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Oxygen Conservation Methods With Automated Titration.

Bourassa S, Bouchard PA, Dauphin M, Lellouche F.

Respir Care. 2020 Feb 18. pii: respcare.07240. doi: 10.4187/respcare.07240. [Epub ahead of print]


[A new case of rare erythrocytosis due to EGLN1 mutation with review of the literature].

Bonnin A, Gardie B, Girodon F, Airaud F, Garrec C, Bézieau S, Vignon G, Mottaz P, Labrousse J, Lellouche F.

Rev Med Interne. 2020 Jan 21. pii: S0248-8663(20)30007-2. doi: 10.1016/j.revmed.2019.12.019. [Epub ahead of print] French.


Evaluation of a new respiratory monitoring tool "Early Warning ScoreO2" for patients admitted at the emergency department with dyspnea.

Viglino D, L'her E, Maltais F, Maignan M, Lellouche F.

Resuscitation. 2020 Jan 13;148:59-65. doi: 10.1016/j.resuscitation.2020.01.004. [Epub ahead of print]


Lessening Organ dysfunction with VITamin C (LOVIT): protocol for a randomized controlled trial.

Masse MH, Ménard J, Sprague S, Battista MC, Cook DJ, Guyatt GH, Heyland DK, Kanji S, Pinto R, Day AG, Cohen D, Annane D, McGuinness S, Parke R, Carr A, Arabi Y, Vijayaraghavan BKT, D'Aragon F, Carbonneau É, Maslove D, Hunt M, Rochwerg B, Millen T, Chassé M, Lebrasseur M, Archambault P, Deblois E, Drouin C, Lellouche F, Lizotte P, Watpool I, Porteous R, Clarke F, Marinoff N, Belley-Côté É, Bolduc B, Walker S, Iazzetta J, Adhikari NKJ, Lamontagne F; Canadian Critical Care Trials Group.

Trials. 2020 Jan 8;21(1):42. doi: 10.1186/s13063-019-3834-1.


Hyperoxemia: The Poison Is in the Dose.

Lellouche F, L'Her E.

Am J Respir Crit Care Med. 2020 Feb 15;201(4):498. doi: 10.1164/rccm.201910-1898LE. No abstract available.


Evaluation of hyperoxia-induced hypercapnia in obese patients after cardiac surgery: a randomized crossover comparison of conservative and liberal oxygen administration.

Denault MH, Ruel C, Simon M, Bouchard PA, Simard S, Lellouche F.

Can J Anaesth. 2020 Feb;67(2):194-202. doi: 10.1007/s12630-019-01500-x. Epub 2019 Oct 24.


Diagnostic workup in front of an adult monocytosis.

Labrousse J, Pasini S, Vignon G, Bonnin A, Mottaz P, Carrere F, Augereau PF, Aucher P, Lellouche F.

Ann Biol Clin (Paris). 2019 Oct 1;77(5):485-494. doi: 10.1684/abc.2019.1475.


Monoclonal gammopathy of undetermined significance (MGUS): interpretative shades of analysis and sometimes serious clinical consequences.

Carrère F, Plasse F, Pasini S, Vignon G, Mottaz P, Bonnin A, Augereau PF, Aucher P, Lellouche F.

Ann Biol Clin (Paris). 2019 Jun 1;77(3):245-254. doi: 10.1684/abc.2019.1440. Review.


Impact of Gas Masks on the Work of Breathing and Breathing Pattern in Subjects With Stable COPD.

Bourassa S, Bouchard PA, Lellouche F.

Respir Care. 2019 Sep;64(9):1049-1056. doi: 10.4187/respcare.06550. Epub 2019 Mar 26.


Automated oxygen administration versus conventional oxygen therapy after major abdominal or thoracic surgery: study protocol for an international multicentre randomised controlled study.

L'her E, Jaber S, Verzilli D, Jacob C, Huiban B, Futier E, Kerforne T, Pateau V, Bouchard PA, Gouillou M, Nowak E, Lellouche F.

BMJ Open. 2019 Jan 17;9(1):e023833. doi: 10.1136/bmjopen-2018-023833.


