Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 126

1.

Clinical utility of a protein-based oncopanel in patients with end-stage head and neck cancer.

Doescher J, Weissinger SE, Schönsteiner SS, Lisson C, Bullinger L, Barth TF, Leithäuser F, Mueller-Richter U, Laban S, Hoffmann TK, Möller P, Lennerz JK, Schuler PJ.

Immunotherapy. 2019 Oct;11(14):1193-1203. doi: 10.2217/imt-2019-0041. Epub 2019 Aug 29.

PMID:
31462115
2.

Novel and established EWSR1 gene fusions and associations identified by next generation sequencing and fluorescence in-situ hybridization.

Krystel-Whittemore M, Taylor MS, Rivera M, Lennerz JK, Le LP, Dias-Santagata D, Iafrate AJ, Deshpande V, Chebib I, Nielsen GP, Wu CL, Nardi V.

Hum Pathol. 2019 Aug 17. pii: S0046-8177(19)30139-X. doi: 10.1016/j.humpath.2019.08.006. [Epub ahead of print]

PMID:
31430493
3.

The impact of SOCS1 mutations in diffuse large B-cell lymphoma.

Mellert K, Martin M, Lennerz JK, Lüdeke M, Staiger AM, Kreuz M, Löffler M, Schmitz N, Trümper L, Feller AC, Hartmann S, Hansmann ML, Klapper W, Stein H, Rosenwald A, Ott G, Ziepert M, Möller P.

Br J Haematol. 2019 Aug 12. doi: 10.1111/bjh.16147. [Epub ahead of print]

PMID:
31407320
4.

Treatment with Next-Generation ALK Inhibitors Fuels Plasma ALK Mutation Diversity.

Dagogo-Jack I, Rooney MM, Lin JJ, Nagy RJ, Yeap BY, Hubbeling H, Chin E, Ackil J, Farago AF, Hata AN, Lennerz JK, Gainor JF, Lanman RB, Shaw AT.

Clin Cancer Res. 2019 Jul 29. pii: clincanres.1436.2019. doi: 10.1158/1078-0432.CCR-19-1436. [Epub ahead of print]

PMID:
31358542
5.

Integrative Molecular Characterization of Resistance to Neoadjuvant Chemoradiation in Rectal Cancer.

Kamran SC, Lennerz JK, Margolis CA, Liu D, Reardon B, Wankowicz SA, Van Seventer EE, Tracy A, Wo JY, Carter SL, Willers H, Corcoran RB, Hong TS, Van Allen EM.

Clin Cancer Res. 2019 Sep 15;25(18):5561-5571. doi: 10.1158/1078-0432.CCR-19-0908. Epub 2019 Jun 28.

PMID:
31253631
6.

TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion-Positive Intrahepatic Cholangiocarcinoma.

Goyal L, Shi L, Liu LY, Fece de la Cruz F, Lennerz JK, Raghavan S, Leschiner I, Elagina L, Siravegna G, Ng RWS, Vu P, Patra KC, Saha SK, Uppot RN, Arellano R, Reyes S, Sagara T, Otsuki S, Nadres B, Shahzade HA, Dey-Guha I, Fetter IJ, Baiev I, Van Seventer EE, Murphy JE, Ferrone CR, Tanabe KK, Deshpande V, Harding JJ, Yaeger R, Kelley RK, Bardelli A, Iafrate AJ, Hahn WC, Benes CH, Ting DT, Hirai H, Getz G, Juric D, Zhu AX, Corcoran RB, Bardeesy N.

Cancer Discov. 2019 Aug;9(8):1064-1079. doi: 10.1158/2159-8290.CD-19-0182. Epub 2019 May 20.

PMID:
31109923
7.

Ultra-rapid drug delivery in the oral cavity using ultrasound.

France MM, Del Rio T, Travers H, Raftery E, Xu K, Langer R, Traverso G, Lennerz JK, Schoellhammer CM.

J Control Release. 2019 Jun 28;304:1-6. doi: 10.1016/j.jconrel.2019.04.037. Epub 2019 Apr 27.

PMID:
31039376
8.

Clinical Validation of a Cell-Free DNA Gene Panel.

