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Items: 1 to 50 of 131

1.

Determinants of intramyocellular lipid accumulation in early childhood.

Michael N, Gupta V, Sadananthan SA, Sampathkumar A, Chen L, Pan H, Tint MT, Lee KJ, Loy SL, Aris IM, Shek LP, Yap FKP, Godfrey KM, Leow MK, Lee YS, Kramer MS, Henry CJ, Fortier MV, Seng Chong Y, Gluckman PD, Karnani N, Velan SS.

Int J Obes (Lond). 2019 Aug 28. doi: 10.1038/s41366-019-0435-8. [Epub ahead of print]

PMID:
31462692
2.

Brown Adipose Tissue: Multimodality Evaluation by PET, MRI, Infrared Thermography, and Whole-Body Calorimetry (TACTICAL-II).

Sun L, Verma S, Michael N, Chan SP, Yan J, Sadananthan SA, Camps SG, Goh HJ, Govindharajulu P, Totman J, Townsend D, Goh JP, Sun L, Boehm BO, Lim SC, Sze SK, Henry CJ, Hu HH, Velan SS, Leow MK.

Obesity (Silver Spring). 2019 Sep;27(9):1434-1442. doi: 10.1002/oby.22560. Epub 2019 Jul 13.

PMID:
31301122
3.

Hyperthyroidism in the personalized medicine era: the rise of mathematical optimization.

Meng F, Li E, Yen PM, Leow MKS.

J R Soc Interface. 2019 Jun 28;16(155):20190083. doi: 10.1098/rsif.2019.0083. Epub 2019 Jun 26.

4.

Depletion interaction forces contribute to erythrocyte-endothelial adhesion in diabetes.

Kaliyaperumal R, Deng X, Meiselman HJ, Song H, Dalan R, Leow MK, Neu B.

Biochem Biophys Res Commun. 2019 Aug 13;516(1):144-148. doi: 10.1016/j.bbrc.2019.06.018. Epub 2019 Jun 11.

PMID:
31200959
5.

Postprandial glucose, insulin and incretin responses differ by test meal macronutrient ingestion sequence (PATTERN study).

Sun L, Goh HJ, Govindharajulu P, Leow MK, Henry CJ.

Clin Nutr. 2019 Apr 27. pii: S0261-5614(19)30154-2. doi: 10.1016/j.clnu.2019.04.001. [Epub ahead of print]

PMID:
31053510
6.

Dose-Dependent Effects of Exercise and Diet on Insulin Sensitivity and Secretion.

Ding C, Chooi YUC, Chan Z, Lo J, Choo J, Ding BTK, Leow MK, Magkos F.

Med Sci Sports Exerc. 2019 Oct;51(10):2109-2116. doi: 10.1249/MSS.0000000000002020.

PMID:
31033904
7.

Body Composition and Acquired Functional Impairment in Survivors of Pediatric Critical Illness.

Ong C, Lee JH, Senna S, Chia AZH, Wong JJM, Fortier MV, Leow MKS, Puthucheary ZA.

Crit Care Med. 2019 Jun;47(6):e445-e453. doi: 10.1097/CCM.0000000000003720.

PMID:
30958426
8.

Design of an online-tuned model based compound controller for a fully automated artificial pancreas.

Bhattacharjee A, Easwaran A, Leow MK, Cho N.

Med Biol Eng Comput. 2019 Jul;57(7):1437-1449. doi: 10.1007/s11517-019-01972-5. Epub 2019 Mar 20.

PMID:
30895514
9.

Associations of physical activity levels and screen time with oral glucose tolerance test profiles in Singaporean women of reproductive age actively trying to conceive: the S-PRESTO study.

Bernard JY, Ng S, Natarajan P, Loy SL, Aris IM, Tint MT, Chong YS, Shek L, Chan J, Godfrey KM, Khoo CM, Leow MK, Müller-Riemenschneider F, Chan SY.

Diabet Med. 2019 Jul;36(7):888-897. doi: 10.1111/dme.13948. Epub 2019 Apr 7.

PMID:
30888073
10.

Ectopic fat and aerobic fitness are key determinants of glucose homeostasis in nonobese Asians.

Chan Z, Ding C, Chooi YC, Choo J, Sadananthan SA, Sasikala S, Chang A, Michael N, Velan SS, Leow MK, Magkos F.

Eur J Clin Invest. 2019 May;49(5):e13079. doi: 10.1111/eci.13079. Epub 2019 Feb 25.

PMID:
30734926
11.

Association Between Early Life Weight Gain and Abdominal Fat Partitioning at 4.5 Years is Sex, Ethnicity, and Age Dependent.