Photoplethysmographic determination of the respiratory rate in acutely ill patients: validation of a new algorithm and implementation into a biomedical device.

L'Her E, N'Guyen QT, Pateau V, Bodenes L, Lellouche F.

Ann Intensive Care. 2019 Jan 21;9(1):11. doi: 10.1186/s13613-019-0485-z.


Diagnostic workup in front of an adult neutropenia.

Bonnin A, Vignon G, Mottaz P, Labrousse J, Carrere F, Augereau PF, Aucher P, Lellouche F.

Ann Biol Clin (Paris). 2018 Dec 1;76(6):651-658. doi: 10.1684/abc.2018.1393. Review.


IgM Myeloma: case report and literature review.

Labrousse J, Plasse F, Aucher P, Augereau P, Bertin A, Carrere F, Cognée AS, Vignon G, Violette J, Lellouche F.

Ann Biol Clin (Paris). 2018 Oct 1;76(5):575-578. doi: 10.1684/abc.2018.1380. Review.


How I do in front of an hemolytic anemia of unknown etiology?

Vignon G, Jeanneau R, Labrousse J, Aubrit S, Mottaz P, Carrère F, Augereau PF, Aucher P, Lellouche F.

Ann Biol Clin (Paris). 2018 Oct 1;76(5):493-503. doi: 10.1684/abc.2018.1381. Review.


Automated O2 titration improves exercise capacity in patients with hypercapnic chronic obstructive pulmonary disease: a randomised controlled cross-over trial.

Vivodtzev I, L'Her E, Vottero G, Yankoff C, Tamisier R, Maltais F, Lellouche F, Pépin JL.

Thorax. 2019 Mar;74(3):298-301. doi: 10.1136/thoraxjnl-2018-211967. Epub 2018 Aug 30.


Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery.

Mazer CD, Whitlock RP, Fergusson DA, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Médicis É, Carrier FM, McGuinness S, Young PJ, Byrne K, Villar JC, Royse A, Grocott HP, Seeberger MD, Mehta C, Lellouche F, Hare GMT, Painter TW, Fremes S, Syed S, Bagshaw SM, Hwang NC, Royse C, Hall J, Dai D, Mistry N, Thorpe K, Verma S, Jüni P, Shehata N; TRICS Investigators and Perioperative Anesthesia Clinical Trials Group.

N Engl J Med. 2018 Sep 27;379(13):1224-1233. doi: 10.1056/NEJMoa1808561. Epub 2018 Aug 26.


Oxygen for Myocardial Infarction: Not an Open Bar!

Lellouche F.

JACC Cardiovasc Interv. 2018 Aug 27;11(16):1598-1600. doi: 10.1016/j.jcin.2018.05.019. No abstract available.


Impact of Gas Masks on Work of Breathing, Breathing Patterns, and Gas Exchange in Healthy Subjects.

Bourassa S, Bouchard PA, Lellouche F.

Respir Care. 2018 Nov;63(11):1350-1359. doi: 10.4187/respcare.06027. Epub 2018 Jul 31.


[A fatal septic shock due to Capnocytophaga canimorsus and review of literature].

Vignon G, Combeau P, Violette J, Cognée AS, Méglio S, Carrère F, Aucher P, Lellouche F.

Rev Med Interne. 2018 Oct;39(10):820-823. doi: 10.1016/j.revmed.2018.03.384. Epub 2018 Apr 26. Review. French.


[Diagnostic workup in front of an atypical non hemolytic anemia].

Colin JY, Vignon G, Mottaz P, Labrousse J, Carrere F, Augereau PF, Aucher P, Lellouche F.

Rev Med Interne. 2018 Nov;39(11):855-862. doi: 10.1016/j.revmed.2018.03.382. Epub 2018 Apr 13. Review. French.


International Practice Variation in Weaning Critically Ill Adults from Invasive Mechanical Ventilation.

