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Anthracycline Cardiotoxicity: It Is Possible to Teach an Old Dog Some New Tricks.

Alvarez-Cardona J, Lenihan DJ.

Cardiol Clin. 2019 Nov;37(4):355-363. doi: 10.1016/j.ccl.2019.08.001. Review.


Cardiovascular Toxicities of Immune Checkpoint Inhibitors: JACC Review Topic of the Week.

Ball S, Ghosh RK, Wongsaengsak S, Bandyopadhyay D, Ghosh GC, Aronow WS, Fonarow GC, Lenihan DJ, Bhatt DL.

J Am Coll Cardiol. 2019 Oct 1;74(13):1714-1727. doi: 10.1016/j.jacc.2019.07.079. Review.


Hypertension in the Cardio-Oncology Clinic.

Hassen LJ, Lenihan DJ, Baliga RR.

Heart Fail Clin. 2019 Oct;15(4):487-495. doi: 10.1016/j.hfc.2019.06.010. Review.


Emerging Therapeutics for the Treatment of Light Chain and Transthyretin Amyloidosis.

Zhang KW, Stockerl-Goldstein KE, Lenihan DJ.

JACC Basic Transl Sci. 2019 Jun 24;4(3):438-448. doi: 10.1016/j.jacbts.2019.02.002. eCollection 2019 Jun. Review.


Evaluation of Severe Myalgia Induced by Continuous-Infusion Bumetanide in Patients with Acute Heart Failure.

Xiong L, Chinaeke EE, Lu K, Lenihan DJ, Merritt TE, Cox ZL.

Pharmacotherapy. 2019 Aug;39(8):854-860. doi: 10.1002/phar.2297. Epub 2019 Jul 11.


Prospective Study of Cardiac Events During Proteasome Inhibitor Therapy for Relapsed Multiple Myeloma.

Cornell RF, Ky B, Weiss BM, Dahm CN, Gupta DK, Du L, Carver JR, Cohen AD, Engelhardt BG, Garfall AL, Goodman SA, Harrell SL, Kassim AA, Jadhav T, Jagasia M, Moslehi J, O'Quinn R, Savona MR, Slosky D, Smith A, Stadtmauer EA, Vogl DT, Waxman A, Lenihan D.

J Clin Oncol. 2019 Aug 1;37(22):1946-1955. doi: 10.1200/JCO.19.00231. Epub 2019 Jun 12.


Prevention, Monitoring, and Management of Cardiac Dysfunction in Patients with Metastatic Breast Cancer.

Curigliano G, de Azambuja E, Lenihan D, Calabrò MG, Cardinale D, Cipolla CM.

Oncologist. 2019 May 7. pii: theoncologist.2018-0773. doi: 10.1634/theoncologist.2018-0773. [Epub ahead of print]


Preparing the Cardiovascular Workforce to Care for Oncology Patients: JACC Review Topic of the Week.

Hayek SS, Ganatra S, Lenneman C, Scherrer-Crosbie M, Leja M, Lenihan DJ, Yang E, Ryan TD, Liu J, Carver J, Mousavi N, O'Quinn R, Arnold A, Banchs J, Barac A, Ky B.

J Am Coll Cardiol. 2019 May 7;73(17):2226-2235. doi: 10.1016/j.jacc.2019.02.041. Review.


Feasibility and Outcomes of an Exercise Intervention for Chemotherapy-Induced Heart Failure.

Tsai E, Mouhayar E, Lenihan D, Song J, Durand JB, Fadol A, Massey M, Harrison C, Basen-Engquist K.

J Cardiopulm Rehabil Prev. 2019 May;39(3):199-203. doi: 10.1097/HCR.0000000000000388.


Arterial hypertension in cancer: The elephant in the room.

Tini G, Sarocchi M, Tocci G, Arboscello E, Ghigliotti G, Novo G, Brunelli C, Lenihan D, Volpe M, Spallarossa P.

