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Items: 1 to 50 of 88

1.

Quickly-responding C-fibre nociceptors contribute to heat hypersensitivity in the area of secondary hyperalgesia.

Lenoir C, Plaghki L, Mouraux A, van den Broeke EN.

J Physiol. 2018 Jul 10. doi: 10.1113/JP275977. [Epub ahead of print]

PMID:
29992559
2.

Dominant-negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency.

Boutboul D, Kuehn HS, Van de Wyngaert Z, Niemela JE, Callebaut I, Stoddard J, Lenoir C, Barlogis V, Farnarier C, Vely F, Yoshida N, Kojima S, Kanegane H, Hoshino A, Hauck F, Lhermitte L, Asnafi V, Roehrs P, Chen S, Verbsky JW, Calvo KR, Husami A, Zhang K, Roberts J, Amrol D, Sleaseman J, Hsu AP, Holland SM, Marsh R, Fischer A, Fleisher TA, Picard C, Latour S, Rosenzweig SD.

J Clin Invest. 2018 Jun 11. pii: 98164. doi: 10.1172/JCI98164. [Epub ahead of print]

3.

Report of one confirmed generalized seizure and one suspected partial seizure induced by deep continuous theta burst stimulation of the right operculo-insular cortex.

Lenoir C, Algoet M, Vanderclausen C, Peeters A, Santos SF, Mouraux A.

Brain Stimul. 2018 May 8. pii: S1935-861X(18)30151-7. doi: 10.1016/j.brs.2018.05.004. [Epub ahead of print] No abstract available.

PMID:
29805097
4.

Diagnostic Yield of Next-Generation Sequencing in Very Early-Onset Inflammatory Bowel Diseases: A Multicenter Study.

Charbit-Henrion F, Parlato M, Hanein S, Duclaux-Loras R, Nowak J, Begue B, Rakotobe S, Bruneau J, Fourrage C, Alibeu O, Rieux-Laucat F, Lévy E, Stolzenberg MC, Mazerolles F, Latour S, Lenoir C, Fischer A, Picard C, Aloi M, Amil Dias J, Ben Hariz M, Bourrier A, Breuer C, Breton A, Bronski J, Buderus S, Cananzi M, Coopman S, Crémilleux C, Dabadie A, Dumant-Forest C, Egritas Gurkan O, Fabre A, Fischer A, German Diaz M, Gonzalez-Lama Y, Goulet O, Guariso G, Gurcan N, Homan M, Hugot JP, Jeziorski E, Karanika E, Lachaux A, Lewindon P, Lima R, Magro F, Major J, Malamut G, Mas E, Mattyus I, Mearin LM, Melek J, Navas-Lopez VM, Paerregaard A, Pelatan C, Pigneur B, Pinto Pais I, Rebeuh J, Romano C, Siala N, Strisciuglio C, Tempia-Caliera M, Tounian P, Turner D, Urbonas V, Willot S, Ruemmele FM, Cerf-Bensussan N.

J Crohns Colitis. 2018 May 18. doi: 10.1093/ecco-jcc/jjy068. [Epub ahead of print]

PMID:
29788237
5.

Prospective evaluation of the effect of deferasirox on hematologic response in transfusion-dependent patients with low-risk MDS and iron overload.

Rose C, Lenoir C, Gyan E, Hacini M, Amé S, Corront B, Beyne-Rauzy O, Adiko D, Loppinet E, Ali-Ammar N, Laribi K, Wattel E, Dreyfus F, Roué CS, Cheze S.

Eur J Haematol. 2018 May 2. doi: 10.1111/ejh.13088. [Epub ahead of print]

PMID:
29719933
6.

Loss of RASGRP1 in humans impairs T-cell expansion leading to Epstein-Barr virus susceptibility.

Winter S, Martin E, Boutboul D, Lenoir C, Boudjemaa S, Petit A, Picard C, Fischer A, Leverger G, Latour S.

EMBO Mol Med. 2018 Feb;10(2):188-199. doi: 10.15252/emmm.201708292.

7.

A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation.

Naret T, Bignon J, Bernadat G, Benchekroun M, Levaique H, Lenoir C, Dubois J, Pruvost A, Saller F, Borgel D, Manoury B, Leblais V, Darrigrand R, Apcher S, Brion JD, Schmitt E, Leroux FR, Alami M, Hamze A.

