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Items: 1 to 50 of 181

1.

3D bioprinting of liver spheroids derived from human induced pluripotent stem cells sustain liver function and viability in vitro.

Goulart E, de Caires-Junior LC, Telles-Silva KA, Araujo BHS, Rocco SA, Sforca M, de Sousa IL, Kobayashi GS, Musso CM, Assoni AF, Oliveira D, Caldini E, Raia S, Lelkes PI, Zatz M.

Biofabrication. 2019 Nov 27;12(1):015010. doi: 10.1088/1758-5090/ab4a30.

PMID:
31577996
2.

Cell-Based Adhesion Assays for Isolation of Snake Venom's Integrin Antagonists.

Lazarovici P, Marcinkiewicz C, Lelkes PI.

Methods Mol Biol. 2020;2068:205-223. doi: 10.1007/978-1-4939-9845-6_11.

PMID:
31576530
3.

Biocompatibility studies of fluorescent diamond particles-(NV)~800nm (part V): in vitro kinetics and in vivo localization in rat liver following long-term exposure.

Gerstenhaber JA, Marcinkiewicz C, Barone FC, Sternberg M, D'Andrea MR, Lelkes PI, Feuerstein GZ.

Int J Nanomedicine. 2019 Aug 12;14:6451-6464. doi: 10.2147/IJN.S209663. eCollection 2019.

4.

Topographic cues of a novel bilayered scaffold modulate dental pulp stem cells differentiation by regulating YAP signalling through cytoskeleton adjustments.

Du Y, Montoya C, Orrego S, Wei X, Ling J, Lelkes PI, Yang M.

Cell Prolif. 2019 Nov;52(6):e12676. doi: 10.1111/cpr.12676. Epub 2019 Aug 19.

PMID:
31424140
5.

Adult and iPS-derived non-parenchymal cells regulate liver organoid development through differential modulation of Wnt and TGF-β.

Goulart E, de Caires-Junior LC, Telles-Silva KA, Araujo BHS, Kobayashi GS, Musso CM, Assoni AF, Oliveira D, Caldini E, Gerstenhaber JA, Raia S, Lelkes PI, Zatz M.

Stem Cell Res Ther. 2019 Aug 15;10(1):258. doi: 10.1186/s13287-019-1367-x.

6.

An Air Bubble-Isolating Rotating Wall Vessel Bioreactor for Improved Spheroid/Organoid Formation.

Phelan MA, Gianforcaro AL, Gerstenhaber JA, Lelkes PI.

Tissue Eng Part C Methods. 2019 Aug;25(8):479-488. doi: 10.1089/ten.TEC.2019.0088.

PMID:
31328683
7.

From Snake Venom's Disintegrins and C-Type Lectins to Anti-Platelet Drugs.

Lazarovici P, Marcinkiewicz C, Lelkes PI.

Toxins (Basel). 2019 May 27;11(5). pii: E303. doi: 10.3390/toxins11050303. Review.

8.

Long-term biocompatibility of fluorescent diamonds-(NV)-Z~800 nm in rats: survival, morbidity, histopathology, particle distribution and excretion studies (part IV).

Barone FC, Marcinkiewicz C, Li J, Feng Y, Sternberg M, Lelkes PI, Rosenbaum-Halevi D, Gerstenhaber JA, Feuerstein GZ.

Int J Nanomedicine. 2019 Feb 14;14:1163-1175. doi: 10.2147/IJN.S189048. eCollection 2019.

9.

Mini and customized low-cost bioreactors for optimized high-throughput generation of tissue organoids.

Phelan MA, Lelkes PI, Swaroop A.

Stem Cell Investig. 2018 Oct 10;5:33. doi: 10.21037/sci.2018.09.06. eCollection 2018. No abstract available.

10.

Rigidity controls human desmoplastic matrix anisotropy to enable pancreatic cancer cell spread via extracellular signal-regulated kinase 2.

Malik R, Luong T, Cao X, Han B, Shah N, Franco-Barraza J, Han L, Shenoy VB, Lelkes PI, Cukierman E.

Matrix Biol. 2019 Aug;81:50-69. doi: 10.1016/j.matbio.2018.11.001. Epub 2018 Nov 7.