Int J Cardiol. 2019 Apr 15;281:133-139. doi: 10.1016/j.ijcard.2019.01.082. Epub 2019 Jan 28.


Cardiac Disease After Breast Cancer Treatment: Make Sure to Check Our Blind Spot!

Lenihan DJ.

J Natl Cancer Inst. 2019 Jan 31. doi: 10.1093/jnci/djy219. [Epub ahead of print] No abstract available.


Pooled analysis of cardiac safety in patients with cancer treated with pertuzumab.

Lenihan D, Suter T, Brammer M, Neate C, Ross G, Baselga J.

Ann Oncol. 2019 Jan 9. doi: 10.1093/annonc/mdy533. [Epub ahead of print] No abstract available.


Addressing the Symptom Management Gap in Patients With Cancer and Heart Failure Using the Interactive Voice Response System: A Pilot Study.

Fadol AP, Mendoza TR, Lenihan DJ, Berry DL.

J Adv Pract Oncol. 2018 Mar;9(2):201-214. Epub 2018 Mar 1. Review.


"To B or Not to B"…That Is the Question: Whether We Can Identify Those at Risk for Cardiac Dysfunction During Cancer Therapy.

Lenihan DJ.

JACC Heart Fail. 2018 Dec;6(12):1033-1034. doi: 10.1016/j.jchf.2018.09.010. Epub 2018 Nov 7. No abstract available.


Cardioprotection During Therapeutic Radiation Treatment.

Lenihan DJ, Cuculich P.

Circ Heart Fail. 2018 Aug;11(8):e005294. doi: 10.1161/CIRCHEARTFAILURE.118.005294. No abstract available.


Management of Cancer Therapeutics-Related Cardiac Dysfunction.

Vallakati A, Konda B, Lenihan DJ, Baliga RR.

Heart Fail Clin. 2018 Oct;14(4):553-567. doi: 10.1016/j.hfc.2018.06.004. Epub 2018 Aug 18. Review.


The role of cardiac biomarkers in cardio-oncology.

Riddell E, Lenihan D.

Curr Probl Cancer. 2018 Jul;42(4):375-385. doi: 10.1016/j.currproblcancer.2018.06.012. Epub 2018 Jul 18. Review.


Analysis of carfilzomib cardiovascular safety profile across relapsed and/or refractory multiple myeloma clinical trials.

Chari A, Stewart AK, Russell SD, Moreau P, Herrmann J, Banchs J, Hajek R, Groarke J, Lyon AR, Batty GN, Ro S, Huang M, Iskander KS, Lenihan D.

Blood Adv. 2018 Jul 10;2(13):1633-1644. doi: 10.1182/bloodadvances.2017015545. Review.


Effects of endogenous serum neuregulin-1β on morbidity and mortality in patients with heart failure and left ventricular systolic dysfunction.

Miao J, Huang S, Su YR, Lenneman CA, Wright M, Harrell FE, Sawyer DB, Lenihan DJ.

Biomarkers. 2018 Nov;23(7):704-708. doi: 10.1080/1354750X.2018.1485054. Epub 2018 Aug 17.


Customizing national models for a medical center's population to rapidly identify patients at high risk of 30-day all-cause hospital readmission following a heart failure hospitalization.

Cox ZL, Lai P, Lewis CM, Lindenfeld J, Collins SP, Lenihan DJ.

Heart Lung. 2018 Jul - Aug;47(4):290-296. doi: 10.1016/j.hrtlng.2018.05.012. Epub 2018 May 28.


The relationship between pulmonary artery wedge pressure and pulmonary blood volume derived from contrast echocardiography: A proof-of-concept study.

Monahan K, Lenihan D, Brittain EL, Saliba L, Piana RN, Robison LL, Hudson MM, Armstrong GT.

Echocardiography. 2018 Sep;35(9):1266-1270. doi: 10.1111/echo.14023. Epub 2018 May 14.


Longitudinal Assessment of Vascular Function With Sunitinib in Patients With Metastatic Renal Cell Carcinoma.

