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Items: 14


A Potent and Effective Suicidal Listeria Vaccine Platform.

Hanson WG, Benanti EL, Lemmens EE, Liu W, Skoble J, Leong ML, Rae CS, Fassò M, Brockstedt DG, Chen C, Portnoy DA, Dubensky TW Jr, Lauer P.

Infect Immun. 2019 Jul 23;87(8). pii: e00144-19. doi: 10.1128/IAI.00144-19. Print 2019 Aug.


Recombinant Listeria promotes tumor rejection by CD8+ T cell-dependent remodeling of the tumor microenvironment.

Deng W, Lira V, Hudson TE, Lemmens EE, Hanson WG, Flores R, Barajas G, Katibah GE, Desbien AL, Lauer P, Leong ML, Portnoy DA, Dubensky TW Jr.

Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8179-8184. doi: 10.1073/pnas.1801910115. Epub 2018 Jul 23.


Distinct roles of cytolytic effector molecules for antigen-restricted killing by CTL in vivo.

Janssen EM, Lemmens EE, Gour N, Reboulet RA, Green DR, Schoenberger SP, Pinkoski MJ.

Immunol Cell Biol. 2010 Oct;88(7):761-5. doi: 10.1038/icb.2010.37. Epub 2010 Mar 23.


Suppression of cell-mediated immunity following recognition of phagosome-confined bacteria.

Bahjat KS, Meyer-Morse N, Lemmens EE, Shugart JA, Dubensky TW, Brockstedt DG, Portnoy DA.

PLoS Pathog. 2009 Sep;5(9):e1000568. doi: 10.1371/journal.ppat.1000568. Epub 2009 Sep 4.


Constitutive Activation of the PrfA regulon enhances the potency of vaccines based on live-attenuated and killed but metabolically active Listeria monocytogenes strains.

Lauer P, Hanson B, Lemmens EE, Liu W, Luckett WS, Leong ML, Allen HE, Skoble J, Bahjat KS, Freitag NE, Brockstedt DG, Dubensky TW Jr.

Infect Immun. 2008 Aug;76(8):3742-53. doi: 10.1128/IAI.00390-08. Epub 2008 Jun 9.


Activation of immature hepatic NK cells as immunotherapy for liver metastatic disease.

Bahjat KS, Prell RA, Allen HE, Liu W, Lemmens EE, Leong ML, Portnoy DA, Dubensky TW Jr, Brockstedt DG, Giedlin MA.

J Immunol. 2007 Dec 1;179(11):7376-84.


Cytosolic entry controls CD8+-T-cell potency during bacterial infection.

Bahjat KS, Liu W, Lemmens EE, Schoenberger SP, Portnoy DA, Dubensky TW Jr, Brockstedt DG.

Infect Immun. 2006 Nov;74(11):6387-97. Epub 2006 Sep 5.


Duration of CTL activation regulates IL-2 production required for autonomous clonal expansion.

Spierings DC, Lemmens EE, Grewal K, Schoenberger SP, Green DR.

Eur J Immunol. 2006 Jul;36(7):1707-17.


Protein kinase C-theta is an early survival factor required for differentiation of effector CD8+ T cells.

Barouch-Bentov R, Lemmens EE, Hu J, Janssen EM, Droin NM, Song J, Schoenberger SP, Altman A.

J Immunol. 2005 Oct 15;175(8):5126-34.


CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.

Janssen EM, Droin NM, Lemmens EE, Pinkoski MJ, Bensinger SJ, Ehst BD, Griffith TS, Green DR, Schoenberger SP.

Nature. 2005 Mar 3;434(7029):88-93.


Dynamic programming of CD8+ T lymphocyte responses.

van Stipdonk MJ, Hardenberg G, Bijker MS, Lemmens EE, Droin NM, Green DR, Schoenberger SP.

Nat Immunol. 2003 Apr;4(4):361-5. Epub 2003 Mar 17.


CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes.

Janssen EM, Lemmens EE, Wolfe T, Christen U, von Herrath MG, Schoenberger SP.

Nature. 2003 Feb 20;421(6925):852-6. Epub 2003 Feb 9.


Cutting edge: a crucial role for B7-CD28 in transmitting T help from APC to CTL.

Prilliman KR, Lemmens EE, Palioungas G, Wolfe TG, Allison JP, Sharpe AH, Schoenberger SP.

J Immunol. 2002 Oct 15;169(8):4094-7. Erratum in: J Immunol 2002 Nov 15;169(10):6056.


Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation.

van Stipdonk MJ, Lemmens EE, Schoenberger SP.

Nat Immunol. 2001 May;2(5):423-9.


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