PMID:
30412725
11.

Pilot study on biocompatibility of fluorescent nanodiamond-(NV)-Z~800 particles in rats: safety, pharmacokinetics, and bio-distribution (part III).

Barone FC, Marcinkiewicz C, Li J, Sternberg M, Lelkes PI, Dikin DA, Bergold PJ, Gerstenhaber JA, Feuerstein G.

Int J Nanomedicine. 2018 Sep 17;13:5449-5468. doi: 10.2147/IJN.S171117. eCollection 2018.

12.

Gradient porous fibrous scaffolds: a novel approach to improving cell penetration in electrospun scaffolds.

Timnak A, Gerstenhaber JA, Dong K, Har-El YE, Lelkes PI.

Biomed Mater. 2018 Sep 21;13(6):065010. doi: 10.1088/1748-605X/aadbbe.

PMID:
30129563
13.

New Approaches to Respiratory Assist: Bioengineering an Ambulatory, Miniaturized Bioartificial Lung.

Novosel E, Borchers K, Kluger PJ, Mantalaris A, Matheis G, Pistolesi M, Schneider J, Wenz A, Lelkes PI.

ASAIO J. 2019 Jul;65(5):422-429. doi: 10.1097/MAT.0000000000000841.

PMID:
30044238
14.

A Bilayered Poly (Lactic-Co-Glycolic Acid) Scaffold Provides Differential Cues for the Differentiation of Dental Pulp Stem Cells.

Gangolli RA, Devlin SM, Gerstenhaber JA, Lelkes PI, Yang M.

Tissue Eng Part A. 2019 Feb;25(3-4):224-233. doi: 10.1089/ten.TEA.2018.0041. Epub 2018 Sep 13.

PMID:
29984629
15.

Nerve Growth Factor-Induced Angiogenesis: 2. The Quail Chorioallantoic Membrane Assay.

Lazarovici P, Lahiani A, Gincberg G, Haham D, Marcinkiewicz C, Lelkes PI.

Methods Mol Biol. 2018;1727:251-259. doi: 10.1007/978-1-4939-7571-6_19.

PMID:
29222787
16.

Nerve Growth Factor-Induced Angiogenesis: 1. Endothelial Cell Tube Formation Assay.

Lazarovici P, Lahiani A, Gincberg G, Haham D, Fluksman A, Benny O, Marcinkiewicz C, Lelkes PI.

Methods Mol Biol. 2018;1727:239-250. doi: 10.1007/978-1-4939-7571-6_18.

PMID:
29222786
17.

Vascular thrombus imaging in vivo via near-infrared fluorescent nanodiamond particles bioengineered with the disintegrin bitistatin (Part II).

Gerstenhaber JA, Barone FC, Marcinkiewicz C, Li J, Shiloh AO, Sternberg M, Lelkes PI, Feuerstein G.

Int J Nanomedicine. 2017 Nov 24;12:8471-8482. doi: 10.2147/IJN.S146946. eCollection 2017.

18.

Bitistatin-functionalized fluorescent nanodiamond particles specifically bind to purified human platelet integrin receptor αIIbβ3 and activated platelets.

Marcinkiewicz C, Gerstenhaber JA, Sternberg M, Lelkes PI, Feuerstein G.

Int J Nanomedicine. 2017 May 15;12:3711-3720. doi: 10.2147/IJN.S134128. eCollection 2017.

19.

In Vivo Testing of Extracorporeal Membrane Ventilators: iLA-Activve Versus Prototype I-Lung.

Kischkel S, Bergt S, Brock B, von Grönheim J, Herbst A, Epping MJ, Matheis G, Novosel E, Schneider J, Warnke P, Podbielski A, Roesner JP, Lelkes PI, Vollmar B.

ASAIO J. 2017 Mar/Apr;63(2):185-192. doi: 10.1097/MAT.0000000000000465.

PMID:
28092273
20.

Near infrared spectroscopic imaging assessment of cartilage composition: Validation with mid infrared imaging spectroscopy.

Palukuru UP, Hanifi A, McGoverin CM, Devlin S, Lelkes PI, Pleshko N.