Catino AB, Hubbard RA, Chirinos JA, Townsend R, Keefe S, Haas NB, Puzanov I, Fang JC, Agarwal N, Hyman D, Smith AM, Gordon M, Plappert T, Englefield V, Narayan V, Ewer S, ElAmm C, Lenihan D, Ky B.

Circ Heart Fail. 2018 Mar;11(3):e004408. doi: 10.1161/CIRCHEARTFAILURE.117.004408.


That an Ounce of Prevention Is Worth a Pound of Cure Is Certainly True for Patients With Breast Cancer.

Lenihan DJ.

J Oncol Pract. 2018 Apr;14(4):216. doi: 10.1200/JOP.18.00155. No abstract available.


Advances in Treatment of Cardiac Amyloid.

Dahm CN, Cornell RF, Lenihan DJ.

Curr Treat Options Cardiovasc Med. 2018 Apr 7;20(5):37. doi: 10.1007/s11936-018-0631-1. Review.


Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group.

Puzanov I, Diab A, Abdallah K, Bingham CO 3rd, Brogdon C, Dadu R, Hamad L, Kim S, Lacouture ME, LeBoeuf NR, Lenihan D, Onofrei C, Shannon V, Sharma R, Silk AW, Skondra D, Suarez-Almazor ME, Wang Y, Wiley K, Kaufman HL, Ernstoff MS; Society for Immunotherapy of Cancer Toxicity Management Working Group.

J Immunother Cancer. 2017 Nov 21;5(1):95. doi: 10.1186/s40425-017-0300-z.


Recurrent cardiotoxicity potentiated by the interaction of proteasome inhibitor and immunomodulatory therapy for the treatment of multiple myeloma.

Fradley MG, Groarke JD, Laubach J, Alsina M, Lenihan DJ, Cornell RF, Maglio M, Shain KH, Richardson PG, Moslehi J.

Br J Haematol. 2018 Jan;180(2):271-275. doi: 10.1111/bjh.14970. Epub 2017 Oct 19.


What's Next for Acute Heart Failure Research?

Collins SP, Levy PD, Fermann GJ, Givertz MM, Martindale JM, Pang PS, Storrow AB, Diercks DD, Michael Felker G, Fonarow GC, Lanfear DJ, Lenihan DJ, Lindenfeld JM, Frank Peacock W, Sawyer DM, Teerlink JR, Butler J.

Acad Emerg Med. 2018 Jan;25(1):85-93. doi: 10.1111/acem.13331. Epub 2017 Nov 13.


Exercise right heart catheterization for pulmonary hypertension identified on screening echocardiography in adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort.

Armstrong GT, Tolle JJ, Piana R, Santucci A, Leathers J, Ness KK, Mulrooney DA, Green DM, Joshi VM, Robison LL, Hudson MM, Lenihan D.

Pediatr Blood Cancer. 2018 Jan;65(1). doi: 10.1002/pbc.26769. Epub 2017 Aug 26.


Novel pathologic scoring tools predict end-stage kidney disease in light chain (AL) amyloidosis.

Rubinstein S, Cornell RF, Du L, Concepcion B, Goodman S, Harrell S, Horst S, Lenihan D, Slosky D, Fogo A, Langone A.

Amyloid. 2017 Sep;24(3):205-211. doi: 10.1080/13506129.2017.1360272. Epub 2017 Jul 31.


Elevated Cardiovascular Disease Risk in Patients With Chronic Myelogenous Leukemia Seen in Community-based Oncology Practices in the United States.

Coutinho AD, Makenbaeva D, Farrelly E, Landsman-Blumberg PB, Lenihan D.

Clin Lymphoma Myeloma Leuk. 2017 Oct;17(10):676-683. doi: 10.1016/j.clml.2017.06.011. Epub 2017 Jun 17.


The Horizon in Cardio-Oncology: "You Are Only as Good as Your Endothelium".

Lenihan DJ.

J Am Coll Cardiol. 2017 Jul 11;70(2):163-164. doi: 10.1016/j.jacc.2017.05.048. No abstract available.


