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Items: 45

1.

How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?

Lemaire K, Granvik M, Schraenen A, Goyvaerts L, Van Lommel L, Gómez-Ruiz A, In 't Veld P, Gilon P, Schuit F.

PLoS One. 2017 Aug 9;12(8):e0181651. doi: 10.1371/journal.pone.0181651. eCollection 2017.

2.

Commentary: Validation of a Ramp Running Protocol for Determination of the True VO2max in Mice.

Lemaire KK, Thomasson R, Noirez P, Jaspers RT, van Soest AJ.

Front Physiol. 2017 May 24;8:330. doi: 10.3389/fphys.2017.00330. eCollection 2017. No abstract available.

3.

Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity.

Philippaert K, Pironet A, Mesuere M, Sones W, Vermeiren L, Kerselaers S, Pinto S, Segal A, Antoine N, Gysemans C, Laureys J, Lemaire K, Gilon P, Cuypers E, Tytgat J, Mathieu C, Schuit F, Rorsman P, Talavera K, Voets T, Vennekens R.

Nat Commun. 2017 Mar 31;8:14733. doi: 10.1038/ncomms14733.

4.

Omitted data in randomized controlled trials for anxiety and depression: A systematic review of the inclusion of sexual orientation and gender identity.

Heck NC, Mirabito LA, LeMaire K, Livingston NA, Flentje A.

J Consult Clin Psychol. 2017 Jan;85(1):72-76. doi: 10.1037/ccp0000123. Epub 2016 Jun 16. Review.

5.

Comparison of the validity of Hill and Huxley muscle-tendon complex models using experimental data obtained from rat m. soleus in situ.

Lemaire KK, Baan GC, Jaspers RT, van Soest AJ.

J Exp Biol. 2016 Jul 15;219(Pt 14):2228. doi: 10.1242/jeb.144394. No abstract available.

6.

Disallowed and Allowed Gene Expression: Two Faces of Mature Islet Beta Cells.

Lemaire K, Thorrez L, Schuit F.

Annu Rev Nutr. 2016 Jul 17;36:45-71. doi: 10.1146/annurev-nutr-071715-050808. Epub 2016 May 4. Review.

PMID:
27146011
7.

Comparison of the validity of Hill and Huxley muscle-tendon complex models using experimental data obtained from rat m. soleus in situ.

Lemaire KK, Baan GC, Jaspers RT, van Soest AJ.

J Exp Biol. 2016 Apr;219(Pt 7):977-87. doi: 10.1242/jeb.128280. Epub 2016 Feb 19. Erratum in: J Exp Biol. 2016 Jul 15;219(Pt 14):2228.

8.

Effect of a transcriptional inactive or absent vitamin D receptor on beta-cell function and glucose homeostasis in mice.

Vangoitsenhoven R, Wolden-Kirk H, Lemaire K, Verstuyf A, Verlinden L, Yamamoto Y, Kato S, Van Lommel L, Schuit F, Van der Schueren B, Mathieu C, Overbergh L.

J Steroid Biochem Mol Biol. 2016 Nov;164:309-317. doi: 10.1016/j.jsbmb.2016.02.011. Epub 2016 Feb 11.

PMID:
26877201
9.

Labeling Sexual Victimization Experiences: The Role of Sexism, Rape Myth Acceptance, and Tolerance for Sexual Harassment.

LeMaire KL, Oswald DL, Russell BL.

Violence Vict. 2016;31(2):332-46. doi: 10.1891/0886-6708.VV-D-13-00148. Epub 2016 Jan 29.

PMID:
26832168
10.

Androgen Deficiency Exacerbates High-Fat Diet-Induced Metabolic Alterations in Male Mice.

Dubois V, Laurent MR, Jardi F, Antonio L, Lemaire K, Goyvaerts L, Deldicque L, Carmeliet G, Decallonne B, Vanderschueren D, Claessens F.

Endocrinology. 2016 Feb;157(2):648-65. doi: 10.1210/en.2015-1713. Epub 2015 Nov 12.

PMID:
26562264
11.

Prolactin receptors and placental lactogen drive male mouse pancreatic islets to pregnancy-related mRNA changes.

Goyvaerts L, Lemaire K, Arijs I, Auffret J, Granvik M, Van Lommel L, Binart N, in't Veld P, Schuit F, Schraenen A.

PLoS One. 2015 Mar 27;10(3):e0121868. doi: 10.1371/journal.pone.0121868. eCollection 2015.

12.

The Basic Biology of PP2A in Hematologic Cells and Malignancies.