Burns KEA, Raptis S, Nisenbaum R, Rizvi L, Jones A, Bakshi J, Tan W, Meret A, Cook DJ, Lellouche F, Epstein SK, Gattas D, Kapadia FN, Villar J, Brochard L, Lessard MR, Meade MO.

Ann Am Thorac Soc. 2018 Apr;15(4):494-502. doi: 10.1513/AnnalsATS.201705-410OC. Erratum in: Ann Am Thorac Soc. 2018 Jul;15(7):894.


The authors reply.

Delorme M, Lellouche F.

Crit Care Med. 2018 Mar;46(3):e275-e276. doi: 10.1097/CCM.0000000000002895. No abstract available.


Effect of position and positive pressure ventilation on functional residual capacity in morbidly obese patients: a randomized trial.

Couture EJ, Provencher S, Somma J, Lellouche F, Marceau S, Bussières JS.

Can J Anaesth. 2018 May;65(5):522-528. doi: 10.1007/s12630-018-1050-1. Epub 2018 Jan 18.


Cost-effectiveness of FreeO2 in patients with chronic obstructive pulmonary disease hospitalised for acute exacerbations: analysis of a pilot study in Quebec.

Poder TG, Kouakou CRC, Bouchard PA, Tremblay V, Blais S, Maltais F, Lellouche F.

BMJ Open. 2018 Jan 23;8(1):e018835. doi: 10.1136/bmjopen-2017-018835.


Oxygen Therapy in Suspected Acute Myocardial Infarction.

Lellouche F, Simon M, L’Her E.

N Engl J Med. 2018 Jan 11;378(2):201. doi: 10.1056/NEJMc1714937. No abstract available.


Transfusion Requirements in Cardiac Surgery III (TRICS III): Study Design of a Randomized Controlled Trial.

Shehata N, Whitlock R, Fergusson DA, Thorpe KE, MacAdams C, Grocott HP, Rubens F, Fremes S, Lellouche F, Bagshaw S, Royse A, Rosseel PM, Hare G, Medicis E, Hudson C, Belley-Cote E, Bainbridge D, Kent B, Shaw A, Byrne K, Syed S, Royse CF, McGuiness S, Hall J, Mazer CD.

J Cardiothorac Vasc Anesth. 2018 Feb;32(1):121-129. doi: 10.1053/j.jvca.2017.10.036. Epub 2017 Nov 3.


Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery.

Mazer CD, Whitlock RP, Fergusson DA, Hall J, Belley-Cote E, Connolly K, Khanykin B, Gregory AJ, de Médicis É, McGuinness S, Royse A, Carrier FM, Young PJ, Villar JC, Grocott HP, Seeberger MD, Fremes S, Lellouche F, Syed S, Byrne K, Bagshaw SM, Hwang NC, Mehta C, Painter TW, Royse C, Verma S, Hare GMT, Cohen A, Thorpe KE, Jüni P, Shehata N; TRICS Investigators and Perioperative Anesthesia Clinical Trials Group.

N Engl J Med. 2017 Nov 30;377(22):2133-2144. doi: 10.1056/NEJMoa1711818. Epub 2017 Nov 12.


Allogeneic Mesenchymal Stem Cells for Treatment of AKI after Cardiac Surgery.

Swaminathan M, Stafford-Smith M, Chertow GM, Warnock DG, Paragamian V, Brenner RM, Lellouche F, Fox-Robichaud A, Atta MG, Melby S, Mehta RL, Wald R, Verma S, Mazer CD; ACT-AKI investigators.

J Am Soc Nephrol. 2018 Jan;29(1):260-267. doi: 10.1681/ASN.2016101150. Epub 2017 Oct 16.


Effects of High-Flow Nasal Cannula on the Work of Breathing in Patients Recovering From Acute Respiratory Failure.

Delorme M, Bouchard PA, Simon M, Simard S, Lellouche F.

Crit Care Med. 2017 Dec;45(12):1981-1988. doi: 10.1097/CCM.0000000000002693.


A new case of IgE multiple myeloma with review of literature.

Vignon G, Cognée AS, Carrere F, Masson I, Borde F, Augereau PF, Aucher P, Lellouche F.

