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Items: 25


Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation.

Villoslada P, Vila G, Colafrancesco V, Moreno B, Fernandez-Diez B, Vazquez R, Pertsovskaya I, Zubizarreta I, Pulido-Valdeolivas I, Messeguer J, Vendrell-Navarro G, Frade JM, López-Sánchez N, Teixido M, Giralt E, Masso M, Dugas JC, Leonoudakis D, Lariosa-Willingham KD, Steinman L, Messeguer A.

Neurotherapeutics. 2019 Jul;16(3):808-827. doi: 10.1007/s13311-019-00717-4.


A Central Nervous System Axonal Myelination Assay for High-Throughput Screening.

Lariosa-Willingham K, Leonoudakis D.

Methods Mol Biol. 2018;1791:179-192. doi: 10.1007/978-1-4939-7862-5_14.


Anti-Inflammatory and Neuroprotective Role of Natural Product Securinine in Activated Glial Cells: Implications for Parkinson's Disease.

Leonoudakis D, Rane A, Angeli S, Lithgow GJ, Andersen JK, Chinta SJ.

Mediators Inflamm. 2017;2017:8302636. doi: 10.1155/2017/8302636. Epub 2017 Apr 4.


Development of a high throughput drug screening assay to identify compounds that protect oligodendrocyte viability and differentiation under inflammatory conditions.

Lariosa-Willingham KD, Rosler ES, Tung JS, Dugas JC, Collins TL, Leonoudakis D.

BMC Res Notes. 2016 Sep 5;9(1):444. doi: 10.1186/s13104-016-2219-8.


A high throughput drug screening assay to identify compounds that promote oligodendrocyte differentiation using acutely dissociated and purified oligodendrocyte precursor cells.

Lariosa-Willingham KD, Rosler ES, Tung JS, Dugas JC, Collins TL, Leonoudakis D.

BMC Res Notes. 2016 Sep 5;9(1):419. doi: 10.1186/s13104-016-2220-2.


Development of a central nervous system axonal myelination assay for high throughput screening.

Lariosa-Willingham KD, Rosler ES, Tung JS, Dugas JC, Collins TL, Leonoudakis D.

BMC Neurosci. 2016 Apr 22;17:16. doi: 10.1186/s12868-016-0250-2.


CNS myelin wrapping is driven by actin disassembly.

Zuchero JB, Fu MM, Sloan SA, Ibrahim A, Olson A, Zaremba A, Dugas JC, Wienbar S, Caprariello AV, Kantor C, Leonoudakis D, Lariosa-Willingham K, Kronenberg G, Gertz K, Soderling SH, Miller RH, Barres BA.

Dev Cell. 2015 Jul 27;34(2):152-67. doi: 10.1016/j.devcel.2015.06.011. Epub 2015 Jul 9. Erratum in: Dev Cell. 2015 Sep 14;34(5):608. Leonoudakus, Dmitri [corrected to Leonoudakis, Dmitri].


Discovery and Characterization of Nonpeptidyl Agonists of the Tissue-Protective Erythropoietin Receptor.

Miller JL, Church TJ, Leonoudakis D, Lariosa-Willingham K, Frigon NL, Tettenborn CS, Spencer JR, Punnonen J.

Mol Pharmacol. 2015 Aug;88(2):357-67. doi: 10.1124/mol.115.098400. Epub 2015 May 27.


Endocytic trafficking of laminin is controlled by dystroglycan and is disrupted in cancers.

Leonoudakis D, Huang G, Akhavan A, Fata JE, Singh M, Gray JW, Muschler JL.

J Cell Sci. 2014 Nov 15;127(Pt 22):4894-903. doi: 10.1242/jcs.152728. Epub 2014 Sep 12.


Loss of cell-surface laminin anchoring promotes tumor growth and is associated with poor clinical outcomes.

Akhavan A, Griffith OL, Soroceanu L, Leonoudakis D, Luciani-Torres MG, Daemen A, Gray JW, Muschler JL.

Cancer Res. 2012 May 15;72(10):2578-88. doi: 10.1158/0008-5472.CAN-11-3732.


Dystroglycan controls signaling of multiple hormones through modulation of STAT5 activity.

Leonoudakis D, Singh M, Mohajer R, Mohajer P, Fata JE, Campbell KP, Muschler JL.

J Cell Sci. 2010 Nov 1;123(Pt 21):3683-92. doi: 10.1242/jcs.070680. Epub 2010 Oct 12.


Cannabinoid receptor activation reduces TNFalpha-induced surface localization of AMPAR-type glutamate receptors and excitotoxicity.

Zhao P, Leonoudakis D, Abood ME, Beattie EC.

Neuropharmacology. 2010 Feb;58(2):551-8. doi: 10.1016/j.neuropharm.2009.07.035. Epub 2009 Aug 4.


Real-time imaging of discrete exocytic events mediating surface delivery of AMPA receptors.

Yudowski GA, Puthenveedu MA, Leonoudakis D, Panicker S, Thorn KS, Beattie EC, von Zastrow M.

J Neurosci. 2007 Oct 10;27(41):11112-21.


TNFalpha-induced AMPA-receptor trafficking in CNS neurons; relevance to excitotoxicity?

Leonoudakis D, Braithwaite SP, Beattie MS, Beattie EC.

Neuron Glia Biol. 2004 Aug;1(3):263-73.


Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.

Leonoudakis D, Conti LR, Anderson S, Radeke CM, McGuire LM, Adams ME, Froehner SC, Yates JR 3rd, Vandenberg CA.

J Biol Chem. 2004 May 21;279(21):22331-46. Epub 2004 Mar 15.


A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.

Leonoudakis D, Conti LR, Radeke CM, McGuire LM, Vandenberg CA.

J Biol Chem. 2004 Apr 30;279(18):19051-63. Epub 2004 Feb 11.


Inward rectifier potassium channel Kir2.2 is associated with synapse-associated protein SAP97.

Leonoudakis D, Mailliard W, Wingerd K, Clegg D, Vandenberg C.

J Cell Sci. 2001 Mar;114(Pt 5):987-98.


Baseline K+ channels as targets of general anesthetics: studies of the action of volatile anesthetics on TOK1.

Yost CS, Gray AT, Winegar BD, Leonoudakis D.

Toxicol Lett. 1998 Nov 23;100-101:293-300. Review.


Oleamide potentiates benzodiazepine-sensitive gamma-aminobutyric acid receptor activity but does not alter minimum alveolar anesthetic concentration.

Yost CS, Hampson AJ, Leonoudakis D, Koblin DD, Bornheim LM, Gray AT.

Anesth Analg. 1998 Jun;86(6):1294-300.


TOK1 is a volatile anesthetic stimulated K+ channel.

Gray AT, Winegar BD, Leonoudakis DJ, Forsayeth JR, Yost CS.

Anesthesiology. 1998 Apr;88(4):1076-84.


An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum.

Leonoudakis D, Gray AT, Winegar BD, Kindler CH, Harada M, Taylor DM, Chavez RA, Forsayeth JR, Yost CS.

J Neurosci. 1998 Feb 1;18(3):868-77.


Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission.

Hampson AJ, Bornheim LM, Scanziani M, Yost CS, Gray AT, Hansen BM, Leonoudakis DJ, Bickler PE.

J Neurochem. 1998 Feb;70(2):671-6.


An active-site histidine of NR1/2C mediates voltage-independent inhibition by zinc.

Gray AT, Leonoudakis DJ, Yost CS.

Brain Res Mol Brain Res. 1997 Dec 1;52(1):157-61.


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