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Items: 1 to 50 of 55

1.

Post-transcriptional Regulation of Colorectal Cancer: A Focus on RNA-Binding Proteins.

García-Cárdenas JM, Guerrero S, López-Cortés A, Armendáriz-Castillo I, Guevara-Ramírez P, Pérez-Villa A, Yumiceba V, Zambrano AK, Leone PE, Paz-Y-Miño C.

Front Mol Biosci. 2019 Aug 7;6:65. doi: 10.3389/fmolb.2019.00065. eCollection 2019. Review.

2.

The three-hybrid genetic composition of an Ecuadorian population using AIMs-InDels compared with autosomes, mitochondrial DNA and Y chromosome data.

Zambrano AK, Gaviria A, Cobos-Navarrete S, Gruezo C, Rodríguez-Pollit C, Armendáriz-Castillo I, García-Cárdenas JM, Guerrero S, López-Cortés A, Leone PE, Pérez-Villa A, Guevara-Ramírez P, Yumiceba V, Fiallos G, Vela M, Paz-Y-Miño C.

Sci Rep. 2019 Jun 25;9(1):9247. doi: 10.1038/s41598-019-45723-w.

3.

A quick guide for using Microsoft OneNote as an electronic laboratory notebook.

Guerrero S, López-Cortés A, García-Cárdenas JM, Saa P, Indacochea A, Armendáriz-Castillo I, Zambrano AK, Yumiceba V, Pérez-Villa A, Guevara-Ramírez P, Moscoso-Zea O, Paredes J, Leone PE, Paz-Y-Miño C.

PLoS Comput Biol. 2019 May 9;15(5):e1006918. doi: 10.1371/journal.pcbi.1006918. eCollection 2019 May.

4.

Salivary MicroRNAs for Early Detection of Head and Neck Squamous Cell Carcinoma: A Case-Control Study in the High Altitude Mestizo Ecuadorian Population.

Salazar-Ruales C, Arguello JV, López-Cortés A, Cabrera-Andrade A, García-Cárdenas JM, Guevara-Ramírez P, Peralta P, Leone PE, Paz-Y-Miño C.

Biomed Res Int. 2018 Nov 21;2018:9792730. doi: 10.1155/2018/9792730. eCollection 2018.

5.

Ring chromosome 15 - cytogenetics and mapping arrays: a case report and review of the literature.

Paz-Y-Miño C, Guevara-Aguirre J, Paz-Y-Miño A, Velarde F, Armendáriz-Castillo I, Yumiceba V, Hernández JM, García JL, Leone PE.

J Med Case Rep. 2018 Nov 16;12(1):340. doi: 10.1186/s13256-018-1879-5. Review.

6.

Analysis of Racial/Ethnic Representation in Select Basic and Applied Cancer Research Studies.

Guerrero S, López-Cortés A, Indacochea A, García-Cárdenas JM, Zambrano AK, Cabrera-Andrade A, Guevara-Ramírez P, González DA, Leone PE, Paz-Y-Miño C.

Sci Rep. 2018 Sep 18;8(1):13978. doi: 10.1038/s41598-018-32264-x.

7.

Mutational Analysis of Oncogenic AKT1 Gene Associated with Breast Cancer Risk in the High Altitude Ecuadorian Mestizo Population.

López-Cortés A, Leone PE, Freire-Paspuel B, Arcos-Villacís N, Guevara-Ramírez P, Rosales F, Paz-Y-Miño C.

Biomed Res Int. 2018 Jul 3;2018:7463832. doi: 10.1155/2018/7463832. eCollection 2018.

8.

Genotyping the High Altitude Mestizo Ecuadorian Population Affected with Prostate Cancer.

López-Cortés A, Cabrera-Andrade A, Salazar-Ruales C, Zambrano AK, Guerrero S, Guevara P, Leone PE, Paz-Y-Miño C.

Biomed Res Int. 2017;2017:3507671. doi: 10.1155/2017/3507671. Epub 2017 Jun 8. Review.

9.

Study of the Huntington's disease IT-15 gene in different ethnic groups in Ecuador.

Paz-Y-Miño C, Salazar-Ruales C, García-Cárdenas JM, Cabrera-Andrade A, López-Cortés A, Pavón-Realpe VH, Eras E, Rodriguez P C, Domínguez Enríquez JP, Cusco Cuzco CD, Navarrete Socasi DC, Leone PE.

Clin Genet. 2017 Nov;92(5):544-547. doi: 10.1111/cge.13028. Epub 2017 Aug 17.

PMID:
28369732
10.

Positive association of the androgen receptor CAG repeat length polymorphism with the risk of prostate cancer.

