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Cardiovascular magnetic resonance left ventricular strain in end-stage renal disease patients after kidney transplantation.

Gong IY, Al-Amro B, Prasad GVR, Connelly PW, Wald RM, Wald R, Deva DP, Leong-Poi H, Nash MM, Yuan W, Gunaratnam L, Kim SJ, Lok CE, Connelly KA, Yan AT.

J Cardiovasc Magn Reson. 2018 Dec 17;20(1):83. doi: 10.1186/s12968-018-0504-5.


Jack of many trades: Multifaceted role of neuropilins in pancreatic cancer.

Matkar PN, Jong ED, Ariyagunarajah R, Prud'homme GJ, Singh KK, Leong-Poi H.

Cancer Med. 2018 Oct;7(10):5036-5046. doi: 10.1002/cam4.1715. Epub 2018 Sep 14. Review.


Valproic Acid Induces Endothelial-to-Mesenchymal Transition-Like Phenotypic Switching.

Murugavel S, Bugyei-Twum A, Matkar PN, Al-Mubarak H, Chen HH, Adam M, Jain S, Narang T, Abdin RM, Qadura M, Connelly KA, Leong-Poi H, Singh KK.

Front Pharmacol. 2018 Jul 11;9:737. doi: 10.3389/fphar.2018.00737. eCollection 2018.


Lung Ultrasound and Microbubbles Enhance Aminoglycoside Efficacy and Delivery to the Lung in Escherichia coli-induced Pneumonia and Acute Respiratory Distress Syndrome.

Sugiyama MG, Mintsopoulos V, Raheel H, Goldenberg NM, Batt JE, Brochard L, Kuebler WM, Leong-Poi H, Karshafian R, Lee WL.

Am J Respir Crit Care Med. 2018 Aug 1;198(3):404-408. doi: 10.1164/rccm.201711-2259LE. No abstract available.


Clinical Applications of Ultrasonic Enhancing Agents in Echocardiography: 2018 American Society of Echocardiography Guidelines Update.

Porter TR, Mulvagh SL, Abdelmoneim SS, Becher H, Belcik JT, Bierig M, Choy J, Gaibazzi N, Gillam LD, Janardhanan R, Kutty S, Leong-Poi H, Lindner JR, Main ML, Mathias W Jr, Park MM, Senior R, Villanueva F.

J Am Soc Echocardiogr. 2018 Mar;31(3):241-274. doi: 10.1016/j.echo.2017.11.013. No abstract available.


Evaluation of left ventricular reverse remodeling in patients with severe aortic regurgitation undergoing aortic valve replacement: Comparison between diameters and volumes.

Ong G, Redfors B, Crowley A, Abdel-Qadir H, Harrington A, Liu Y, Lafrenière-Roula M, Leong-Poi H, Peterson MD, Connelly KA.

Echocardiography. 2018 Feb;35(2):142-147. doi: 10.1111/echo.13750. Epub 2017 Nov 28.


Friends Turned Foes: Angiogenic Growth Factors beyond Angiogenesis.

Matkar PN, Ariyagunarajah R, Leong-Poi H, Singh KK.

Biomolecules. 2017 Oct 2;7(4). pii: E74. doi: 10.3390/biom7040074. Review.


Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia.

Yougbaré I, Tai WS, Zdravic D, Oswald BE, Lang S, Zhu G, Leong-Poi H, Qu D, Yu L, Dunk C, Zhang J, Sled JG, Lye SJ, Brkić J, Peng C, Höglund P, Croy BA, Adamson SL, Wen XY, Stewart DJ, Freedman J, Ni H.

Nat Commun. 2017 Aug 9;8(1):224. doi: 10.1038/s41467-017-00269-1.


Randomised trial of mitral valve repair with leaflet resection versus leaflet preservation on functional mitral stenosis (The CAMRA CardioLink-2 Trial).

Chan V, Chu MWA, Leong-Poi H, Latter DA, Hall J, Thorpe KE, de Varennes BE, Quan A, Tsang W, Dhingra N, Yared K, Teoh H, Chu FV, Chan KL, Mesana TG, Connelly KA, Ruel M, Jüni P, Mazer CD, Verma S.

BMJ Open. 2017 May 30;7(5):e015032. doi: 10.1136/bmjopen-2016-015032.


Echocardiographic Assessment of Young Male Draft-Eligible Elite Hockey Players Invited to the Medical and Fitness Combine by the National Hockey League.

