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Items: 30


A Potent and Effective Suicidal Listeria Vaccine Platform.

Hanson WG, Benanti EL, Lemmens EE, Liu W, Skoble J, Leong ML, Rae CS, Fassò M, Brockstedt DG, Chen C, Portnoy DA, Dubensky TW Jr, Lauer P.

Infect Immun. 2019 Jul 23;87(8). pii: e00144-19. doi: 10.1128/IAI.00144-19. Print 2019 Aug.


Magnitude of Therapeutic STING Activation Determines CD8+ T Cell-Mediated Anti-tumor Immunity.

Sivick KE, Desbien AL, Glickman LH, Reiner GL, Corrales L, Surh NH, Hudson TE, Vu UT, Francica BJ, Banda T, Katibah GE, Kanne DB, Leong JJ, Metchette K, Bruml JR, Ndubaku CO, McKenna JM, Feng Y, Zheng L, Bender SL, Cho CY, Leong ML, van Elsas A, Dubensky TW Jr, McWhirter SM.

Cell Rep. 2018 Dec 11;25(11):3074-3085.e5. doi: 10.1016/j.celrep.2018.11.047.


Recombinant Listeria promotes tumor rejection by CD8+ T cell-dependent remodeling of the tumor microenvironment.

Deng W, Lira V, Hudson TE, Lemmens EE, Hanson WG, Flores R, Barajas G, Katibah GE, Desbien AL, Lauer P, Leong ML, Portnoy DA, Dubensky TW Jr.

Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8179-8184. doi: 10.1073/pnas.1801910115. Epub 2018 Jul 23.


STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection.

Van Dis E, Sogi KM, Rae CS, Sivick KE, Surh NH, Leong ML, Kanne DB, Metchette K, Leong JJ, Bruml JR, Chen V, Heydari K, Cadieux N, Evans T, McWhirter SM, Dubensky TW Jr, Portnoy DA, Stanley SA.

Cell Rep. 2018 May 1;23(5):1435-1447. doi: 10.1016/j.celrep.2018.04.003.


TNFα and Radioresistant Stromal Cells Are Essential for Therapeutic Efficacy of Cyclic Dinucleotide STING Agonists in Nonimmunogenic Tumors.

Francica BJ, Ghasemzadeh A, Desbien AL, Theodros D, Sivick KE, Reiner GL, Hix Glickman L, Marciscano AE, Sharabi AB, Leong ML, McWhirter SM, Dubensky TW Jr, Pardoll DM, Drake CG.

Cancer Immunol Res. 2018 Apr;6(4):422-433. doi: 10.1158/2326-6066.CIR-17-0263. Epub 2018 Feb 22.


Comorbidity Factors and Brain Mechanisms Linking Chronic Stress and Systemic Illness.

Duric V, Clayton S, Leong ML, Yuan LL.

Neural Plast. 2016;2016:5460732. doi: 10.1155/2016/5460732. Epub 2016 Feb 8. Review.


Effects of chronic constriction injury and spared nerve injury, two models of neuropathic pain, on the numbers of neurons and glia in the rostral ventromedial medulla.

Leong ML, Speltz R, Wessendorf M.

Neurosci Lett. 2016 Mar 23;617:82-7. doi: 10.1016/j.neulet.2016.02.006. Epub 2016 Feb 6.


Multiplexed Peptide-MHC Tetramer Staining with Mass Cytometry.

Leong ML, Newell EW.

Methods Mol Biol. 2015;1346:115-31. doi: 10.1007/978-1-4939-2987-0_9.


Multiple Genetic Mutations Associated with Polymyxin Resistance in Acinetobacter baumannii.

Lim TP, Ong RT, Hon PY, Hawkey J, Holt KE, Koh TH, Leong ML, Teo JQ, Tan TY, Ng MM, Hsu LY.

Antimicrob Agents Chemother. 2015 Dec;59(12):7899-902. doi: 10.1128/AAC.01884-15. Epub 2015 Oct 5.


Rationale, progress and development of vaccines utilizing STING-activating cyclic dinucleotide adjuvants.

Dubensky TW Jr, Kanne DB, Leong ML.

Ther Adv Vaccines. 2013 Nov;1(4):131-43. doi: 10.1177/2051013613501988. Review.


Draft Genome Sequence of Mycobacterium massiliense Strain M159, Showing Phenotypic Resistance to β-Lactam and Tetracycline Antibiotics.

Ngeow YF, Leong ML, Wong YL, Wong GJ, Tan JL, Wee WY, Ong CS, Pang YK, Choo SW.

Genome Announc. 2013 Aug 29;1(4). pii: e00669-13. doi: 10.1128/genomeA.00669-13.