Cheng J, Cao Y, MacLeay A, Lennerz JK, Baig A, Frazier RP, Lee J, Hu K, Pacula M, Meneses E, Robinson H, Batten JM, Brastianos PK, Heist RS, Bardia A, Le LP, Iafrate AJ.

J Mol Diagn. 2019 Jul;21(4):632-645. doi: 10.1016/j.jmoldx.2019.02.008. Epub 2019 Apr 23.

PMID:
31026600
9.

Clinically Integrated Molecular Diagnostics in Adenoid Cystic Carcinoma.

Thierauf J, Ramamurthy N, Jo VY, Robinson H, Frazier RP, Gonzalez J, Pacula M, Dominguez Meneses E, Nose V, Nardi V, Dias-Santagata D, Le LP, Lin DT, Faquin WC, Wirth LJ, Hess J, Iafrate AJ, Lennerz JK.

Oncologist. 2019 Mar 29. pii: theoncologist.2018-0515. doi: 10.1634/theoncologist.2018-0515. [Epub ahead of print]

PMID:
30926674
10.

Highly Multiplexed Fluorescence in Situ Hybridization for in Situ Genomics.

Onozato ML, Yapp C, Richardson D, Sundaresan T, Chahal V, Lee J, Sullivan JP, Madden MW, Shim HS, Liebers M, Ho Q, Maheswaran S, Haber DA, Zheng Z, Clancy B, Elliott HL, Lennerz JK, Iafrate AJ.

J Mol Diagn. 2019 May;21(3):390-407. doi: 10.1016/j.jmoldx.2019.01.010. Epub 2019 Mar 9.

PMID:
30862547
11.

Molecular Analysis of Plasma From Patients With ROS1-Positive NSCLC.

Dagogo-Jack I, Rooney M, Nagy RJ, Lin JJ, Chin E, Ferris LA, Ackil J, Lennerz JK, Lanman RB, Gainor JF, Shaw AT.

J Thorac Oncol. 2019 May;14(5):816-824. doi: 10.1016/j.jtho.2019.01.009. Epub 2019 Jan 18.

PMID:
30664990
12.

Expediting Comprehensive Molecular Analysis to Optimize Initial Treatment of Lung Cancer Patients With Minimal Smoking History.

Dagogo-Jack I, Robinson H, Mino-Kenudson M, Farago AF, Kamesan V, Iafrate AJ, Shaw AT, Lennerz JK.

J Thorac Oncol. 2019 May;14(5):835-843. doi: 10.1016/j.jtho.2018.12.032. Epub 2019 Jan 18.

PMID:
30660796
13.

Clinicopathological and molecular features of SF3B1-mutated myeloproliferative neoplasms.

Boiocchi L, Hasserjian RP, Pozdnyakova O, Wong WJ, Lennerz JK, Le LP, Dias-Santagata D, Iafrate AJ, Hobbs GS, Nardi V.

Hum Pathol. 2019 Apr;86:1-11. doi: 10.1016/j.humpath.2018.11.022. Epub 2018 Dec 27.

PMID:
30594750
14.

Implementing the DICOM Standard for Digital Pathology.

Herrmann MD, Clunie DA, Fedorov A, Doyle SW, Pieper S, Klepeis V, Le LP, Mutter GL, Milstone DS, Schultz TJ, Kikinis R, Kotecha GK, Hwang DH, Andriole KP, Iafrate AJ, Brink JA, Boland GW, Dreyer KJ, Michalski M, Golden JA, Louis DN, Lennerz JK.

J Pathol Inform. 2018 Nov 2;9:37. doi: 10.4103/jpi.jpi_42_18. eCollection 2018.

15.

Financially effective test algorithm to identify an aggressive, EGFR-amplified variant of IDH-wildtype, lower-grade diffuse glioma.

Bale TA, Jordan JT, Rapalino O, Ramamurthy N, Jessop N, DeWitt JC, Nardi V, Alvarez MM, Frosch M, Batchelor TT, Louis DN, Iafrate AJ, Cahill DP, Lennerz JK.

Neuro Oncol. 2019 May 6;21(5):596-605. doi: 10.1093/neuonc/noy201.

PMID:
30496526
16.

Management of disseminated intravascular coagulation in a patient with hepatic angiosarcoma: A case report.