Anal Chim Acta. 2016 Jul 5;926:79-87. doi: 10.1016/j.aca.2016.04.031. Epub 2016 Apr 25.

21.

Enhanced Re-Endothelialization of Decellularized Rat Lungs.

Stabler CT, Caires LC Jr, Mondrinos MJ, Marcinkiewicz C, Lazarovici P, Wolfson MR, Lelkes PI.

Tissue Eng Part C Methods. 2016 May;22(5):439-50. doi: 10.1089/ten.TEC.2016.0012. Epub 2016 Apr 1.

22.

Revascularization of decellularized lung scaffolds: principles and progress.

Stabler CT, Lecht S, Mondrinos MJ, Goulart E, Lazarovici P, Lelkes PI.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 1;309(11):L1273-85. doi: 10.1152/ajplung.00237.2015. Epub 2015 Sep 25. Review.

23.

Mesenchymal stem cells for therapeutic applications in pulmonary medicine.

Stabler CT, Lecht S, Lazarovici P, Lelkes PI.

Br Med Bull. 2015 Sep;115(1):45-56. doi: 10.1093/bmb/ldv026. Epub 2015 Jun 10. Review.

PMID:
26063231
24.

An official American Thoracic Society workshop report: stem cells and cell therapies in lung biology and diseases.

Weiss DJ, Chambers D, Giangreco A, Keating A, Kotton D, Lelkes PI, Wagner DE, Prockop DJ; ATS Subcommittee on Stem Cells and Cell Therapies.

Ann Am Thorac Soc. 2015 Apr;12(4):S79-97. doi: 10.1513/AnnalsATS.201502-086ST.

25.

Association of p75(NTR) and α9β1 integrin modulates NGF-dependent cellular responses.

Ventresca EM, Lecht S, Jakubowski P, Chiaverelli RA, Weaver M, Del Valle L, Ettinger K, Gincberg G, Priel A, Braiman A, Lazarovici P, Lelkes PI, Marcinkiewicz C.

Cell Signal. 2015 Jun;27(6):1225-36. doi: 10.1016/j.cellsig.2015.02.029. Epub 2015 Mar 5.

26.

Biomechanical and biochemical remodeling of stromal extracellular matrix in cancer.

Malik R, Lelkes PI, Cukierman E.

Trends Biotechnol. 2015 Apr;33(4):230-6. doi: 10.1016/j.tibtech.2015.01.004. Epub 2015 Feb 20. Review.

27.

Anti-angiogenic activities of snake venom CRISP isolated from Echis carinatus sochureki.

Lecht S, Chiaverelli RA, Gerstenhaber J, Calvete JJ, Lazarovici P, Casewell NR, Harrison R, Lelkes PI, Marcinkiewicz C.

Biochim Biophys Acta. 2015 Jun;1850(6):1169-79. doi: 10.1016/j.bbagen.2015.02.002. Epub 2015 Feb 7.

PMID:
25665484
28.

Osseointegrative properties of electrospun hydroxyapatite-containing nanofibrous chitosan scaffolds.

Frohbergh ME, Katsman A, Mondrinos MJ, Stabler CT, Hankenson KD, Oristaglio JT, Lelkes PI.

Tissue Eng Part A. 2015 Mar;21(5-6):970-81. doi: 10.1089/ten.TEA.2013.0789. Epub 2014 Dec 16.

29.

Hypoxia enhances differentiation of mouse embryonic stem cells into definitive endoderm and distal lung cells.

Pimton P, Lecht S, Stabler CT, Johannes G, Schulman ES, Lelkes PI.

Stem Cells Dev. 2015 Mar 1;24(5):663-76. doi: 10.1089/scd.2014.0343. Epub 2014 Oct 27.

30.

Transcriptional down-regulation of epidermal growth factor (EGF) receptors by nerve growth factor (NGF) in PC12 cells.

Cohen G, Ettinger K, Lecht S, Lelkes PI, Lazarovici P.

J Mol Neurosci. 2014 Nov;54(3):574-85. doi: 10.1007/s12031-014-0388-2. Epub 2014 Jul 31. Review.

PMID:
25078264
31.