Haesen D, Sents W, Lemaire K, Hoorne Y, Janssens V.

Front Oncol. 2014 Dec 11;4:347. doi: 10.3389/fonc.2014.00347. eCollection 2014. Review.

13.

Integrated miRNA and mRNA expression profiling in inflamed colon of patients with ulcerative colitis.

Van der Goten J, Vanhove W, Lemaire K, Van Lommel L, Machiels K, Wollants WJ, De Preter V, De Hertogh G, Ferrante M, Van Assche G, Rutgeerts P, Schuit F, Vermeire S, Arijs I.

PLoS One. 2014 Dec 29;9(12):e116117. doi: 10.1371/journal.pone.0116117. eCollection 2014.

14.

Impaired islet function in commonly used transgenic mouse lines due to human growth hormone minigene expression.

Brouwers B, de Faudeur G, Osipovich AB, Goyvaerts L, Lemaire K, Boesmans L, Cauwelier EJ, Granvik M, Pruniau VP, Van Lommel L, Van Schoors J, Stancill JS, Smolders I, Goffin V, Binart N, in't Veld P, Declercq J, Magnuson MA, Creemers JW, Schuit F, Schraenen A.

Cell Metab. 2014 Dec 2;20(6):979-90. doi: 10.1016/j.cmet.2014.11.004.

15.

Mice deficient in the respiratory chain gene Cox6a2 are protected against high-fat diet-induced obesity and insulin resistance.

Quintens R, Singh S, Lemaire K, De Bock K, Granvik M, Schraenen A, Vroegrijk IO, Costa V, Van Noten P, Lambrechts D, Lehnert S, Van Lommel L, Thorrez L, De Faudeur G, Romijn JA, Shelton JM, Scorrano L, Lijnen HR, Voshol PJ, Carmeliet P, Mammen PP, Schuit F.

PLoS One. 2013;8(2):e56719. doi: 10.1371/journal.pone.0056719. Epub 2013 Feb 27.

16.

Integrating insulin secretion and ER stress in pancreatic β-cells.

Lemaire K, Schuit F.

Nat Cell Biol. 2012 Oct;14(10):979-81. doi: 10.1038/ncb2594.

PMID:
23033046
17.

Zinc transporters and their role in the pancreatic β-cell.

Lemaire K, Chimienti F, Schuit F.

J Diabetes Investig. 2012 Jun 6;3(3):202-11. doi: 10.1111/j.2040-1124.2012.00199.x. Review.

18.

β-cell-specific gene repression: a mechanism to protect against inappropriate or maladjusted insulin secretion?

Schuit F, Van Lommel L, Granvik M, Goyvaerts L, de Faudeur G, Schraenen A, Lemaire K.

Diabetes. 2012 May;61(5):969-75. doi: 10.2337/db11-1564. No abstract available.

19.

Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis.

Lemaire K, Moura RF, Granvik M, Igoillo-Esteve M, Hohmeier HE, Hendrickx N, Newgard CB, Waelkens E, Cnop M, Schuit F.

PLoS One. 2011 Apr 6;6(4):e18517. doi: 10.1371/journal.pone.0018517.

20.

Mucosal gene expression of cell adhesion molecules, chemokines, and chemokine receptors in patients with inflammatory bowel disease before and after infliximab treatment.

Arijs I, De Hertogh G, Machiels K, Van Steen K, Lemaire K, Schraenen A, Van Lommel L, Quintens R, Van Assche G, Vermeire S, Schuit F, Rutgeerts P.

Am J Gastroenterol. 2011 Apr;106(4):748-61. doi: 10.1038/ajg.2011.27. Epub 2011 Feb 15.

PMID:
21326222
21.

Pdx1- and Ngn3-Cre-mediated PLAG1 expression in the pancreas leads to endocrine hormone imbalances that affect glucose metabolism.

Declercq J, Kumar A, Gysemans C, Di Pietro C, Schraenen A, Chintinne M, Lemaire K, Van Lommel L, Van De Casteele M, Heimberg H, Pipeleers D, Schuit FC, Mathieu C, Ectors N, Van de Ven WJ, Verfaillie CM.

Cell Transplant. 2011;20(8):1285-97. doi: 10.3727/096368910X550242. Epub 2011 Feb 3.

PMID:
21294959
22.

Tissue-specific disallowance of housekeeping genes: the other face of cell differentiation.

