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Items: 1 to 50 of 314

1.

Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair.

Simões FC, Cahill TJ, Kenyon A, Gavriouchkina D, Vieira JM, Sun X, Pezzolla D, Ravaud C, Masmanian E, Weinberger M, Mayes S, Lemieux ME, Barnette DN, Gunadasa-Rohling M, Williams RM, Greaves DR, Trinh LA, Fraser SE, Dallas SL, Choudhury RP, Sauka-Spengler T, Riley PR.

Nat Commun. 2020 Jan 30;11(1):600. doi: 10.1038/s41467-019-14263-2.

2.

Correction: BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway.

Green AL, DeSisto J, Flannery P, Lemma R, Knox A, Lemieux M, Sanford B, O'Rourke R, Ramkissoon S, Jones K, Perry J, Hui X, Moroze E, Balakrishnan I, O'Neill AF, Dunn K, DeRyckere D, Danis E, Safadi A, Gilani A, Hubbell-Engler B, Nuss Z, Levy JMM, Serkova N, Venkataraman S, Graham DK, Foreman N, Ligon K, Jones K, Kung AL, Vibhakar R.

Oncogene. 2020 Jan 22. doi: 10.1038/s41388-020-1155-1. [Epub ahead of print]

PMID:
31969682
3.

Interaction of a Sarcolipin Pentamer and Monomer with the Sarcoplasmic Reticulum Calcium Pump, SERCA.

Glaves JP, Primeau JO, Gorski PA, Espinoza-Fonseca LM, Lemieux MJ, Young HS.

Biophys J. 2020 Jan 21;118(2):518-531. doi: 10.1016/j.bpj.2019.11.3385. Epub 2019 Nov 28.

PMID:
31858977
4.

BPTF regulates growth of adult and pediatric high-grade glioma through the MYC pathway.

Green AL, DeSisto J, Flannery P, Lemma R, Knox A, Lemieux M, Sanford B, O'Rourke R, Ramkissoon S, Jones K, Perry J, Hui X, Moroze E, Balakrishnan I, O'Neill AF, Dunn K, DeRyckere D, Danis E, Safadi A, Gilani A, Hubbell-Engler B, Nuss Z, Levy JMM, Serkova N, Venkataraman S, Graham DK, Foreman N, Ligon K, Jones K, Kung AL, Vibhakar R.

Oncogene. 2019 Dec 16. doi: 10.1038/s41388-019-1125-7. [Epub ahead of print] Erratum in: Oncogene. 2020 Jan 22;:.

PMID:
31844250
5.

Tau interactome analyses in CRISPR-Cas9 engineered neuronal cells reveal ATPase-dependent binding of wild-type but not P301L Tau to non-muscle myosins.

Wang X, Williams D, Müller I, Lemieux M, Dukart R, Maia IBL, Wang H, Woerman AL, Schmitt-Ulms G.

Sci Rep. 2019 Nov 7;9(1):16238. doi: 10.1038/s41598-019-52543-5.

6.

Condensin II protein dysfunction impacts mitochondrial respiration and mitochondrial oxidative stress responses.

Deutschman E, Ward JR, Kumar A, Ray G, Welch N, Lemieux ME, Dasarathy S, Longworth MS.

J Cell Sci. 2019 Nov 20;132(22). pii: jcs233783. doi: 10.1242/jcs.233783.

7.

Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease.

Helsley RN, Varadharajan V, Brown AL, Gromovsky AD, Schugar RC, Ramachandiran I, Fung K, Kabbany MN, Banerjee R, Neumann CK, Finney C, Pathak P, Orabi D, Osborn LJ, Massey W, Zhang R, Kadam A, Sansbury BE, Pan C, Sacks J, Lee RG, Crooke RM, Graham MJ, Lemieux ME, Gogonea V, Kirwan JP, Allende DS, Civelek M, Fox PL, Rudel LL, Lusis AJ, Spite M, Brown JM.

Elife. 2019 Oct 17;8. pii: e49882. doi: 10.7554/eLife.49882.

8.

Deciphering the activation and recognition mechanisms of Staphylococcus aureus response regulator ArlR.

Ouyang Z, Zheng F, Chew JY, Pei Y, Zhou J, Wen K, Han M, Lemieux MJ, Hwang PM, Wen Y.

Nucleic Acids Res. 2019 Dec 2;47(21):11418-11429. doi: 10.1093/nar/gkz891.

9.

