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Items: 44

1.

About the need to make computational models of biological macromolecules available and discoverable.

Abriata LA, Lepore R, Dal Peraro M.

Bioinformatics. 2020 Feb 13. pii: btaa086. doi: 10.1093/bioinformatics/btaa086. [Epub ahead of print]

PMID:
32053168
2.

Target highlights in CASP13: Experimental target structures through the eyes of their authors.

Lepore R, Kryshtafovych A, Alahuhta M, Veraszto HA, Bomble YJ, Bufton JC, Bullock AN, Caba C, Cao H, Davies OR, Desfosses A, Dunne M, Fidelis K, Goulding CW, Gurusaran M, Gutsche I, Harding CJ, Hartmann MD, Hayes CS, Joachimiak A, Leiman PG, Loppnau P, Lovering AL, Lunin VV, Michalska K, Mir-Sanchis I, Mitra AK, Moult J, Phillips GN Jr, Pinkas DM, Rice PA, Tong Y, Topf M, Walton JD, Schwede T.

Proteins. 2019 Dec;87(12):1037-1057. doi: 10.1002/prot.25805. Epub 2019 Sep 9.

3.

Insights on protein thermal stability: a graph representation of molecular interactions.

Miotto M, Olimpieri PP, Di Rienzo L, Ambrosetti F, Corsi P, Lepore R, Tartaglia GG, Milanetti E.

Bioinformatics. 2019 Aug 1;35(15):2569-2577. doi: 10.1093/bioinformatics/bty1011.

4.

Genome-wide RNA-seq analysis indicates that the DAG1 transcription factor promotes hypocotyl elongation acting on ABA, ethylene and auxin signaling.

Lorrai R, Gandolfi F, Boccaccini A, Ruta V, Possenti M, Tramontano A, Costantino P, Lepore R, Vittorioso P.

Sci Rep. 2018 Oct 26;8(1):15895. doi: 10.1038/s41598-018-34256-3.

5.

Modeling of Protein Tertiary and Quaternary Structures Based on Evolutionary Information.

Studer G, Tauriello G, Bienert S, Waterhouse AM, Bertoni M, Bordoli L, Schwede T, Lepore R.

Methods Mol Biol. 2019;1851:301-316. doi: 10.1007/978-1-4939-8736-8_17.

PMID:
30298405
6.

SWISS-MODEL: homology modelling of protein structures and complexes.

Waterhouse A, Bertoni M, Bienert S, Studer G, Tauriello G, Gumienny R, Heer FT, de Beer TAP, Rempfer C, Bordoli L, Lepore R, Schwede T.

Nucleic Acids Res. 2018 Jul 2;46(W1):W296-W303. doi: 10.1093/nar/gky427.

7.

PIGSPro: prediction of immunoGlobulin structures v2.

Lepore R, Olimpieri PP, Messih MA, Tramontano A.

Nucleic Acids Res. 2017 Jul 3;45(W1):W17-W23. doi: 10.1093/nar/gkx334.

8.

Superposition-free comparison and clustering of antibody binding sites: implications for the prediction of the nature of their antigen.

Di Rienzo L, Milanetti E, Lepore R, Olimpieri PP, Tramontano A.

Sci Rep. 2017 Mar 24;7:45053. doi: 10.1038/srep45053.

9.

Bilobate wandering spleen with doble torsion of the vascular pedicle. A case report.

Barra S, Lepore R, Cappabianca A, Barra F.

Ann Ital Chir. 2017 Mar 8;6. pii: S2239253X17026536.

PMID:
28272028
10.

An expanded evaluation of protein function prediction methods shows an improvement in accuracy.

