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ID30B - a versatile beamline for macromolecular crystallography experiments at the ESRF.

McCarthy AA, Barrett R, Beteva A, Caserotto H, Dobias F, Felisaz F, Giraud T, Guijarro M, Janocha R, Khadrouche A, Lentini M, Leonard GA, Lopez Marrero M, Malbet-Monaco S, McSweeney S, Nurizzo D, Papp G, Rossi C, Sinoir J, Sorez C, Surr J, Svensson O, Zander U, Cipriani F, Theveneau P, Mueller-Dieckmann C.

J Synchrotron Radiat. 2018 Jul 1;25(Pt 4):1249-1260. doi: 10.1107/S1600577518007166. Epub 2018 Jun 27.


Association of Motoric Cognitive Risk Syndrome with Cardiovascular Disease and Risk Factors: Results from an Original Study and Meta-Analysis.

Beauchet O, Sekhon H, Barden J, Liu-Ambrose T, Chester VL, Szturm T, Grenier S, Léonard G, Bherer L, Allali G; Canadian Gait Consortium.

J Alzheimers Dis. 2018;64(3):875-887. doi: 10.3233/JAD-180203.


The Ottawa Panel guidelines on programmes involving therapeutic exercise for the management of hand osteoarthritis.

Brosseau L, Thevenot O, MacKiddie O, Taki J, Wells GA, Guitard P, Léonard G, Paquet N, Aydin SZ, Toupin-April K, Cavallo S, Moe RH, Shaikh K, Gifford W, Loew L, De Angelis G, Shallwani SM, Aburub AS, Mizusaki Imoto A, Rahman P, Álvarez Gallardo IC, Cosic MB, Østerås N, Lue S, Hamasaki T, Gaudreault N, Towheed TE, Koppikar S, Kjeken I, Mahendira D, Kenny GP, Paterson G, Westby M, Laferrière L, Longchamp G.

Clin Rehabil. 2018 Jun 1:269215518780973. doi: 10.1177/0269215518780973. [Epub ahead of print]


Multicenter, randomized, double-blind phase 2 trial of FOLFIRI with regorafenib or placebo as second-line therapy for metastatic colorectal cancer.

Sanoff HK, Goldberg RM, Ivanova A, O'Reilly S, Kasbari SS, Kim RD, McDermott R, Moore DT, Zamboni W, Grogan W, Cohn AL, Bekaii-Saab TS, Leonard G, Ryan T, Olowokure OO, Fernando NH, McCaffrey J, El-Rayes BF, Horgan AM, Sherrill GB, Yacoub GH, O'Neil BH.

Cancer. 2018 Jun 15. doi: 10.1002/cncr.31552. [Epub ahead of print]


A new MR-SAD algorithm for the automatic building of protein models from low-resolution X-ray data and a poor starting model.

Skubák P, Araç D, Bowler MW, Correia AR, Hoelz A, Larsen S, Leonard GA, McCarthy AA, McSweeney S, Mueller-Dieckmann C, Otten H, Salzman G, Pannu NS.

IUCrJ. 2018 Jan 25;5(Pt 2):166-171. doi: 10.1107/S2052252517017961. eCollection 2018 Mar 1.


Cognitive predictors of sequential motor impairments in children with dyslexia and/or attention deficit/hyperactivity disorder.

Marchand-Krynski MÈ, Bélanger AM, Morin-Moncet O, Beauchamp MH, Leonard G.

Dev Neuropsychol. 2018;43(5):430-453. doi: 10.1080/87565641.2018.1467421. Epub 2018 May 15.


Anodal Transcranial Direct-Current Stimulation to Enhance Rehabilitation in Individuals With Rotator Cuff Tendinopathy: A Triple-Blind Randomized Controlled Trial.

Belley AF, Mercier C, Bastien M, Léonard G, Gaudreault N, Roy JS.

J Orthop Sports Phys Ther. 2018 Jul;48(7):541-551. doi: 10.2519/jospt.2018.7871. Epub 2018 May 10.


The complex analysis of X-ray mesh scans for macromolecular crystallography.

Melnikov I, Svensson O, Bourenkov G, Leonard G, Popov A.

Acta Crystallogr D Struct Biol. 2018 Apr 1;74(Pt 4):355-365. doi: 10.1107/S2059798318002735. Epub 2018 Apr 6.