Comprehensive in vitro characterization of PD-L1 small molecule inhibitors.

Ganesan A, Ahmed M, Okoye I, Arutyunova E, Babu D, Turnbull WL, Kundu JK, Shields J, Agopsowicz KC, Xu L, Tabana Y, Srivastava N, Zhang G, Moon TC, Belovodskiy A, Hena M, Kandadai AS, Hosseini SN, Hitt M, Walker J, Smylie M, West FG, Siraki AG, Lemieux MJ, Elahi S, Nieman JA, Tyrrell DL, Houghton M, Barakat K.

Sci Rep. 2019 Aug 27;9(1):12392. doi: 10.1038/s41598-019-48826-6.

10.

Targeting B7-1 in immunotherapy.

Chen R, Ganesan A, Okoye I, Arutyunova E, Elahi S, Lemieux MJ, Barakat K.

Med Res Rev. 2020 Mar;40(2):654-682. doi: 10.1002/med.21632. Epub 2019 Aug 25. Review.

PMID:
31448437
11.

Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation.

Stratton MS, Bagchi RA, Felisbino MB, Hirsch RA, Smith HE, Riching AS, Enyart BY, Koch KA, Cavasin MA, Alexanian M, Song K, Qi J, Lemieux ME, Srivastava D, Lam MPY, Haldar SM, Lin CY, McKinsey TA.

Circ Res. 2019 Sep 13;125(7):662-677. doi: 10.1161/CIRCRESAHA.119.315125. Epub 2019 Aug 14.

PMID:
31409188
12.

Trimeric structure of the mouse Kupffer cell C-type lectin receptor Clec4f.

Ouyang Z, Felix J, Zhou J, Pei Y, Ma B, Hwang PM, Lemieux MJ, Gutsche I, Zheng F, Wen Y.

FEBS Lett. 2020 Jan;594(1):189-198. doi: 10.1002/1873-3468.13565. Epub 2019 Aug 9.

PMID:
31369681
13.

The differential effect of sub-micron level HA aggregates on influenza potency assays.

Lemieux M, Lorbetskie B, Luebbert CC, Walrond L, Li C, Li X, Cyr T, Sauvé S, Johnston MJW, Farnsworth A.

Vaccine. 2019 Aug 23;37(36):5276-5287. doi: 10.1016/j.vaccine.2019.07.050. Epub 2019 Jul 20.

PMID:
31337591
14.

Selective Capture and Determination of Receptor-Binding Hemagglutinin in Influenza Vaccine Preparations Using a Coupled Receptor-Binding/RP-HPLC Assay.

Lorbetskie B, Cunningham AM, Lemieux M, Durno L, Farnsworth A, Wang J, Li C, Li X, Gilbert M, Sauvé S, Girard M.

Anal Chem. 2019 Jul 16;91(14):8908-8917. doi: 10.1021/acs.analchem.9b00617. Epub 2019 Jun 28.

PMID:
31251585
15.

Micro-Acoustic-Trap (µAT) for microparticle assembly in 3D.

Vyas V, Lemieux M, Knecht DA, Kolosov OV, Huey BD.

Ultrason Sonochem. 2019 Oct;57:193-202. doi: 10.1016/j.ultsonch.2019.05.010. Epub 2019 May 10.

PMID:
31208614
16.

Pelvic floor muscle training as a treatment for genitourinary syndrome of menopause: A single-arm feasibility study.

Mercier J, Morin M, Zaki D, Reichetzer B, Lemieux MC, Khalifé S, Dumoulin C.

Maturitas. 2019 Jul;125:57-62. doi: 10.1016/j.maturitas.2019.03.002. Epub 2019 Mar 29.

PMID:
31133219
17.

Reactions at Biomembrane Interfaces.

Bondar AN, Lemieux MJ.

Chem Rev. 2019 May 8;119(9):6162-6183. doi: 10.1021/acs.chemrev.8b00596. Epub 2019 Apr 25.

PMID:
31021080
18.

Glutamatergic neurons of the gigantocellular reticular nucleus shape locomotor pattern and rhythm in the freely behaving mouse.

Lemieux M, Bretzner F.

PLoS Biol. 2019 Apr 24;17(4):e2003880. doi: 10.1371/journal.pbio.2003880. eCollection 2019 Apr.

19.

High-throughput Chemical Screening Identifies Focal Adhesion Kinase and Aurora Kinase B Inhibition as a Synergistic Treatment Combination in Ewing Sarcoma.