Ann Biol Clin (Paris). 2017 Aug 1;75(4):442-444. doi: 10.1684/abc.2017.1263. Review.


Automatic versus manual oxygen administration in the emergency department.

L'Her E, Dias P, Gouillou M, Riou A, Souquiere L, Paleiron N, Archambault P, Bouchard PA, Lellouche F.

Eur Respir J. 2017 Jul 20;50(1). pii: 1602552. doi: 10.1183/13993003.02552-2016. Print 2017 Jul.


[Two cases of myeloid sarcomas with review of literature].

Mottaz P, Becot-Bretez F, Jeanneau R, Vignon G, Bertin A, Carrere F, Augereau PF, Aucher P, Lellouche F.

Rev Med Interne. 2017 Nov;38(11):774-777. doi: 10.1016/j.revmed.2017.06.002. Epub 2017 Jun 28. Review. French.


Innovations in oxygen therapy

Lellouche F, L'Her E.

Rev Prat. 2017 Nov 20;67(9):941-946. French. No abstract available.


Automatic Oxygen Titration During Walking in Subjects With COPD: A Randomized Crossover Controlled Study.

Lellouche F, L'Her E, Bouchard PA, Brouillard C, Maltais F.

Respir Care. 2016 Nov;61(11):1456-1464. Epub 2016 Oct 18.


Automated oxygen titration and weaning with FreeO2 in patients with acute exacerbation of COPD: a pilot randomized trial.

Lellouche F, Bouchard PA, Roberge M, Simard S, L'Her E, Maltais F, Lacasse Y.

Int J Chron Obstruct Pulmon Dis. 2016 Aug 24;11:1983-90. doi: 10.2147/COPD.S112820. eCollection 2016.


Accuracy of height estimation and tidal volume setting using anthropometric formulas in an ICU Caucasian population.

L'her E, Martin-Babau J, Lellouche F.

Ann Intensive Care. 2016 Dec;6(1):55. doi: 10.1186/s13613-016-0154-4. Epub 2016 Jun 21.


Cerebral Oximetry Monitoring to Maintain Normal Cerebral Oxygen Saturation during High-risk Cardiac Surgery: A Randomized Controlled Feasibility Trial.

Deschamps A, Hall R, Grocott H, Mazer CD, Choi PT, Turgeon AF, de Medicis E, Bussières JS, Hudson C, Syed S, Seal D, Herd S, Lambert J, Denault A, Deschamps A, Mutch A, Turgeon A, Denault A, Todd A, Jerath A, Fayad A, Finnegan B, Kent B, Kennedy B, Cuthbertson BH, Kavanagh B, Warriner B, MacAdams C, Lehmann C, Fudorow C, Hudson C, McCartney C, McIsaac D, Dubois D, Campbell D, Mazer D, Neilpovitz D, Rosen D, Cheng D, Drapeau D, Dillane D, Tran D, Mckeen D, Wijeysundera D, Jacobsohn E, Couture E, de Medicis E, Alam F, Abdallah F, Ralley FE, Chung F, Lellouche F, Dobson G, Germain G, Djaiani G, Gilron I, Hare G, Bryson G, Clarke H, McDonald H, Roman-Smith H, Grocott H, Yang H, Douketis J, Paul J, Beaubien J, Bussières J, Pridham J, Armstrong JN, Parlow J, Murkin J, Gamble J, Duttchen K, Karkouti K, Turner K, Baghirzada L, Szabo L, Lalu M, Wasowicz M, Bautista M, Jacka M, Murphy M, Schmidt M, Verret M, Perrault MA, Beaudet N, Buckley N, Choi P, MacDougall P, Jones P, Drolet P, Beaulieu P, Taneja R, Martin R, Hall R, George R, Chun R, McMullen S, Beattie S, Sampson S, Choi S, Kowalski S, McCluskey S, Syed S, Boet S, Ramsay T, Saha T, Mutter T, Chowdhury T, Uppal V, Mckay W; Canadian Perioperative Anesthesia Clinical Trials Group.

