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Items: 35


HadD, a novel fatty acid synthase type II protein, is essential for alpha- and epoxy-mycolic acid biosynthesis and mycobacterial fitness.

Lefebvre C, Boulon R, Ducoux M, Gavalda S, Laval F, Jamet S, Eynard N, Lemassu A, Cam K, Bousquet MP, Bardou F, Burlet-Schiltz O, Daffé M, Quémard A.

Sci Rep. 2018 Apr 16;8(1):6034. doi: 10.1038/s41598-018-24380-5.


Impact of the epoxide hydrolase EphD on the metabolism of mycolic acids in mycobacteria.

Madacki J, Laval F, Grzegorzewicz A, Lemassu A, Záhorszká M, Arand M, McNeil M, Daffé M, Jackson M, Lanéelle MA, Korduláková J.

J Biol Chem. 2018 Apr 6;293(14):5172-5184. doi: 10.1074/jbc.RA117.000246. Epub 2018 Feb 22.


Cell wall peptidolipids of Mycobacterium avium: from genetic prediction to exact structure of a nonribosomal peptide.

Bannantine JP, Etienne G, Laval F, Stabel JR, Lemassu A, Daffé M, Bayles DO, Ganneau C, Bonhomme F, Branger M, Cochard T, Bay S, Biet F.

Mol Microbiol. 2017 Aug;105(4):525-539. doi: 10.1111/mmi.13717. Epub 2017 Jun 15.


Functional reconstitution of the Mycobacterium tuberculosis long-chain acyl-CoA carboxylase from multiple acyl-CoA subunits.

Bazet Lyonnet B, Diacovich L, Gago G, Spina L, Bardou F, Lemassu A, Quémard A, Gramajo H.

FEBS J. 2017 Apr;284(7):1110-1125. doi: 10.1111/febs.14046. Epub 2017 Mar 19.


Trehalose Polyphleates Are Produced by a Glycolipid Biosynthetic Pathway Conserved across Phylogenetically Distant Mycobacteria.

Burbaud S, Laval F, Lemassu A, Daffé M, Guilhot C, Chalut C.

Cell Chem Biol. 2016 Feb 18;23(2):278-289. doi: 10.1016/j.chembiol.2015.11.013. Epub 2016 Jan 28.


The Non-Essential Mycolic Acid Biosynthesis Genes hadA and hadC Contribute to the Physiology and Fitness of Mycobacterium smegmatis.

Jamet S, Slama N, Domingues J, Laval F, Texier P, Eynard N, Quémard A, Peixoto A, Lemassu A, Daffé M, Cam K.

PLoS One. 2015 Dec 23;10(12):e0145883. doi: 10.1371/journal.pone.0145883. eCollection 2015.


The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis.

Slama N, Jamet S, Frigui W, Pawlik A, Bottai D, Laval F, Constant P, Lemassu A, Cam K, Daffé M, Brosch R, Eynard N, Quémard A.

Mol Microbiol. 2016 Feb;99(4):794-807. doi: 10.1111/mmi.13266. Epub 2015 Nov 27.


Increased Vancomycin Susceptibility in Mycobacteria: a New Approach To Identify Synergistic Activity against Multidrug-Resistant Mycobacteria.

Soetaert K, Rens C, Wang XM, De Bruyn J, Lanéelle MA, Laval F, Lemassu A, Daffé M, Bifani P, Fontaine V, Lefèvre P.

Antimicrob Agents Chemother. 2015 Aug;59(8):5057-60. doi: 10.1128/AAC.04856-14. Epub 2015 Jun 1.


Functional characterisation of three o-methyltransferases involved in the biosynthesis of phenolglycolipids in Mycobacterium tuberculosis.

Simeone R, Huet G, Constant P, Malaga W, Lemassu A, Laval F, Daffé M, Guilhot C, Chalut C.

PLoS One. 2013;8(3):e58954. doi: 10.1371/journal.pone.0058954. Epub 2013 Mar 11.