Thorrez L, Laudadio I, Van Deun K, Quintens R, Hendrickx N, Granvik M, Lemaire K, Schraenen A, Van Lommel L, Lehnert S, Aguayo-Mazzucato C, Cheng-Xue R, Gilon P, Van Mechelen I, Bonner-Weir S, Lemaigre F, Schuit F.

Genome Res. 2011 Jan;21(1):95-105. doi: 10.1101/gr.109173.110. Epub 2010 Nov 18.

23.

Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy.

Schraenen A, Lemaire K, de Faudeur G, Hendrickx N, Granvik M, Van Lommel L, Mallet J, Vodjdani G, Gilon P, Binart N, in't Veld P, Schuit F.

Diabetologia. 2010 Dec;53(12):2589-99. doi: 10.1007/s00125-010-1913-7. Epub 2010 Oct 7.

24.

mRNA expression analysis of cell cycle genes in islets of pregnant mice.

Schraenen A, de Faudeur G, Thorrez L, Lemaire K, Van Wichelen G, Granvik M, Van Lommel L, in't Veld P, Schuit F.

Diabetologia. 2010 Dec;53(12):2579-88. doi: 10.1007/s00125-010-1912-8. Epub 2010 Oct 1.

25.

Predictive value of epithelial gene expression profiles for response to infliximab in Crohn's disease.

Arijs I, Quintens R, Van Lommel L, Van Steen K, De Hertogh G, Lemaire K, Schraenen A, Perrier C, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P.

Inflamm Bowel Dis. 2010 Dec;16(12):2090-8. doi: 10.1002/ibd.21301.

PMID:
20848504
26.

Serine-409 phosphorylation and oxidative damage define aggregation of human protein tau in yeast.

Vanhelmont T, Vandebroek T, De Vos A, Terwel D, Lemaire K, Anandhakumar J, Franssens V, Swinnen E, Van Leuven F, Winderickx J.

FEMS Yeast Res. 2010 Dec;10(8):992-1005. doi: 10.1111/j.1567-1364.2010.00662.x.

27.

Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.

Ehses JA, Meier DT, Wueest S, Rytka J, Boller S, Wielinga PY, Schraenen A, Lemaire K, Debray S, Van Lommel L, Pospisilik JA, Tschopp O, Schultze SM, Malipiero U, Esterbauer H, Ellingsgaard H, Rütti S, Schuit FC, Lutz TA, Böni-Schnetzler M, Konrad D, Donath MY.

Diabetologia. 2010 Aug;53(8):1795-806. doi: 10.1007/s00125-010-1747-3. Epub 2010 Apr 21.

PMID:
20407745
28.

Loss of high-frequency glucose-induced Ca2+ oscillations in pancreatic islets correlates with impaired glucose tolerance in Trpm5-/- mice.

Colsoul B, Schraenen A, Lemaire K, Quintens R, Van Lommel L, Segal A, Owsianik G, Talavera K, Voets T, Margolskee RF, Kokrashvili Z, Gilon P, Nilius B, Schuit FC, Vennekens R.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5208-13. doi: 10.1073/pnas.0913107107. Epub 2010 Mar 1.

29.

Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment.

Arijs I, De Hertogh G, Lemaire K, Quintens R, Van Lommel L, Van Steen K, Leemans P, Cleynen I, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P.

PLoS One. 2009 Nov 24;4(11):e7984. doi: 10.1371/journal.pone.0007984.

30.

Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.

Lemaire K, Ravier MA, Schraenen A, Creemers JW, Van de Plas R, Granvik M, Van Lommel L, Waelkens E, Chimienti F, Rutter GA, Gilon P, in't Veld PA, Schuit FC.

Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14872-7. doi: 10.1073/pnas.0906587106. Epub 2009 Aug 18.

31.

Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis.

Arijs I, Li K, Toedter G, Quintens R, Van Lommel L, Van Steen K, Leemans P, De Hertogh G, Lemaire K, Ferrante M, Schnitzler F, Thorrez L, Ma K, Song XY, Marano C, Van Assche G, Vermeire S, Geboes K, Schuit F, Baribaud F, Rutgeerts P.

Gut. 2009 Dec;58(12):1612-9. doi: 10.1136/gut.2009.178665. Epub 2009 Aug 20.

PMID:
19700435
32.

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk.

Bouatia-Naji N, Bonnefond A, Cavalcanti-Proença C, Sparsø T, Holmkvist J, Marchand M, Delplanque J, Lobbens S, Rocheleau G, Durand E, De Graeve F, Chèvre JC, Borch-Johnsen K, Hartikainen AL, Ruokonen A, Tichet J, Marre M, Weill J, Heude B, Tauber M, Lemaire K, Schuit F, Elliott P, Jørgensen T, Charpentier G, Hadjadj S, Cauchi S, Vaxillaire M, Sladek R, Visvikis-Siest S, Balkau B, Lévy-Marchal C, Pattou F, Meyre D, Blakemore AI, Jarvelin MR, Walley AJ, Hansen T, Dina C, Pedersen O, Froguel P.