Rosen EA, Vallurupalli M, Choy E, Lennerz JK, Kuter DJ.

Medicine (Baltimore). 2018 Nov;97(47):e13321. doi: 10.1097/MD.0000000000013321.

17.

Amyloid precursor protein-fragments-containing inclusions in cardiomyocytes with basophilic degeneration and its association with cerebral amyloid angiopathy and myocardial fibrosis.

Krämer LM, Brettschneider J, Lennerz JK, Walcher D, Fang L, Rosenbohm A, Balakrishnan K, Benckendorff J, Möller P, Just S, Willem M, Ludolph AC, Thal DR.

Sci Rep. 2018 Nov 9;8(1):16594. doi: 10.1038/s41598-018-34808-7.

18.

Enrichment of HER2 Amplification in Brain Metastases from Primary Gastrointestinal Malignancies.

Mitra D, Clark JW, Shih HA, Oh KS, Brastianos PK, Wo JY, Strickland MR, Curry WT, Parikh AR, Corcoran RB, Ryan DP, Iafrate AJ, Borger DR, Lennerz JK, Hong TS.

Oncologist. 2019 Feb;24(2):193-201. doi: 10.1634/theoncologist.2018-0152. Epub 2018 Oct 29.

PMID:
30373904
19.

Clinical Utility of Rapid EGFR Genotyping in Advanced Lung Cancer.

Dagogo-Jack I, Azzolli CG, Fintelmann F, Mino-Kenudson M, Farago AF, Gainor JF, Jiang G, Piotrowska Z, Heist RS, Lennes IT, Temel JS, Mooradian MJ, Lin JJ, Digumarthy SR, Batten JM, Robinson H, Nose V, Rivera M, Nardi V, Dias-Santagata D, Le LP, Sequist LV, Pitman M, Shepard JO, Shaw AT, Iafrate AJ, Lennerz JK.

JCO Precis Oncol. 2018;2018. doi: 10.1200/PO.17.00299. Epub 2018 Jul 24.

20.

Artificial Intelligence Approach for Variant Reporting.

Zomnir MG, Lipkin L, Pacula M, Meneses ED, MacLeay A, Duraisamy S, Nadhamuni N, Al Turki SH, Zheng Z, Rivera M, Nardi V, Dias-Santagata D, Iafrate AJ, Le LP, Lennerz JK.

JCO Clin Cancer Inform. 2018;2. doi: 10.1200/CCI.16.00079. Epub 2018 Mar 22.

21.

Recent advances in the histological and molecular classification of endometrial stromal neoplasms.

Ferreira J, Félix A, Lennerz JK, Oliva E.

Virchows Arch. 2018 Dec;473(6):665-678. doi: 10.1007/s00428-018-2470-6. Epub 2018 Oct 15. Review.

PMID:
30324234
22.

Landscape of Acquired Resistance to Osimertinib in EGFR-Mutant NSCLC and Clinical Validation of Combined EGFR and RET Inhibition with Osimertinib and BLU-667 for Acquired RET Fusion.

Piotrowska Z, Isozaki H, Lennerz JK, Gainor JF, Lennes IT, Zhu VW, Marcoux N, Banwait MK, Digumarthy SR, Su W, Yoda S, Riley AK, Nangia V, Lin JJ, Nagy RJ, Lanman RB, Dias-Santagata D, Mino-Kenudson M, Iafrate AJ, Heist RS, Shaw AT, Evans EK, Clifford C, Ou SI, Wolf B, Hata AN, Sequist LV.

Cancer Discov. 2018 Dec;8(12):1529-1539. doi: 10.1158/2159-8290.CD-18-1022. Epub 2018 Sep 26.

PMID:
30257958
23.

The Amount of Bifidobacterium Genus in Colorectal Carcinoma Tissue in Relation to Tumor Characteristics and Clinical Outcome.

Kosumi K, Hamada T, Koh H, Borowsky J, Bullman S, Twombly TS, Nevo D, Masugi Y, Liu L, da Silva A, Chen Y, Du C, Gu M, Li C, Li W, Liu H, Shi Y, Mima K, Song M, Nosho K, Nowak JA, Nishihara R, Baba H, Zhang X, Wu K, Wang M, Huttenhower C, Garrett WS, Meyerson ML, Lennerz JK, Giannakis M, Chan AT, Meyerhardt JA, Fuchs CS, Ogino S.

