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Items: 30


CD56bright NK cells exhibit potent antitumor responses following IL-15 priming.

Wagner JA, Rosario M, Romee R, Berrien-Elliott MM, Schneider SE, Leong JW, Sullivan RP, Jewell BA, Becker-Hapak M, Schappe T, Abdel-Latif S, Ireland AR, Jaishankar D, King JA, Vij R, Clement D, Goodridge J, Malmberg KJ, Wong HC, Fehniger TA.

J Clin Invest. 2017 Nov 1;127(11):4042-4058. doi: 10.1172/JCI90387. Epub 2017 Oct 3.


In Silico Prediction and Validation of Gfap as an miR-3099 Target in Mouse Brain.

Abidin SZ, Leong JW, Mahmoudi M, Nordin N, Abdullah S, Cheah PS, Ling KH.

Neurosci Bull. 2017 Aug;33(4):373-382. doi: 10.1007/s12264-017-0143-0. Epub 2017 Jun 8.


Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation.

Ho D, Leong JW, Crew RC, Norret M, House MJ, Mark PJ, Waddell BJ, Iyer KS, Keelan JA.

Sci Rep. 2017 Jun 6;7(1):2866. doi: 10.1038/s41598-017-03128-7.


Cytokine-Induced Memory-Like Differentiation Enhances Unlicensed Natural Killer Cell Antileukemia and FcγRIIIa-Triggered Responses.

Wagner JA, Berrien-Elliott MM, Rosario M, Leong JW, Jewell BA, Schappe T, Abdel-Latif S, Fehniger TA.

Biol Blood Marrow Transplant. 2017 Mar;23(3):398-404. doi: 10.1016/j.bbmt.2016.11.018. Epub 2016 Nov 25.


Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia.

Romee R, Rosario M, Berrien-Elliott MM, Wagner JA, Jewell BA, Schappe T, Leong JW, Abdel-Latif S, Schneider SE, Willey S, Neal CC, Yu L, Oh ST, Lee YS, Mulder A, Claas F, Cooper MA, Fehniger TA.

Sci Transl Med. 2016 Sep 21;8(357):357ra123. doi: 10.1126/scitranslmed.aaf2341.


Spatiotemporal Expression and Molecular Characterization of miR-344b and miR-344c in the Developing Mouse Brain.

Leong JW, Abdullah S, Ling KH, Cheah PS.

Neural Plast. 2016;2016:1951250. doi: 10.1155/2016/1951250. Epub 2016 Mar 1.


In depth analysis of the Sox4 gene locus that consists of sense and natural antisense transcripts.

Ling KH, Brautigan PJ, Moore S, Fraser R, Leong MP, Leong JW, Zainal Abidin S, Lee HC, Cheah PS, Raison JM, Babic M, Lee YK, Daish T, Mattiske DM, Mann JR, Adelson DL, Thomas PQ, Hahn CN, Scott HS.

Data Brief. 2016 Feb 17;7:282-90. doi: 10.1016/j.dib.2016.01.045. eCollection 2016 Jun.


Transcriptional and post-transcriptional regulation of NK cell development and function.

Leong JW, Wagner JA, Ireland AR, Fehniger TA.

Clin Immunol. 2017 Apr;177:60-69. doi: 10.1016/j.clim.2016.03.003. Epub 2016 Mar 3. Review.


The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas.

Rosario M, Liu B, Kong L, Collins LI, Schneider SE, Chen X, Han K, Jeng EK, Rhode PR, Leong JW, Schappe T, Jewell BA, Keppel CR, Shah K, Hess B, Romee R, Piwnica-Worms DR, Cashen AF, Bartlett NL, Wong HC, Fehniger TA.

Clin Cancer Res. 2016 Feb 1;22(3):596-608. doi: 10.1158/1078-0432.CCR-15-1419. Epub 2015 Sep 30.


MicroRNA-15/16 Antagonizes Myb To Control NK Cell Maturation.

Sullivan RP, Leong JW, Schneider SE, Ireland AR, Berrien-Elliott MM, Singh A, Schappe T, Jewell BA, Sexl V, Fehniger TA.

J Immunol. 2015 Sep 15;195(6):2806-17. doi: 10.4049/jimmunol.1500949. Epub 2015 Aug 12.


Therapeutic and safety considerations of nanoparticle-mediated drug delivery in pregnancy.

Keelan JA, Leong JW, Ho D, Iyer KS.

Nanomedicine (Lond). 2015 Jul;10(14):2229-47. doi: 10.2217/nnm.15.48. Review.


PTEN regulates natural killer cell trafficking in vivo.

Leong JW, Schneider SE, Sullivan RP, Parikh BA, Anthony BA, Singh A, Jewell BA, Schappe T, Wagner JA, Link DC, Yokoyama WM, Fehniger TA.

Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E700-9. doi: 10.1073/pnas.1413886112. Epub 2015 Feb 2.


microRNA management of NK-cell developmental and functional programs.

Leong JW, Sullivan RP, Fehniger TA.

Eur J Immunol. 2014 Oct;44(10):2862-8. doi: 10.1002/eji.201444798. Epub 2014 Sep 16. Review.


Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer.

Romee R, Leong JW, Fehniger TA.

Scientifica (Cairo). 2014;2014:205796. doi: 10.1155/2014/205796. Epub 2014 Jun 25. Review.


Changing molecular epidemiology and high rates of mupirocin resistance among meticillin-resistant Staphylococcus aureus in Singaporean hospitals.