Nat Genet. 2009 Jan;41(1):89-94. doi: 10.1038/ng.277. Epub 2008 Dec 7.

PMID:
19060909
33.

Why expression of some genes is disallowed in beta-cells.

Quintens R, Hendrickx N, Lemaire K, Schuit F.

Biochem Soc Trans. 2008 Jun;36(Pt 3):300-5. doi: 10.1042/BST0360300.

PMID:
18481946
34.

A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels.

Bouatia-Naji N, Rocheleau G, Van Lommel L, Lemaire K, Schuit F, Cavalcanti-Proença C, Marchand M, Hartikainen AL, Sovio U, De Graeve F, Rung J, Vaxillaire M, Tichet J, Marre M, Balkau B, Weill J, Elliott P, Jarvelin MR, Meyre D, Polychronakos C, Dina C, Sladek R, Froguel P.

Science. 2008 May 23;320(5879):1085-8. doi: 10.1126/science.1156849. Epub 2008 May 1.

35.

Probe-independent and direct quantification of insulin mRNA and growth hormone mRNA in enriched cell preparations.

Van Lommel L, Janssens K, Quintens R, Tsukamoto K, Vander Mierde D, Lemaire K, Denef C, Jonas JC, Martens G, Pipeleers D, Schuit FC.

Diabetes. 2006 Dec;55(12):3214-20.

36.

Identification and isolation of a hyperphosphorylated, conformationally changed intermediate of human protein tau expressed in yeast.

Vandebroek T, Vanhelmont T, Terwel D, Borghgraef P, Lemaire K, Snauwaert J, Wera S, Van Leuven F, Winderickx J.

Biochemistry. 2005 Aug 30;44(34):11466-75.

PMID:
16114883
37.
38.

Sex and sugar in yeast: two distinct GPCR systems.

Versele M, Lemaire K, Thevelein JM.

EMBO Rep. 2001 Jul;2(7):574-9. Review.

39.

A baker's yeast mutant (fil1) with a specific, partially inactivating mutation in adenylate cyclase maintains a high stress resistance during active fermentation and growth.

Van Dijck P, Ma P, Versele M, Gorwa MF, Colombo S, Lemaire K, Bossi D, Loïez A, Thevelein JM.

J Mol Microbiol Biotechnol. 2000 Oct;2(4):521-30.

PMID:
11075928
40.
41.

A gene encoding a sphingolipid biosynthesis enzyme determines the sensitivity of Saccharomyces cerevisiae to an antifungal plant defensin from dahlia (Dahlia merckii).

Thevissen K, Cammue BP, Lemaire K, Winderickx J, Dickson RC, Lester RL, Ferket KK, Van Even F, Parret AH, Broekaert WF.

Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9531-6.

42.

Nutrient-induced signal transduction through the protein kinase A pathway and its role in the control of metabolism, stress resistance, and growth in yeast.

Thevelein JM, Cauwenberg L, Colombo S, De Winde JH, Donation M, Dumortier F, Kraakman L, Lemaire K, Ma P, Nauwelaers D, Rolland F, Teunissen A, Van Dijck P, Versele M, Wera S, Winderickx J.

Enzyme Microb Technol. 2000 Jun 1;26(9-10):819-825.

PMID:
10862891
43.

Characterization of a new set of mutants deficient in fermentation-induced loss of stress resistance for use in frozen dough applications.

Van Dijck P, Gorwa MF, Lemaire K, Teunissen A, Versele M, Colombo S, Dumortier F, Ma P, Tanghe A, Loiez A, Thevelein JM.

Int J Food Microbiol. 2000 Apr 10;55(1-3):187-92. Review.

PMID:
10791742
44.

A Saccharomyces cerevisiae G-protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucose.

Kraakman L, Lemaire K, Ma P, Teunissen AW, Donaton MC, Van Dijck P, Winderickx J, de Winde JH, Thevelein JM.

Mol Microbiol. 1999 Jun;32(5):1002-12.

45.

Weaning test in pulmonary oedema.

Samii K, Lemaire K, Regnier B, Rapin M.

Lancet. 1976 Nov 27;2(7996):1200. No abstract available.

PMID:
63023

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