Textile-templated electrospun anisotropic scaffolds for regenerative cardiac tissue engineering.

Şenel Ayaz HG, Perets A, Ayaz H, Gilroy KD, Govindaraj M, Brookstein D, Lelkes PI.

Biomaterials. 2014 Oct;35(30):8540-52. doi: 10.1016/j.biomaterials.2014.06.029. Epub 2014 Jul 10.

PMID:
25017096
32.

Engineering de novo assembly of fetal pulmonary organoids.

Mondrinos MJ, Jones PL, Finck CM, Lelkes PI.

Tissue Eng Part A. 2014 Nov;20(21-22):2892-907. doi: 10.1089/ten.TEA.2014.0085. Epub 2014 Jun 25.

33.

Heterogeneous mixed-lineage differentiation of mouse embryonic stem cells induced by conditioned media from a549 cells.

Lecht S, Gerstenhaber JA, Stabler CT, Pimton P, Karamil S, Marcinkiewicz C, Schulman ES, Lelkes PI.

Stem Cells Dev. 2014 Aug 15;23(16):1923-36. doi: 10.1089/scd.2014.0042. Epub 2014 Jun 3.

PMID:
24720740
34.

Neurotherapeutic effect of cord blood derived CD45+ hematopoietic cells in mice after traumatic brain injury.

Arien-Zakay H, Gincberg G, Nagler A, Cohen G, Liraz-Zaltsman S, Trembovler V, Alexandrovich AG, Matok I, Galski H, Elchalal U, Lelkes PI, Lazarovici P, Shohami E.

J Neurotrauma. 2014 Aug 15;31(16):1405-16. doi: 10.1089/neu.2013.3270. Epub 2014 Jul 14.

35.

Cytocompatibility of novel extracellular matrix protein analogs of biodegradable polyester polymers derived from α-hydroxy amino acids.

Lecht S, Cohen-Arazi N, Cohen G, Ettinger K, Momic T, Kolitz M, Naamneh M, Katzhendler J, Domb AJ, Lazarovici P, Lelkes PI.

J Biomater Sci Polym Ed. 2014;25(6):608-24. doi: 10.1080/09205063.2014.888303. Epub 2014 Feb 25.

PMID:
24568316
36.

Enhanced reseeding of decellularized rodent lungs with mouse embryonic stem cells.

Lecht S, Stabler CT, Rylander AL, Chiaverelli R, Schulman ES, Marcinkiewicz C, Lelkes PI.

Biomaterials. 2014 Mar;35(10):3252-62. doi: 10.1016/j.biomaterials.2013.12.093. Epub 2014 Jan 15.

37.

Mechanical study of polycaprolactone-hydroxyapatite porous scaffolds created by porogen-based solid freeform fabrication method.

Lu L, Zhang Q, Wootton DM, Chiou R, Li D, Lu B, Lelkes PI, Zhou J.

J Appl Biomater Funct Mater. 2014 Dec 30;12(3):145-54. doi: 10.5301/JABFM.5000163.

PMID:
24425377
38.

NGF promotes hemodynamic recovery in a rabbit hindlimb ischemic model through trkA- and VEGFR2-dependent pathways.

Karatzas A, Katsanos K, Lilis I, Papadaki H, Kitrou P, Lecht S, Marcinkiewicz C, Siablis D, Lelkes PI, Lazarovici P, Tsopanoglou NE.

J Cardiovasc Pharmacol. 2013 Sep;62(3):270-7. doi: 10.1097/FJC.0b013e3182982de7.

PMID:
23644989
39.

Electrospun rapamycin-eluting polyurethane fibers for vascular grafts.

Han J, Farah S, Domb AJ, Lelkes PI.

Pharm Res. 2013 Jul;30(7):1735-48. doi: 10.1007/s11095-013-1016-5. Epub 2013 Apr 9.

PMID:
23568519
40.

Tissue factor activity and ECM-related gene expression in human aortic endothelial cells grown on electrospun biohybrid scaffolds.

Han J, Gerstenhaber JA, Lazarovici P, Lelkes PI.

Biomacromolecules. 2013 May 13;14(5):1338-48. doi: 10.1021/bm400450m. Epub 2013 Apr 18.