Cartilage Metabolism is Modulated by Synovial Fluid Through Metalloproteinase Activity.

Sun EY, Fleck AKM, Abu-Hakmeh AE, Kotsakis A, Leonard GR, Wan LQ.

Ann Biomed Eng. 2018 Jun;46(6):810-818. doi: 10.1007/s10439-018-2010-1. Epub 2018 Mar 27.


Place of surgery in the management of post-operative chronic pain after placement of prosthetic material based on a series of 107 cases.

Leonard G, Perrouin-Verbe MA, Levesque A, Riant T, Normand LL, Labat JJ, Rigaud J.

Neurourol Urodyn. 2018 Mar 23. doi: 10.1002/nau.23544. [Epub ahead of print]


Transcutaneous electrical nerve stimulation and placebo analgesia: is the effect the same for young and older individuals?

Daguet I, Bergeron-Vézina K, Harvey MP, Martel M, Léonard G.

Clin Interv Aging. 2018 Feb 28;13:335-342. doi: 10.2147/CIA.S152906. eCollection 2018.


The knitting community-based trial for older women with osteoarthritis of the hands: design and rationale of a randomized controlled trial.

Guitard P, Brosseau L, Wells GA, Paquet N, Paterson G, Toupin-April K, Cavallo S, Aydin SZ, Léonard G, De Angelis G.

BMC Musculoskelet Disord. 2018 Feb 14;19(1):56. doi: 10.1186/s12891-018-1965-2.


Comparative genomic analysis of the 'pseudofungus' Hyphochytrium catenoides.

Leonard G, Labarre A, Milner DS, Monier A, Soanes D, Wideman JG, Maguire F, Stevens S, Sain D, Grau-Bové X, Sebé-Pedrós A, Stajich JE, Paszkiewicz K, Brown MW, Hall N, Wickstead B, Richards TA.

Open Biol. 2018 Jan;8(1). pii: 170184. doi: 10.1098/rsob.170184.


Letter to the Editor: RE: Costa et al. (''Nutritional Risk is Associated with Chronic Musculoskeletal Pain in Community-Dwelling Older Persons: The PAINEL Study'').

Bagna M, Léonard G, Cohen A, Carrier JD, Payette H.

J Nutr Gerontol Geriatr. 2017 Oct-Dec;36(4):199-203. doi: 10.1080/21551197.2017.1401502.


Hierarchical clustering for multiple-crystal macromolecular crystallography experiments: the ccCluster program.

Santoni G, Zander U, Mueller-Dieckmann C, Leonard G, Popov A.

J Appl Crystallogr. 2017 Nov 29;50(Pt 6):1844-1851. doi: 10.1107/S1600576717015229. eCollection 2017 Dec 1.


Adjusting Pulse Amplitude During Transcutaneous Electrical Nerve Stimulation Does Not Provide Greater Hypoalgesia.

Bergeron-Vézina K, Filion C, Couture C, Vallée É, Laroche S, Léonard G.

J Altern Complement Med. 2018 Mar;24(3):262-267. doi: 10.1089/acm.2016.0184. Epub 2017 Nov 8.


Unpredictable pain timings lead to greater pain when people are highly intolerant of uncertainty.

Bélanger C, Blais Morin B, Brousseau A, Gagné N, Tremblay A, Daigle K, Goffaux P, Léonard G.

Scand J Pain. 2017 Oct;17:367-372. doi: 10.1016/j.sjpain.2017.09.013. Epub 2017 Oct 13.


Single cell genomics of uncultured marine alveolates shows paraphyly of basal dinoflagellates.

Strassert JFH, Karnkowska A, Hehenberger E, Del Campo J, Kolisko M, Okamoto N, Burki F, Janouškovec J, Poirier C, Leonard G, Hallam SJ, Richards TA, Worden AZ, Santoro AE, Keeling PJ.

ISME J. 2018 Jan;12(1):304-308. doi: 10.1038/ismej.2017.167. Epub 2017 Oct 10.


Cell-Specific Gene-Expression Profiles and Cortical Thickness in the Human Brain.

Shin J, French L, Xu T, Leonard G, Perron M, Pike GB, Richer L, Veillette S, Pausova Z, Paus T.