Ong G, Connelly KA, Goodman J, Leong-Poi H, Evangelista V, Levitt K, Gledhill N, Jamnik V, Gledhill S, Yan AT, Chan KL, Chow CM.

Am J Cardiol. 2017 Jun 15;119(12):2088-2092. doi: 10.1016/j.amjcard.2017.03.042. Epub 2017 Mar 29.


Cardiovascular inflammation is reduced with methotrexate in diabetes.

Quan A, Pan Y, Singh KK, Polemidiotis J, Teoh H, Leong-Poi H, Verma S.

Mol Cell Biochem. 2017 Aug;432(1-2):159-167. doi: 10.1007/s11010-017-3006-0. Epub 2017 Mar 16.


Relationships Between Left Ventricular Structure and Function According to Cardiac MRI and Cardiac Biomarkers in End-Stage Renal Disease.

Ross BA, Wald R, Goldstein MB, Yuen DA, Leipsic J, Kiaii M, Rathe A, Deva DP, Kirpalani A, Bello OO, Graham JJ, Leong-Poi H, Connelly KA, Yan AT.

Can J Cardiol. 2017 Apr;33(4):501-507. doi: 10.1016/j.cjca.2016.11.021. Epub 2016 Dec 3.


Cardiac Overexpression of S100A6 Attenuates Cardiomyocyte Apoptosis and Reduces Infarct Size After Myocardial Ischemia-Reperfusion.

Mofid A, Newman NS, Lee PJ, Abbasi C, Matkar PN, Rudenko D, Kuliszewski MA, Chen HH, Afrasiabi K, Tsoporis JN, Gramolini AO, Connelly KA, Parker TG, Leong-Poi H.

J Am Heart Assoc. 2017 Feb 7;6(2). pii: e004738. doi: 10.1161/JAHA.116.004738.


Controversies in quantification of mitral valve regurgitation: role of cardiac magnetic resonance imaging.

Connelly KA, Ho EC, Leong-Poi H.

Curr Opin Cardiol. 2017 Mar;32(2):152-160. doi: 10.1097/HCO.0000000000000363. Review.


Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma.

Matkar PN, Singh KK, Rudenko D, Kim YJ, Kuliszewski MA, Prud'homme GJ, Hedley DW, Leong-Poi H.

Oncotarget. 2016 Oct 25;7(43):69489-69506. doi: 10.18632/oncotarget.11060.


New device for temporary hemorrhage control in penetrating injuries to the ventricles.

Rezende-Neto JB, Leong-Poi H, Rizoli S, Beckett A.

Trauma Surg Acute Care Open. 2016 Jul 24;1(1):e000012. doi: 10.1136/tsaco-2016-000012. eCollection 2016.


Contrast Ultrasound Ischemic Memory Imaging: Path to Clinical Translation.

Leong-Poi H.

JACC Cardiovasc Imaging. 2016 Aug;9(8):947-9. doi: 10.1016/j.jcmg.2015.12.021. Epub 2016 Jun 15. No abstract available.


Cardiac gene therapy: are we there yet?

Matkar PN, Leong-Poi H, Singh KK.

Gene Ther. 2016 Aug;23(8-9):635-48. doi: 10.1038/gt.2016.43. Epub 2016 Apr 29. Review.


Prospect of ultrasound-mediated gene delivery in cardiovascular applications.

Chen HH, Matkar PN, Afrasiabi K, Kuliszewski MA, Leong-Poi H.

Expert Opin Biol Ther. 2016 Jun;16(6):815-26. doi: 10.1517/14712598.2016.1169268. Epub 2016 Apr 11. Review.


Microbubbles and Ultrasound: Therapeutic Applications in Diabetic Nephropathy.

Cao WJ, Matkar PN, Chen HH, Mofid A, Leong-Poi H.

Adv Exp Med Biol. 2016;880:309-30. doi: 10.1007/978-3-319-22536-4_17. Review.


The Association Between Conversion to In-centre Nocturnal Hemodialysis and Left Ventricular Mass Regression in Patients With End-Stage Renal Disease.

Wald R, Goldstein MB, Perl J, Kiaii M, Yuen D, Wald RM, Harel Z, Weinstein JJ, Jakubovic B, Leong-Poi H, Kirpalani A, Leipsic J, Dacouris N, Wolf M, Yan AT.