Sadananthan SA, Tint MT, Michael N, Aris IM, Loy SL, Lee KJ, Shek LP, Yap FKP, Tan KH, Godfrey KM, Leow MK, Lee YS, Kramer MS, Gluckman PD, Chong YS, Karnani N, Henry CJ, Fortier MV, Velan SS.

Obesity (Silver Spring). 2019 Mar;27(3):470-478. doi: 10.1002/oby.22408. Epub 2019 Feb 1.

12.

Lipoprotein Subclass Profile after Progressive Energy Deficits Induced by Calorie Restriction or Exercise.

Chooi YC, Ding C, Chan Z, Lo J, Choo J, Ding BTK, Leow MK, Magkos F.

Nutrients. 2018 Nov 21;10(11). pii: E1814. doi: 10.3390/nu10111814.

13.

Oxytocin in metabolic homeostasis: implications for obesity and diabetes management.

Ding C, Leow MK, Magkos F.

Obes Rev. 2019 Jan;20(1):22-40. doi: 10.1111/obr.12757. Epub 2018 Sep 25. Review.

PMID:
30253045
14.

Sex Differences in Glucose and Fatty Acid Metabolism in Asians Who Are Nonobese.

Chan Z, Chooi YC, Ding C, Choo J, Sadananthan SA, Michael N, Velan SS, Leow MK, Magkos F.

J Clin Endocrinol Metab. 2019 Jan 1;104(1):127-136. doi: 10.1210/jc.2018-01421.

PMID:
30252100
15.

Ethnicity-Specific Skeletal Muscle Transcriptional Signatures and Their Relevance to Insulin Resistance in Singapore.

Tan ALM, Langley SR, Tan CF, Chai JF, Khoo CM, Leow MK, Khoo EYH, Moreno-Moral A, Pravenec M, Rotival M, Sadananthan SA, Velan SS, Venkataraman K, Chong YS, Lee YS, Sim X, Stunkel W, Liu MH, Tai ES, Petretto E.

J Clin Endocrinol Metab. 2019 Feb 1;104(2):465-486. doi: 10.1210/jc.2018-00309.

PMID:
30137523
16.

Visceral adipose tissue tracks more closely with metabolic dysfunction than intrahepatic triglyceride in lean Asians without diabetes.

Ding C, Chan Z, Chooi YC, Choo J, Sadananthan SA, Michael N, Velan SS, Leow MKS, Magkos F.

J Appl Physiol (1985). 2018 Sep 1;125(3):909-915. doi: 10.1152/japplphysiol.00250.2018. Epub 2018 May 10.

17.

Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD.

Bruinstroop E, Dalan R, Cao Y, Bee YM, Chandran K, Cho LW, Soh SB, Teo EK, Toh SA, Leow MKS, Sinha RA, Sadananthan SA, Michael N, Stapleton HM, Leung C, Angus PW, Patel SK, Burrell LM, Lim SC, Sum CF, Velan SS, Yen PM.

J Clin Endocrinol Metab. 2018 Jul 1;103(7):2698-2706. doi: 10.1210/jc.2018-00475.

PMID:
29718334
18.

Erratum: Author Correction: Angiotensin type 2 receptor activation promotes browning of white adipose tissue and brown adipogenesis.

Than A, Xu S, Li R, Leow MK, Sun L, Chen P.

Signal Transduct Target Ther. 2018 Apr 19;3:10. doi: 10.1038/s41392-018-0014-9. eCollection 2018.

19.

De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis.

Ding C, Lim YC, Chia SY, Walet ACE, Xu S, Lo KA, Zhao Y, Zhu D, Shan Z, Chen Q, Leow MK, Xu D, Sun L.

Nat Commun. 2018 Apr 6;9(1):1329. doi: 10.1038/s41467-018-03754-3.

20.

Adipocyte Long-Noncoding RNA Transcriptome Analysis of Obese Mice Identified Lnc-Leptin, Which Regulates Leptin.

Lo KA, Huang S, Walet ACE, Zhang ZC, Leow MK, Liu M, Sun L.

Diabetes. 2018 Jun;67(6):1045-1056. doi: 10.2337/db17-0526. Epub 2018 Mar 8.

21.

Central diabetes insipidus unmasked by corticosteroid therapy for cerebral metastases: beware the case with pituitary involvement and hypopituitarism.

Chin HX, Quek TP, Leow MK.

J R Coll Physicians Edinb. 2017 Sep;47(3):247-249. doi: 10.4997/JRCPE.2017.307.

PMID:
29465100
22.

Capsinoids activate brown adipose tissue (BAT) with increased energy expenditure associated with subthreshold 18-fluorine fluorodeoxyglucose uptake in BAT-positive humans confirmed by positron emission tomography scan.