Whole-Genome Shotgun Sequencing of Mycobacterium abscessus M156, an Emerging Clinical Pathogen in Malaysia.

Choo SW, Wong YL, Beh CY, Lokanathan N, Leong ML, Ong CS, Ng KP, Ngeow YF.

Genome Announc. 2013 Jan;1(1). pii: e00063-12. doi: 10.1128/genomeA.00063-12. Epub 2013 Jan 15.


Analysis of the genome of Mycobacterium abscessus strain M94 reveals an uncommon cluster of tRNAs.

Choo SW, Wong YL, Leong ML, Heydari H, Ong CS, Ng KP, Ngeow YF.

J Bacteriol. 2012 Oct;194(20):5724.


Genome sequence of the Mycobacterium abscessus strain M93.

Choo SW, Wong YL, Yusoff AM, Leong ML, Wong GJ, Ong CS, Ng KP, Ngeow YF.

J Bacteriol. 2012 Jun;194(12):3278. doi: 10.1128/JB.00492-12.


Neuronal loss in the rostral ventromedial medulla in a rat model of neuropathic pain.

Leong ML, Gu M, Speltz-Paiz R, Stahura EI, Mottey N, Steer CJ, Wessendorf M.

J Neurosci. 2011 Nov 23;31(47):17028-39. doi: 10.1523/JNEUROSCI.1268-11.2011.


Impact of preexisting vector-specific immunity on vaccine potency: characterization of listeria monocytogenes-specific humoral and cellular immunity in humans and modeling studies using recombinant vaccines in mice.

Leong ML, Hampl J, Liu W, Mathur S, Bahjat KS, Luckett W, Dubensky TW Jr, Brockstedt DG.

Infect Immun. 2009 Sep;77(9):3958-68. doi: 10.1128/IAI.01274-08. Epub 2009 Jun 15.


Importance of mitochondria in survival of Cryptococcus neoformans under low oxygen conditions and tolerance to cobalt chloride.

Ingavale SS, Chang YC, Lee H, McClelland CM, Leong ML, Kwon-Chung KJ.

PLoS Pathog. 2008 Sep 19;4(9):e1000155. doi: 10.1371/journal.ppat.1000155.


Constitutive Activation of the PrfA regulon enhances the potency of vaccines based on live-attenuated and killed but metabolically active Listeria monocytogenes strains.

Lauer P, Hanson B, Lemmens EE, Liu W, Luckett WS, Leong ML, Allen HE, Skoble J, Bahjat KS, Freitag NE, Brockstedt DG, Dubensky TW Jr.

Infect Immun. 2008 Aug;76(8):3742-53. doi: 10.1128/IAI.00390-08. Epub 2008 Jun 9.


Activation of immature hepatic NK cells as immunotherapy for liver metastatic disease.

Bahjat KS, Prell RA, Allen HE, Liu W, Lemmens EE, Leong ML, Portnoy DA, Dubensky TW Jr, Brockstedt DG, Giedlin MA.

J Immunol. 2007 Dec 1;179(11):7376-84.


Selective targeting of antitumor immune responses with engineered live-attenuated Listeria monocytogenes.

Yoshimura K, Jain A, Allen HE, Laird LS, Chia CY, Ravi S, Brockstedt DG, Giedlin MA, Bahjat KS, Leong ML, Slansky JE, Cook DN, Dubensky TW, Pardoll DM, Schulick RD.

Cancer Res. 2006 Jan 15;66(2):1096-104.


Topographic changes in SARS coronavirus-infected cells at late stages of infection.

Ng ML, Lee JW, Leong ML, Ling AE, Tan HC, Ooi EE.

Emerg Infect Dis. 2004 Nov;10(11):1907-14.


Listeria-based cancer vaccines that segregate immunogenicity from toxicity.

Brockstedt DG, Giedlin MA, Leong ML, Bahjat KS, Gao Y, Luckett W, Liu W, Cook DN, Portnoy DA, Dubensky TW Jr.

Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13832-7. Epub 2004 Sep 13.


Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway.

Park J, Leong ML, Buse P, Maiyar AC, Firestone GL, Hemmings BA.

EMBO J. 1999 Jun 1;18(11):3024-33.


'HIV transmission via blood and saliva splashes to the face'.

Leong ML.

Br Dent J. 1992 Feb 8;172(3):87. No abstract available.


Allergic reactions to cold sterilising solutions.

Leong ML.

Br Dent J. 1989 Oct 21;167(8):265. No abstract available.


'AIDS and dentistry'.

Leong ML.

Br Dent J. 1989 Sep 23;167(6):186. No abstract available.


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