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Items: 1 to 50 of 139

1.

Stiffness and Anisotropy Effect on Shear Wave Elastography: A Phantom and in Vivo Renal Study.

Leong SS, Wong JHD, Md Shah MN, Vijayananthan A, Jalalonmuhali M, Mohd Sharif NH, Abas NK, Ng KH.

Ultrasound Med Biol. 2020 Jan;46(1):34-45. doi: 10.1016/j.ultrasmedbio.2019.08.011. Epub 2019 Oct 5.

PMID:
31594681
2.

Engineering Yarrowia lipolytica towards food waste bioremediation: Production of fatty acid ethyl esters from vegetable cooking oil.

Ng TK, Yu AQ, Ling H, Pratomo Juwono NK, Choi WJ, Leong SSJ, Chang MW.

J Biosci Bioeng. 2020 Jan;129(1):31-40. doi: 10.1016/j.jbiosc.2019.06.009. Epub 2019 Jul 15.

PMID:
31320262
3.

Comparison of Shear Wave Elastography and Conventional Ultrasound in Assessing Kidney Function as Measured Using 51Cr-ethylenediaminetetraacetic Acid and 99Tc-Dimercaptosuccinic Acid.

Leong SS, Wong JHD, Md Shah MN, Vijayananthan A, Jalalonmuhali M, Ng KH.

Ultrasound Med Biol. 2019 Jun;45(6):1417-1426. doi: 10.1016/j.ultrasmedbio.2019.01.024. Epub 2019 Apr 5.

PMID:
30962016
4.

An oleaginous yeast platform for renewable 1-butanol synthesis based on a heterologous CoA-dependent pathway and an endogenous pathway.

Yu A, Zhao Y, Pang Y, Hu Z, Zhang C, Xiao D, Chang MW, Leong SSJ.

Microb Cell Fact. 2018 Oct 25;17(1):166. doi: 10.1186/s12934-018-1014-8.

5.

Synthetic biology toolkits and applications in Saccharomyces cerevisiae.

Chen B, Lee HL, Heng YC, Chua N, Teo WS, Choi WJ, Leong SSJ, Foo JL, Chang MW.

Biotechnol Adv. 2018 Nov 15;36(7):1870-1881. doi: 10.1016/j.biotechadv.2018.07.005. Epub 2018 Jul 18. Review.

PMID:
30031049
6.

Shear wave elastography in the evaluation of renal parenchymal stiffness in patients with chronic kidney disease.

Leong SS, Wong JHD, Md Shah MN, Vijayananthan A, Jalalonmuhali M, Ng KH.

Br J Radiol. 2018 Sep;91(1089):20180235. doi: 10.1259/bjr.20180235. Epub 2018 Jun 21.

7.

Anhydrous polymer-based coating with sustainable controlled release functionality for facile, efficacious impregnation, and delivery of antimicrobial peptides.

Lim K, Saravanan R, Chong KKL, Goh SHM, Chua RRY, Tambyah PA, Chang MW, Kline KA, Leong SSJ.

Biotechnol Bioeng. 2018 Aug;115(8):2000-2012. doi: 10.1002/bit.26713. Epub 2018 Apr 27.

PMID:
29665026
8.

An in-vitro urinary catheterization model that approximates clinical conditions for evaluation of innovations to prevent catheter-associated urinary tract infections.

Chua RYR, Lim K, Leong SSJ, Tambyah PA, Ho B.

J Hosp Infect. 2017 Sep;97(1):66-73. doi: 10.1016/j.jhin.2017.05.006. Epub 2017 May 17.

PMID:
28526271
9.
10.

Observer performance in characterization of carotid plaque texture and surface characteristics with 3D versus 2D ultrasound.

Leong SS, Vijayananthan A, Yaakup NA, Shah N, Ng KH, Acharya UR, Bilgen M.

Comput Biol Med. 2016 Nov 1;78:58-64. doi: 10.1016/j.compbiomed.2016.09.006. Epub 2016 Sep 12.

