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Items: 32

1.

Asparaginase-Associated Pancreatitis in Acute Lymphoblastic Leukemia: Results From the NOPHO ALL2008 Treatment of Patients 1-45 Years of Age.

Rank CU, Wolthers BO, Grell K, Albertsen BK, Frandsen TL, Overgaard UM, Toft N, Nielsen OJ, Wehner PS, Harila-Saari A, Heyman MM, Malmros J, Abrahamsson J, Norén-Nyström U, Tomaszewska-Toporska B, Lund B, Jarvis KB, Quist-Paulsen P, Vaitkevičienė GE, Griškevičius L, Taskinen M, Wartiovaara-Kautto U, Lepik K, Punab M, Jónsson ÓG, Schmiegelow K.

J Clin Oncol. 2020 Jan 10;38(2):145-154. doi: 10.1200/JCO.19.02208. Epub 2019 Nov 26.

PMID:
31770057
2.

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits.

Porcu E, Rüeger S, Lepik K; eQTLGen Consortium; BIOS Consortium, Santoni FA, Reymond A, Kutalik Z.

Nat Commun. 2019 Jul 24;10(1):3300. doi: 10.1038/s41467-019-10936-0.

3.

An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank.

James G, Reisberg S, Lepik K, Galwey N, Avillach P, Kolberg L, Mägi R, Esko T, Alexander M, Waterworth D, Loomis AK, Vilo J.

PLoS One. 2019 Apr 12;14(4):e0215026. doi: 10.1371/journal.pone.0215026. eCollection 2019.

4.

Pathological discrepancies in the diagnosis of thymic epithelial tumors: the Tallinn-Lyon experience.

Oselin K, Girard N, Lepik K, Adamson-Raieste A, Vanakesa T, Almre I, Leismann T, Chalabreysse L.

J Thorac Dis. 2019 Feb;11(2):456-464. doi: 10.21037/jtd.2018.12.123.

5.

Prevalence of Human Immunodeficiency Virus-1 Integrase Strand Transfer Inhibitor Resistance in British Columbia, Canada Between 2009 and 2016: A Longitudinal Analysis.

Kamelian K, Lepik KJ, Chau W, Yip B, Zhang WW, Lima VD, Robbins MA, Woods C, Olmstead A, Joy JB, Barrios R, Harrigan PR.

Open Forum Infect Dis. 2019 Feb 12;6(3):ofz060. doi: 10.1093/ofid/ofz060. eCollection 2019 Mar.

6.

Safe and Effective Delivery of Antitumor Drug Using Mesenchymal Stem Cells Impregnated with Submicron Carriers.

Timin AS, Peltek OO, Zyuzin MV, Muslimov AR, Karpov TE, Epifanovskaya OS, Shakirova AI, Zhukov MV, Tarakanchikova YV, Lepik KV, Sergeev VS, Sukhorukov GB, Afanasyev BV.

ACS Appl Mater Interfaces. 2019 Apr 10;11(14):13091-13104. doi: 10.1021/acsami.8b22685. Epub 2019 Mar 27.

PMID:
30883080
7.

Nivolumab for the treatment of relapsed and refractory classical Hodgkin lymphoma after ASCT and in ASCT-naïve patients.

Lepik KV, Mikhailova NB, Moiseev IS, Kondakova EV, Tsvetkova LA, Zalyalov YR, Borzenkova ES, Babenko EV, Baykov VV, Markova IV, Afanasyev BV.

Leuk Lymphoma. 2019 Sep;60(9):2316-2319. doi: 10.1080/10428194.2019.1573368. Epub 2019 Feb 4. No abstract available.

PMID:
30712423
8.

Treatment decisions in adolescents and young adults with gastric cancer in North Estonia Medical Centre from 2007-2016.

Lõhmus M, Lepik K, Kütt T, Seufferlein T, Oselin K.

Ann Oncol. 2018 Jun;29 Suppl 5:v3. doi: 10.1093/annonc/mdy151.007. Epub 2020 Jan 7. No abstract available.

9.

Adverse drug reactions to integrase strand transfer inhibitors.

Lepik KJ, Yip B, Ulloa AC, Wang L, Toy J, Akagi L, Lima VD, Guillemi S, Montaner JSG, Barrios R.

AIDS. 2018 Apr 24;32(7):903-912. doi: 10.1097/QAD.0000000000001781.

PMID:
29424784
10.

C-reactive protein upregulates the whole blood expression of CD59 - an integrative analysis.

Lepik K, Annilo T, Kukuškina V; eQTLGen Consortium, Kisand K, Kutalik Z, Peterson P, Peterson H.

PLoS Comput Biol. 2017 Sep 18;13(9):e1005766. doi: 10.1371/journal.pcbi.1005766. eCollection 2017 Sep.