Structural elucidation and genomic scrutiny of the C60-C100 mycolic acids of Segniliparus rotundus.

Lanéelle MA, Eynard N, Spina L, Lemassu A, Laval F, Huc E, Etienne G, Marrakchi H, Daffé M.

Microbiology. 2013 Jan;159(Pt 1):191-203. doi: 10.1099/mic.0.063479-0. Epub 2012 Nov 15.


A novel mycolic acid species defines two novel genera of the Actinobacteria, Hoyosella and Amycolicicoccus.

Lanéelle MA, Launay A, Spina L, Marrakchi H, Laval F, Eynard N, Lemassu A, Tropis M, Daffé M, Etienne G.

Microbiology. 2012 Mar;158(Pt 3):843-55. doi: 10.1099/mic.0.055509-0. Epub 2011 Dec 22.


Identification of mycobacterial alpha-glucan as a novel ligand for DC-SIGN: involvement of mycobacterial capsular polysaccharides in host immune modulation.

Geurtsen J, Chedammi S, Mesters J, Cot M, Driessen NN, Sambou T, Kakutani R, Ummels R, Maaskant J, Takata H, Baba O, Terashima T, Bovin N, Vandenbroucke-Grauls CM, Nigou J, Puzo G, Lemassu A, Daffé M, Appelmelk BJ.

J Immunol. 2009 Oct 15;183(8):5221-31. doi: 10.4049/jimmunol.0900768. Epub 2009 Sep 25.


Identification of the polyketide synthase involved in the biosynthesis of the surface-exposed lipooligosaccharides in mycobacteria.

Etienne G, Malaga W, Laval F, Lemassu A, Guilhot C, Daffé M.

J Bacteriol. 2009 Apr;191(8):2613-21. doi: 10.1128/JB.01235-08. Epub 2009 Jan 30.


Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice.

Sambou T, Dinadayala P, Stadthagen G, Barilone N, Bordat Y, Constant P, Levillain F, Neyrolles O, Gicquel B, Lemassu A, Daffé M, Jackson M.

Mol Microbiol. 2008 Nov;70(3):762-74. doi: 10.1111/j.1365-2958.2008.06445.x. Epub 2008 Sep 18.


Comparative structural analyses of the alpha-glucan and glycogen from Mycobacterium bovis.

Dinadayala P, Sambou T, Daffé M, Lemassu A.

Glycobiology. 2008 Jul;18(7):502-8. doi: 10.1093/glycob/cwn031. Epub 2008 Apr 24.


Investigating the function of the putative mycolic acid methyltransferase UmaA: divergence between the Mycobacterium smegmatis and Mycobacterium tuberculosis proteins.

Laval F, Haites R, Movahedzadeh F, Lemassu A, Wong CY, Stoker N, Billman-Jacobe H, Daffé M.

J Biol Chem. 2008 Jan 18;283(3):1419-27. Epub 2007 Nov 15.


Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis.

Stadthagen G, Sambou T, Guerin M, Barilone N, Boudou F, Korduláková J, Charles P, Alzari PM, Lemassu A, Daffé M, Puzo G, Gicquel B, Rivière M, Jackson M.

J Biol Chem. 2007 Sep 14;282(37):27270-6. Epub 2007 Jul 19.


Cell wall-associated alpha-glucan is instrumental for Mycobacterium tuberculosis to block CD1 molecule expression and disable the function of dendritic cell derived from infected monocyte.

Gagliardi MC, Lemassu A, Teloni R, Mariotti S, Sargentini V, Pardini M, Daffé M, Nisini R.

Cell Microbiol. 2007 Aug;9(8):2081-92. Epub 2007 Apr 17.


Glycogen synthesis in the absence of glycogenin in the yeast Saccharomyces cerevisiae.

Torija MJ, Novo M, Lemassu A, Wilson W, Roach PJ, François J, Parrou JL.

FEBS Lett. 2005 Jul 18;579(18):3999-4004.