PMID:
27658262
11.

Genetic Engineering of an Unconventional Yeast for Renewable Biofuel and Biochemical Production.

Yu AQ, Pratomo N, Ng TK, Ling H, Cho HS, Leong SS, Chang MW.

J Vis Exp. 2016 Sep 20;(115). doi: 10.3791/54371.

12.

Metabolic engineering of Saccharomyces cerevisiae for the overproduction of short branched-chain fatty acids.

Yu AQ, Pratomo Juwono NK, Foo JL, Leong SSJ, Chang MW.

Metab Eng. 2016 Mar;34:36-43. doi: 10.1016/j.ymben.2015.12.005. Epub 2015 Dec 22.

13.

Engineering transcription factors to improve tolerance against alkane biofuels in Saccharomyces cerevisiae.

Ling H, Pratomo Juwono NK, Teo WS, Liu R, Leong SS, Chang MW.

Biotechnol Biofuels. 2015 Dec 30;8:231. doi: 10.1186/s13068-015-0411-z. eCollection 2015.

14.

Whole-cell biocatalytic and de novo production of alkanes from free fatty acids in Saccharomyces cerevisiae.

Foo JL, Susanto AV, Keasling JD, Leong SS, Chang MW.

Biotechnol Bioeng. 2017 Jan;114(1):232-237. doi: 10.1002/bit.25920. Epub 2016 Jan 19.

15.

The Nucleoside Analog BMS-986001 Shows Greater In Vitro Activity against HIV-2 than against HIV-1.

Smith RA, Raugi DN, Wu VH, Leong SS, Parker KM, Oakes MK, Sow PS, Ba S, Seydi M, Gottlieb GS; University of Washington-Dakar HIV-2 Study Group.

Antimicrob Agents Chemother. 2015 Dec;59(12):7437-46. doi: 10.1128/AAC.01326-15. Epub 2015 Sep 21.

16.

Correction: Magnetophoresis of superparamagnetic nanoparticles at low field gradient: hydrodynamic effect.

Leong SS, Ahmad Z, Lim J.

Soft Matter. 2015 Oct 14;11(38):7696. doi: 10.1039/c5sm90159f.

PMID:
26365252
17.

Magnetophoresis of superparamagnetic nanoparticles at low field gradient: hydrodynamic effect.

Leong SS, Ahmad Z, Lim J.

Soft Matter. 2015 Sep 21;11(35):6968-80. doi: 10.1039/c5sm01422k. Epub 2015 Aug 3. Erratum in: Soft Matter. 2015 Oct 14;11(38):7696.

PMID:
26234726
18.

Production of Fatty Acid-derived valuable chemicals in synthetic microbes.

Yu AQ, Pratomo Juwono NK, Leong SS, Chang MW.

Front Bioeng Biotechnol. 2014 Dec 23;2:78. doi: 10.3389/fbioe.2014.00078. eCollection 2014. Review.

19.

Development of a catheter functionalized by a polydopamine peptide coating with antimicrobial and antibiofilm properties.

Lim K, Chua RR, Bow H, Tambyah PA, Hadinoto K, Leong SS.

Acta Biomater. 2015 Mar;15:127-38. doi: 10.1016/j.actbio.2014.12.015. Epub 2014 Dec 23.

PMID:
25541344
20.

Microbial tolerance engineering toward biochemical production: from lignocellulose to products.

Ling H, Teo W, Chen B, Leong SS, Chang MW.

Curr Opin Biotechnol. 2014 Oct;29:99-106. doi: 10.1016/j.copbio.2014.03.005. Epub 2014 Apr 17. Review.

PMID:
24743028
21.

Antimicrobial functionalization of silicone surfaces with engineered short peptides having broad spectrum antimicrobial and salt-resistant properties.

Li X, Li P, Saravanan R, Basu A, Mishra B, Lim SH, Su X, Tambyah PA, Leong SS.

Acta Biomater. 2014 Jan;10(1):258-66. doi: 10.1016/j.actbio.2013.09.009. Epub 2013 Sep 20.