PMID:
23560456
41.

ERK2-regulated TIMP1 induces hyperproliferation of K-Ras(G12D)-transformed pancreatic ductal cells.

Botta GP, Reichert M, Reginato MJ, Heeg S, Rustgi AK, Lelkes PI.

Neoplasia. 2013 Apr;15(4):359-72.

42.

ErbB2, FoxM1 and 14-3-3ζ prime breast cancer cells for invasion in response to ionizing radiation.

Kambach DM, Sodi VL, Lelkes PI, Azizkhan-Clifford J, Reginato MJ.

Oncogene. 2014 Jan 30;33(5):589-98. doi: 10.1038/onc.2012.629. Epub 2013 Jan 14.

43.

Enhanced survival and neurite network formation of human umbilical cord blood neuronal progenitors in three-dimensional collagen constructs.

Bercu MM, Arien-Zakay H, Stoler D, Lecht S, Lelkes PI, Samuel S, Or R, Nagler A, Lazarovici P, Elchalal U.

J Mol Neurosci. 2013 Oct;51(2):249-61. doi: 10.1007/s12031-012-9933-z. Epub 2012 Dec 12.

PMID:
23233347
44.

Electrospun hydroxyapatite-containing chitosan nanofibers crosslinked with genipin for bone tissue engineering.

Frohbergh ME, Katsman A, Botta GP, Lazarovici P, Schauer CL, Wegst UG, Lelkes PI.

Biomaterials. 2012 Dec;33(36):9167-78. doi: 10.1016/j.biomaterials.2012.09.009. Epub 2012 Sep 27.

45.

Neural stem cells: therapeutic potential for neurodegenerative diseases.

Gincberg G, Arien-Zakay H, Lazarovici P, Lelkes PI.

Br Med Bull. 2012;104:7-19. doi: 10.1093/bmb/lds024. Epub 2012 Sep 17. Review.

PMID:
22988303
46.

Angioneural crosstalk in scaffolds with oriented microchannels for regenerative spinal cord injury repair.

Saglam A, Perets A, Canver AC, Li HL, Kollins K, Cohen G, Fischer I, Lazarovici P, Lelkes PI.

J Mol Neurosci. 2013 Feb;49(2):334-46. doi: 10.1007/s12031-012-9863-9. Epub 2012 Aug 10.

PMID:
22878912
47.

Neuroprotective effects of nimodipine and nifedipine in the NGF-differentiated PC12 cells exposed to oxygen-glucose deprivation or trophic withdrawal.

Lecht S, Rotfeld E, Arien-Zakay H, Tabakman R, Matzner H, Yaka R, Lelkes PI, Lazarovici P.

Int J Dev Neurosci. 2012 Oct;30(6):465-9. doi: 10.1016/j.ijdevneu.2012.05.007. Epub 2012 Jun 5.

PMID:
22677442
48.

Alimentary 'green' proteins as electrospun scaffolds for skin regenerative engineering.

Lin L, Perets A, Har-el YE, Varma D, Li M, Lazarovici P, Woerdeman DL, Lelkes PI.

J Tissue Eng Regen Med. 2013 Dec;7(12):994-1008. doi: 10.1002/term.1493. Epub 2012 Apr 12.

PMID:
22499248
49.

Mechanical properties and biomineralization of multifunctional nanodiamond-PLLA composites for bone tissue engineering.

Zhang Q, Mochalin VN, Neitzel I, Hazeli K, Niu J, Kontsos A, Zhou JG, Lelkes PI, Gogotsi Y.

Biomaterials. 2012 Jul;33(20):5067-75. doi: 10.1016/j.biomaterials.2012.03.063. Epub 2012 Apr 9.

PMID:
22494891
50.

Constitutive K-RasG12D activation of ERK2 specifically regulates 3D invasion of human pancreatic cancer cells via MMP-1.

Botta GP, Reginato MJ, Reichert M, Rustgi AK, Lelkes PI.

Mol Cancer Res. 2012 Feb;10(2):183-96. doi: 10.1158/1541-7786.MCR-11-0399. Epub 2011 Dec 8.

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