Anesthesiology. 2016 Apr;124(4):826-36. doi: 10.1097/ALN.0000000000001029.


Perioperative ventilatory strategies in cardiac surgery.

Lellouche F, Delorme M, Bussières J, Ouattara A.

Best Pract Res Clin Anaesthesiol. 2015 Sep;29(3):381-95. doi: 10.1016/j.bpa.2015.08.006. Epub 2015 Sep 4. Review.


The Underestimated Belly Factor: Waist Circumference Is Linked to Significant Morbidity Following Isolated Coronary Artery Bypass Grafting.

Chassé M, Mathieu P, Voisine P, Després JP, Pibarot P, Baillot R, Lellouche F, Poirier P.

Can J Cardiol. 2016 Mar;32(3):327-35. doi: 10.1016/j.cjca.2015.06.031. Epub 2015 Jul 7.


Automated weaning and SBT systems versus non-automated weaning strategies for weaning time in invasively ventilated critically ill adults.

Burns KE, Lellouche F, Nisenbaum R, Lessard MR, Friedrich JO.

Cochrane Database Syst Rev. 2014 Sep 9;(9):CD008638. doi: 10.1002/14651858.CD008638.pub2. Review.


Severe and early quadriceps weakness in mechanically ventilated patients.

Vivodtzev I, Devost AA, Saey D, Villeneuve S, Boilard G, Gagnon P, Provencher S, Simon M, Baillot R, Maltais F, Lellouche F.

Crit Care. 2014 May 23;18(3):431. doi: 10.1186/cc13888. No abstract available.


Mechanical ventilation with high tidal volume and associated mortality in the cardiac intensive care unit.

Shorofsky M, Jayaraman D, Lellouche F, Husa R, Lipes J.

Acute Card Care. 2014 Mar;16(1):9-14. doi: 10.3109/17482941.2013.869345.


Automated weaning and spontaneous breathing trial systems versus non-automated weaning strategies for discontinuation time in invasively ventilated postoperative adults.

Burns KE, Lellouche F, Lessard MR, Friedrich JO.

Cochrane Database Syst Rev. 2014 Feb 13;(2):CD008639. doi: 10.1002/14651858.CD008639.pub2. Review.


Impact of the humidification device on intubation rate during noninvasive ventilation with ICU ventilators: results of a multicenter randomized controlled trial.

Lellouche F, L'Her E, Abroug F, Deye N, Rodriguez PO, Rabbat A, Jaber S, Fartoukh M, Conti G, Cracco C, Richard JC, Ricard JD, Mal H, Mentec H, Loisel F, Lacherade JC, Taillé S, Brochard L.

Intensive Care Med. 2014 Feb;40(2):211-9. doi: 10.1007/s00134-013-3145-z. Epub 2013 Nov 26.


Comparison of usual and alternative methods to measure height in mechanically ventilated patients: potential impact on protective ventilation.

Bojmehrani A, Bergeron-Duchesne M, Bouchard C, Simard S, Bouchard PA, Vanderschuren A, L'Her E, Lellouche F.

Respir Care. 2014 Jul;59(7):1025-33. doi: 10.4187/respcare.02732. Epub 2013 Nov 19.


Mechanical ventilation system monitoring: automatic detection of dynamic hyperinflation and asynchrony.

Nguyen QT, Pastor D, Lellouche F, L'her E.

Conf Proc IEEE Eng Med Biol Soc. 2013;2013:5207-10. doi: 10.1109/EMBC.2013.6610722.


Influence of ambient temperature and minute ventilation on passive and active heat and moisture exchangers.

Lellouche F, Qader S, Taillé S, Lyazidi A, Brochard L.

Respir Care. 2014 May;59(5):637-43. doi: 10.4187/respcare.02523. Epub 2013 Oct 8.


Assessment of humidification performance: still no easy method!

Cuquemelle E, Lellouche F.

Respir Care. 2013 Sep;58(9):1559-61. doi: 10.4187/respcare.02761. No abstract available.


The authors respond.

Lellouche F, Brochard L.

Respir Care. 2013 Mar;58(3):e36-8. No abstract available.

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