11.

Efficient gene editing via non-viral delivery of CRISPR-Cas9 system using polymeric and hybrid microcarriers.

Timin AS, Muslimov AR, Lepik KV, Epifanovskaya OS, Shakirova AI, Mock U, Riecken K, Okilova MV, Sergeev VS, Afanasyev BV, Fehse B, Sukhorukov GB.

Nanomedicine. 2018 Jan;14(1):97-108. doi: 10.1016/j.nano.2017.09.001. Epub 2017 Sep 14.

PMID:
28917642
12.

A comparison study between electrospun polycaprolactone and piezoelectric poly(3-hydroxybutyrate-co-3-hydroxyvalerate) scaffolds for bone tissue engineering.

Gorodzha SN, Muslimov AR, Syromotina DS, Timin AS, Tcvetkov NY, Lepik KV, Petrova AV, Surmeneva MA, Gorin DA, Sukhorukov GB, Surmenev RA.

Colloids Surf B Biointerfaces. 2017 Dec 1;160:48-59. doi: 10.1016/j.colsurfb.2017.09.004. Epub 2017 Sep 5.

PMID:
28917149
13.

Emergent drug resistance with integrase strand transfer inhibitor-based regimens.

Lepik KJ, Harrigan PR, Yip B, Wang L, Robbins MA, Zhang WW, Toy J, Akagi L, Lima VD, Guillemi S, Montaner JSG, Barrios R.

AIDS. 2017 Jun 19;31(10):1425-1434. doi: 10.1097/QAD.0000000000001494.

PMID:
28375875
14.

Hybrid inorganic-organic capsules for efficient intracellular delivery of novel siRNAs against influenza A (H1N1) virus infection.

Timin AS, Muslimov AR, Petrova AV, Lepik KV, Okilova MV, Vasin AV, Afanasyev BV, Sukhorukov GB.

Sci Rep. 2017 Mar 7;7(1):102. doi: 10.1038/s41598-017-00200-0.

15.

Mesenchymal Stem Cell Magnetization: Magnetic Multilayer Microcapsule Uptake, Toxicity, Impact on Functional Properties, and Perspectives for Magnetic Delivery.

Lepik KV, Muslimov AR, Timin AS, Sergeev VS, Romanyuk DS, Moiseev IS, Popova EV, Radchenko IL, Vilesov AD, Galibin OV, Sukhorukov GB, Afanasyev BV.

Adv Healthc Mater. 2016 Dec;5(24):3182-3190. doi: 10.1002/adhm.201600843. Epub 2016 Nov 18.

PMID:
27860430
16.

Intracellular redox induced drug release in cancerous and mesenchymal stem cells.

Timin AS, Lepik KV, Muslimov AR, Gorin DA, Afanasyev BV, Sukhorukov GB.

Colloids Surf B Biointerfaces. 2016 Nov 1;147:450-458. doi: 10.1016/j.colsurfb.2016.08.034. Epub 2016 Aug 23.

PMID:
27573039
17.

Efficacy of Dasatinib in a CML Patient in Blast Crisis with F317L Mutation: A Case Report and Literature Review.

Morozova EV, Vlasova YY, Pryanishnikova MV, Lepik KV, Afanasyev BV.

Biomark Insights. 2015 Dec 8;10(Suppl 3):43-7. doi: 10.4137/BMI.S22438. eCollection 2015. Review.

18.

Post-marketing experience with nevirapine extended release (XR) tablets: effectiveness and tolerability in a population-based cohort in British Columbia, Canada.

Lepik KJ, Yip B, McGovern RA, Ding E, Nohpal A, Watson BE, Toy J, Akagi L, Harrigan PR, Moore DM, Hogg RS, Montaner JS, Barrios R.

Antivir Ther. 2015;20(7):721-30. doi: 10.3851/IMP2908. Epub 2014 Oct 27.

PMID:
25960569
19.

Declines in highly active antiretroviral therapy initiation at CD4 cell counts ≤ 200 cells/μL and the contribution of diagnosis of HIV at CD4 cell counts ≤ 200 cells/μL in British Columbia, Canada.

Lourenço L, Samji H, Nohpal A, Chau W, Colley G, Lepik K, Barrios R, Lima V, Hogg RS, Montaner J, Kesselring S, Moore DM.

HIV Med. 2015 Jul;16(6):337-45. doi: 10.1111/hiv.12212. Epub 2015 Feb 27.

20.

Vets, denialists and rememberers: social typologies of patient adherence and non-adherence to HAART from the perspective of HIV care providers.

Orchard T, Salters K, Palmer A, Michelow W, Lepik KJ, Hogg R.