Sun L, Camps SG, Goh HJ, Govindharajulu P, Schaefferkoetter JD, Townsend DW, Verma SK, Velan SS, Sun L, Sze SK, Lim SC, Boehm BO, Henry CJ, Leow MK.

Am J Clin Nutr. 2018 Jan 1;107(1):62-70. doi: 10.1093/ajcn/nqx025.

PMID:
29381803
23.

Low subjective socioeconomic status stimulates orexigenic hormone ghrelin - A randomised trial.

Sim AY, Lim EX, Leow MK, Cheon BK.

Psychoneuroendocrinology. 2018 Mar;89:103-112. doi: 10.1016/j.psyneuen.2018.01.006. Epub 2018 Jan 12.

PMID:
29358119
24.

Angiotensin type 2 receptor activation promotes browning of white adipose tissue and brown adipogenesis.

Than A, Xu S, Li R, Leow MK, Sun L, Chen P.

Signal Transduct Target Ther. 2017 Jun 23;2:17022. doi: 10.1038/sigtrans.2017.22. eCollection 2017. Erratum in: Signal Transduct Target Ther. 2018 Apr 19;3:10.

25.

Polyphenol-rich curry made with mixed spices and vegetables benefits glucose homeostasis in Chinese males (Polyspice Study): a dose-response randomized controlled crossover trial.

Haldar S, Chia SC, Lee SH, Lim J, Leow MK, Chan ECY, Henry CJ.

Eur J Nutr. 2019 Feb;58(1):301-313. doi: 10.1007/s00394-017-1594-9. Epub 2017 Dec 13.

PMID:
29236165
26.

Giant phaeochromocytoma presenting with an acute stroke: reappraising phaeochromocytoma surveillance for the neurofibromatosis type 1 phakomatosis.

Lee Y, Tan LYR, Ho YH, Leow MKS.

BMJ Case Rep. 2017 Nov 3;2017. pii: bcr-2017-222553. doi: 10.1136/bcr-2017-222553.

PMID:
29102976
27.

Skeletal Muscle Ultrasonography in Nutrition and Functional Outcome Assessment of Critically Ill Children: Experience and Insights From Pediatric Disease and Adult Critical Care Studies [Formula: see text].

Ong C, Lee JH, Leow MKS, Puthucheary ZA.

JPEN J Parenter Enteral Nutr. 2017 Sep;41(7):1091-1099. doi: 10.1177/0148607116683143. Epub 2016 Dec 1. Review.

PMID:
29049016
28.
29.

RNA Binding Protein Ybx2 Regulates RNA Stability During Cold-Induced Brown Fat Activation.

Xu D, Xu S, Kyaw AMM, Lim YC, Chia SY, Chee Siang DT, Alvarez-Dominguez JR, Chen P, Leow MK, Sun L.

Diabetes. 2017 Dec;66(12):2987-3000. doi: 10.2337/db17-0655. Epub 2017 Sep 29.

30.

Characterization of the Asian Phenotype - An Emerging Paradigm with Clinicopathological and Human Research Implications.

Leow MK.

Int J Med Sci. 2017 Jun 15;14(7):639-647. doi: 10.7150/ijms.18880. eCollection 2017. Review.

31.

Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model.

Ohba K, Sinha RA, Singh BK, Iannucci LF, Zhou J, Kovalik JP, Liao XH, Refetoff S, Sng JCG, Leow MK, Yen PM.

Thyroid. 2017 Jun;27(6):852-860. doi: 10.1089/thy.2016.0456. Epub 2017 May 24.

32.

A synopsis of brown adipose tissue imaging modalities for clinical research.

Sun L, Yan J, Sun L, Velan SS, Leow MKS.

Diabetes Metab. 2017 Oct;43(5):401-410. doi: 10.1016/j.diabet.2017.03.008. Epub 2017 Apr 25. Review.

PMID:
28455113
33.

Personalized glucose-insulin model based on signal analysis.

Goede SL, de Galan BE, Leow MKS.

J Theor Biol. 2017 Apr 21;419:333-342. doi: 10.1016/j.jtbi.2016.12.018. Epub 2016 Dec 28.

PMID:
28039012
35.
36.

Fruit Consumption and Cardiovascular Disease in China.

Leow MK.

N Engl J Med. 2016 Aug 4;375(5):487-8. doi: 10.1056/NEJMc1606624. No abstract available.

PMID:
27518674
37.

Demethylation and re-methylation dynamics in transgenerational epigenetic inheritance.

Leow MK.

J Steroid Biochem Mol Biol. 2016 Oct;163:212. doi: 10.1016/j.jsbmb.2016.07.011. Epub 2016 Aug 2. No abstract available.

PMID:
27496588
38.