Cereb Cortex. 2017 Aug 9:1-11. doi: 10.1093/cercor/bhx197. [Epub ahead of print]


Can We Quickly and Thoroughly Assess Pain with the PACSLAC-II? A Convergent Validity Study in Long-Term Care Residents Suffering from Dementia.

Ruest M, Bourque M, Laroche S, Harvey MP, Martel M, Bergeron-Vézina K, Apinis C, Proulx D, Hadjistavropoulos T, Tousignant-Laflamme Y, Léonard G.

Pain Manag Nurs. 2017 Dec;18(6):410-417. doi: 10.1016/j.pmn.2017.05.009. Epub 2017 Aug 24.


Guidelines for Assessment of Gait and Reference Values for Spatiotemporal Gait Parameters in Older Adults: The Biomathics and Canadian Gait Consortiums Initiative.

Beauchet O, Allali G, Sekhon H, Verghese J, Guilain S, Steinmetz JP, Kressig RW, Barden JM, Szturm T, Launay CP, Grenier S, Bherer L, Liu-Ambrose T, Chester VL, Callisaya ML, Srikanth V, Léonard G, De Cock AM, Sawa R, Duque G, Camicioli R, Helbostad JL.

Front Hum Neurosci. 2017 Aug 3;11:353. doi: 10.3389/fnhum.2017.00353. eCollection 2017.


Income inequality, gene expression, and brain maturation during adolescence.

Parker N, Wong AP, Leonard G, Perron M, Pike B, Richer L, Veillette S, Pausova Z, Paus T.

Sci Rep. 2017 Aug 7;7(1):7397. doi: 10.1038/s41598-017-07735-2.


Dynamics of genomic innovation in the unicellular ancestry of animals.

Grau-Bové X, Torruella G, Donachie S, Suga H, Leonard G, Richards TA, Ruiz-Trillo I.

Elife. 2017 Jul 20;6. pii: e26036. doi: 10.7554/eLife.26036.


The Effectiveness of Transcranial Direct Current Stimulation as an Add-on Modality to Graded Motor Imagery for Treatment of Complex Regional Pain Syndrome: A Randomized Proof of Concept Study.

Lagueux É, Bernier M, Bourgault P, Whittingstall K, Mercier C, Léonard G, Laroche S, Tousignant-Laflamme Y.

Clin J Pain. 2018 Feb;34(2):145-154. doi: 10.1097/AJP.0000000000000522.


Can we improve pain and sleep in elderly individuals with transcranial direct current stimulation? - Results from a randomized controlled pilot study.

Harvey MP, Lorrain D, Martel M, Bergeron-Vezina K, Houde F, Séguin M, Léonard G.

Clin Interv Aging. 2017 Jun 6;12:937-947. doi: 10.2147/CIA.S133423. eCollection 2017.


What Defines the "Kingdom" Fungi?

Richards TA, Leonard G, Wideman JG.

Microbiol Spectr. 2017 Jun;5(3). doi: 10.1128/microbiolspec.FUNK-0044-2017. Review.


Non-invasive stimulation techniques to relieve abdominal/pelvic pain: Is more always better?

Harvey MP, Watier A, Dufort Rouleau É, Léonard G.

World J Gastroenterol. 2017 May 28;23(20):3758-3760. doi: 10.3748/wjg.v23.i20.3758.


Noninvasive tongue stimulation combined with intensive cognitive and physical rehabilitation induces neuroplastic changes in patients with multiple sclerosis: A multimodal neuroimaging study.

Leonard G, Lapierre Y, Chen JK, Wardini R, Crane J, Ptito A.

Mult Scler J Exp Transl Clin. 2017 Feb 1;3(1):2055217317690561. doi: 10.1177/2055217317690561. eCollection 2017 Jan-Mar.


ICORG 10-14: NEOadjuvant trial in Adenocarcinoma of the oEsophagus and oesophagoGastric junction International Study (Neo-AEGIS).

Reynolds JV, Preston SR, O'Neill B, Baeksgaard L, Griffin SM, Mariette C, Cuffe S, Cunningham M, Crosby T, Parker I, Hofland K, Hanna G, Svendsen LB, Donohoe CL, Muldoon C, O'Toole D, Johnson C, Ravi N, Jones G, Corkhill AK, Illsley M, Mellor J, Lee K, Dib M, Marchesin V, Cunnane M, Scott K, Lawner P, Warren S, O'Reilly S, O'Dowd G, Leonard G, Hennessy B, Dermott RM.