Can J Cardiol. 2016 Mar;32(3):369-77. doi: 10.1016/j.cjca.2015.07.004. Epub 2015 Jul 9.


Therapeutic Angiogenesis by Ultrasound-Mediated MicroRNA-126-3p Delivery.

Cao WJ, Rosenblat JD, Roth NC, Kuliszewski MA, Matkar PN, Rudenko D, Liao C, Lee PJ, Leong-Poi H.

Arterioscler Thromb Vasc Biol. 2015 Nov;35(11):2401-11. doi: 10.1161/ATVBAHA.115.306506. Epub 2015 Sep 17.


Early outgrowth pro-angiogenic cell number and function do not correlate with left ventricular structure and function in conventional hemodialysis patients: a cross-sectional study.

Lineen JR, Kuliszewski M, Dacouris N, Liao C, Rudenko D, Deva DP, Goldstein M, Leong-Poi H, Wald R, Yan AT, Yuen DA.

Can J Kidney Health Dis. 2015 Jul 30;2:25. doi: 10.1186/s40697-015-0060-y. eCollection 2015.


Effects of long-term chloroquine administration on the natural history of aortic aneurysms in mice.

Ramadan A, Wheatcroft MD, Quan A, Singh KK, Lovren F, Dhingra N, Teoh H, Al-Omran M, Leong-Poi H, Verma S.

Can J Physiol Pharmacol. 2015 Aug;93(8):641-8. doi: 10.1139/cjpp-2015-0068. Epub 2015 Mar 20.


The Tie2-agonist Vasculotide rescues mice from influenza virus infection.

Sugiyama MG, Armstrong SM, Wang C, Hwang D, Leong-Poi H, Advani A, Advani S, Zhang H, Szaszi K, Tabuchi A, Kuebler WM, Van Slyke P, Dumont DJ, Lee WL.

Sci Rep. 2015 Jun 5;5:11030. doi: 10.1038/srep11030.


Maternal anti-platelet β3 integrins impair angiogenesis and cause intracranial hemorrhage.

Yougbaré I, Lang S, Yang H, Chen P, Zhao X, Tai WS, Zdravic D, Vadasz B, Li C, Piran S, Marshall A, Zhu G, Tiller H, Killie MK, Boyd S, Leong-Poi H, Wen XY, Skogen B, Adamson SL, Freedman J, Ni H.

J Clin Invest. 2015 Apr;125(4):1545-56. doi: 10.1172/JCI77820. Epub 2015 Mar 16.


Perlecan heparan sulfate proteoglycan is a critical determinant of angiogenesis in response to mouse hind-limb ischemia.

Qiang B, Lim SY, Lekas M, Kuliszewski MA, Wolff R, Osherov AB, Rudenko D, Leong-Poi H, Noyan H, Husain M, Tran K, Tryggvason K, Hedin U, Tran-Lundmark K, Strauss BH.

Can J Cardiol. 2014 Nov;30(11):1444-51. doi: 10.1016/j.cjca.2014.06.003. Epub 2014 Jun 12.


Battle of the bulge: the yin and yang of vascular endothelial growth factor in obesity.

Leong-Poi H.

Circulation. 2014 Sep 23;130(13):1034-6. doi: 10.1161/CIRCULATIONAHA.114.012098. Epub 2014 Aug 12. No abstract available.


A modified portfolio diet complements medical management to reduce cardiovascular risk factors in diabetic patients with coronary artery disease.

Keith M, Kuliszewski MA, Liao C, Peeva V, Ahmed M, Tran S, Sorokin K, Jenkins DJ, Errett L, Leong-Poi H.

Clin Nutr. 2015 Jun;34(3):541-8. doi: 10.1016/j.clnu.2014.06.010. Epub 2014 Jun 28.


Survivin gene therapy attenuates left ventricular systolic dysfunction in doxorubicin cardiomyopathy by reducing apoptosis and fibrosis.

Lee PJ, Rudenko D, Kuliszewski MA, Liao C, Kabir MG, Connelly KA, Leong-Poi H.

Cardiovasc Res. 2014 Mar 1;101(3):423-33. doi: 10.1093/cvr/cvu001. Epub 2014 Jan 8.


Routine versus selective cardiac magnetic resonance in non-ischemic heart failure - OUTSMART-HF: study protocol for a randomized controlled trial (IMAGE-HF (heart failure) project 1-B).