Hon PY, Koh TH, Tan TY, Krishnan P, Leong JW, Jureen R, Chan J, Tee NW, Murugesh J, Chan KS, Hsu LY.

J Glob Antimicrob Resist. 2014 Mar;2(1):53-55. doi: 10.1016/j.jgar.2013.10.002. Epub 2013 Oct 31.


Preactivation with IL-12, IL-15, and IL-18 induces CD25 and a functional high-affinity IL-2 receptor on human cytokine-induced memory-like natural killer cells.

Leong JW, Chase JM, Romee R, Schneider SE, Sullivan RP, Cooper MA, Fehniger TA.

Biol Blood Marrow Transplant. 2014 Apr;20(4):463-73. doi: 10.1016/j.bbmt.2014.01.006. Epub 2014 Jan 13.


MicroRNA-155 tunes both the threshold and extent of NK cell activation via targeting of multiple signaling pathways.

Sullivan RP, Fogel LA, Leong JW, Schneider SE, Wong R, Romee R, Thai TH, Sexl V, Matkovich SJ, Dorn GW 2nd, French AR, Fehniger TA.

J Immunol. 2013 Dec 15;191(12):5904-13. doi: 10.4049/jimmunol.1301950. Epub 2013 Nov 13.


MicroRNA regulation of natural killer cells.

Sullivan RP, Leong JW, Fehniger TA.

Front Immunol. 2013 Feb 28;4:44. doi: 10.3389/fimmu.2013.00044. eCollection 2013.


Natural killer cell regulation by microRNAs in health and disease.

Leong JW, Sullivan RP, Fehniger TA.

J Biomed Biotechnol. 2012;2012:632329. doi: 10.1155/2012/632329. Epub 2012 Nov 19. Review.


Cytokine activation induces human memory-like NK cells.

Romee R, Schneider SE, Leong JW, Chase JM, Keppel CR, Sullivan RP, Cooper MA, Fehniger TA.

Blood. 2012 Dec 6;120(24):4751-60. doi: 10.1182/blood-2012-04-419283. Epub 2012 Sep 14.


Management of the American Heart Association's guidelines for orthodontic treatment of patients at risk for infective endocarditis.

Leong JW, Kunzel C, Cangialosi TJ.

Am J Orthod Dentofacial Orthop. 2012 Sep;142(3):348-54. doi: 10.1016/j.ajodo.2012.05.002.


Impairments to the GH-IGF-I axis in hSOD1G93A mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis.

Steyn FJ, Ngo ST, Lee JD, Leong JW, Buckley AJ, Veldhuis JD, McCombe PA, Chen C, Bellingham MC.

Endocrinology. 2012 Aug;153(8):3735-46. doi: 10.1210/en.2011-2171. Epub 2012 May 23.


MicroRNA-deficient NK cells exhibit decreased survival but enhanced function.

Sullivan RP, Leong JW, Schneider SE, Keppel CR, Germino E, French AR, Fehniger TA.

J Immunol. 2012 Apr 1;188(7):3019-30. doi: 10.4049/jimmunol.1102294. Epub 2012 Feb 29.


GH does not modulate the early fasting-induced release of free fatty acids in mice.

Steyn FJ, Leong JW, Huang L, Tan HY, Xie TY, Nelson C, Waters MJ, Veldhuis JD, Epelbaum J, Chen C.

Endocrinology. 2012 Jan;153(1):273-82. doi: 10.1210/en.2011-1681. Epub 2011 Nov 22.


Development of a method for the determination of pulsatile growth hormone secretion in mice.

Steyn FJ, Huang L, Ngo ST, Leong JW, Tan HY, Xie TY, Parlow AF, Veldhuis JD, Waters MJ, Chen C.

Endocrinology. 2011 Aug;152(8):3165-71. doi: 10.1210/en.2011-0253. Epub 2011 May 17.


Human NK cells: SET to kill.

Leong JW, Fehniger TA.

Blood. 2011 Feb 24;117(8):2297-8. doi: 10.1182/blood-2011-01-327247.


Next-generation sequencing identifies the natural killer cell microRNA transcriptome.

Fehniger TA, Wylie T, Germino E, Leong JW, Magrini VJ, Koul S, Keppel CR, Schneider SE, Koboldt DC, Sullivan RP, Heinz ME, Crosby SD, Nagarajan R, Ramsingh G, Link DC, Ley TJ, Mardis ER.

Genome Res. 2010 Nov;20(11):1590-604. doi: 10.1101/gr.107995.110. Epub 2010 Oct 8.


In vivo role of Flt3 ligand and dendritic cells in NK cell homeostasis.

Guimond M, Freud AG, Mao HC, Yu J, Blaser BW, Leong JW, Vandeusen JB, Dorrance A, Zhang J, Mackall CL, Caligiuri MA.

J Immunol. 2010 Mar 15;184(6):2769-75. doi: 10.4049/jimmunol.0900685. Epub 2010 Feb 8.


Early hepatocellular carcinoma presenting with biliary ductal invasion--a case report.

Leong JW, Ho JM, Ng HS, Raj JP.

Ann Acad Med Singapore. 2000 Jan;29(1):101-4.


The elimination half-life of urinary cotinine in children of tobacco-smoking mothers.

Leong JW, Dore ND, Shelley K, Holt EJ, Laing IA, Palmer LJ, LeSouef PN.

Pulm Pharmacol Ther. 1998;11(4):287-90.


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