Am J Pathol. 2018 Dec;188(12):2839-2852. doi: 10.1016/j.ajpath.2018.08.015. Epub 2018 Sep 20.

PMID:
30243655
24.

Impact of BRAF Mutation Class on Disease Characteristics and Clinical Outcomes in BRAF-mutant Lung Cancer.

Dagogo-Jack I, Martinez P, Yeap BY, Ambrogio C, Ferris LA, Lydon C, Nguyen T, Jessop NA, Iafrate AJ, Johnson BE, Lennerz JK, Shaw AT, Awad MM.

Clin Cancer Res. 2019 Jan 1;25(1):158-165. doi: 10.1158/1078-0432.CCR-18-2062. Epub 2018 Sep 17.

PMID:
30224342
25.

Clinicopathologic Features of Non-Small-Cell Lung Cancer Harboring an NTRK Gene Fusion.

Farago AF, Taylor MS, Doebele RC, Zhu VW, Kummar S, Spira AI, Boyle TA, Haura EB, Arcila ME, Benayed R, Aisner DL, Horick NK, Lennerz JK, Le LP, Iafrate AJ, Ou SI, Shaw AT, Mino-Kenudson M, Drilon A.

JCO Precis Oncol. 2018;2018. doi: 10.1200/PO.18.00037. Epub 2018 Jul 23.

26.

Novel gene fusions in secretory carcinoma of the salivary glands: enlarging the ETV6 family.

Guilmette J, Dias-Santagata D, Nosé V, Lennerz JK, Sadow PM.

Hum Pathol. 2019 Jan;83:50-58. doi: 10.1016/j.humpath.2018.08.011. Epub 2018 Aug 18.

PMID:
30130630
27.

Genotype-targeted local therapy of glioma.

Shankar GM, Kirtane AR, Miller JJ, Mazdiyasni H, Rogner J, Tai T, Williams EA, Higuchi F, Juratli TA, Tateishi K, Koerner MVA, Tummala SS, Fink AL, Penson T, Schmidt SP, Wojtkiewicz GR, Baig A, Francis JM, Rinne ML, Batten JM, Batchelor TT, Brastianos PK, Curry WT Jr, Barker FG 2nd, Jordan JT, Iafrate AJ, Chi AS, Lennerz JK, Meyerson M, Langer R, Wakimoto H, Traverso G, Cahill DP.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8388-E8394. doi: 10.1073/pnas.1805751115. Epub 2018 Aug 6.

28.

Brigatinib in Patients With Alectinib-Refractory ALK-Positive NSCLC.

Lin JJ, Zhu VW, Schoenfeld AJ, Yeap BY, Saxena A, Ferris LA, Dagogo-Jack I, Farago AF, Taber A, Traynor A, Menon S, Gainor JF, Lennerz JK, Plodkowski AJ, Digumarthy SR, Ou SI, Shaw AT, Riely GJ.

J Thorac Oncol. 2018 Oct;13(10):1530-1538. doi: 10.1016/j.jtho.2018.06.005. Epub 2018 Jun 20.

PMID:
29935304
29.

Sequential ALK Inhibitors Can Select for Lorlatinib-Resistant Compound ALK Mutations in ALK-Positive Lung Cancer.

Yoda S, Lin JJ, Lawrence MS, Burke BJ, Friboulet L, Langenbucher A, Dardaei L, Prutisto-Chang K, Dagogo-Jack I, Timofeevski S, Hubbeling H, Gainor JF, Ferris LA, Riley AK, Kattermann KE, Timonina D, Heist RS, Iafrate AJ, Benes CH, Lennerz JK, Mino-Kenudson M, Engelman JA, Johnson TW, Hata AN, Shaw AT.

Cancer Discov. 2018 Jun;8(6):714-729. doi: 10.1158/2159-8290.CD-17-1256. Epub 2018 Apr 12.

30.

MET Amplification in Esophageal Squamous Carcinoma.

Michaels PD, Robinson H, Nardi V, Iafrate AJ, Le L, Lennerz JK.

Int J Surg Pathol. 2018 Dec;26(8):731-732. doi: 10.1177/1066896918764301. Epub 2018 Mar 19. No abstract available.