Paz-Y-Miño C, Robles P, Salazar C, Leone PE, García-Cárdenas JM, Naranjo M, López-Cortés A.

Mol Med Rep. 2016 Aug;14(2):1791-8. doi: 10.3892/mmr.2016.5414. Epub 2016 Jun 21.

PMID:
27357524
11.

Genetics and genomic medicine in Ecuador.

Paz-Y-Miño C, Guillen Sacoto MJ, Leone PE.

Mol Genet Genomic Med. 2015 Dec 21;4(1):9-17. doi: 10.1002/mgg3.192. eCollection 2016 Jan. No abstract available.

12.

Positive Association of the Cathepsin D Ala224Val Gene Polymorphism With the Risk of Alzheimer's Disease.

Paz-Y-Miño CA, García-Cárdenas JM, López-Cortés A, Salazar C, Serrano M, Leone PE.

Am J Med Sci. 2015 Oct;350(4):296-301. doi: 10.1097/MAJ.0000000000000555.

PMID:
26351775
13.

Association of genetic variants of membrane receptors related to recognition and induction of immune response with Helicobacter pylori infection in Ecuadorian individuals.

Cabrera-Andrade A, López-Cortés A, Muñoz MJ, Jaramillo-Koupermann G, Rodriguez O, Leone PE, Paz-y-Miño C.

Int J Immunogenet. 2014 Aug;41(4):281-8. doi: 10.1111/iji.12118. Epub 2014 Apr 23.

PMID:
24754375
14.

Expression profile of telomere-associated genes in multiple myeloma.

Díaz de la Guardia R, Catalina P, Panero J, Elosua C, Pulgarin A, López MB, Ayllón V, Ligero G, Slavutsky I, Leone PE.

J Cell Mol Med. 2012 Dec;16(12):3009-21. doi: 10.1111/j.1582-4934.2012.01628.x.

15.

Integration of global spectral karyotyping, CGH arrays, and expression arrays reveals important genes in the pathogenesis of glioblastoma multiforme.

Leone PE, González MB, Elosua C, Gómez-Moreta JA, Lumbreras E, Robledo C, Santos-Briz A, Valero JM, de la Guardia RD, Gutiérrez NC, Hernández JM, García JL.

Ann Surg Oncol. 2012 Jul;19(7):2367-79. doi: 10.1245/s10434-011-2202-5. Epub 2012 Mar 7.

PMID:
22395973
16.

High-resolution genomic profiling in hairy cell leukemia-variant compared with typical hairy cell leukemia.

Hockley SL, Morgan GJ, Leone PE, Walker BA, Morilla A, Else M, Wotherspoon A, Dearden C, Catovsky D, Gonzalez D, Matutes E.

Leukemia. 2011 Jul;25(7):1189-92. doi: 10.1038/leu.2011.47. Epub 2011 Mar 25. No abstract available.

PMID:
21436839
17.

A compendium of myeloma-associated chromosomal copy number abnormalities and their prognostic value.

Walker BA, Leone PE, Chiecchio L, Dickens NJ, Jenner MW, Boyd KD, Johnson DC, Gonzalez D, Dagrada GP, Protheroe RK, Konn ZJ, Stockley DM, Gregory WM, Davies FE, Ross FM, Morgan GJ.

Blood. 2010 Oct 14;116(15):e56-65. doi: 10.1182/blood-2010-04-279596. Epub 2010 Jul 8.

18.

Deficiency in p53 but not retinoblastoma induces the transformation of mesenchymal stem cells in vitro and initiates leiomyosarcoma in vivo.

Rubio R, García-Castro J, Gutiérrez-Aranda I, Paramio J, Santos M, Catalina P, Leone PE, Menendez P, Rodríguez R.

Cancer Res. 2010 May 15;70(10):4185-94. doi: 10.1158/0008-5472.CAN-09-4640. Epub 2010 May 4.

19.

Homozygous deletion mapping in myeloma samples identifies genes and an expression signature relevant to pathogenesis and outcome.

Dickens NJ, Walker BA, Leone PE, Johnson DC, Brito JL, Zeisig A, Jenner MW, Boyd KD, Gonzalez D, Gregory WM, Ross FM, Davies FE, Morgan GJ.

Clin Cancer Res. 2010 Mar 15;16(6):1856-64. doi: 10.1158/1078-0432.CCR-09-2831. Epub 2010 Mar 9.

20.

Mesenchymal stem cells facilitate the derivation of human embryonic stem cells from cryopreserved poor-quality embryos.

