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Items: 23

1.

RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure.

Solomon O, Di Segni A, Cesarkas K, Porath HT, Marcu-Malina V, Mizrahi O, Stern-Ginossar N, Kol N, Farage-Barhom S, Glick-Saar E, Lerenthal Y, Levanon EY, Amariglio N, Unger R, Goldstein I, Eyal E, Rechavi G.

Nat Commun. 2017 Nov 13;8(1):1440. doi: 10.1038/s41467-017-01458-8.

2.

Eukaryotic initiation factor 2α--a downstream effector of mammalian target of rapamycin--modulates DNA repair and cancer response to treatment.

Tuval-Kochen L, Paglin S, Keshet G, Lerenthal Y, Nakar C, Golani T, Toren A, Yahalom J, Pfeffer R, Lawrence Y.

PLoS One. 2013 Oct 25;8(10):e77260. doi: 10.1371/journal.pone.0077260. eCollection 2013.

3.

Novel SMARCAL1 bi-allelic mutations associated with a chromosomal breakage phenotype in a severe SIOD patient.

Simon AJ, Lev A, Jeison M, Borochowitz ZU, Korn D, Lerenthal Y, Somech R.

J Clin Immunol. 2014 Jan;34(1):76-83. doi: 10.1007/s10875-013-9957-3. Epub 2013 Nov 7.

PMID:
24197801
4.

Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease.

Harari-Steinberg O, Metsuyanim S, Omer D, Gnatek Y, Gershon R, Pri-Chen S, Ozdemir DD, Lerenthal Y, Noiman T, Ben-Hur H, Vaknin Z, Schneider DF, Aronow BJ, Goldstein RS, Hohenstein P, Dekel B.

EMBO Mol Med. 2013 Oct;5(10):1556-68. doi: 10.1002/emmm.201201584. Epub 2013 Sep 2.

5.

Acute lymphoblastic leukemia in early childhood as the presenting sign of ataxia-telangiectasia variant.

Bielorai B, Fisher T, Waldman D, Lerenthal Y, Nissenkorn A, Tohami T, Marek D, Amariglio N, Toren A.

Pediatr Hematol Oncol. 2013 Sep;30(6):574-82. doi: 10.3109/08880018.2013.777949. Epub 2013 Mar 19.

PMID:
23509889
6.

Ras oncoproteins transfer from melanoma cells to T cells and modulate their effector functions.

Vernitsky H, Rechavi O, Rainy N, Besser MJ, Nagar M, Schachter J, Lerenthal Y, Ehrlich M, Kloog Y, Goldstein I.

J Immunol. 2012 Nov 1;189(9):4361-70. doi: 10.4049/jimmunol.1200019. Epub 2012 Oct 1.

7.

Involvement of the nuclear proteasome activator PA28γ in the cellular response to DNA double-strand breaks.

Levy-Barda A, Lerenthal Y, Davis AJ, Chung YM, Essers J, Shao Z, van Vliet N, Chen DJ, Hu MC, Kanaar R, Ziv Y, Shiloh Y.

Cell Cycle. 2011 Dec 15;10(24):4300-10. doi: 10.4161/cc.10.24.18642. Epub 2011 Dec 15.

8.

Transcriptional modulation induced by ionizing radiation: p53 remains a central player.

Rashi-Elkeles S, Elkon R, Shavit S, Lerenthal Y, Linhart C, Kupershtein A, Amariglio N, Rechavi G, Shamir R, Shiloh Y.

Mol Oncol. 2011 Aug;5(4):336-48. doi: 10.1016/j.molonc.2011.06.004. Epub 2011 Jul 7. Review.

9.

ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control.

Gatei M, Jakob B, Chen P, Kijas AW, Becherel OJ, Gueven N, Birrell G, Lee JH, Paull TT, Lerenthal Y, Fazry S, Taucher-Scholz G, Kalb R, Schindler D, Waltes R, Dörk T, Lavin MF.

J Biol Chem. 2011 Sep 9;286(36):31542-56. doi: 10.1074/jbc.M111.258152. Epub 2011 Jul 14.

10.

ATM-mediated phosphorylation of polynucleotide kinase/phosphatase is required for effective DNA double-strand break repair.

