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Items: 1 to 50 of 135

1.

Application of Externally Applied Lower Punch Vibration and its Effects on Tablet Manufacturing.

Kalies A, Özcoban H, Leopold CS.

Pharm Res. 2019 Oct 28;36(12):173. doi: 10.1007/s11095-019-2711-7.

PMID:
31659476
2.

Combination of a hot-melt subcoating and an enteric coating for moisture protection of hygroscopic Sennae fructus tablets.

Zier KI, Schultze W, Leopold CS.

Pharm Dev Technol. 2019 Dec;24(10):1210-1217. doi: 10.1080/10837450.2019.1648509. Epub 2019 Aug 23.

PMID:
31354006
3.

Out-of-Pocket Cancer Care Costs and Value Frameworks: A Case Study in a Community Oncology Practice with a Financial Navigator Program.

Leopold C, Araujo-Lane C, Rosenberg C, Gilkey M, Wagner AK.

Pharmacoecon Open. 2019 Jul 19. doi: 10.1007/s41669-019-0170-z. [Epub ahead of print] No abstract available.

4.

Facilitating adaptation to climate change while restoring a montane plant community.

Leopold CR, Hess SC.

PLoS One. 2019 Jun 20;14(6):e0218516. doi: 10.1371/journal.pone.0218516. eCollection 2019.

5.

Influence of the feed frame design on the powder behavior and the residence time distribution.

Dülle M, Özcoban H, Leopold CS.

Int J Pharm. 2019 Jun 30;565:523-532. doi: 10.1016/j.ijpharm.2019.05.026. Epub 2019 May 15.

PMID:
31102806
6.

Performance Characteristics of a Novel Vibration Technique for the Densification of a Powder Bed within a Die of a Rotary Tablet Press - a Proof of Concept.

Kalies A, Özcoban H, Leopold CS.

AAPS PharmSciTech. 2019 Mar 20;20(4):148. doi: 10.1208/s12249-019-1351-x.

PMID:
30895389
7.

Intestine-Specific Overexpression of Carboxylesterase 2c Protects Mice From Diet-Induced Liver Steatosis and Obesity.

Maresch LK, Benedikt P, Feiler U, Eder S, Zierler KA, Taschler U, Kolleritsch S, Eichmann TO, Schoiswohl G, Leopold C, Wieser BI, Lackner C, Rülicke T, van Klinken J, Kratky D, Moustafa T, Hoefler G, Haemmerle G.

Hepatol Commun. 2018 Dec 17;3(2):227-245. doi: 10.1002/hep4.1292. eCollection 2019 Feb.

8.

Comparison of two paddle wheel geometries within the filling chamber of a rotary tablet press feed frame with regard to the distribution behavior of a model powder and the influence on the resulting tablet mass.

Dühlmeyer KP, Özcoban H, Leopold CS.

Drug Dev Ind Pharm. 2019 Aug;45(8):1233-1241. doi: 10.1080/03639045.2019.1576725. Epub 2019 May 27.

PMID:
30724111
9.

In situ co-amorphisation in coated tablets - The combination of carvedilol with aspartic acid during immersion in an acidic medium.

Petry I, Löbmann K, Grohganz H, Rades T, Leopold CS.

Int J Pharm. 2019 Mar 10;558:357-366. doi: 10.1016/j.ijpharm.2018.12.091. Epub 2019 Jan 12.

PMID:
30641182
10.

Hepatocyte-specific lysosomal acid lipase deficiency protects mice from diet-induced obesity but promotes hepatic inflammation.

Leopold C, Duta-Mare M, Sachdev V, Goeritzer M, Maresch LK, Kolb D, Reicher H, Wagner B, Stojakovic T, Ruelicke T, Haemmerle G, Hoefler G, Sattler W, Kratky D.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Apr;1864(4):500-511. doi: 10.1016/j.bbalip.2019.01.007. Epub 2019 Jan 9.

11.

Comparison of Analytical Approaches Predicting the Compressive Strength of Fibre Reinforced Polymers.

Leopold C, Harder S, Philipkowski T, Liebig WV, Fiedler B.

Materials (Basel). 2018 Dec 11;11(12). pii: E2517. doi: 10.3390/ma11122517.

12.

The effect of different feed frame components on the powder behavior and the residence time distribution with regard to the continuous manufacturing of tablets.

Dülle M, Özcoban H, Leopold CS.

Int J Pharm. 2019 Jan 30;555:220-227. doi: 10.1016/j.ijpharm.2018.11.017. Epub 2018 Nov 9.

PMID:
30419296
13.

In situ co-amorphisation of arginine with indomethacin or furosemide during immersion in an acidic medium - A proof of concept study.

