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Items: 14


N-Glycosylation regulates ligand-dependent activation and signaling of vascular endothelial growth factor receptor 2 (VEGFR2).

Chandler KB, Leon DR, Kuang J, Meyer RD, Rahimi N, Costello CE.

J Biol Chem. 2019 Aug 30;294(35):13117-13130. doi: 10.1074/jbc.RA119.008643. Epub 2019 Jul 15.


Altered Domain Structure of the Prion Protein Caused by Cu2+ Binding and Functionally Relevant Mutations: Analysis by Cross-Linking, MS/MS, and NMR.

McDonald AJ, Leon DR, Markham KA, Wu B, Heckendorf CF, Schilling K, Showalter HD, Andrews PC, McComb ME, Pushie MJ, Costello CE, Millhauser GL, Harris DA.

Structure. 2019 Jun 4;27(6):907-922.e5. doi: 10.1016/j.str.2019.03.008. Epub 2019 Apr 4.


Oligomannose Glycopeptide Conjugates Elicit Antibodies Targeting the Glycan Core Rather than Its Extremities.

Nguyen DN, Xu B, Stanfield RL, Bailey JK, Horiya S, Temme JS, Leon DR, LaBranche CC, Montefiori DC, Costello CE, Wilson IA, Krauss IJ.

ACS Cent Sci. 2019 Feb 27;5(2):237-249. doi: 10.1021/acscentsci.8b00588. Epub 2019 Feb 6.


Multi-isotype Glycoproteomic Characterization of Serum Antibody Heavy Chains Reveals Isotype- and Subclass-Specific N-Glycosylation Profiles.

Chandler KB, Mehta N, Leon DR, Suscovich TJ, Alter G, Costello CE.

Mol Cell Proteomics. 2019 Apr;18(4):686-703. doi: 10.1074/mcp.RA118.001185. Epub 2019 Jan 18.


O-Fucosylation of thrombospondin-like repeats is required for processing of microneme protein 2 and for efficient host cell invasion by Toxoplasma gondii tachyzoites.

Bandini G, Leon DR, Hoppe CM, Zhang Y, Agop-Nersesian C, Shears MJ, Mahal LK, Routier FH, Costello CE, Samuelson J.

J Biol Chem. 2019 Feb 8;294(6):1967-1983. doi: 10.1074/jbc.RA118.005179. Epub 2018 Dec 11.


Apicomplexan C-Mannosyltransferases Modify Thrombospondin Type I-containing Adhesins of the TRAP Family.

Hoppe CM, Albuquerque-Wendt A, Bandini G, Leon DR, Shcherbakova A, Buettner FFR, Izquierdo L, Costello CE, Bakker H, Routier FH.

Glycobiology. 2018 May 1;28(5):333-343. doi: 10.1093/glycob/cwy013.


Microfluidic Capillary Electrophoresis-Mass Spectrometry for Analysis of Monosaccharides, Oligosaccharides, and Glycopeptides.

Khatri K, Klein JA, Haserick JR, Leon DR, Costello CE, McComb ME, Zaia J.

Anal Chem. 2017 Jun 20;89(12):6645-6655. doi: 10.1021/acs.analchem.7b00875. Epub 2017 Jun 6.


Asparagine-Linked Glycans of Cryptosporidium parvum Contain a Single Long Arm, Are Barely Processed in the Endoplasmic Reticulum (ER) or Golgi, and Show a Strong Bias for Sites with Threonine.

Haserick JR, Leon DR, Samuelson J, Costello CE.

Mol Cell Proteomics. 2017 Apr;16(4 suppl 1):S42-S53. doi: 10.1074/mcp.M116.066035. Epub 2017 Feb 8.


Site-Specific N-Glycosylation of Endothelial Cell Receptor Tyrosine Kinase VEGFR-2.

Chandler KB, Leon DR, Meyer RD, Rahimi N, Costello CE.

J Proteome Res. 2017 Feb 3;16(2):677-688. doi: 10.1021/acs.jproteome.6b00738. Epub 2016 Dec 29.


Immunogenic HLA-DR-Presented Self-Peptides Identified Directly from Clinical Samples of Synovial Tissue, Synovial Fluid, or Peripheral Blood in Patients with Rheumatoid Arthritis or Lyme Arthritis.

Wang Q, Drouin EE, Yao C, Zhang J, Huang Y, Leon DR, Steere AC, Costello CE.

J Proteome Res. 2017 Jan 6;16(1):122-136. doi: 10.1021/acs.jproteome.6b00386. Epub 2016 Nov 7.


Mining proteomic data to expose protein modifications in Methanosarcina mazei strain Gö1.

Leon DR, Ytterberg AJ, Boontheung P, Kim U, Loo JA, Gunsalus RP, Ogorzalek Loo RR.

Front Microbiol. 2015 Mar 5;6:149. doi: 10.3389/fmicb.2015.00149. eCollection 2015.


Workflow for combined proteomics and glycomics profiling from histological tissues.

Turiák L, Shao C, Meng L, Khatri K, Leymarie N, Wang Q, Pantazopoulos H, Leon DR, Zaia J.

Anal Chem. 2014 Oct 7;86(19):9670-8. doi: 10.1021/ac5022216. Epub 2014 Sep 24.


Confident assignment of site-specific glycosylation in complex glycoproteins in a single step.

Khatri K, Staples GO, Leymarie N, Leon DR, Turiák L, Huang Y, Yip S, Hu H, Heckendorf CF, Zaia J.

J Proteome Res. 2014 Oct 3;13(10):4347-55. doi: 10.1021/pr500506z. Epub 2014 Sep 9.


Identification of the major expressed S-layer and cell surface-layer-related proteins in the model methanogenic archaea: Methanosarcina barkeri Fusaro and Methanosarcina acetivorans C2A.

Rohlin L, Leon DR, Kim U, Loo JA, Ogorzalek Loo RR, Gunsalus RP.

Archaea. 2012;2012:873589. doi: 10.1155/2012/873589. Epub 2012 May 15.

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