Eur J Med Chem. 2018 Jan 1;143:473-490. doi: 10.1016/j.ejmech.2017.11.055. Epub 2017 Dec 2.

PMID:
29202409
8.

Human primary somatosensory cortex is differentially involved in vibrotaction and nociception.

Lenoir C, Huang G, Vandermeeren Y, Hatem SM, Mouraux A.

J Neurophysiol. 2017 Jul 1;118(1):317-330. doi: 10.1152/jn.00615.2016. Epub 2017 Apr 26.

9.

Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors.

Khelifi I, Naret T, Renko D, Hamze A, Bernadat G, Bignon J, Lenoir C, Dubois J, Brion JD, Provot O, Alami M.

Eur J Med Chem. 2017 Feb 15;127:1025-1034. doi: 10.1016/j.ejmech.2016.11.012. Epub 2016 Nov 9.

PMID:
28166995
10.

Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection.

Izawa K, Martin E, Soudais C, Bruneau J, Boutboul D, Rodriguez R, Lenoir C, Hislop AD, Besson C, Touzot F, Picard C, Callebaut I, de Villartay JP, Moshous D, Fischer A, Latour S.

J Exp Med. 2017 Jan;214(1):73-89. doi: 10.1084/jem.20160784. Epub 2016 Dec 23.

11.

Secondary hyperalgesia is mediated by heat-insensitive A-fibre nociceptors.

van den Broeke EN, Lenoir C, Mouraux A.

J Physiol. 2016 Nov 15;594(22):6767-6776. doi: 10.1113/JP272599. Epub 2016 Aug 2.

12.

SLAM-associated protein favors the development of iNKT2 over iNKT17 cells.

Michel ML, Lenoir C, Massot B, Diem S, Pasquier B, Sawa S, Rignault-Bricard R, Lehuen A, Eberl G, Veillette A, Leite-de-Moraes M, Latour S.

Eur J Immunol. 2016 Sep;46(9):2162-74. doi: 10.1002/eji.201646313. Epub 2016 Jul 22.

13.

A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education.

Wu N, Zhong MC, Roncagalli R, Pérez-Quintero LA, Guo H, Zhang Z, Lenoir C, Dong Z, Latour S, Veillette A.

Nat Immunol. 2016 Apr;17(4):387-96. doi: 10.1038/ni.3369. Epub 2016 Feb 15.

PMID:
26878112
14.

Refractory monogenic Crohn's disease due to X-linked inhibitor of apoptosis deficiency.

Coelho R, Peixoto A, Amil-Dias J, Trindade E, Campos M, Magina S, Charbit-Henrion F, Lenoir C, Latour S, Magro F, Macedo G.

Int J Colorectal Dis. 2016 Jun;31(6):1235-6. doi: 10.1007/s00384-015-2442-0. Epub 2015 Nov 19. No abstract available.

PMID:
26584814
15.

SYK expression endows human ZAP70-deficient CD8 T cells with residual TCR signaling.

Hauck F, Blumenthal B, Fuchs S, Lenoir C, Martin E, Speckmann C, Vraetz T, Mannhardt-Laakmann W, Lambert N, Gil M, Borte S, Audrain M, Schwarz K, Lim A, Schamel WW, Fischer A, Ehl S, Rensing-Ehl A, Picard C, Latour S.

Clin Immunol. 2015 Dec;161(2):103-9. doi: 10.1016/j.clim.2015.07.002. Epub 2015 Jul 14.

PMID:
26187144
16.

A novel hypomorphic mutation in STIM1 results in a late-onset immunodeficiency.

Schaballie H, Rodriguez R, Martin E, Moens L, Frans G, Lenoir C, Dutré J, Canioni D, Bossuyt X, Fischer A, Latour S, Meyts I, Picard C.

J Allergy Clin Immunol. 2015 Sep;136(3):816-819.e4. doi: 10.1016/j.jaci.2015.03.009. Epub 2015 Apr 30. No abstract available.

PMID:
25935105
17.

Antiangiogenic-Like Properties of Fermented Extracts of Ayurvedic Medicinal Plants.

Rabhi C, Arcile G, Cariel L, Lenoir C, Bignon J, Wdzieczak-Bakala J, Ouazzani J.

J Med Food. 2015 Sep;18(9):1065-72. doi: 10.1089/jmf.2014.0128. Epub 2015 Jan 21.

PMID:
25608021
18.

Plant immunity in plant-aphid interactions.