Petry I, Löbmann K, Grohganz H, Rades T, Leopold CS.

Eur J Pharm Biopharm. 2018 Dec;133:151-160. doi: 10.1016/j.ejpb.2018.10.011. Epub 2018 Oct 16.

PMID:
30339888
14.

Analysis of the powder behavior and the residence time distribution within a production scale rotary tablet press.

Dülle M, Özcoban H, Leopold CS.

Eur J Pharm Sci. 2018 Dec 1;125:205-214. doi: 10.1016/j.ejps.2018.10.008. Epub 2018 Oct 9.

PMID:
30312745
15.

An analysis of expenditures on primary care prescription drugs in the United States versus ten comparable countries.

Morgan SG, Good CB, Leopold C, Kaltenboeck A, Bach PB, Wagner A.

Health Policy. 2018 Sep;122(9):1012-1017. doi: 10.1016/j.healthpol.2018.07.005. Epub 2018 Jul 21.

PMID:
30041827
16.

A novel method for determination of the filling level in the feed frame of a rotary tablet press.

Dühlmeyer KP, Özcoban H, Leopold CS.

Drug Dev Ind Pharm. 2018 Nov;44(11):1744-1751. doi: 10.1080/03639045.2018.1492609. Epub 2018 Aug 22.

PMID:
29961339
17.

Factors influencing the properties and the stability of spray-dried Sennae fructus extracts.

Zier KI, Schultze W, Leopold CS.

Drug Dev Ind Pharm. 2018 Oct;44(10):1659-1667. doi: 10.1080/03639045.2018.1483397. Epub 2018 Aug 8.

PMID:
29954227
18.

Total and out-of-pocket expenditures among women with metastatic breast cancer in low-deductible versus high-deductible health plans.

Leopold C, Wagner AK, Zhang F, Lu CY, Earle CC, Nekhlyudov L, Ross-Degnan D, Wharam JF.

Breast Cancer Res Treat. 2018 Sep;171(2):449-459. doi: 10.1007/s10549-018-4819-6. Epub 2018 Jun 1.

19.

Defining Value of Cancer Therapeutics-A Health System Perspective.

Leopold C, Peppercorn JM, Zafar SY, Wagner AK.

J Natl Cancer Inst. 2018 Jul 1;110(7):699-703. doi: 10.1093/jnci/djy079. Review.

PMID:
29788313
20.

Risk Factors for Failure of Systemic-to-Pulmonary Artery Shunts in Biventricular Circulation.

Vitanova K, Leopold C, Pabst von Ohain J, Wolf C, Beran E, Lange R, Cleuziou J.

Pediatr Cardiol. 2018 Oct;39(7):1323-1329. doi: 10.1007/s00246-018-1898-4. Epub 2018 May 14.

PMID:
29756161
21.

Undesired co-amorphisation of indomethacin and arginine during combined storage at high humidity conditions.

Petry I, Löbmann K, Grohganz H, Rades T, Leopold CS.

Int J Pharm. 2018 Jun 10;544(1):172-180. doi: 10.1016/j.ijpharm.2018.04.026. Epub 2018 Apr 15.

PMID:
29669257
22.

Myristic acid induces proteomic and secretomic changes associated with steatosis, cytoskeleton remodeling, endoplasmic reticulum stress, protein turnover and exosome release in HepG2 cells.

Speziali G, Liesinger L, Gindlhuber J, Leopold C, Pucher B, Brandi J, Castagna A, Tomin T, Krenn P, Thallinger GG, Olivieri O, Martinelli N, Kratky D, Schittmayer M, Birner-Gruenberger R, Cecconi D.

J Proteomics. 2018 Jun 15;181:118-130. doi: 10.1016/j.jprot.2018.04.008. Epub 2018 Apr 12.

PMID:
29654920
23.

A comparative study on the sticking tendency of ibuprofen and ibuprofen sodium dihydrate to differently coated tablet punches.

Al-Karawi C, Leopold CS.

Eur J Pharm Biopharm. 2018 Jul;128:107-118. doi: 10.1016/j.ejpb.2018.04.004. Epub 2018 Apr 7.

PMID:
29635014
24.

Investigation of the tableting behavior of Ibuprofen DC 85 W.

Al-Karawi C, Cech T, Bang F, Leopold CS.

Drug Dev Ind Pharm. 2018 Aug;44(8):1262-1272. doi: 10.1080/03639045.2018.1442846. Epub 2018 Mar 22.

PMID:
29499616
25.

Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis.