Segal-Raz H, Mass G, Baranes-Bachar K, Lerenthal Y, Wang SY, Chung YM, Ziv-Lehrman S, Ström CE, Helleday T, Hu MC, Chen DJ, Shiloh Y.

EMBO Rep. 2011 Jul 1;12(7):713-9. doi: 10.1038/embor.2011.96.

11.

Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.

Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang SY, Eppink B, Chung YM, Shalev G, Shema E, Shkedy D, Smorodinsky NI, van Vliet N, Kuster B, Mann M, Ciechanover A, Dahm-Daphi J, Kanaar R, Hu MC, Chen DJ, Oren M, Shiloh Y.

Mol Cell. 2011 Mar 4;41(5):529-42. doi: 10.1016/j.molcel.2011.02.015.

12.

Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response.

Salton M, Lerenthal Y, Wang SY, Chen DJ, Shiloh Y.

Cell Cycle. 2010 Apr 15;9(8):1568-76. Epub 2010 Apr 15.

PMID:
20421735
13.

Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder.

Waltes R, Kalb R, Gatei M, Kijas AW, Stumm M, Sobeck A, Wieland B, Varon R, Lerenthal Y, Lavin MF, Schindler D, Dörk T.

Am J Hum Genet. 2009 May;84(5):605-16. doi: 10.1016/j.ajhg.2009.04.010. Epub 2009 Apr 30.

14.

ATM kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells.

Stagni V, di Bari MG, Cursi S, Condò I, Cencioni MT, Testi R, Lerenthal Y, Cundari E, Barilà D.

Blood. 2008 Jan 15;111(2):829-37. Epub 2007 Oct 11.

15.

Regulation of transcription of the RNA splicing factor hSlu7 by Elk-1 and Sp1 affects alternative splicing.

Alberstein M, Amit M, Vaknin K, O'Donnell A, Farhy C, Lerenthal Y, Shomron N, Shaham O, Sharrocks AD, Ashery-Padan R, Ast G.

RNA. 2007 Nov;13(11):1988-99. Epub 2007 Sep 5.

16.

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ.

Science. 2007 May 25;316(5828):1160-6.

17.

Insulin-like growth factor-I controls BRCA1 gene expression through activation of transcription factor Sp1.

Maor S, Papa MZ, Yarden RI, Friedman E, Lerenthal Y, Lee SW, Mayer D, Werner H.

Horm Metab Res. 2007 Mar;39(3):179-85.

PMID:
17373631
18.

Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.

Chen BP, Uematsu N, Kobayashi J, Lerenthal Y, Krempler A, Yajima H, Löbrich M, Shiloh Y, Chen DJ.

J Biol Chem. 2007 Mar 2;282(9):6582-7. Epub 2006 Dec 21.

19.

Condensin I recruitment and uneven chromatin condensation precede mitotic cell death in response to DNA damage.

Blank M, Lerenthal Y, Mittelman L, Shiloh Y.

J Cell Biol. 2006 Jul 17;174(2):195-206.

20.

Proapoptotic BID is an ATM effector in the DNA-damage response.

Kamer I, Sarig R, Zaltsman Y, Niv H, Oberkovitz G, Regev L, Haimovich G, Lerenthal Y, Marcellus RC, Gross A.

Cell. 2005 Aug 26;122(4):593-603.

21.

Dissection of a DNA-damage-induced transcriptional network using a combination of microarrays, RNA interference and computational promoter analysis.

Elkon R, Rashi-Elkeles S, Lerenthal Y, Linhart C, Tenne T, Amariglio N, Rechavi G, Shamir R, Shiloh Y.

Genome Biol. 2005;6(5):R43. Epub 2005 Apr 13.

22.

Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention.

Lukas C, Melander F, Stucki M, Falck J, Bekker-Jensen S, Goldberg M, Lerenthal Y, Jackson SP, Bartek J, Lukas J.

EMBO J. 2004 Jul 7;23(13):2674-83. Epub 2004 Jun 17.

23.

Requirement of the MRN complex for ATM activation by DNA damage.

Uziel T, Lerenthal Y, Moyal L, Andegeko Y, Mittelman L, Shiloh Y.

EMBO J. 2003 Oct 15;22(20):5612-21.

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