel P, Proust F, Leroux J, Ould-Slimane M.

Neurochirurgie. 2016 Aug;62(4):209-12. doi: 10.1016/j.neuchi.2015.10.011. Epub 2016 May 25. French.

PMID:
27236736
43.

Preparation of PEGylated chelator-stabilized calcium phosphate nanoparticles for liver-targeted delivery of nucleic acid.

Huang X, Andina D, Leroux JC, Castagner B.

J Control Release. 2015 Sep 10;213:e116. doi: 10.1016/j.jconrel.2015.05.195. Epub 2015 Aug 19. No abstract available.

PMID:
27005053
44.

Oral prodrug strategy for poorly soluble drugs.

Sun T, Morger A, Castagner B, Leroux JC.

J Control Release. 2015 Sep 10;213:e102. doi: 10.1016/j.jconrel.2015.05.171. Epub 2015 Aug 19. No abstract available.

PMID:
27005028
45.

In vivo visualization and quantification of collecting lymphatic vessel contractility using near-infrared imaging.

Chong C, Scholkmann F, Bachmann SB, Luciani P, Leroux JC, Detmar M, Proulx ST.

Sci Rep. 2016 Mar 10;6:22930. doi: 10.1038/srep22930.

46.

Polymer-coated pH-responsive high-density lipoproteins.

Kim H, Okamoto H, Felber AE, Polomska A, Morone N, Heuser JE, Leroux JC, Murakami T.

J Control Release. 2016 Apr 28;228:132-140. doi: 10.1016/j.jconrel.2016.03.005. Epub 2016 Mar 6.

PMID:
26959846
47.

Corrigendum: Sustained gastrointestinal activity of dendronized polymer-enzyme conjugates.

Fuhrmann G, Grotzky A, Lukić R, Matoori S, Luciani P, Yu H, Zhang B, Walde P, Schlüter AD, Gauthier MA, Leroux JC.

Nat Chem. 2016 Mar;8(3):281. doi: 10.1038/nchem.2458. No abstract available.

PMID:
26892564
48.

Oral delivery of macromolecular drugs: Where we are after almost 100years of attempts.

Moroz E, Matoori S, Leroux JC.

Adv Drug Deliv Rev. 2016 Jun 1;101:108-121. doi: 10.1016/j.addr.2016.01.010. Epub 2016 Jan 27. Review.

PMID:
26826437
49.

Findings questioning the involvement of Sigma-1 receptor in the uptake of anisamide-decorated particles.

Dasargyri A, Hervella P, Christiansen A, Proulx ST, Detmar M, Leroux JC.

J Control Release. 2016 Feb 28;224:229-238. doi: 10.1016/j.jconrel.2016.01.021. Epub 2016 Jan 13.

PMID:
26774218
50.

Microneedles for the Noninvasive Structural and Functional Assessment of Dermal Lymphatic Vessels.

Brambilla D, Proulx ST, Marschalkova P, Detmar M, Leroux JC.

Small. 2016 Feb 24;12(8):1053-61. doi: 10.1002/smll.201503093. Epub 2016 Jan 4.

PMID:
26727610

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