Paterson I, Wells GA, Ezekowitz JA, White JA, Friedrich MG, Mielniczuk LM, O'Meara E, Chow B, DeKemp RA, Klein R, Dennie C, Dick A, Coyle D, Dwivedi G, Rajda M, Wright GA, Laine M, Hanninen H, Larose E, Connelly KA, Leong-Poi H, Howarth AG, Davies RA, Duchesne L, Yla-Herttuala S, Saraste A, Farand P, Garrard L, Tardif JC, Arnold M, Knuuti J, Beanlands R, Chan KL.

Trials. 2013 Oct 12;14:332. doi: 10.1186/1745-6215-14-332.


Anti-inflammatory and pro-angiogenic effects of beta blockers in a canine model of chronic ischemic cardiomyopathy: comparison between carvedilol and metoprolol.

Le DE, Pascotto M, Leong-Poi H, Sari I, Micari A, Kaul S.

Basic Res Cardiol. 2013 Nov;108(6):384. doi: 10.1007/s00395-013-0384-7. Epub 2013 Sep 27.


Conditional cardiac overexpression of S100A6 attenuates myocyte hypertrophy and apoptosis following myocardial infarction.

Tsoporis JT, Izhar S, Desjardins JF, Leong-Poi H, Parker TG.

Curr Pharm Des. 2014;20(12):1941-9.


Optimization of Ultrasound-mediated Anti-angiogenic Cancer Gene Therapy.

Fujii H, Matkar P, Liao C, Rudenko D, Lee PJ, Kuliszewski MA, Prud'homme GJ, Leong-Poi H.

Mol Ther Nucleic Acids. 2013 May 21;2:e94. doi: 10.1038/mtna.2013.20.


Quantitative assessment of brain microvascular and tissue oxygenation during cardiac arrest and resuscitation in pigs.

Yu J, Ramadeen A, Tsui AK, Hu X, Zou L, Wilson DF, Esipova TV, Vinogradov SA, Leong-Poi H, Zamiri N, Mazer CD, Dorian P, Hare GM.

Anaesthesia. 2013 Jul;68(7):723-35. doi: 10.1111/anae.12227. Epub 2013 Apr 17.


Dronedarone and Captisol-enabled amiodarone in an experimental cardiac arrest.

Glover BM, Hu X, Aves T, Ramadeen A, Zou L, Leong-Poi H, Fujii H, Dorian P.

J Cardiovasc Pharmacol. 2013 May;61(5):385-90. doi: 10.1097/FJC.0b013e3182868750.


American Society of Echocardiography Cardiovascular Technology and Research Summit: a roadmap for 2020.

Pellikka PA, Douglas PS, Miller JG, Abraham TP, Baumann R, Buxton DB, Byrd BF 3rd, Chen P, Cook NL, Gardin JM, Hansen G, Houle HC, Husson S, Kaul S, Klein AL, Lang RM, Leong-Poi H, Lopez H, Mahmoud TM, Maslak S, McCulloch ML, Metz S, Nagueh SF, Pearlman AS, Pibarot P, Picard MH, Porter TR, Prater D, Rodriguez R, Sarano ME, Scherrer-Crosbie M, Shirali GS, Sinusas A, Slosky JJ, Sugeng L, Tatpati A, Villanueva FS, von Ramm OT, Weissman NJ, Zamani S.

J Am Soc Echocardiogr. 2013 Apr;26(4):325-38. doi: 10.1016/j.echo.2013.02.003. No abstract available.


Standards for provision and accreditation of echocardiography in Ontario.

Sanfilippo AJ, Chan KL, Hughes WG, Kingsbury KJ, Leong-Poi H, Sasson Z, Wald R; Ontario Ministry of Health and Long-term Care and Ontario Medical Association.

Can J Cardiol. 2013 Mar;29(3):396-8. doi: 10.1016/j.cjca.2012.11.024.


Treatment with a highly selective β₁ antagonist causes dose-dependent impairment of cerebral perfusion after hemodilution in rats.

Hu T, Beattie WS, Mazer CD, Leong-Poi H, Fujii H, Wilson DF, Tsui AK, Liu E, Muhammad M, Baker AJ, Hare GM.

Anesth Analg. 2013 Mar;116(3):649-62. doi: 10.1213/ANE.0b013e318280e26d. Epub 2013 Feb 11.


Echocardiography and vascular ultrasound: new developments and future directions.

Ducas R, Tsang W, Chong AA, Jassal DS, Lang RM, Leong-Poi H, Chan KL.