Duta-Mare M, Sachdev V, Leopold C, Kolb D, Vujic N, Korbelius M, Hofer DC, Xia W, Huber K, Auer M, Gottschalk B, Magnes C, Graier WF, Prokesch A, Radovic B, Bogner-Strauss JG, Kratky D.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Apr;1863(4):467-478. doi: 10.1016/j.bbalip.2018.01.011. Epub 2018 Jan 31.

26.

Reasons for Failure of Systemic-to-Pulmonary Artery Shunts in Neonates.

Vitanova K, Leopold C, von Ohain JP, Wolf C, Beran E, Lange R, Cleuziou J.

Thorac Cardiovasc Surg. 2019 Jan;67(1):2-7. doi: 10.1055/s-0037-1621706. Epub 2018 Jan 19.

PMID:
29351695
27.

A non-destructive method for quality control of the pellet distribution within a MUPS tablet by terahertz pulsed imaging.

Novikova A, Markl D, Zeitler JA, Rades T, Leopold CS.

Eur J Pharm Sci. 2018 Jan 1;111:549-555. doi: 10.1016/j.ejps.2017.10.029. Epub 2017 Oct 19.

28.

Compression Fracture of CFRP Laminates Containing Stress Intensifications.

Leopold C, Schütt M, Liebig WV, Philipkowski T, Kürten J, Schulte K, Fiedler B.

Materials (Basel). 2017 Sep 5;10(9). pii: E1039. doi: 10.3390/ma10091039.

29.

UV imaging of multiple unit pellet system (MUPS) tablets: A case study of acetylsalicylic acid stability.

Novikova A, Carstensen JM, Rades T, Leopold CS.

Eur J Pharm Biopharm. 2017 Oct;119:447-453. doi: 10.1016/j.ejpb.2017.08.002. Epub 2017 Aug 2.

PMID:
28780276
30.

A novel technique for the visualization of tablet punch surfaces: Characterization of surface modification, wear and sticking.

Al-Karawi C, Kaiser T, Leopold CS.

Int J Pharm. 2017 Sep 15;530(1-2):440-454. doi: 10.1016/j.ijpharm.2017.08.006. Epub 2017 Aug 3.

PMID:
28779987
31.

Influence of carbon nanoparticle modification on the mechanical and electrical properties of epoxy in small volumes.

Leopold C, Augustin T, Schwebler T, Lehmann J, Liebig WV, Fiedler B.

J Colloid Interface Sci. 2017 Nov 15;506:620-632. doi: 10.1016/j.jcis.2017.07.085. Epub 2017 Jul 25.

32.

Drivers of expenditure on primary care prescription drugs in 10 high-income countries with universal health coverage.

Morgan SG, Leopold C, Wagner AK.

CMAJ. 2017 Jun 12;189(23):E794-E799. doi: 10.1503/cmaj.161481.

33.

Solid state properties and drug release behavior of co-amorphous indomethacin-arginine tablets coated with Kollicoat® Protect.

Petry I, Löbmann K, Grohganz H, Rades T, Leopold CS.

Eur J Pharm Biopharm. 2017 Oct;119:150-160. doi: 10.1016/j.ejpb.2017.06.007. Epub 2017 Jun 8.

PMID:
28602869
34.

The Impact of the Affordable Care Act on Cancer Survivorship.

Leopold C, Park ER, Nekhlyudov L.

Cancer J. 2017 May/Jun;23(3):181-189. doi: 10.1097/PPO.0000000000000263.

PMID:
28537964
35.

A rapidly changing global medicines environment: How adaptable are funding decision-making systems?

Leopold C, Morgan SG, Wagner AK.

Health Policy. 2017 Jun;121(6):637-643. doi: 10.1016/j.healthpol.2017.04.002. Epub 2017 Apr 10.

PMID:
28449884
36.

Lysosomal lipid hydrolysis provides substrates for lipid mediator synthesis in murine macrophages.

Schlager S, Vujic N, Korbelius M, Duta-Mare M, Dorow J, Leopold C, Rainer S, Wegscheider M, Reicher H, Ceglarek U, Sattler W, Radovic B, Kratky D.

Oncotarget. 2017 Jun 20;8(25):40037-40051. doi: 10.18632/oncotarget.16673.

37.

Improvement of the physicochemical properties of Co-amorphous naproxen-indomethacin by naproxen-sodium.

Beyer A, Grohganz H, Löbmann K, Rades T, Leopold CS.

Int J Pharm. 2017 Jun 30;526(1-2):88-94. doi: 10.1016/j.ijpharm.2017.04.011. Epub 2017 Apr 6.

PMID:
28392278
38.

Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE-/- mice.

Vujic N, Korbelius M, Leopold C, Duta-Mare M, Rainer S, Schlager S, Goeritzer M, Kolb D, Eichmann TO, Diwoky C, Zimmer A, Zimmermann R, Lass A, Radovic B, Kratky D.