Clinical utility of single molecule counting technology for quantification of KIM-1 in patients with heart failure and chronic kidney disease.

Miao J, Friedman E, Wu AHB, Todd JA, Estis J, Xu X, Nolan N, Bishop JJ, Lenihan DJ.

Clin Biochem. 2017 Nov;50(16-17):889-895. doi: 10.1016/j.clinbiochem.2017.06.002. Epub 2017 Jun 12.


Cardio-oncology: What is the Best Practice we can all strive for?

Lenihan D.

Int J Cardiol. 2017 Aug 15;241:393-394. doi: 10.1016/j.ijcard.2017.03.136. No abstract available.


Outcomes from Autologous Hematopoietic Cell Transplantation versus Chemotherapy Alone for the Management of Light Chain Amyloidosis.

Oke O, Sethi T, Goodman S, Phillips S, Decker I, Rubinstein S, Concepcion B, Horst S, Jagasia M, Kassim A, Harrell SL, Langone A, Lenihan D, Rawling KT, Slosky D, Cornell RF.

Biol Blood Marrow Transplant. 2017 Sep;23(9):1473-1477. doi: 10.1016/j.bbmt.2017.05.020. Epub 2017 May 22.


Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults.

Wells QS, Veatch OJ, Fessel JP, Joon AY, Levinson RT, Mosley JD, Held EP, Lindsay CS, Shaffer CM, Weeke PE, Glazer AM, Bersell KR, Van Driest SL, Karnes JH, Blair MA, Lagrone LW, Su YR, Bowton EA, Feng Z, Ky B, Lenihan DJ, Fisch MJ, Denny JC, Roden DM.

Pharmacogenet Genomics. 2017 Jul;27(7):247-254. doi: 10.1097/FPC.0000000000000284.


Centers for Medicare and Medicaid Services' readmission reports inaccurately describe an institution's decompensated heart failure admissions.

Cox ZL, Lai P, Lewis CM, Lenihan DJ.

Clin Cardiol. 2017 Sep;40(9):620-625. doi: 10.1002/clc.22711. Epub 2017 May 4.


Cardiomyopathic Toxicity From Chemotherapy: Is There an Opportunity for Preemptive Intervention?

Swiger KJ, Singh J, Lenihan DJ.

Curr Treat Options Cardiovasc Med. 2017 Mar;19(3):20. doi: 10.1007/s11936-017-0517-7. Review.


The six-minute walk test is a valuable measure of functional change following chemotherapy for AL (light-chain) cardiac amyloidosis.

Decker I, Goodman SA, Phillips SE, Lenihan DJ, Cornell RF.

Br J Haematol. 2017 May;177(3):481-483. doi: 10.1111/bjh.14585. Epub 2017 Mar 14. No abstract available.


Cardio-Oncology-A Rapidly Evolving and Expanding Field of Medicine.

Lenihan DJ, Sawyer DB.

Heart Fail Clin. 2017 Apr;13(2):xiii. doi: 10.1016/j.hfc.2017.01.001. No abstract available.


Current Concepts of Cardiac Amyloidosis: Diagnosis, Clinical Management, and the Need for Collaboration.

Ritts AJ, Cornell RF, Swiger K, Singh J, Goodman S, Lenihan DJ.

Heart Fail Clin. 2017 Apr;13(2):409-416. doi: 10.1016/j.hfc.2016.12.003. Review.


ERBB signaling attenuates proinflammatory activation of nonclassical monocytes.

Ryzhov S, Matafonov A, Galindo CL, Zhang Q, Tran TL, Lenihan DJ, Lenneman CG, Feoktistov I, Sawyer DB.

Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H907-H918. doi: 10.1152/ajpheart.00486.2016. Epub 2017 Feb 24.


Cardio-Oncology: Time to Get More Mechanistic.

Moslehi J, Lenihan DJ.