PMID:
24056098
22.

Design of short membrane selective antimicrobial peptides containing tryptophan and arginine residues for improved activity, salt-resistance, and biocompatibility.

Saravanan R, Li X, Lim K, Mohanram H, Peng L, Mishra B, Basu A, Lee JM, Bhattacharjya S, Leong SS.

Biotechnol Bioeng. 2014 Jan;111(1):37-49. doi: 10.1002/bit.25003. Epub 2013 Aug 5.

PMID:
23860860
23.

Immobilization studies of an engineered arginine-tryptophan-rich peptide on a silicone surface with antimicrobial and antibiofilm activity.

Lim K, Chua RR, Saravanan R, Basu A, Mishra B, Tambyah PA, Ho B, Leong SS.

ACS Appl Mater Interfaces. 2013 Jul 10;5(13):6412-22. doi: 10.1021/am401629p. Epub 2013 Jun 28. Erratum in: ACS Appl Mater Interfaces. 2013 Sep 11;5(17):8821.

PMID:
23758173
24.

Directed evolution of an E. coli inner membrane transporter for improved efflux of biofuel molecules.

Foo JL, Leong SS.

Biotechnol Biofuels. 2013 May 21;6(1):81. doi: 10.1186/1754-6834-6-81.

25.

Aspirin and non-aspirin non-steroidal anti-inflammatory drug use and risk of lung cancer.

Lim WY, Chuah KL, Eng P, Leong SS, Lim E, Lim TK, Ng A, Poh WT, Tee A, Teh M, Salim A, Seow A.

Lung Cancer. 2012 Aug;77(2):246-51. doi: 10.1016/j.lungcan.2012.03.005. Epub 2012 Apr 3.

PMID:
22480996
26.

Improvement of biomass properties by pretreatment with ionic liquids for bioconversion process.

Weerachanchai P, Leong SS, Chang MW, Ching CB, Lee JM.

Bioresour Technol. 2012 May;111:453-9. doi: 10.1016/j.biortech.2012.02.023. Epub 2012 Feb 14.

PMID:
22366610
27.

Female reproductive factors, gene polymorphisms in the estrogen metabolism pathway, and risk of lung cancer in Chinese women.

Lim WY, Chen Y, Chuah KL, Eng P, Leong SS, Lim E, Lim TK, Ng A, Poh WT, Tee A, Teh M, Salim A, Seow A.

Am J Epidemiol. 2012 Mar 15;175(6):492-503. doi: 10.1093/aje/kwr332. Epub 2012 Feb 13.

PMID:
22331461
28.

High productivity chromatography refolding process for Hepatitis B Virus X (HBx) protein guided by statistical design of experiment studies.

Basu A, Leong SS.

J Chromatogr A. 2012 Feb 3;1223:64-71. doi: 10.1016/j.chroma.2011.12.037. Epub 2011 Dec 16.

PMID:
22209547
29.

Hollow fiber membrane decorated with Ag/MWNTs: toward effective water disinfection and biofouling control.

Gunawan P, Guan C, Song X, Zhang Q, Leong SS, Tang C, Chen Y, Chan-Park MB, Chang MW, Wang K, Xu R.

ACS Nano. 2011 Dec 27;5(12):10033-40. doi: 10.1021/nn2038725. Epub 2011 Nov 21.

PMID:
22077241
30.

Use of a chondroitin sulfate isomer as an effective and removable dispersant of single-walled carbon nanotubes.

Yan LY, Li W, Mesgari S, Leong SS, Chen Y, Loo LS, Mu Y, Chan-Park MB.

Small. 2011 Oct 4;7(19):2758-68.

PMID:
22039610
31.

The imminent role of protein engineering in synthetic biology.

Foo JL, Ching CB, Chang MW, Leong SS.

Biotechnol Adv. 2012 May-Jun;30(3):541-9. doi: 10.1016/j.biotechadv.2011.09.008. Epub 2011 Sep 21. Review.