Can J Cardiol. 2013 Mar;29(3):304-16. doi: 10.1016/j.cjca.2012.11.001. Epub 2013 Jan 17. Review.


Ultrasound-mediated vascular gene transfection by cavitation of endothelial-targeted cationic microbubbles.

Xie A, Belcik T, Qi Y, Morgan TK, Champaneri SA, Taylor S, Davidson BP, Zhao Y, Klibanov AL, Kuliszewski MA, Leong-Poi H, Ammi A, Lindner JR.

JACC Cardiovasc Imaging. 2012 Dec;5(12):1253-62. doi: 10.1016/j.jcmg.2012.05.017.


A direct comparison of endothelial progenitor cell dysfunction in rat metabolic syndrome and diabetes.

Kuliszewski MA, Ward MR, Kowalewski JW, Smith AH, Stewart DJ, Kutryk MJ, Leong-Poi H.

Atherosclerosis. 2013 Jan;226(1):58-66. doi: 10.1016/j.atherosclerosis.2012.09.029. Epub 2012 Oct 10.


Comparative assessment of 2-dimensional echocardiography vs cardiac magnetic resonance imaging in measuring left ventricular mass in patients with and without end-stage renal disease.

Jakubovic BD, Wald R, Goldstein MB, Leong-Poi H, Yuen DA, Perl J, Lima JA, Liu JJ, Kirpalani A, Dacouris N, Wald R, Connelly KA, Yan AT.

Can J Cardiol. 2013 Mar;29(3):384-90. doi: 10.1016/j.cjca.2012.07.013. Epub 2012 Oct 25.


Contrast ultrasound and targeted microbubbles: diagnostic and therapeutic applications in progressive diabetic nephropathy.

Leong-Poi H.

Semin Nephrol. 2012 Sep;32(5):494-504. doi: 10.1016/j.semnephrol.2012.07.013. Review.


Potential clinical impact of cardiovascular magnetic resonance assessment of ejection fraction on eligibility for cardioverter defibrillator implantation.

Joshi SB, Connelly KA, Jimenez-Juan L, Hansen M, Kirpalani A, Dorian P, Mangat I, Al-Hesayen A, Crean AM, Wright GA, Yan AT, Leong-Poi H.

J Cardiovasc Magn Reson. 2012 Oct 8;14:69. doi: 10.1186/1532-429X-14-69.


S100B: role in cardiac remodeling and function following myocardial infarction in diabetes.

Mohammadzadeh F, Desjardins JF, Tsoporis JN, Proteau G, Leong-Poi H, Parker TG.

Life Sci. 2013 Mar 28;92(11):639-47. doi: 10.1016/j.lfs.2012.09.011. Epub 2012 Sep 20.


Docosahexaenoic acid, but not eicosapentaenoic acid, supplementation reduces vulnerability to atrial fibrillation.

Ramadeen A, Connelly KA, Leong-Poi H, Hu X, Fujii H, Laurent G, Domenichiello AF, Bazinet RP, Dorian P.

Circ Arrhythm Electrophysiol. 2012 Oct;5(5):978-83. doi: 10.1161/CIRCEP.112.971515. Epub 2012 Aug 24.


Salutary effect of resveratrol on sepsis-induced myocardial depression.

Smeding L, Leong-Poi H, Hu P, Shan Y, Haitsma JJ, Horvath E, Furmli S, Masoom H, Kuiper JW, Slutsky AS, Parker TG, Plötz FB, dos Santos CC.

Crit Care Med. 2012 Jun;40(6):1896-907. doi: 10.1097/CCM.0b013e31824e1370.


Statin therapy prevents expansive remodeling in venous bypass grafts.

Qiang B, Toma J, Fujii H, Osherov AB, Nili N, Sparkes JD, Fefer P, Samuel M, Butany J, Leong-Poi H, Strauss BH.

Atherosclerosis. 2012 Jul;223(1):106-13. doi: 10.1016/j.atherosclerosis.2012.03.013. Epub 2012 Mar 22.


Sustained improvement in perfusion and flow reserve after temporally separated delivery of vascular endothelial growth factor and angiopoietin-1 plasmid deoxyribonucleic acid.

Smith AH, Kuliszewski MA, Liao C, Rudenko D, Stewart DJ, Leong-Poi H.

J Am Coll Cardiol. 2012 Apr 3;59(14):1320-8. doi: 10.1016/j.jacc.2011.12.025.

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