Cortes JL, Sanchez L, Ligero G, Gutierrez-Aranda I, Catalina P, Elosua C, Leone PE, Montes R, Bueno C, Ramos-Mejía V, Maleno I, García-Pérez JL, Menendez P.

Hum Reprod. 2009 Aug;24(8):1844-51. doi: 10.1093/humrep/dep107. Epub 2009 Apr 28.

PMID:
19401322
21.

Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties?

Catalina P, Montes R, Ligero G, Sanchez L, de la Cueva T, Bueno C, Leone PE, Menendez P.

Mol Cancer. 2008 Oct 3;7:76. doi: 10.1186/1476-4598-7-76.

22.

Deletions of CDKN2C in multiple myeloma: biological and clinical implications.

Leone PE, Walker BA, Jenner MW, Chiecchio L, Dagrada G, Protheroe RK, Johnson DC, Dickens NJ, Brito JL, Else M, Gonzalez D, Ross FM, Chen-Kiang S, Davies FE, Morgan GJ.

Clin Cancer Res. 2008 Oct 1;14(19):6033-41. doi: 10.1158/1078-0432.CCR-08-0347.

23.

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma.

Jenner MW, Leone PE, Walker BA, Ross FM, Johnson DC, Gonzalez D, Chiecchio L, Dachs Cabanas E, Dagrada GP, Nightingale M, Protheroe RK, Stockley D, Else M, Dickens NJ, Cross NC, Davies FE, Morgan GJ.

Blood. 2007 Nov 1;110(9):3291-300. Epub 2007 Jul 3.

24.

Follow-up study of patients diagnosed with chronic myelogenous leukemia treated with STI 571 in Ecuador.

Paz-Y-Miño C, Arévalo M, Sánchez ME, Cañizares C, Leone PE.

Arch Med Res. 2007 Apr;38(3):364-5. Epub 2007 Jan 30. No abstract available.

PMID:
17350491
25.

Genetics and congenital malformations: interpretations, attitudes and practices in suburban communities and the shamans of ecuador.

Paz-Y-Miño C, Sánchez ME, Sarmiento I, Leone PE.

Community Genet. 2006;9(4):268-73.

PMID:
17003537
26.

Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma.

Walker BA, Leone PE, Jenner MW, Li C, Gonzalez D, Johnson DC, Ross FM, Davies FE, Morgan GJ.

Blood. 2006 Sep 1;108(5):1733-43. Epub 2006 May 16.

27.

CCR5delta32, CCR2-64I, and SDF1-3'A polymorphisms related to resistance to HIV-1 infection and disease in the Ecuadorian population.

Paz-y-Mino C, Morillo SA, Celi AP, Witte T, Muñoz Guijarro MJ, Collantes JC, Leone PE.

Hum Biol. 2005 Aug;77(4):521-6.

PMID:
16485782
28.

CYP1A1 genetic polymorphisms in Ecuador, South America.

Paz-y-Miño C, Arévalo M, Muñoz G MJ, Leone PE.

Dis Markers. 2005;21(2):57-9.

29.

Chromosomal abnormalities are related to location and grade of osteoarthritis.

Castellanos MV, Hernández JM, Ramos L, Belén González M, Gutiérrez NC, Leone PE, Lumbreras E, Robledo C, García Hernández JL.

Osteoarthritis Cartilage. 2004 Dec;12(12):982-5.

30.

Analysis of HFE gene mutations (C282Y, H63D, and S65C) in the Ecuadorian population.

Leone PE, Giménez P, Collantes JC, Paz-y-Miño C.

Ann Hematol. 2005 Feb;84(2):103-5. Epub 2004 Oct 29.

PMID:
15517265
31.
32.

Two new mutations and three novel polymorphisms in the RB1 gene in Ecuadorian patients.

Leone PE, Vega ME, Jervis P, Pestaña A, Alonso J, Paz-y-Miño C.

J Hum Genet. 2003;48(12):639-41. Epub 2003 Nov 19.

PMID:
14625809
33.

B3/A3 rearrangement in a patient with chronic myeloid leukemia.

Paz-Y-Miño C, Arévalo M, Leone PE.

Leuk Lymphoma. 2003 Feb;44(2):375-6.

PMID:
12688363
34.

Analysis of the polymorphism [gIVS12-6T > C] in the hMSH2 gene in lymphoma and leukemia.

Paz-y-Miño C, Fiallo BF, Morillo SA, Acosta A, Giménez P, Ocampo L, Leone PE.

Leuk Lymphoma. 2003 Mar;44(3):505-8.

PMID:
12688322
35.

Implications of a RAD54L polymorphism (2290C/T) in human meningiomas as a risk factor and/or a genetic marker.