Jaouannet M, Rodriguez PA, Thorpe P, Lenoir CJ, MacLeod R, Escudero-Martinez C, Bos JI.

Front Plant Sci. 2014 Dec 1;5:663. doi: 10.3389/fpls.2014.00663. eCollection 2014. Review.

19.

Characterization of Crohn disease in X-linked inhibitor of apoptosis-deficient male patients and female symptomatic carriers.

Aguilar C, Lenoir C, Lambert N, Bègue B, Brousse N, Canioni D, Berrebi D, Roy M, Gérart S, Chapel H, Schwerd T, Siproudhis L, Schäppi M, Al-Ahmari A, Mori M, Yamaide A, Galicier L, Neven B, Routes J, Uhlig HH, Koletzko S, Patel S, Kanegane H, Picard C, Fischer A, Bensussan NC, Ruemmele F, Hugot JP, Latour S.

J Allergy Clin Immunol. 2014 Nov;134(5):1131-41.e9. doi: 10.1016/j.jaci.2014.04.031. Epub 2014 Jun 15.

PMID:
24942515
20.

CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation.

Martin E, Palmic N, Sanquer S, Lenoir C, Hauck F, Mongellaz C, Fabrega S, Nitschké P, Esposti MD, Schwartzentruber J, Taylor N, Majewski J, Jabado N, Wynn RF, Picard C, Fischer A, Arkwright PD, Latour S.

Nature. 2014 Jun 12;510(7504):288-92. doi: 10.1038/nature13386. Epub 2014 May 28. Erratum in: Nature. 2014 Jul 17;511(7509):370.

PMID:
24870241
21.

First total synthesis and stereochemical revision of laxaphycin B and its extension to lyngbyacyclamide A.

Boyaud F, Mahiout Z, Lenoir C, Tang S, Wdzieczak-Bakala J, Witczak A, Bonnard I, Banaigs B, Ye T, Inguimbert N.

Org Lett. 2013 Aug 2;15(15):3898-901. doi: 10.1021/ol401645m. Epub 2013 Jul 15. Erratum in: Org Lett. 2013 Sep 6;15(17):4625.

PMID:
23855751
22.

Design, synthesis and anticancer properties of 5-arylbenzoxepins as conformationally restricted isocombretastatin A-4 analogs.

Rasolofonjatovo E, Provot O, Hamze A, Rodrigo J, Bignon J, Wdzieczak-Bakala J, Lenoir C, Desravines D, Dubois J, Brion JD, Alami M.

Eur J Med Chem. 2013 Apr;62:28-39. doi: 10.1016/j.ejmech.2012.12.042. Epub 2013 Jan 4.

PMID:
23353744
23.

Human iNKT and MAIT cells exhibit a PLZF-dependent proapoptotic propensity that is counterbalanced by XIAP.

Gérart S, Sibéril S, Martin E, Lenoir C, Aguilar C, Picard C, Lantz O, Fischer A, Latour S.

Blood. 2013 Jan 24;121(4):614-23. doi: 10.1182/blood-2012-09-456095. Epub 2012 Dec 6.

24.

Human X-linked variable immunodeficiency caused by a hypomorphic mutation in XIAP in association with a rare polymorphism in CD40LG.

Rigaud S, Lopez-Granados E, Sibéril S, Gloire G, Lambert N, Lenoir C, Synaeve C, Stacey M, Fugger L, Stephan JL, Fischer A, Picard C, Durandy A, Chapel H, Latour S.

Blood. 2011 Jul 14;118(2):252-61. doi: 10.1182/blood-2011-01-328849. Epub 2011 May 4.

25.

Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency).

Pachlopnik Schmid J, Canioni D, Moshous D, Touzot F, Mahlaoui N, Hauck F, Kanegane H, Lopez-Granados E, Mejstrikova E, Pellier I, Galicier L, Galambrun C, Barlogis V, Bordigoni P, Fourmaintraux A, Hamidou M, Dabadie A, Le Deist F, Haerynck F, Ouachée-Chardin M, Rohrlich P, Stephan JL, Lenoir C, Rigaud S, Lambert N, Milili M, Schiff C, Chapel H, Picard C, de Saint Basile G, Blanche S, Fischer A, Latour S.

Blood. 2011 Feb 3;117(5):1522-9. doi: 10.1182/blood-2010-07-298372. Epub 2010 Nov 30.

26.