JACC Basic Transl Sci. 2017 Feb 27;2(1):54-55. doi: 10.1016/j.jacbts.2017.01.002. eCollection 2017 Feb. No abstract available.


Prospective Evaluation of Sunitinib-Induced Cardiotoxicity in Patients with Metastatic Renal Cell Carcinoma.

Narayan V, Keefe S, Haas N, Wang L, Puzanov I, Putt M, Catino A, Fang J, Agarwal N, Hyman D, Smith AM, Finkelman BS, Narayan HK, Ewer S, ElAmm C, Lenihan D, Ky B.

Clin Cancer Res. 2017 Jul 15;23(14):3601-3609. doi: 10.1158/1078-0432.CCR-16-2869. Epub 2017 Feb 14.


Cardiac mechanics and dysfunction with anthracyclines in the community: results from the PREDICT study.

Narayan HK, Wei W, Feng Z, Lenihan D, Plappert T, Englefield V, Fisch M, Ky B.

Open Heart. 2017 Jan 16;4(1):e000524. doi: 10.1136/openhrt-2016-000524. eCollection 2017.


A Phase I, Single Ascending Dose Study of Cimaglermin Alfa (Neuregulin 1β3) in Patients With Systolic Dysfunction and Heart Failure.

Lenihan DJ, Anderson SA, Lenneman CG, Brittain E, Muldowney JAS 3rd, Mendes L, Zhao PZ, Iaci J, Frohwein S, Zolty R, Eisen A, Sawyer DB, Caggiano AO.

JACC Basic Transl Sci. 2016 Dec 26;1(7):576-586. doi: 10.1016/j.jacbts.2016.09.005. eCollection 2016 Dec. Review.


Validation of an automated electronic algorithm and "dashboard" to identify and characterize decompensated heart failure admissions across a medical center.

Cox ZL, Lewis CM, Lai P, Lenihan DJ.

Am Heart J. 2017 Jan;183:40-48. doi: 10.1016/j.ahj.2016.10.001. Epub 2016 Oct 6.


Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline Summary.

Armenian SH, Lacchetti C, Lenihan D.

J Oncol Pract. 2017 Apr;13(4):270-275. doi: 10.1200/JOP.2016.018770. Epub 2016 Dec 6. No abstract available.


Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline.

Armenian SH, Lacchetti C, Barac A, Carver J, Constine LS, Denduluri N, Dent S, Douglas PS, Durand JB, Ewer M, Fabian C, Hudson M, Jessup M, Jones LW, Ky B, Mayer EL, Moslehi J, Oeffinger K, Ray K, Ruddy K, Lenihan D.

J Clin Oncol. 2017 Mar 10;35(8):893-911. doi: 10.1200/JCO.2016.70.5400. Epub 2016 Dec 5.


[2016 ESC Position Paper on cancer treatments and cardiovascular toxicity developed under the auspices of the ESC Committee for Practice Guidelines].

Zamorano JL, Lancellotti P, Muñoz DR, Aboyans V, Asteggiano R, Galderisi M, Habib G, Lenihan DJ, Lip GY, Lyon AR, Fernandez TL, Mohty D, Piepoli MF, Tamargo J, Torbicki A, Suter TM.

Kardiol Pol. 2016;74(11):1193-1233. doi: 10.5603/KP.2016.0156. Polish. No abstract available.


Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies: A Scientific Statement From the American Heart Association.

Bozkurt B, Colvin M, Cook J, Cooper LT, Deswal A, Fonarow GC, Francis GS, Lenihan D, Lewis EF, McNamara DM, Pahl E, Vasan RS, Ramasubbu K, Rasmusson K, Towbin JA, Yancy C; American Heart Association Committee on Heart Failure and Transplantation of the Council on Clinical Cardiology; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; Council on Epidemiology and Prevention; and Council on Quality of Care and Outcomes Research.

Circulation. 2016 Dec 6;134(23):e579-e646. Epub 2016 Nov 3. Review. No abstract available. Erratum in: Circulation. 2016 Dec 6;134(23 ):e652.


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