Oncotarget. 2017 May 16;8(20):33122-33136. doi: 10.18632/oncotarget.16529.

39.

Multispectral UV Imaging for Determination of the Tablet Coating Thickness.

Novikova A, Carstensen JM, Zeitler JA, Rades T, Leopold CS.

J Pharm Sci. 2017 Jun;106(6):1560-1569. doi: 10.1016/j.xphs.2017.02.016. Epub 2017 Mar 1.

PMID:
28259766
40.

Influence of the cooling rate and the blend ratio on the physical stability of co-amorphous naproxen/indomethacin.

Beyer A, Grohganz H, Löbmann K, Rades T, Leopold CS.

Eur J Pharm Biopharm. 2016 Dec;109:140-148. doi: 10.1016/j.ejpb.2016.10.002. Epub 2016 Oct 13.

PMID:
27746228
41.

Erratum to: Racial disparities in all-cause mortality among younger commercially insured women with incident metastatic breast cancer.

Leopold C, Wagner AK, Zhang F, Lu CY, Earle C, Nekhlyudov L, Ross-Degnan D, Wharam JF.

Breast Cancer Res Treat. 2016 Nov;160(2):385. No abstract available.

42.
43.

Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover.

Grumet L, Eichmann TO, Taschler U, Zierler KA, Leopold C, Moustafa T, Radovic B, Romauch M, Yan C, Du H, Haemmerle G, Zechner R, Fickert P, Kratky D, Zimmermann R, Lass A.

J Biol Chem. 2016 Aug 19;291(34):17977-87. doi: 10.1074/jbc.M116.724054. Epub 2016 Jun 27.

44.

Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism.

Sachdev V, Leopold C, Bauer R, Patankar JV, Iqbal J, Obrowsky S, Boverhof R, Doktorova M, Scheicher B, Goeritzer M, Kolb D, Turnbull AV, Zimmer A, Hoefler G, Hussain MM, Groen AK, Kratky D.

Biochim Biophys Acta. 2016 Sep;1861(9 Pt A):1132-1141. doi: 10.1016/j.bbalip.2016.06.014. Epub 2016 Jun 23.

45.

Racial disparities in all-cause mortality among younger commercially insured women with incident metastatic breast cancer.

Leopold C, Wagner AK, Zhang F, Lu CY, Earle C, Nekhlyudov L, Ross-Degnan D, Wharam JF.

Breast Cancer Res Treat. 2016 Jul;158(2):333-40. doi: 10.1007/s10549-016-3875-z. Epub 2016 Jun 24. Erratum in: Breast Cancer Res Treat. 2016 Nov;160(2):385.

46.

Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice.

Radović B, Vujić N, Leopold C, Schlager S, Goeritzer M, Patankar JV, Korbelius M, Kolb D, Reindl J, Wegscheider M, Tomin T, Birner-Gruenberger R, Schittmayer M, Groschner L, Magnes C, Diwoky C, Frank S, Steyrer E, Du H, Graier WF, Madl T, Kratky D.

Diabetologia. 2016 Aug;59(8):1743-52. doi: 10.1007/s00125-016-3968-6. Epub 2016 May 6.

47.

Preparation and recrystallization behavior of spray-dried co-amorphous naproxen-indomethacin.

Beyer A, Radi L, Grohganz H, Löbmann K, Rades T, Leopold CS.

Eur J Pharm Biopharm. 2016 Jul;104:72-81. doi: 10.1016/j.ejpb.2016.04.019. Epub 2016 Apr 26.

PMID:
27130786
48.

Thirty Years of Media Coverage on High Drug Prices in the United States--A Never-Ending Story or a Time for Change?

Leopold C, Chambers JD, Wagner AK.

Value Health. 2016 Jan;19(1):14-6. doi: 10.1016/j.jval.2015.10.008. Epub 2015 Dec 2.

49.

Rapid Assessment of Tablet Film Coating Quality by Multispectral UV Imaging.

Klukkert M, Wu JX, Rantanen J, Rehder S, Carstensen JM, Rades T, Leopold CS.

AAPS PharmSciTech. 2016 Aug;17(4):958-67. doi: 10.1208/s12249-015-0414-x. Epub 2015 Oct 13.

PMID:
26729525
50.

Multispectral UV imaging for fast and non-destructive quality control of chemical and physical tablet attributes.

Klukkert M, Wu JX, Rantanen J, Carstensen JM, Rades T, Leopold CS.

Eur J Pharm Sci. 2016 Jul 30;90:85-95. doi: 10.1016/j.ejps.2015.12.004. Epub 2015 Dec 3.

PMID:
26657202

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