Leone PE, Mendiola M, Alonso J, Paz-y-Miño C, Pestaña A.

BMC Cancer. 2003 Mar 4;3:6. Epub 2003 Mar 4.

36.

Cytogenetic monitoring in a population occupationally exposed to pesticides in Ecuador.

Paz-y-Miño C, Bustamante G, Sánchez ME, Leone PE.

Environ Health Perspect. 2002 Nov;110(11):1077-80.

37.

Low incidence of follicular lymphoma and t(14;18)(q32;q21) by polymerase chain reaction analysis. observations on Ecuadorian patients.

Leone PE, Pérez JC, Morillo SA, Paz-y-Miño C.

Cancer Genet Cytogenet. 2002 Aug;137(1):72-4.

PMID:
12377418
38.

Alternative strategies for school violence prevention.

Gagnon JC, Leone PE.

New Dir Youth Dev. 2001 Winter;92:101-25. Review.

PMID:
12170826
39.

Should gaps be included in chromosomal aberration analysis? Evidence based on the comet assay.

Paz-y-Miño C, Dávalos MV, Sánchez ME, Arévalo M, Leone PE.

Mutat Res. 2002 Apr 26;516(1-2):57-61.

PMID:
11943611
40.

A polymorphism in the hMSH2 gene (gIVS12-6T>C) associated with non-Hodgkin lymphomas.

Paz-y-Miño C, Pérez JC, Fiallo BF, Leone PE.

Cancer Genet Cytogenet. 2002 Feb;133(1):29-33.

PMID:
11890986
41.

BCR-ABL rearrangement frequencies in chronic myeloid leukemia and acute lymphoblastic leukemia in Ecuador, South America.

Paz-y-Miño C, Burgos R, Morillo SA, Santos JC, Fiallo BF, Leone PE.

Cancer Genet Cytogenet. 2002 Jan 1;132(1):65-7.

PMID:
11801312
42.

Telomeric associations in cigarette smokers exposed to low levels of X-rays.

Paz-y-Miño C, Pérez JC, Dávalos V, Sánchez ME, Leone PE.

Mutat Res. 2001 Jan 25;490(1):77-80.

PMID:
11152974
43.

Three novel somatic mutations in the NF2 tumor suppressor gene [g816T>A; g1159A>G; gIVS11-1G>T].

Paz-y-Miño C, Leone PE.

Hum Mutat. 2000 May;15(5):487. No abstract available.

PMID:
10790227
44.

The DeltaF508 mutation in Ecuador, South America.

Paz-y-Miño C, Pérez JC, Burgos R, Dávalos MV, Leone PE.

Hum Mutat. 1999;14(4):348-50.

PMID:
10502783
45.

Adolescent substance use: preliminary examinations of school and neighborhood context.

Allison KW, Crawford I, Leone PE, Trickett E, Perez-Febles A, Burton LM, Le Blanc R.

Am J Community Psychol. 1999 Apr;27(2):111-41.

PMID:
10425696
46.

NF2 gene mutations and allelic status of 1p, 14q and 22q in sporadic meningiomas.

Leone PE, Bello MJ, de Campos JM, Vaquero J, Sarasa JL, Pestaña A, Rey JA.

Oncogene. 1999 Apr 1;18(13):2231-9.

47.

Search for mutations of the hRAD54 gene in sporadic meningiomas with deletion at 1p32.

Mendiola M, Bello MJ, Alonso J, Leone PE, Vaquero J, Sarasa JL, Kusak ME, De Campos JM, Pestaña A, Rey JA.

Mol Carcinog. 1999 Apr;24(4):300-4.

PMID:
10326867
48.

Allelic status of 1p, 14q, and 22q and NF2 gene mutations in sporadic schwannomas.

Leone PE, Bello MJ, Mendiola M, Kusak ME, De Campos JM, Vaquero J, Sarasa JL, Pestana A, Rey JA.

Int J Mol Med. 1998 May;1(5):889-92.

PMID:
9852312
49.

Six novel mutations in the NF2 tumor suppressor gene.

Leone PE, Bello MJ, Mendiola M, Vaquero J, Sarasa JL, Kusak ME, De Campos JM, Pestana A, Rey JA.

Int J Oncol. 1998 Apr;12(4):935-8.

PMID:
9499458
50.

Telomeric association in women with breast and uterine cervix cancer.

Paz-y-Miño C, Sánchez ME, Del Pozo M, Baldeón MA, Córdova A, Gutiérrez S, Peñaherrera MS, Neira M, Ocampo L, Leone PE.

Cancer Genet Cytogenet. 1997 Oct 15;98(2):115-8.

PMID:
9332475

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