A new method of infrared thermography for quantification of brown adipose tissue activation in healthy adults (TACTICAL): a randomized trial.

Ang QY, Goh HJ, Cao Y, Li Y, Chan SP, Swain JL, Henry CJ, Leow MK.

J Physiol Sci. 2017 May;67(3):395-406. doi: 10.1007/s12576-016-0472-1. Epub 2016 Jul 21.

39.

A Review of the Phenomenon of Hysteresis in the Hypothalamus-Pituitary-Thyroid Axis.

Leow MK.

Front Endocrinol (Lausanne). 2016 Jun 14;7:64. doi: 10.3389/fendo.2016.00064. eCollection 2016. Review.

40.

The haptoglobin 2-2 genotype is associated with inflammation and carotid artery intima-media thickness.

Dalan R, Liew H, Goh LL, Gao X, Chew DE, Boehm BO, Leow MK.

Diab Vasc Dis Res. 2016 Sep;13(5):373-6. doi: 10.1177/1479164116645247. Epub 2016 May 16.

41.

Combination of soya protein and polydextrose reduces energy intake and glycaemic response via modulation of gastric emptying rate, ghrelin and glucagon-like peptide-1 in Chinese.

Soong YY, Lim WX, Leow MK, Siow PC, Teh AL, Henry CJ.

Br J Nutr. 2016 Jun;115(12):2130-7. doi: 10.1017/S0007114516001689.

PMID:
27185412
42.

Letter to the Editor: The Ultimate Proof of the Log-linear Nature of TSH-Free T4 Relationship by Intraindividual Analysis of a Large Population.

Goede SL, Leow MK.

J Clin Endocrinol Metab. 2016 May;101(5):L57-8. doi: 10.1210/jc.2016-1439. No abstract available.

PMID:
27163472
43.

Functional Outcomes and Physical Impairments in Pediatric Critical Care Survivors: A Scoping Review.

Ong C, Lee JH, Leow MK, Puthucheary ZA.

Pediatr Crit Care Med. 2016 May;17(5):e247-59. doi: 10.1097/PCC.0000000000000706. Review.

PMID:
27030932
45.

Psychometric analysis of an eating behaviour questionnaire for an overweight and obese Chinese population in Singapore.

Chong MF, Ayob MN, Chong KJ, Tai ES, Khoo CM, Leow MK, Lee YS, Tham KW, Venkataraman K, Meaney MJ, Wee HL, Khoo EY.

Appetite. 2016 Jun 1;101:119-24. doi: 10.1016/j.appet.2016.03.005. Epub 2016 Mar 2.

PMID:
26946279
46.

The transcription factor SOX6 contributes to the developmental origins of obesity by promoting adipogenesis.

Leow SC, Poschmann J, Too PG, Yin J, Joseph R, McFarlane C, Dogra S, Shabbir A, Ingham PW, Prabhakar S, Leow MK, Lee YS, Ng KL, Chong YS, Gluckman PD, Stünkel W.

Development. 2016 Mar 15;143(6):950-61. doi: 10.1242/dev.131573. Epub 2016 Feb 18.

47.

Desensitization and Incomplete Recovery of Hepatic Target Genes After Chronic Thyroid Hormone Treatment and Withdrawal in Male Adult Mice.

Ohba K, Leow MK, Singh BK, Sinha RA, Lesmana R, Liao XH, Ghosh S, Refetoff S, Sng JC, Yen PM.

Endocrinology. 2016 Apr;157(4):1660-72. doi: 10.1210/en.2015-1848. Epub 2016 Feb 11.

48.

A randomised controlled trial evaluating the impact of targeted vitamin D supplementation on endothelial function in type 2 diabetes mellitus: The DIMENSION trial.

Dalan R, Liew H, Assam PN, Chan ES, Siddiqui FJ, Tan AW, Chew DE, Boehm BO, Leow MK.

Diab Vasc Dis Res. 2016 May;13(3):192-200. doi: 10.1177/1479164115621667. Epub 2016 Jan 27.

49.

FTO Obesity Variant and Adipocyte Browning in Humans.

Leow MK.

N Engl J Med. 2016 Jan 14;374(2):191-2. doi: 10.1056/NEJMc1513316. No abstract available.

PMID:
26760099
50.

Segmentation and characterization of interscapular brown adipose tissue in rats by multi-parametric magnetic resonance imaging.

Bhanu Prakash KN, Verma SK, Yaligar J, Goggi J, Gopalan V, Lee SS, Tian X, Sugii S, Leow MK, Bhakoo K, Velan SS.

MAGMA. 2016 Apr;29(2):277-86. doi: 10.1007/s10334-015-0514-3. Epub 2016 Jan 8.

PMID:
26747282

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