BMC Cancer. 2017 Jun 3;17(1):401. doi: 10.1186/s12885-017-3386-2.


A bicentric comparative and prospective study between classic photovaporization and anatomical GreenLight laser vaporization for large-volume prostatic adenomas.

Hibon G, Léonard G, Franceschi A, Misrai V, Bruyère F.

Prog Urol. 2017 Jun - Jul;27(8-9):482-488. doi: 10.1016/j.purol.2017.04.006. Epub 2017 May 31.


Shared and differentiated motor skill impairments in children with dyslexia and/or attention deficit disorder: From simple to complex sequential coordination.

Marchand-Krynski MÈ, Morin-Moncet O, Bélanger AM, Beauchamp MH, Leonard G.

PLoS One. 2017 May 19;12(5):e0177490. doi: 10.1371/journal.pone.0177490. eCollection 2017.


Mechanism of transmembrane signaling by sensor histidine kinases.

Gushchin I, Melnikov I, Polovinkin V, Ishchenko A, Yuzhakova A, Buslaev P, Bourenkov G, Grudinin S, Round E, Balandin T, Borshchevskiy V, Willbold D, Leonard G, Büldt G, Popov A, Gordeliy V.

Science. 2017 Jun 9;356(6342). pii: eaah6345. doi: 10.1126/science.aah6345. Epub 2017 May 18.


Fast iodide-SAD phasing for high-throughput membrane protein structure determination.

Melnikov I, Polovinkin V, Kovalev K, Gushchin I, Shevtsov M, Shevchenko V, Mishin A, Alekseev A, Rodriguez-Valera F, Borshchevskiy V, Cherezov V, Leonard GA, Gordeliy V, Popov A.

Sci Adv. 2017 May 12;3(5):e1602952. doi: 10.1126/sciadv.1602952. eCollection 2017 May.


Radial shockwave therapy for a painful bone spur in an above-knee amputee.

Demers-Dubuc S, Cabana F, Couture ÉL, Chalaye P, Léonard G.

Ann Phys Rehabil Med. 2017 Sep;60(5):357-359. doi: 10.1016/ Epub 2017 Apr 1. No abstract available.


Inter-Regional Variations in Gene Expression and Age-Related Cortical Thinning in the Adolescent Brain.

Wong AP, French L, Leonard G, Perron M, Pike GB, Richer L, Veillette S, Pausova Z, Paus T.

Cereb Cortex. 2018 Apr 1;28(4):1272-1281. doi: 10.1093/cercor/bhx040.


Knitting as a Promising Pain Self-Management Strategy for Older Women With Osteoarthritis of the Hand.

Brosseau L, Léonard G.

J Clin Rheumatol. 2017 Apr;23(3):179-180. doi: 10.1097/RHU.0000000000000503. No abstract available.


Efficacy of transcranial direct-current stimulation in women with provoked vestibulodynia.

Morin A, Léonard G, Gougeon V, Cyr MP, Waddell G, Bureau YA, Girard I, Morin M.

Am J Obstet Gynecol. 2017 Jun;216(6):584.e1-584.e11. doi: 10.1016/j.ajog.2017.02.049. Epub 2017 Mar 14.


Unravelling the effect of experimental pain on the corticomotor system using transcranial magnetic stimulation and electroencephalography.

Martel M, Harvey MP, Houde F, Balg F, Goffaux P, Léonard G.

Exp Brain Res. 2017 Apr;235(4):1223-1231. doi: 10.1007/s00221-017-4880-0. Epub 2017 Feb 10.


Classifications In Brief: American Spinal Injury Association (ASIA) Impairment Scale.

Roberts TT, Leonard GR, Cepela DJ.

Clin Orthop Relat Res. 2017 May;475(5):1499-1504. doi: 10.1007/s11999-016-5133-4. Epub 2016 Nov 4. No abstract available.


Association Between Falls and Brain Subvolumes: Results from a Cross-Sectional Analysis in Healthy Older Adults.

Beauchet O, Launay CP, Barden J, Liu-Ambrose T, Chester VL, Szturm T, Grenier S, Léonard G, Bherer L, Annweiler C, Helbostad JL, Verghese J, Allali G; Biomathics and Canadian Gait Consortium.

