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Items: 19

1.

PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells.

Agrawal Singh S, Lerdrup M, Gomes AR, van de Werken HJ, Vilstrup Johansen J, Andersson R, Sandelin A, Helin K, Hansen K.

Elife. 2019 Jan 23;8. pii: e40364. doi: 10.7554/eLife.40364.

2.

Proteogenomic Characterization of Patient-Derived Xenografts Highlights the Role of REST in Neuroendocrine Differentiation of Castration-Resistant Prostate Cancer.

Flores-Morales A, Bergmann TB, Lavallee C, Batth TS, Lin D, Lerdrup M, Friis S, Bartels A, Kristensen G, Krzyzanowska A, Xue H, Fazli L, Hansen KH, Røder MA, Brasso K, Moreira JM, Bjartell A, Wang Y, Olsen JV, Collins CC, Iglesias-Gato D.

Clin Cancer Res. 2019 Jan 15;25(2):595-608. doi: 10.1158/1078-0432.CCR-18-0729. Epub 2018 Oct 1.

PMID:
30274982
3.

Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing.

Shoaib M, Walter D, Gillespie PJ, Izard F, Fahrenkrog B, Lleres D, Lerdrup M, Johansen JV, Hansen K, Julien E, Blow JJ, Sørensen CS.

Nat Commun. 2018 Sep 12;9(1):3704. doi: 10.1038/s41467-018-06066-8.

4.

Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia.

Göllner S, Oellerich T, Agrawal-Singh S, Schenk T, Klein HU, Rohde C, Pabst C, Sauer T, Lerdrup M, Tavor S, Stölzel F, Herold S, Ehninger G, Köhler G, Pan KT, Urlaub H, Serve H, Dugas M, Spiekermann K, Vick B, Jeremias I, Berdel WE, Hansen K, Zelent A, Wickenhauser C, Müller LP, Thiede C, Müller-Tidow C.

Nat Med. 2017 Jan;23(1):69-78. doi: 10.1038/nm.4247. Epub 2016 Dec 12.

PMID:
27941792
5.

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

Dahl JA, Jung I, Aanes H, Greggains GD, Manaf A, Lerdrup M, Li G, Kuan S, Li B, Lee AY, Preissl S, Jermstad I, Haugen MH, Suganthan R, Bjørås M, Hansen K, Dalen KT, Fedorcsak P, Ren B, Klungland A.

Nature. 2016 Sep 22;537(7621):548-552. doi: 10.1038/nature19360. Epub 2016 Sep 14.

6.

An interactive environment for agile analysis and visualization of ChIP-sequencing data.

Lerdrup M, Johansen JV, Agrawal-Singh S, Hansen K.

Nat Struct Mol Biol. 2016 Apr;23(4):349-57. doi: 10.1038/nsmb.3180. Epub 2016 Feb 29.

PMID:
26926434
7.

β-Catenin Regulates Primitive Streak Induction through Collaborative Interactions with SMAD2/SMAD3 and OCT4.

Funa NS, Schachter KA, Lerdrup M, Ekberg J, Hess K, Dietrich N, Honoré C, Hansen K, Semb H.

Cell Stem Cell. 2015 Jun 4;16(6):639-52. doi: 10.1016/j.stem.2015.03.008. Epub 2015 Apr 23.

8.

Dopamine signaling leads to loss of Polycomb repression and aberrant gene activation in experimental parkinsonism.

Södersten E, Feyder M, Lerdrup M, Gomes AL, Kryh H, Spigolon G, Caboche J, Fisone G, Hansen K.

PLoS Genet. 2014 Sep 25;10(9):e1004574. doi: 10.1371/journal.pgen.1004574. eCollection 2014 Sep.

9.

DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding.

Schoofs T, Rohde C, Hebestreit K, Klein HU, Göllner S, Schulze I, Lerdrup M, Dietrich N, Agrawal-Singh S, Witten A, Stoll M, Lengfelder E, Hofmann WK, Schlenke P, Büchner T, Hansen K, Berdel WE, Rosenbauer F, Dugas M, Müller-Tidow C.

Blood. 2013 Jan 3;121(1):178-87. doi: 10.1182/blood-2012-08-448860. Epub 2012 Nov 14.

10.

REST-mediated recruitment of polycomb repressor complexes in mammalian cells.

Dietrich N, Lerdrup M, Landt E, Agrawal-Singh S, Bak M, Tommerup N, Rappsilber J, Södersten E, Hansen K.

PLoS Genet. 2012;8(3):e1002494. doi: 10.1371/journal.pgen.1002494. Epub 2012 Mar 1.

11.

Differential effects of EGFR ligands on endocytic sorting of the receptor.

Roepstorff K, Grandal MV, Henriksen L, Knudsen SL, Lerdrup M, Grøvdal L, Willumsen BM, van Deurs B.

Traffic. 2009 Aug;10(8):1115-27. doi: 10.1111/j.1600-0854.2009.00943.x. Epub 2009 May 19.

12.

A model for transmission of the H3K27me3 epigenetic mark.

Hansen KH, Bracken AP, Pasini D, Dietrich N, Gehani SS, Monrad A, Rappsilber J, Lerdrup M, Helin K.

Nat Cell Biol. 2008 Nov;10(11):1291-300. doi: 10.1038/ncb1787. Epub 2008 Oct 19. Erratum in: Nat Cell Biol. 2008 Dec;10(12):1484.

PMID:
18931660
13.

Endocytic downregulation of ErbB receptors: mechanisms and relevance in cancer.

Roepstorff K, Grøvdal L, Grandal M, Lerdrup M, van Deurs B.

Histochem Cell Biol. 2008 May;129(5):563-78. doi: 10.1007/s00418-008-0401-3. Epub 2008 Feb 21. Review.

14.

Endocytic down-regulation of ErbB2 is stimulated by cleavage of its C-terminus.

Lerdrup M, Bruun S, Grandal MV, Roepstorff K, Kristensen MM, Hommelgaard AM, van Deurs B.

Mol Biol Cell. 2007 Sep;18(9):3656-66. Epub 2007 Jul 11.

15.

Geldanamycin stimulates internalization of ErbB2 in a proteasome-dependent way.

Lerdrup M, Hommelgaard AM, Grandal M, van Deurs B.

J Cell Sci. 2006 Jan 1;119(Pt 1):85-95. Epub 2005 Dec 13.

16.

Depletion of the AP-1 repressor JDP2 induces cell death similar to apoptosis.

Lerdrup M, Holmberg C, Dietrich N, Shaulian E, Herdegen T, Jäättelä M, Kallunki T.

Biochim Biophys Acta. 2005 Aug 15;1745(1):29-37.

17.

Association with membrane protrusions makes ErbB2 an internalization-resistant receptor.

Hommelgaard AM, Lerdrup M, van Deurs B.

Mol Biol Cell. 2004 Apr;15(4):1557-67. Epub 2004 Jan 23.

18.

JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways.

Dietrich N, Thastrup J, Holmberg C, Gyrd-Hansen M, Fehrenbacher N, Lademann U, Lerdrup M, Herdegen T, Jäättelä M, Kallunki T.

Cell Death Differ. 2004 Mar;11(3):301-13.

19.

A novel specific role for I kappa B kinase complex-associated protein in cytosolic stress signaling.

Holmberg C, Katz S, Lerdrup M, Herdegen T, Jäättelä M, Aronheim A, Kallunki T.

J Biol Chem. 2002 Aug 30;277(35):31918-28. Epub 2002 Jun 10.

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