Jiang Y, Oron TR, Clark WT, Bankapur AR, D'Andrea D, Lepore R, Funk CS, Kahanda I, Verspoor KM, Ben-Hur A, Koo da CE, Penfold-Brown D, Shasha D, Youngs N, Bonneau R, Lin A, Sahraeian SM, Martelli PL, Profiti G, Casadio R, Cao R, Zhong Z, Cheng J, Altenhoff A, Skunca N, Dessimoz C, Dogan T, Hakala K, Kaewphan S, Mehryary F, Salakoski T, Ginter F, Fang H, Smithers B, Oates M, Gough J, Törönen P, Koskinen P, Holm L, Chen CT, Hsu WL, Bryson K, Cozzetto D, Minneci F, Jones DT, Chapman S, Bkc D, Khan IK, Kihara D, Ofer D, Rappoport N, Stern A, Cibrian-Uhalte E, Denny P, Foulger RE, Hieta R, Legge D, Lovering RC, Magrane M, Melidoni AN, Mutowo-Meullenet P, Pichler K, Shypitsyna A, Li B, Zakeri P, ElShal S, Tranchevent LC, Das S, Dawson NL, Lee D, Lees JG, Sillitoe I, Bhat P, Nepusz T, Romero AE, Sasidharan R, Yang H, Paccanaro A, Gillis J, Sedeño-Cortés AE, Pavlidis P, Feng S, Cejuela JM, Goldberg T, Hamp T, Richter L, Salamov A, Gabaldon T, Marcet-Houben M, Supek F, Gong Q, Ning W, Zhou Y, Tian W, Falda M, Fontana P, Lavezzo E, Toppo S, Ferrari C, Giollo M, Piovesan D, Tosatto SC, Del Pozo A, Fernández JM, Maietta P, Valencia A, Tress ML, Benso A, Di Carlo S, Politano G, Savino A, Rehman HU, Re M, Mesiti M, Valentini G, Bargsten JW, van Dijk AD, Gemovic B, Glisic S, Perovic V, Veljkovic V, Veljkovic N, Almeida-E-Silva DC, Vencio RZ, Sharan M, Vogel J, Kansakar L, Zhang S, Vucetic S, Wang Z, Sternberg MJ, Wass MN, Huntley RP, Martin MJ, O'Donovan C, Robinson PN, Moreau Y, Tramontano A, Babbitt PC, Brenner SE, Linial M, Orengo CA, Rost B, Greene CS, Mooney SD, Friedberg I, Radivojac P.

Genome Biol. 2016 Sep 7;17(1):184. doi: 10.1186/s13059-016-1037-6.

11.

PepComposer: computational design of peptides binding to a given protein surface.

Obarska-Kosinska A, Iacoangeli A, Lepore R, Tramontano A.

Nucleic Acids Res. 2016 Jul 8;44(W1):W522-8. doi: 10.1093/nar/gkw366. Epub 2016 Apr 30.

12.

LoopIng: a template-based tool for predicting the structure of protein loops.

Messih MA, Lepore R, Tramontano A.

Bioinformatics. 2015 Dec 1;31(23):3767-72. doi: 10.1093/bioinformatics/btv438. Epub 2015 Aug 6.

13.

Multistep current signal in protein translocation through graphene nanopores.

Bonome EL, Lepore R, Raimondo D, Cecconi F, Tramontano A, Chinappi M.

J Phys Chem B. 2015 May 7;119(18):5815-23. doi: 10.1021/acs.jpcb.5b02172. Epub 2015 Apr 28.

PMID:
25866995
14.

Improving the accuracy of the structure prediction of the third hypervariable loop of the heavy chains of antibodies.

Messih MA, Lepore R, Marcatili P, Tramontano A.

Bioinformatics. 2014 Oct;30(19):2733-40. doi: 10.1093/bioinformatics/btu194. Epub 2014 Jun 13.

15.

TiPs: a database of therapeutic targets in pathogens and associated tools.

Lepore R, Tramontano A, Via A.

Bioinformatics. 2013 Jul 15;29(14):1821-2. doi: 10.1093/bioinformatics/btt289. Epub 2013 May 21.

16.

Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections.

Pillai DR, Lau R, Khairnar K, Lepore R, Via A, Staines HM, Krishna S.

Malar J. 2012 Apr 27;11:131. doi: 10.1186/1475-2875-11-131.

17.

Functional neuroimaging study in identical twin pairs discordant for regular cigarette smoking.

Lessov-Schlaggar CN, Lepore RL, Kristjansson SD, Schlaggar BL, Barnes KA, Petersen SE, Madden PA, Heath AC, Barch DM.