Brain Topogr. 2017 Mar;30(2):272-280. doi: 10.1007/s10548-016-0533-z. Epub 2016 Oct 26.


Glycerophosphocholine Metabolites and Cardiovascular Disease Risk Factors in Adolescents: A Cohort Study.

Syme C, Czajkowski S, Shin J, Abrahamowicz M, Leonard G, Perron M, Richer L, Veillette S, Gaudet D, Strug L, Wang Y, Xu H, Taylor G, Paus T, Bennett S, Pausova Z.

Circulation. 2016 Nov 22;134(21):1629-1636. Epub 2016 Oct 18.


A fungal pathogen secretes plant alkalinizing peptides to increase infection.

Masachis S, Segorbe D, Turrà D, Leon-Ruiz M, Fürst U, El Ghalid M, Leonard G, López-Berges MS, Richards TA, Felix G, Di Pietro A.

Nat Microbiol. 2016 Apr 11;1(6):16043. doi: 10.1038/nmicrobiol.2016.43.


Anti-Dementia Drugs, Gait Performance and Mental Imagery of Gait: A Non-Randomized Open-Label Trial.

Beauchet O, Barden J, Liu-Ambrose T, Chester VL, Annweiler C, Szturm T, Grenier S, Léonard G, Bherer L, Allali G; Canadian Gait Consortium.

Drugs Aging. 2016 Sep;33(9):665-73. doi: 10.1007/s40266-016-0391-0.


RoboDiff: combining a sample changer and goniometer for highly automated macromolecular crystallography experiments.

Nurizzo D, Bowler MW, Caserotto H, Dobias F, Giraud T, Surr J, Guichard N, Papp G, Guijarro M, Mueller-Dieckmann C, Flot D, McSweeney S, Cipriani F, Theveneau P, Leonard GA.

Acta Crystallogr D Struct Biol. 2016 Aug;72(Pt 8):966-75. doi: 10.1107/S205979831601158X. Epub 2016 Jul 27.


Efficacy of transcranial direct-current stimulation (tDCS) in women with provoked vestibulodynia: study protocol for a randomized controlled trial.

Morin A, Léonard G, Gougeon V, Waddell G, Bureau YA, Girard I, Morin M.

Trials. 2016 May 14;17(1):243. doi: 10.1186/s13063-016-1366-5.


Age- and sex-related variations in vocal-tract morphology and voice acoustics during adolescence.

Markova D, Richer L, Pangelinan M, Schwartz DH, Leonard G, Perron M, Pike GB, Veillette S, Chakravarty MM, Pausova Z, Paus T.

Horm Behav. 2016 May;81:84-96. doi: 10.1016/j.yhbeh.2016.03.001. Epub 2016 Apr 8.


Cohort Profile: The Saguenay Youth Study (SYS).

Pausova Z, Paus T, Abrahamowicz M, Bernard M, Gaudet D, Leonard G, Peron M, Pike GB, Richer L, Séguin JR, Veillette S.

Int J Epidemiol. 2017 Apr 1;46(2):e19. doi: 10.1093/ije/dyw023.


Effect of pulsed electromagnetic field therapy on experimental pain: A double-blind, randomized study in healthy young adults.

Beaulieu K, Beland P, Pinard M, Handfield G, Handfield N, Goffaux P, Corriveau H, Léonard G.

Electromagn Biol Med. 2016;35(3):237-44. doi: 10.3109/15368378.2015.1075409. Epub 2016 Mar 25.


Facilitating best practices in collecting anomalous scattering data for de novo structure solution at the ESRF Structural Biology Beamlines.

de Sanctis D, Oscarsson M, Popov A, Svensson O, Leonard G.

Acta Crystallogr D Struct Biol. 2016 Mar;72(Pt 3):413-20. doi: 10.1107/S2059798316001042. Epub 2016 Mar 1.


[Greenlight(®) photoselective vaporization of the prostate: Contemporary practices in France].

Pradere B, Peyronnet B, Leonard G; GUGL, Misrai V, Bruyère F.

Prog Urol. 2016 Mar;26(3):168-75. doi: 10.1016/j.purol.2016.01.003. Epub 2016 Feb 11. French.


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