PMID:
29552946
31.

Implementing Keytruda/Pembrolizumab Testing in Clinical Practice.

Ratner D, Lennerz JK.

Oncologist. 2018 Jun;23(6):647-649. doi: 10.1634/theoncologist.2017-0591. Epub 2018 Mar 9. No abstract available.

32.

Tracking the Evolution of Resistance to ALK Tyrosine Kinase Inhibitors through Longitudinal Analysis of Circulating Tumor DNA.

Dagogo-Jack I, Brannon AR, Ferris LA, Campbell CD, Lin JJ, Schultz KR, Ackil J, Stevens S, Dardaei L, Yoda S, Hubbeling H, Digumarthy SR, Riester M, Hata AN, Sequist LV, Lennes IT, Iafrate AJ, Heist RS, Azzoli CG, Farago AF, Engelman JA, Lennerz JK, Benes CH, Leary RJ, Shaw AT, Gainor JF.

JCO Precis Oncol. 2018;2018. doi: 10.1200/PO.17.00160. Epub 2018 Jan 23.

33.

Performance comparison of two androgen receptor splice variant 7 (AR-V7) detection methods.

Bernemann C, Steinestel J, Humberg V, Bögemann M, Schrader AJ, Lennerz JK.

BJU Int. 2018 Aug;122(2):219-226. doi: 10.1111/bju.14146. Epub 2018 Feb 14.

34.

Food Addiction, High-Glycemic-Index Carbohydrates, and Obesity.

Lennerz B, Lennerz JK.

Clin Chem. 2018 Jan;64(1):64-71. doi: 10.1373/clinchem.2017.273532. Epub 2017 Nov 20. Review.

35.

Fluorescent Labeling and 2-Photon Imaging of Mouse Tooth Pulp Nociceptors.

Kadala A, Sotelo-Hitschfeld P, Ahmad Z, Tripal P, Schmid B, Mueller A, Bernal L, Winter Z, Brauchi S, Lohbauer U, Messlinger K, Lennerz JK, Zimmermann K.

J Dent Res. 2018 Apr;97(4):460-466. doi: 10.1177/0022034517740577. Epub 2017 Nov 12.

PMID:
29130364
36.

Cost-effectiveness of IDH testing in diffuse gliomas according to the 2016 WHO classification of tumors of the central nervous system recommendations.

DeWitt JC, Jordan JT, Frosch MP, Samore WR, Iafrate AJ, Louis DN, Lennerz JK.

Neuro Oncol. 2017 Nov 29;19(12):1640-1650. doi: 10.1093/neuonc/nox120.

38.

Origins of lymphatic and distant metastases in human colorectal cancer.

Naxerova K, Reiter JG, Brachtel E, Lennerz JK, van de Wetering M, Rowan A, Cai T, Clevers H, Swanton C, Nowak MA, Elledge SJ, Jain RK.

Science. 2017 Jul 7;357(6346):55-60. doi: 10.1126/science.aai8515.

39.

Case 10-2017 - A 6-Month-Old Boy with Gastrointestinal Bleeding and Abdominal Pain.

Allister LM, Lim R, Goldstein AM, Lennerz JK.

N Engl J Med. 2017 Mar 30;376(13):1269-1277. doi: 10.1056/NEJMcpc1616020. No abstract available.

PMID:
28355500
40.

PAX8-positive Biphasic Synovial Sarcoma Expressing Hormonal Receptors.

Lordello L, Bur ME, Oliva E, Lennerz JK.

Appl Immunohistochem Mol Morphol. 2019 Aug;27(7):e71-e74. doi: 10.1097/PAI.0000000000000497.

PMID:
28248726
41.

ROS1 Fusions Rarely Overlap with Other Oncogenic Drivers in Non-Small Cell Lung Cancer.

Lin JJ, Ritterhouse LL, Ali SM, Bailey M, Schrock AB, Gainor JF, Ferris LA, Mino-Kenudson M, Miller VA, Iafrate AJ, Lennerz JK, Shaw AT.

J Thorac Oncol. 2017 May;12(5):872-877. doi: 10.1016/j.jtho.2017.01.004. Epub 2017 Jan 11.

42.