Design, synthesis, and biological evaluation of the first podophyllotoxin analogues as potential vascular-disrupting agents.

Labruère R, Gautier B, Testud M, Seguin J, Lenoir C, Desbène-Finck S, Helissey P, Garbay C, Chabot GG, Vidal M, Giorgi-Renault S.

ChemMedChem. 2010 Dec 3;5(12):2016-25. doi: 10.1002/cmdc.201000305.

PMID:
20979080
27.

Biochemical and structural analysis of the binding determinants of a vascular endothelial growth factor receptor peptidic antagonist.

Gautier B, Goncalves V, Diana D, Di Stasi R, Teillet F, Lenoir C, Huguenot F, Garbay C, Fattorusso R, D'Andrea LD, Vidal M, Inguimbert N.

J Med Chem. 2010 Jun 10;53(11):4428-40. doi: 10.1021/jm1002167.

PMID:
20462213
28.

Ergonomics, surgeon comfort, and theater checklists in pediatric laparoscopy.

Lenoir C, Steinbrecher H.

J Laparoendosc Adv Surg Tech A. 2010 Apr;20(3):281-91. doi: 10.1089/lap.2009.0226.

PMID:
20059320
29.

Synthesis of aryl phosphates based on pyrimidine and triazine scaffolds.

Courme C, Gresh N, Vidal M, Lenoir C, Garbay C, Florent JC, Bertounesque E.

Eur J Med Chem. 2010 Jan;45(1):244-55. doi: 10.1016/j.ejmech.2009.10.003. Epub 2009 Oct 9.

PMID:
19906464
30.

Cost effectiveness of two therapeutic regimens of infliximab in ankylosing spondylitis: economic evaluation within a randomised controlled trial.

Fautrel B, Benhamou M, Breban M, Roy C, Lenoir C, Trape G, Baleydier A, Ravaud P, Dougados M.

Ann Rheum Dis. 2010 Feb;69(2):424-7. doi: 10.1136/ard.2008.103887. Epub 2009 Sep 9.

PMID:
19740900
31.

Preliminary biological evaluations of new thalidomide analogues for multiple sclerosis application.

Contino-Pépin C, Parat A, Périno S, Lenoir C, Vidal M, Galons H, Karlik S, Pucci B.

Bioorg Med Chem Lett. 2009 Feb 1;19(3):878-81. doi: 10.1016/j.bmcl.2008.11.118. Epub 2008 Dec 7.

PMID:
19103485
32.

Synthetic route to dinuclear platinum(II) complexes [{trans-PtCl(NH3)2}2(mu-L)]2+ (L = aliphatic or heterocyclic diamine) as potential antitumor agents, exploiting the mutual activation of hydroxido ligands and ammonium groups.

Chopard C, Lenoir C, Rizzato S, Vidal M, Arpalahti J, Gabison L, Albinati A, Garbay C, Kozelka J.

Inorg Chem. 2008 Oct 20;47(20):9701-5. doi: 10.1021/ic801251k. Epub 2008 Sep 26.

PMID:
18817377
33.

Poverty and sexual concurrency: a case study of STI risk.

Tsui EK, Leonard L, Lenoir C, Ellen JM.

J Health Care Poor Underserved. 2008 Aug;19(3):758-77. doi: 10.1353/hpu.0.0055.

PMID:
18677069
34.

MD-2 controls bacterial lipopolysaccharide hyporesponsiveness in human intestinal epithelial cells.

Lenoir C, Sapin C, Broquet AH, Jouniaux AM, Bardin S, Gasnereau I, Thomas G, Seksik P, Trugnan G, Masliah J, Bachelet M.

Life Sci. 2008 Feb 27;82(9-10):519-28. doi: 10.1016/j.lfs.2007.12.007. Epub 2007 Dec 17.

PMID:
18215718
35.

Rational design, structure, and biological evaluation of cyclic peptides mimicking the vascular endothelial growth factor.

Goncalves V, Gautier B, Coric P, Bouaziz S, Lenoir C, Garbay C, Vidal M, Inguimbert N.

J Med Chem. 2007 Oct 18;50(21):5135-46. Epub 2007 Sep 27.

PMID:
17900101
36.

Hsp70 negatively controls rotavirus protein bioavailability in caco-2 cells infected by the rotavirus RF strain.

Broquet AH, Lenoir C, Gardet A, Sapin C, Chwetzoff S, Jouniaux AM, Lopez S, Trugnan G, Bachelet M, Thomas G.