Addict Biol. 2013 Jan;18(1):98-108. doi: 10.1111/j.1369-1600.2012.00435.x. Epub 2012 Feb 17.

18.

Investigation of a potential mechanism for the inhibition of SmTGR by Auranofin and its implications for Plasmodium falciparum inhibition.

Caroli A, Simeoni S, Lepore R, Tramontano A, Via A.

Biochem Biophys Res Commun. 2012 Jan 6;417(1):576-81. doi: 10.1016/j.bbrc.2011.12.009. Epub 2011 Dec 8.

PMID:
22177949
19.

Identification of the Schistosoma mansoni molecular target for the antimalarial drug artemether.

Lepore R, Simeoni S, Raimondo D, Caroli A, Tramontano A, Via A.

J Chem Inf Model. 2011 Nov 28;51(11):3005-16. doi: 10.1021/ci2001764. Epub 2011 Oct 28.

PMID:
21995318
20.

[Ultrasound-guided trans-parietohepatic cholecystostomy in the critical patient: current indications].

Bongarzoni G, Bove A, Palone G, Scotti U, Pesciaioli C, Salvemini C, Danza C, Battagliola D, Lepore R, Corbellini L.

G Chir. 2001 Nov-Dec;22(11-12):395-400. Italian.

PMID:
11873638
21.

[Classification of varices with Doppler ultrasonography mapping. Clinical and hemodynamic correlation].

Di Nardo E, Colamussi G, Pitrelli N, Lepore R, Bongarzoni G.

Minerva Chir. 1998 Jul-Aug;53(7-8):615-8. Italian.

PMID:
9793350
22.

Amount and duration of alcohol intake as risk factors of symptomatic liver cirrhosis: a case-control study.

Corrao G, Aricò S, Lepore R, Valenti M, Torchio P, Galatola G, Tabone M, Di Orio F.

J Clin Epidemiol. 1993 Jul;46(7):601-7.

PMID:
8326344
23.

Gemfibrozil in CAPD patients.

De Vecchi A, Scalamogna A, Pini C, Castelnovo C, Colombini M, Lepore R.

Adv Perit Dial. 1991;7:240-2.

PMID:
1680435
24.
25.

Phosphodiesterase isozyme inhibition, activation of the cAMP system, and positive inotropy mediated by milrinone in isolated guinea pig cardiac muscle.

Silver PJ, Harris AL, Canniff PC, Lepore RE, Bentley RG, Hamel LT, Evans DB.

J Cardiovasc Pharmacol. 1989 Apr;13(4):530-40.

PMID:
2470989
26.

Inhibition of the low Km cyclic AMP phosphodiesterase and activation of the cyclic AMP system in vascular smooth muscle by milrinone.

Silver PJ, Lepore RE, O'Connor B, Lemp BM, Hamel LT, Bentley RG, Harris AL.

J Pharmacol Exp Ther. 1988 Oct;247(1):34-42.

PMID:
2845058
27.

Protein kinase C activity and reactivity to phorbol ester in vascular smooth muscle from spontaneously hypertensive rats (SHR) and normotensive Wistar Kyoto rats (WKY).

Silver PJ, Lepore RE, Cumiskey WR, Kiefer D, Harris AL.

Biochem Biophys Res Commun. 1988 Jul 15;154(1):272-7.

PMID:
3164997
28.

Changes induced by gemfibrozil on lipidic, coagulative and fibrinolytic pattern in patients with type IV hyperlipoproteinemia.

Avellone G, Di Garbo V, Panno AV, Cordova R, Lepore R, Strano A.

Int Angiol. 1988 Jul-Sep;7(3):270-7.

PMID:
3198979
29.

Evaluation of a sustained-release buccal nitroglycerin preparation in stable angina pectoris.

Grasso S, Pesciatini F, Ugolini C, Lepore R, Cerri B.

Int J Clin Pharmacol Res. 1988;8(2):131-7.

PMID:
3132428
30.

Mechanical anterior resection for carcinoma of the midrectum: long-term results.