Wang S, Hwang EE, Guha R, O'Neill AF, Melong N, Veinotte CJ, Conway Saur A, Wuerthele K, Shen M, McKnight C, Alexe G, Lemieux ME, Wang A, Hughes E, Xu X, Boxer MB, Hall MD, Kung A, Berman JN, Davis MI, Stegmaier K, Crompton BD.

Clin Cancer Res. 2019 Jul 15;25(14):4552-4566. doi: 10.1158/1078-0432.CCR-17-0375. Epub 2019 Apr 12.

PMID:
30979745
20.

Regulating the regulator: intramembrane proteolysis of vesicular trafficking proteins and the SERCA regulator phospholamban.

Young HS, Lemieux MJ.

EMBO Rep. 2019 Mar;20(3). pii: e47792. doi: 10.15252/embr.201947792. Epub 2019 Feb 25. No abstract available.

PMID:
30804015
21.

The Phospholamban Pentamer Alters Function of the Sarcoplasmic Reticulum Calcium Pump SERCA.

Glaves JP, Primeau JO, Espinoza-Fonseca LM, Lemieux MJ, Young HS.

Biophys J. 2019 Feb 19;116(4):633-647. doi: 10.1016/j.bpj.2019.01.013. Epub 2019 Jan 22.

PMID:
30712785
22.

Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry.

Lapek JD Jr, Jiang Z, Wozniak JM, Arutyunova E, Wang SC, Lemieux MJ, Gonzalez DJ, O'Donoghue AJ.

Mol Cell Proteomics. 2019 May;18(5):968-981. doi: 10.1074/mcp.TIR118.001099. Epub 2019 Jan 31.

PMID:
30705125
23.

Semisynthesis of an Anticancer DPAGT1 Inhibitor from a Muraymycin Biosynthetic Intermediate.

Mitachi K, Kurosu SM, Eslamimehr S, Lemieux MR, Ishizaki Y, Clemons WM Jr, Kurosu M.

Org Lett. 2019 Feb 15;21(4):876-879. doi: 10.1021/acs.orglett.8b03716. Epub 2019 Jan 30.

24.

Genitourinary syndrome of menopause symptom severity and impact outcome measures: are they reliable and correlated?

Mercier J, Morin M, Reichetzer B, Lemieux MC, Khalifé S, Dumoulin C.

Menopause. 2018 Dec 28;26(6):659-664. doi: 10.1097/GME.0000000000001287.

PMID:
30601453
25.

Heart Regeneration in the Mexican Cavefish.

Stockdale WT, Lemieux ME, Killen AC, Zhao J, Hu Z, Riepsaame J, Hamilton N, Kudoh T, Riley PR, van Aerle R, Yamamoto Y, Mommersteeg MTM.

Cell Rep. 2018 Nov 20;25(8):1997-2007.e7. doi: 10.1016/j.celrep.2018.10.072.

26.

Intrinsic disorder in the regulatory N-terminal domain of diacylglycerol acyltransferase 1 from Brassica napus.

Panigrahi R, Matsui T, Song AH, Caldo KMP, Young HS, Weselake RJ, Lemieux MJ.

Sci Rep. 2018 Nov 12;8(1):16665. doi: 10.1038/s41598-018-34339-1.

27.

The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C.

Li MX, Gelozia S, Danmaliki GI, Wen Y, Liu PB, Lemieux MJ, West FG, Sykes BD, Hwang PM.

Biochem Biophys Rep. 2018 Nov 1;16:145-151. doi: 10.1016/j.bbrep.2018.10.012. eCollection 2018 Dec.

28.

Highlight: Frontiers in Proteolysis.

Lemieux MJ, Denault JB, Overall CM.

Biol Chem. 2018 Nov 27;399(12):1351. doi: 10.1515/hsz-2018-0401. No abstract available.

PMID:
30352023
29.

Understanding Conformational Dynamics of Complex Lipid Mixtures Relevant to Biology.

Friedman R, Khalid S, Aponte-Santamaría C, Arutyunova E, Becker M, Boyd KJ, Christensen M, Coimbra JTS, Concilio S, Daday C, van Eerden FJ, Fernandes PA, Gräter F, Hakobyan D, Heuer A, Karathanou K, Keller F, Lemieux MJ, Marrink SJ, May ER, Mazumdar A, Naftalin R, Pickholz M, Piotto S, Pohl P, Quinn P, Ramos MJ, Schiøtt B, Sengupta D, Sessa L, Vanni S, Zeppelin T, Zoni V, Bondar AN, Domene C.

