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Items: 10

1.

Novel imidazole substituted 6-methylidene-penems as broad-spectrum beta-lactamase inhibitors.

Venkatesan AM, Agarwal A, Abe T, Ushirogochi H, Yamamura I, Kumagai T, Petersen PJ, Weiss WJ, Lenoy E, Yang Y, Shlaes DM, Ryan JL, Mansour TS.

Bioorg Med Chem. 2004 Nov 15;12(22):5807-17.

PMID:
15498657
2.

Hydrophobic acetal and ketal derivatives of mannopeptimycin-alpha and desmethylhexahydromannopeptimycin-alpha: semisynthetic glycopeptides with potent activity against Gram-positive bacteria.

Dushin RG, Wang TZ, Sum PE, He H, Sutherland AG, Ashcroft JS, Graziani EI, Koehn FE, Bradford PA, Petersen PJ, Wheless KL, How D, Torres N, Lenoy EB, Weiss WJ, Lang SA, Projan SJ, Shlaes DM, Mansour TS.

J Med Chem. 2004 Jul 1;47(14):3487-90.

PMID:
15214775
3.

In vivo efficacy and pharmacokinetics of AC98-6446, a novel cyclic glycopeptide, in experimental infection models.

Weiss WJ, Murphy T, Lenoy E, Young M.

Antimicrob Agents Chemother. 2004 May;48(5):1708-12.

4.

Effect of srtA and srtB gene expression on the virulence of Staphylococcus aureus in animal models of infection.

Weiss WJ, Lenoy E, Murphy T, Tardio L, Burgio P, Projan SJ, Schneewind O, Alksne L.

J Antimicrob Chemother. 2004 Mar;53(3):480-6. Epub 2004 Feb 4.

PMID:
14762051
5.

Inhalation efficacy of RFI-641 in an African green monkey model of RSV infection.

Weiss WJ, Murphy T, Lynch ME, Frye J, Buklan A, Gray B, Lenoy E, Mitelman S, O'Connell J, Quartuccio S, Huntley C.

J Med Primatol. 2003 Apr;32(2):82-8.

PMID:
12823630
6.

Novel ether derivatives of mannopeptimycin glycopeptide antibiotic.

Sum PE, How D, Torres N, Petersen PJ, Lenoy EB, Weiss WJ, Mansour TS.

Bioorg Med Chem Lett. 2003 Mar 24;13(6):1151-5.

PMID:
12643932
7.

Mannopeptimycins, new cyclic glycopeptide antibiotics produced by Streptomyces hygroscopicus LL-AC98: antibacterial and mechanistic activities.

Singh MP, Petersen PJ, Weiss WJ, Janso JE, Luckman SW, Lenoy EB, Bradford PA, Testa RT, Greenstein M.

Antimicrob Agents Chemother. 2003 Jan;47(1):62-9.

8.

Structures of the muraymycins, novel peptidoglycan biosynthesis inhibitors.

McDonald LA, Barbieri LR, Carter GT, Lenoy E, Lotvin J, Petersen PJ, Siegel MM, Singh G, Williamson RT.

J Am Chem Soc. 2002 Sep 4;124(35):10260-1.

PMID:
12197711
9.

Staphylococcus aureus sortase mutants defective in the display of surface proteins and in the pathogenesis of animal infections.

Mazmanian SK, Liu G, Jensen ER, Lenoy E, Schneewind O.

Proc Natl Acad Sci U S A. 2000 May 9;97(10):5510-5.

10.

6-(1-Hydroxyalkyl))penam sulfone derivatives as inhibitors of class A and class C beta-lactamases II.

Bitha P, Li Z, Francisco GD, Yang Y, Petersen PJ, Lenoy E, Lin YI.

Bioorg Med Chem Lett. 1999 Apr 5;9(7):997-1002.

PMID:
10230627

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