Polyclonal Secondary FGFR2 Mutations Drive Acquired Resistance to FGFR Inhibition in Patients with FGFR2 Fusion-Positive Cholangiocarcinoma.

Goyal L, Saha SK, Liu LY, Siravegna G, Leshchiner I, Ahronian LG, Lennerz JK, Vu P, Deshpande V, Kambadakone A, Mussolin B, Reyes S, Henderson L, Sun JE, Van Seventer EE, Gurski JM Jr, Baltschukat S, Schacher-Engstler B, Barys L, Stamm C, Furet P, Ryan DP, Stone JR, Iafrate AJ, Getz G, Porta DG, Tiedt R, Bardelli A, Juric D, Corcoran RB, Bardeesy N, Zhu AX.

Cancer Discov. 2017 Mar;7(3):252-263. doi: 10.1158/2159-8290.CD-16-1000. Epub 2016 Dec 29.

43.

Case 35-2016. A 62-Year-Old Man with Dysphagia.

Kwak EL, Hong TS, Forcione DG, Kambadakone A, Lennerz JK.

N Engl J Med. 2016 Nov 17;375(20):1983-1991. No abstract available.

PMID:
27959609
44.

Performance Testing of RREB1, MYB, and CCND1 Fluorescence In Situ Hybridization in Spindle-Cell and Desmoplastic Melanoma Argues for a Two-Step Test Algorithm.

Weissinger SE, Frick M, Möller P, Horst BA, Lennerz JK.

Int J Surg Pathol. 2017 Apr;25(2):148-157. doi: 10.1177/1066896916680072. Epub 2016 Nov 30.

PMID:
27899693
45.

Expression of Kallikrein-Related Peptidase 6 in Primary Mucosal Malignant Melanoma of the Head and Neck.

Thierauf J, Veit JA, Lennerz JK, Weissinger SE, Affolter A, Döscher J, Bergmann C, Knopf A, Grünow J, Grünmüller L, Mauch C, Plinkert PK, Hoffmann TK, Hess J.

Head Neck Pathol. 2017 Sep;11(3):314-320. doi: 10.1007/s12105-016-0769-7. Epub 2016 Nov 14.

47.

Reply from Authors re: Emmanuel S. Antonarakis, Howard I. Scher. Do Patients With AR-V7-Positive Prostate Cancer Benefit from Novel Hormonal Therapies? It All Depends on Definitions. Eur Urol 2017;71:4-6: Unsplicing a Conflict.

Steinestel J, Bernemann C, Schrader AJ, Lennerz JK.

Eur Urol. 2017 Jan;71(1):6-7. doi: 10.1016/j.eururo.2016.08.071. Epub 2016 Sep 15. No abstract available.

PMID:
27641787
48.

Classical pathology and mutational load of breast cancer - integration of two worlds.

Budczies J, Bockmayr M, Denkert C, Klauschen F, Lennerz JK, Györffy B, Dietel M, Loibl S, Weichert W, Stenzinger A.

J Pathol Clin Res. 2015 Jul 20;1(4):225-38. doi: 10.1002/cjp2.25. eCollection 2015 Oct.

49.

Health Care Infrastructure for Financially Sustainable Clinical Genomics.

Lennerz JK, McLaughlin HM, Baron JM, Rasmussen D, Sumbada Shin M, Berners-Lee N, Miller Batten J, Swoboda KJ, Gala MK, Winter HS, Schmahmann JD, Sweetser DA, Boswell M, Pacula M, Stenzinger A, Le LP, Hynes W, Rehm HL, Klibanski A, Black-Schaffer SW, Golden JA, Louis DN, Weiss ST, Iafrate AJ.

J Mol Diagn. 2016 Sep;18(5):697-706. doi: 10.1016/j.jmoldx.2016.04.003. Epub 2016 Jul 25.

50.

Biopanel identifies expression status of targetable proteins in sinonasal melanoma.

Grünmüller L, Thierauf J, Weissinger SE, Bergmann C, Bankfalvi A, Veit J, Hoffmann TK, Möller P, Lennerz JK.

Per Med. 2016 Jul;13(4):291-301. doi: 10.2217/pme-2016-0023. Epub 2016 Apr 20.

PMID:
29749817

Supplemental Content

Loading ...
Support Center