AIDS Care. 2015;27(6):758-61. doi: 10.1080/09540121.2015.1005003. Epub 2015 Jan 30.

PMID:
25635938
21.

Anterior knee pain following total knee replacement correlates with the OARSI score of the cartilage of the patella.

Metsna V, Vorobjov S, Lepik K, Märtson A.

Acta Orthop. 2014 Aug;85(4):427-32. doi: 10.3109/17453674.2014.931198. Epub 2014 Jun 23.

22.

Low prevalence of IgA anti-transglutaminase 1, 2, and 3 autoantibodies in children with atopic dermatitis.

Ress K, Teesalu K, Annus T, Putnik U, Lepik K, Luts K, Uibo O, Uibo R.

BMC Res Notes. 2014 May 22;7:310. doi: 10.1186/1756-0500-7-310.

23.

Antinuclear antibodies in atopic dermatitis: a cross-sectional study on 346 children.

Ress K, Metsküla K, Annus T, Putnik U, Lepik K, Luts K, Uibo O, Uibo R.

Int J Dermatol. 2015 Jan;54(1):24-8. doi: 10.1111/ijd.12535. Epub 2014 Apr 16.

PMID:
24738492
24.

Cohort Profile: HAART Observational Medical Evaluation and Research (HOMER) cohort.

Patterson S, Cescon A, Samji H, Cui Z, Yip B, Lepik KJ, Moore D, Lima VD, Nosyk B, Harrigan PR, Montaner JS, Shannon K, Wood E, Hogg RS.

Int J Epidemiol. 2015 Feb;44(1):58-67. doi: 10.1093/ije/dyu046. Epub 2014 Mar 17.

25.

Trends in plasma HIV-RNA suppression and antiretroviral resistance in British Columbia, 1997-2010.

Cescon A, Kanters S, Brumme CJ, Lepik KJ, Forrest JI, Hull M, Samji H, Nosyk B, Harrigan PR, Hogg RS, Montaner JS.

J Acquir Immune Defic Syndr. 2014 Jan 1;65(1):107-14. doi: 10.1097/QAI.0b013e3182a8efc3.

26.

Medication errors associated with the use of ethanol and fomepizole as antidotes for methanol and ethylene glycol poisoning.

Lepik KJ, Sobolev BG, Levy AR, Purssell RA, Dewitt CR, Erhardt GD, Baker JL, Kennedy JR, Daws DE.

Clin Toxicol (Phila). 2011 Jun;49(5):391-401. doi: 10.3109/15563650.2011.580754.

PMID:
21740138
27.

Regional and temporal changes in HIV-related mortality in British Columbia, 1987-2006.

Lima VD, Lepik KJ, Zhang W, Muldoon KA, Hogg RS, Montaner JS.

Can J Public Health. 2010 Sep-Oct;101(5):415-9.

28.

Adverse drug events associated with the antidotes for methanol and ethylene glycol poisoning: a comparison of ethanol and fomepizole.

Lepik KJ, Levy AR, Sobolev BG, Purssell RA, DeWitt CR, Erhardt GD, Kennedy JR, Daws DE, Brignall JL.

Ann Emerg Med. 2009 Apr;53(4):439-450.e10. doi: 10.1016/j.annemergmed.2008.05.008. Epub 2008 Jul 18.

PMID:
18639955
29.

Bradycardia and hypotension associated with fomepizole infusion during hemodialysis.

Lepik KJ, Brubacher JR, DeWitt CR, Lam GS, Lawson EJ, Erhardt GD, Purssell RA, Kennedy JR, Brignall JL.

Clin Toxicol (Phila). 2008 Jul;46(6):570-3. doi: 10.1080/15563650701725128.

PMID:
18584373
30.

An evaluation of the osmole gap as a screening test for toxic alcohol poisoning.

Lynd LD, Richardson KJ, Purssell RA, Abu-Laban RB, Brubacher JR, Lepik KJ, Sivilotti ML.

BMC Emerg Med. 2008 Apr 28;8:5. doi: 10.1186/1471-227X-8-5.

31.

Adequacy of antidote stocking in British Columbia hospitals: the 2005 Antidote Stocking Study.

Wiens MO, Zed PJ, Lepik KJ, Abu-Laban RB, Brubacher JR, Gorman SK, Kent DA, Purssell RA.

CJEM. 2006 Nov;8(6):409-16.

PMID:
17209490
32.

Brain-stimulation reward thresholds raised by an antisense oligonucleotide for the M5 muscarinic receptor infused near dopamine cells.

Yeomans JS, Takeuchi J, Baptista M, Flynn DD, Lepik K, Nobrega J, Fulton J, Ralph MR.

J Neurosci. 2000 Dec 1;20(23):8861-7.

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