Characterization of three glycosyltransferases involved in the biosynthesis of the phenolic glycolipid antigens from the Mycobacterium tuberculosis complex.

Pérez E, Constant P, Lemassu A, Laval F, Daffé M, Guilhot C.

J Biol Chem. 2004 Oct 8;279(41):42574-83. Epub 2004 Aug 3.


Molecular dissection of the role of two methyltransferases in the biosynthesis of phenolglycolipids and phthiocerol dimycoserosate in the Mycobacterium tuberculosis complex.

Pérez E, Constant P, Laval F, Lemassu A, Lanéelle MA, Daffé M, Guilhot C.

J Biol Chem. 2004 Oct 8;279(41):42584-92. Epub 2004 Aug 3.


6,6'-Dimycoloyl trehalose from a rapidly growing Mycobacterium: an alternative antigen for tuberculosis serodiagnosis.

López-Marín LM, Segura E, Hermida-Escobedo C, Lemassu A, Salinas-Carmona MC.

FEMS Immunol Med Microbiol. 2003 May 15;36(1-2):47-54.


Tracking the putative biosynthetic precursors of oxygenated mycolates of Mycobacterium tuberculosis. Structural analysis of fatty acids of a mutant strain deviod of methoxy- and ketomycolates.

Dinadayala P, Laval F, Raynaud C, Lemassu A, Laneelle MA, Laneelle G, Daffe M.

J Biol Chem. 2003 Feb 28;278(9):7310-9. Epub 2002 Dec 6.


Priming and activation of mouse macrophages by trehalose 6,6'-dicorynomycolate vesicles from Corynebacterium glutamicum.

Chami M, Andréau K, Lemassu A, Petit JF, Houssin C, Puech V, Bayan N, Chaby R, Daffé M.

FEMS Immunol Med Microbiol. 2002 Jan 14;32(2):141-7.


Structure and antigenicity of the major glycolipid from Taenia solium cysticerci.

López-Marín LM, Montrozier H, Lemassu A, García E, Segura E, Daffé M.

Mol Biochem Parasitol. 2002 Jan;119(1):33-42.


Structure of the cell envelope of corynebacteria: importance of the non-covalently bound lipids in the formation of the cell wall permeability barrier and fracture plane.

Puech V, Chami M, Lemassu A, Lanéelle MA, Schiffler B, Gounon P, Bayan N, Benz R, Daffé M.

Microbiology. 2001 May;147(Pt 5):1365-82.


Extracellular and surface-exposed polysaccharides of non-tuberculous mycobacteria.

Lemassu A, Ortalo-Magné A, Bardou F, Silve G, Laneélle MA, Daffé M.

Microbiology. 1996 Jun;142 ( Pt 6):1513-20.


Identification of the surface-exposed lipids on the cell envelopes of Mycobacterium tuberculosis and other mycobacterial species.

Ortalo-Magné A, Lemassu A, Lanéelle MA, Bardou F, Silve G, Gounon P, Marchal G, Daffé M.

J Bacteriol. 1996 Jan;178(2):456-61.


Molecular composition of the outermost capsular material of the tubercle bacillus.

Ortalo-Magné A, Dupont MA, Lemassu A, Andersen AB, Gounon P, Daffé M.

Microbiology. 1995 Jul;141 ( Pt 7):1609-20.


Lack of correlation between colony morphology and lipooligosaccharide content in the Mycobacterium tuberculosis complex.

Lemassu A, Lévy-Frébault VV, Lanéelle MA, Daffé M.

J Gen Microbiol. 1992 Jul;138(7):1535-41.


Revised structure of a trehalose-containing immunoreactive glycolipid of Mycobacterium tuberculosis.

Lemassu A, Lanéelle MA, Daffé M.

FEMS Microbiol Lett. 1991 Mar 1;62(2-3):171-5.


Lateral proton conduction in monolayers of phospholipids from extreme halophiles.

Teissié J, Prats M, LeMassu A, Stewart LC, Kates M.

Biochemistry. 1990 Jan 9;29(1):59-65.


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