J Virol. 2007 Feb;81(3):1297-304. Epub 2006 Nov 1.

37.

What you don't know can hurt you: perceptions of sex-partner concurrency and partner-reported behavior.

Lenoir CD, Adler NE, Borzekowski DL, Tschann JM, Ellen JM.

J Adolesc Health. 2006 Mar;38(3):179-85.

PMID:
16488813
39.

Exploring hyperpolarized 83Kr by remotely detected NMR relaxometry.

Cleveland ZI, Pavlovskaya GE, Stupic KF, LeNoir CF, Meersmann T.

J Chem Phys. 2006 Jan 28;124(4):044312.

PMID:
16460167
40.
41.

Design of peptoid analogue dimers and measure of their affinity for Grb2 SH3 domains.

Vidal M, Liu WQ, Lenoir C, Salzmann J, Gresh N, Garbay C.

Biochemistry. 2004 Jun 15;43(23):7336-44.

PMID:
15182177
42.

Constitutive cardiac overexpression of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase delays myocardial failure after myocardial infarction in rats at a cost of increased acute arrhythmias.

Chen Y, Escoubet B, Prunier F, Amour J, Simonides WS, Vivien B, Lenoir C, Heimburger M, Choqueux C, Gellen B, Riou B, Michel JB, Franz WM, Mercadier JJ.

Circulation. 2004 Apr 20;109(15):1898-903. Epub 2004 Mar 22.

43.

Structure-activity relationships of small phosphopeptides, inhibitors of Grb2 SH2 domain, and their prodrugs.

Liu WQ, Vidal M, Olszowy C, Million E, Lenoir C, Dhôtel H, Garbay C.

J Med Chem. 2004 Feb 26;47(5):1223-33.

PMID:
14971902
44.

1-benzyl-2-acetamido-2-deoxy-alpha-D-galactopyranoside blocks the apical biosynthetic pathway in polarized HT-29 cells.

Delacour D, Gouyer V, Leteurtre E, Ait-Slimane T, Drobecq H, Lenoir C, Moreau-Hannedouche O, Trugnan G, Huet G.

J Biol Chem. 2003 Sep 26;278(39):37799-809. Epub 2003 Jul 10.

45.

Incidence of drug-induced hepatic injuries: a French population-based study.

Sgro C, Clinard F, Ouazir K, Chanay H, Allard C, Guilleminet C, Lenoir C, Lemoine A, Hillon P.

Hepatology. 2002 Aug;36(2):451-5.

PMID:
12143055
46.

A novel short peptide is a specific inhibitor of the human immunodeficiency virus type 1 integrase.

de Soultrait VR, Caumont A, Parissi V, Morellet N, Ventura M, Lenoir C, Litvak S, Fournier M, Roques B.

J Mol Biol. 2002 Apr 19;318(1):45-58.

PMID:
12054767
47.

Characterization of a di-leucine-based signal in the cytoplasmic tail of the nucleotide-pyrophosphatase NPP1 that mediates basolateral targeting but not endocytosis.

Bello V, Goding JW, Greengrass V, Sali A, Dubljevic V, Lenoir C, Trugnan G, Maurice M.

Mol Biol Cell. 2001 Oct;12(10):3004-15.

48.

The cytoplasmic/transmembrane domain of dipeptidyl peptidase IV, a type II glycoprotein, contains an apical targeting signal that does not specifically interact with lipid rafts.

Slimane TA, Lenoir C, Bello V, Delaunay JL, Goding JW, Chwetzoff S, Maurice M, Fransen JA, Trugnan G.

Exp Cell Res. 2001 Oct 15;270(1):45-55.

PMID:
11597126
49.

High-throughput fluorogenic assay for determination of botulinum type B neurotoxin protease activity.

Anne C, Cornille F, Lenoir C, Roques BP.

Anal Biochem. 2001 Apr 15;291(2):253-61.

PMID:
11401299
50.

Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2.

Jacotot E, Ferri KF, El Hamel C, Brenner C, Druillennec S, Hoebeke J, Rustin P, Métivier D, Lenoir C, Geuskens M, Vieira HL, Loeffler M, Belzacq AS, Briand JP, Zamzami N, Edelman L, Xie ZH, Reed JC, Roques BP, Kroemer G.

J Exp Med. 2001 Feb 19;193(4):509-19.

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