PMID:
21963685
32.

Surface activated carbon nanospheres for fast adsorption of silver ions from aqueous solutions.

Song X, Gunawan P, Jiang R, Leong SS, Wang K, Xu R.

J Hazard Mater. 2011 Oct 30;194:162-8. doi: 10.1016/j.jhazmat.2011.07.076. Epub 2011 Aug 5.

PMID:
21862215
33.

Engineering microbes to sense and eradicate Pseudomonas aeruginosa, a human pathogen.

Saeidi N, Wong CK, Lo TM, Nguyen HX, Ling H, Leong SS, Poh CL, Chang MW.

Mol Syst Biol. 2011 Aug 16;7:521. doi: 10.1038/msb.2011.55.

34.

Refolding of proteins from inclusion bodies: rational design and recipes.

Basu A, Li X, Leong SS.

Appl Microbiol Biotechnol. 2011 Oct;92(2):241-51. doi: 10.1007/s00253-011-3513-y. Epub 2011 Aug 7. Review.

PMID:
21822901
35.

A phase II study evaluating the safety and efficacy of an adenovirus-ΔLMP1-LMP2 transduced dendritic cell vaccine in patients with advanced metastatic nasopharyngeal carcinoma.

Chia WK, Wang WW, Teo M, Tai WM, Lim WT, Tan EH, Leong SS, Sun L, Chen JJ, Gottschalk S, Toh HC.

Ann Oncol. 2012 Apr;23(4):997-1005. doi: 10.1093/annonc/mdr341. Epub 2011 Aug 4.

36.

Development of an enzyme-linked immunosorbent assay analytical platform for refolding yield determination of recombinant hepatitis B virus X (HBx) protein.

Basu A, Leong SS.

Anal Biochem. 2011 Nov 1;418(1):155-7. doi: 10.1016/j.ab.2011.07.014. Epub 2011 Jul 22.

PMID:
21806960
37.

Meat consumption and risk of lung cancer among never-smoking women.

Lim WY, Chuah KL, Eng P, Leong SS, Lim E, Lim TK, Ng A, Poh WT, Tee A, Teh M, Salim A, Seow A.

Nutr Cancer. 2011;63(6):850-9. doi: 10.1080/01635581.2011.589961. Epub 2011 Jul 20.

PMID:
21774592
38.

A Phase II study of pazopanib in Asian patients with recurrent/metastatic nasopharyngeal carcinoma.

Lim WT, Ng QS, Ivy P, Leong SS, Singh O, Chowbay B, Gao F, Thng CH, Goh BC, Tan DS, Koh TS, Toh CK, Tan EH.

Clin Cancer Res. 2011 Aug 15;17(16):5481-9. doi: 10.1158/1078-0432.CCR-10-3409. Epub 2011 Jun 28. Erratum in: Clin Cancer Res. 2015 Jul 15;21(14):3358.

39.

Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS).

Fukuoka M, Wu YL, Thongprasert S, Sunpaweravong P, Leong SS, Sriuranpong V, Chao TY, Nakagawa K, Chu DT, Saijo N, Duffield EL, Rukazenkov Y, Speake G, Jiang H, Armour AA, To KF, Yang JC, Mok TS.

J Clin Oncol. 2011 Jul 20;29(21):2866-74. doi: 10.1200/JCO.2010.33.4235. Epub 2011 Jun 13.

PMID:
21670455
40.

A chromatography-focused bioprocess that eliminates soluble aggregation for bioactive production of a new antimicrobial peptide candidate.

Li X, Leong SS.

J Chromatogr A. 2011 Jun 10;1218(23):3654-9. doi: 10.1016/j.chroma.2011.04.017. Epub 2011 Apr 14.

PMID:
21530977
41.

A photopolymerized antimicrobial hydrogel coating derived from epsilon-poly-L-lysine.

Zhou C, Li P, Qi X, Sharif AR, Poon YF, Cao Y, Chang MW, Leong SS, Chan-Park MB.