Zannini G, Renda A, Lepore R, Coppola L, Landi R, D'Antonio M.

Int Surg. 1987 Jan-Mar;72(1):18-9.

PMID:
3596971
31.

[Instrumental follow-up of anterior mechanical resection].

Renda A, Sava M, Angelillo M, Lepore R, Coppola L, Landi R.

Minerva Chir. 1986 Dec 31;41(23-24):2037-9. Italian. No abstract available.

PMID:
3547175
32.

[Multicenter study on the therapeutic activity of buflomedil chlorhydrate in obliterative arteriopathies of the legs].

Allegra C, Andreozzi GM, Avellone G, Cospite M, Del Guercio R, Lepore R, Nuzzaci G, Pinto A, Romeo S.

Clin Ter. 1986 Oct 15;119(1):25-33. Italian. No abstract available.

PMID:
3539466
33.

Identification and characterization of substance P receptors on LRM55 glial cells.

Perrone MH, Lepore RD, Shain W.

J Pharmacol Exp Ther. 1986 Aug;238(2):389-95.

PMID:
2426440
34.

Activation of beta-adrenergic receptors stimulates release of an inhibitory transmitter from astrocytes.

Shain W, Madelian V, Martin DL, Kimelberg HK, Perrone M, Lepore R.

J Neurochem. 1986 Apr;46(4):1298-303.

PMID:
3005511
35.

Beta-receptor-stimulated and cyclic adenosine 3',5'-monophosphate-mediated taurine release from LRM55 glial cells.

Madelian V, Martin DL, Lepore R, Perrone M, Shain W.

J Neurosci. 1985 Dec;5(12):3154-60.

36.

Treatment of vasospastic angina pectoris at rest with nitroglycerin ointment: a short-term controlled study in the coronary care unit.

Salerno JA, Previtali M, Medici A, Chimienti M, Bramucci E, Lepore R, Specchia G, Bobba P.

Am J Cardiol. 1981 May;47(5):1128-33.

PMID:
6784566
37.

Follow-up results of surgical treatment in cancer of the colon.

Zannini G, Renda A, Lepore R, Sfarzo A, Angrisani P.

Int Surg. 1981 Apr-Jun;66(2):137-9. No abstract available.

PMID:
7275506
38.

[Sustained effect of nitroglycerin ointment on exercise tolerance in patients with effort angina (author's transl)].

Previtali M, Salerno JA, Falcone C, Lepore R, Chimienti M, Medici A, Angoli L, Bobba P.

G Ital Cardiol. 1980;10(5):584-91. Italian.

PMID:
6778754
39.

[Nitroglycerin ointment in spontaneous angina pectoris. Short-term observations].

Salerno JA, Previtali M, Medici A, Chimienti M, Ray M, De Servi RS, Querciolli MT, Lepore R, Bobba P.

Boll Soc Ital Cardiol. 1979;24(8):883-4. Italian. No abstract available.

PMID:
121797
40.

Clinical evaluation of dexamethasone 17-valerate in the topical therapy of eczema.

Dotti M, Lepore R, Franchi A, Fici F.

Panminerva Med. 1978 Jul-Sep;20(3):191-66. No abstract available.

PMID:
757286
41.

[Clinical trial of the use of a drug combination in gastroenterology].

Nizzo MC, Mavilio R, Lepore R.

Clin Ter. 1978 Mar 15;84(5):491-500. Italian. No abstract available.

PMID:
348384
42.

Loss of color from Jiffy tubes.

Going RE, Torosian G, Lepore RA.

J Am Dent Assoc. 1978 Jan;96(1):91-5.

PMID:
271168
43.

Effect of orange juice consumption on urinary pH.

Embil K, Litwiller DC, Lepore RA, Field FP, Torosian G.

Am J Hosp Pharm. 1976 Dec;33(12):1294-7.

PMID:
11688
44.

[Studies on the therapy of dyspeptic syndromes using a new pharmacologic combination].

Corsini P, Lepore R, Mordini M, Quaranta S.

Clin Ter. 1976 Aug 15;78(3):253-63. Italian. No abstract available.

PMID:
795596

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