J Membr Biol. 2018 Dec;251(5-6):609-631. doi: 10.1007/s00232-018-0050-y. Epub 2018 Oct 22. Review.

30.

Properties and Biotechnological Applications of Acyl-CoA:diacylglycerol Acyltransferase and Phospholipid:diacylglycerol Acyltransferase from Terrestrial Plants and Microalgae.

Xu Y, Caldo KMP, Pal-Nath D, Ozga J, Lemieux MJ, Weselake RJ, Chen G.

Lipids. 2018 Jul;53(7):663-688. doi: 10.1002/lipd.12081. Epub 2018 Sep 25. Review.

PMID:
30252128
31.

An antimycobacterial pleuromutilin analogue effective against dormant bacilli.

Lemieux MR, Siricilla S, Mitachi K, Eslamimehr S, Wang Y, Yang D, Pressly JD, Kong Y, Park F, Franzblau SG, Kurosu M.

Bioorg Med Chem. 2018 Sep 15;26(17):4787-4796. doi: 10.1016/j.bmc.2018.07.034. Epub 2018 Aug 18.

32.

Comparing and Contrasting the Effects of Drosophila Condensin II Subunit dCAP-D3 Overexpression and Depletion in Vivo.

Deutschman E, Ward JR, Ho-A-Lim KT, Alban TJ, Zhang D, Willard B, Lemieux ME, Lathia JD, Longworth MS.

Genetics. 2018 Oct;210(2):531-546. doi: 10.1534/genetics.118.301344. Epub 2018 Aug 1.

33.

The Effect of an Automated Phone Warning and Health Advisory System on Adaptation to High Heat Episodes and Health Services Use in Vulnerable Groups-Evidence from a Randomized Controlled Study.

Mehiriz K, Gosselin P, Tardif I, Lemieux MA.

Int J Environ Res Public Health. 2018 Jul 25;15(8). pii: E1581. doi: 10.3390/ijerph15081581.

34.

An internally quenched peptide as a new model substrate for rhomboid intramembrane proteases.

Arutyunova E, Jiang Z, Yang J, Kulepa AN, Young HS, Verhelst S, O'Donoghue AJ, Lemieux MJ.

Biol Chem. 2018 Nov 27;399(12):1389-1397. doi: 10.1515/hsz-2018-0255.

PMID:
30044760
35.

Diacylglycerol acyltransferase 1 is activated by phosphatidate and inhibited by SnRK1-catalyzed phosphorylation.

Caldo KMP, Shen W, Xu Y, Hanley-Bowdoin L, Chen G, Weselake RJ, Lemieux MJ.

Plant J. 2018 Oct;96(2):287-299. doi: 10.1111/tpj.14029. Epub 2018 Aug 24.

36.

Test-retest reliability of clitoral blood flow measurements using color Doppler ultrasonography at rest and after a pelvic floor contraction task in healthy adult women.

Mercier J, Tang A, Morin M, Khalifé S, Lemieux MC, Reichetzer B, Dumoulin C.

Neurourol Urodyn. 2018 Sep;37(7):2249-2256. doi: 10.1002/nau.23582. Epub 2018 Jun 28.

PMID:
29953674
37.

DSCAM Mutation Impairs Motor Cortex Network Dynamic and Voluntary Motor Functions.

Laflamme OD, Lemieux M, Thiry L, Bretzner F.

Cereb Cortex. 2019 Jun 1;29(6):2313-2330. doi: 10.1093/cercor/bhy097.

PMID:
29718256
38.

Genetic variation in human carboxylesterase CES1 confers resistance to hepatic steatosis.

Lian J, Bahitham W, Panigrahi R, Nelson R, Li L, Watts R, Thiesen A, Lemieux MJ, Lehner R.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Jul;1863(7):688-699. doi: 10.1016/j.bbalip.2018.04.002. Epub 2018 Apr 7.

PMID:
29631096
39.

Taking a position on intramembrane proteolysis.

Lemieux MJ.

J Biol Chem. 2018 Mar 30;293(13):4664-4665. doi: 10.1074/jbc.H118.002210. Review.

40.

Test-retest reliability of internal pudendal artery blood flow using color Doppler ultrasound in healthy women.