Biomaterials. 2011 Apr;32(11):2704-12. doi: 10.1016/j.biomaterials.2010.12.040. Epub 2011 Jan 22.

PMID:
21257199
42.

Polymorphisms in inflammatory pathway genes, host factors and lung cancer risk in Chinese female never-smokers.

Lim WY, Chen Y, Ali SM, Chuah KL, Eng P, Leong SS, Lim E, Lim TK, Ng AW, Poh WT, Tee A, Teh M, Salim A, Seow A.

Carcinogenesis. 2011 Apr;32(4):522-9. doi: 10.1093/carcin/bgr006. Epub 2011 Jan 20.

PMID:
21252117
43.

A rational design for hepatitis B virus X protein refolding and bioprocess development guided by second virial coefficient studies.

Basu A, Chen WN, Leong SS.

Appl Microbiol Biotechnol. 2011 Apr;90(1):181-91. doi: 10.1007/s00253-010-3058-5. Epub 2011 Jan 7.

PMID:
21212947
44.

A polycationic antimicrobial and biocompatible hydrogel with microbe membrane suctioning ability.

Li P, Poon YF, Li W, Zhu HY, Yeap SH, Cao Y, Qi X, Zhou C, Lamrani M, Beuerman RW, Kang ET, Mu Y, Li CM, Chang MW, Leong SS, Chan-Park MB.

Nat Mater. 2011 Feb;10(2):149-56. doi: 10.1038/nmat2915. Epub 2010 Dec 12.

PMID:
21151166
45.

A new bioproduction route for a novel antimicrobial peptide.

Tay DK, Rajagopalan G, Li X, Chen Y, Lua LH, Leong SS.

Biotechnol Bioeng. 2011 Mar;108(3):572-81. doi: 10.1002/bit.22970. Epub 2010 Nov 17.

PMID:
20967800
46.

Tethering antimicrobial peptides: current status and potential challenges.

Onaizi SA, Leong SS.

Biotechnol Adv. 2011 Jan-Feb;29(1):67-74. doi: 10.1016/j.biotechadv.2010.08.012. Epub 2010 Sep 9. Review.

PMID:
20817088
47.

iTRAQ-coupled two-dimensional liquid chromatography/tandem mass spectrometric analysis of protein profile in Escherichia coli incubated with human neutrophil peptide 1--potential in antimicrobial strategy.

Zhou YS, Lamrani M, Chan-Park MB, Leong SS, Chang M, Chen WN.

Rapid Commun Mass Spectrom. 2010 Sep;24(18):2787-90. doi: 10.1002/rcm.4712. No abstract available.

PMID:
20814987
48.

Docetaxel is effective in heavily pretreated patients with disseminated nasopharyngeal carcinoma.

Ngeow J, Lim WT, Leong SS, Ang MK, Toh CK, Gao F, Chowbay B, Tan EH.

Ann Oncol. 2011 Mar;22(3):718-22. doi: 10.1093/annonc/mdq425. Epub 2010 Aug 17.

49.

Graft-vs-tumor effect in patients with advanced nasopharyngeal cancer treated with nonmyeloablative allogeneic PBSC transplantation.

Toh HC, Chia WK, Sun L, Thng CH, Soe Y, Phoon YP, Yap SP, Lim WT, Tai WM, Hee SW, Tan SH, Leong SS, Tan EH.

Bone Marrow Transplant. 2011 Apr;46(4):573-9. doi: 10.1038/bmt.2010.161. Epub 2010 Jul 26.

50.

Novel short antibacterial and antifungal peptides with low cytotoxicity: Efficacy and action mechanisms.

Qi X, Zhou C, Li P, Xu W, Cao Y, Ling H, Ning Chen W, Ming Li C, Xu R, Lamrani M, Mu Y, Leong SS, Wook Chang M, Chan-Park MB.

Biochem Biophys Res Commun. 2010 Jul 30;398(3):594-600. doi: 10.1016/j.bbrc.2010.06.131. Epub 2010 Jul 11.

PMID:
20603106

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