Mercier J, Tang A, Morin M, Lemieux MC, Khalifé S, Reichetzer B, Dumoulin C.

Int Urogynecol J. 2018 Dec;29(12):1817-1824. doi: 10.1007/s00192-018-3615-5. Epub 2018 Mar 19.

PMID:
29552737
41.

Distinct Contributions of Mesencephalic Locomotor Region Nuclei to Locomotor Control in the Freely Behaving Mouse.

Josset N, Roussel M, Lemieux M, Lafrance-Zoubga D, Rastqar A, Bretzner F.

Curr Biol. 2018 Mar 19;28(6):884-901.e3. doi: 10.1016/j.cub.2018.02.007. Epub 2018 Mar 8.

42.

Novel FR-900493 Analogues That Inhibit the Outgrowth of Clostridium difficile Spores.

Mitachi K, Yun HG, Kurosu SM, Eslamimehr S, Lemieux MR, Klaić L, Clemons WM Jr, Kurosu M.

ACS Omega. 2018 Feb 28;3(2):1726-1739. doi: 10.1021/acsomega.7b01740. Epub 2018 Feb 9.

43.

Constitutive Ras signaling and Ink4a/Arf inactivation cooperate during the development of B-ALL in mice.

Sewastianik T, Jiang M, Sukhdeo K, Patel SS, Roberts K, Kang Y, Alduaij A, Dennis PS, Lawney B, Liu R, Song Z, Xiong J, Zhang Y, Lemieux ME, Pinkus GS, Rich JN, Weinstock DM, Mullighan CG, Sharpless NE, Carrasco RD.

Blood Adv. 2017 Nov 21;1(25):2361-2374. doi: 10.1182/bloodadvances.2017012211. eCollection 2017 Nov 28.

44.

Lessons Learned from Protective Immune Responses to Optimize Vaccines against Cryptosporidiosis.

Lemieux MW, Sonzogni-Desautels K, Ndao M.

Pathogens. 2017 Dec 24;7(1). pii: E2. doi: 10.3390/pathogens7010002. Review.

45.

Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation.

Nitulescu II, Meyer SC, Wen QJ, Crispino JD, Lemieux ME, Levine RL, Pelish HE, Shair MD.

EBioMedicine. 2017 Dec;26:112-125. doi: 10.1016/j.ebiom.2017.11.013. Epub 2017 Nov 21.

46.

Age- and speed-dependent modulation of gaits in DSCAM2J mutant mice.

Thiry L, Lemieux M, Bretzner F.

J Neurophysiol. 2018 Feb 1;119(2):723-737. doi: 10.1152/jn.00471.2017. Epub 2017 Nov 1.

47.

Conformational memory in the association of the transmembrane protein phospholamban with the sarcoplasmic reticulum calcium pump SERCA.

Smeazzetto S, Armanious GP, Moncelli MR, Bak JJ, Lemieux MJ, Young HS, Tadini-Buoninsegni F.

J Biol Chem. 2017 Dec 29;292(52):21330-21339. doi: 10.1074/jbc.M117.794453. Epub 2017 Oct 29.

48.

Adipose tissue inflammation in insulin resistance: review of mechanisms mediating anti-inflammatory effects of omega-3 polyunsaturated fatty acids.

Pahlavani M, Ramalho T, Koboziev I, LeMieux MJ, Jayarathne S, Ramalingam L, Filgueiras LR, Moustaid-Moussa N.

J Investig Med. 2017 Oct;65(7):1021-1027. doi: 10.1136/jim-2017-000535. Epub 2017 Sep 27. Review.

PMID:
28954844
49.

Multiple mechanisms contribute to increased neutral lipid accumulation in yeast producing recombinant variants of plant diacylglycerol acyltransferase 1.

Xu Y, Chen G, Greer MS, Caldo KMP, Ramakrishnan G, Shah S, Wu L, Lemieux MJ, Ozga J, Weselake RJ.

J Biol Chem. 2017 Oct 27;292(43):17819-17831. doi: 10.1074/jbc.M117.811489. Epub 2017 Sep 12.

50.

Diacylglycerol Acyltransferase 1 Is Regulated by Its N-Terminal Domain in Response to Allosteric Effectors.

Caldo KMP, Acedo JZ, Panigrahi R, Vederas JC, Weselake RJ, Lemieux MJ.

Plant Physiol. 2017 Oct;175(2):667-680. doi: 10.1104/pp.17.00934. Epub 2017 Aug 21.

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