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Items: 1 to 50 of 66

1.

Can dual-energy computed tomography improve visualization of hypoenhancing liver lesions in portal venous phase? Assessment of advanced image-based virtual monoenergetic images.

Caruso D, De Cecco CN, Schoepf UJ, Schaefer AR, Leland PW, Johnson D, Laghi A, Hardie AD.

Clin Imaging. 2017 Jan - Feb;41:118-124. doi: 10.1016/j.clinimag.2016.10.015. Epub 2016 Oct 19.

PMID:
27840263
2.

Characterization of the Enzymatic Activity of SETDB1 and Its 1:1 Complex with ATF7IP.

Basavapathruni A, Gureasko J, Porter Scott M, Hermans W, Godbole A, Leland PA, Boriack-Sjodin PA, Wigle TJ, Copeland RA, Riera TV.

Biochemistry. 2016 Mar 22;55(11):1645-51. doi: 10.1021/acs.biochem.5b01202. Epub 2016 Feb 11.

PMID:
26813693
3.

Identification, characterization, and targeting of IL-4 receptor by IL-4-Pseudomonas exotoxin in mouse models of anaplastic thyroid cancer.

Joshi BH, Suzuki A, Fujisawa T, Leland P, Varrichio F, Lababidi S, Lloyd R, Kasperbauer J, Puri RK.

Discov Med. 2015 Nov;20(111):273-84.

4.

Targeting of IL-4 and IL-13 receptors for cancer therapy.

Suzuki A, Leland P, Joshi BH, Puri RK.

Cytokine. 2015 Sep;75(1):79-88. doi: 10.1016/j.cyto.2015.05.026. Epub 2015 Jun 15. Review.

PMID:
26088753
5.

Interleukin-4 receptor alpha overexpression in human bladder cancer correlates with the pathological grade and stage of the disease.

Joshi BH, Leland P, Lababidi S, Varrichio F, Puri RK.

Cancer Med. 2014 Dec;3(6):1615-28. doi: 10.1002/cam4.330. Epub 2014 Sep 10.

6.

Analysis of biodistribution of intracranially infused radiolabeled interleukin-13 receptor-targeted immunotoxin IL-13PE by SPECT/CT in an orthotopic mouse model of human glioma.

Suzuki A, Leland P, Kobayashi H, Choyke PL, Jagoda EM, Inoue T, Joshi BH, Puri RK.

J Nucl Med. 2014 Aug;55(8):1323-9. doi: 10.2967/jnumed.114.138404. Epub 2014 Jun 19.

7.

IL-13Rα2-bearing, type II NKT cells reactive to sulfatide self-antigen populate the mucosa of ulcerative colitis.

Fuss IJ, Joshi B, Yang Z, Degheidy H, Fichtner-Feigl S, de Souza H, Rieder F, Scaldaferri F, Schirbel A, Scarpa M, West G, Yi C, Xu L, Leland P, Yao M, Mannon P, Puri RK, Fiocchi C, Strober W.

Gut. 2014 Nov;63(11):1728-36. doi: 10.1136/gutjnl-2013-305671. Epub 2014 Feb 10.

8.

Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma.

Kunwar S, Chang S, Westphal M, Vogelbaum M, Sampson J, Barnett G, Shaffrey M, Ram Z, Piepmeier J, Prados M, Croteau D, Pedain C, Leland P, Husain SR, Joshi BH, Puri RK; PRECISE Study Group.

Neuro Oncol. 2010 Aug;12(8):871-81. doi: 10.1093/neuonc/nop054. Epub 2010 Feb 4.

9.

Overexpression of interleukin-13 receptor-alpha2 in neuroendocrine malignant pheochromocytoma: a novel target for receptor directed anti-cancer therapy.

Lai EW, Joshi BH, Martiniova L, Dogra R, Fujisawa T, Leland P, de Krijger RR, Lubensky IA, Elkahloun AG, Morris JC, Puri RK, Pacak K.

J Clin Endocrinol Metab. 2009 Aug;94(8):2952-7. doi: 10.1210/jc.2009-0309. Epub 2009 Jun 2.

10.

Ribonuclease inhibitor regulates neovascularization by human angiogenin.

Dickson KA, Kang DK, Kwon YS, Kim JC, Leland PA, Kim BM, Chang SI, Raines RT.

Biochemistry. 2009 May 12;48(18):3804-6. doi: 10.1021/bi9005094.

11.
12.

Identification of interleukin-13 receptor alpha2 chain overexpression in situ in high-grade diffusely infiltrative pediatric brainstem glioma.

Joshi BH, Puri RA, Leland P, Varricchio F, Gupta G, Kocak M, Gilbertson RJ, Puri RK; US Pediatric Brain Tumor Consortium.

Neuro Oncol. 2008 Jun;10(3):265-74. doi: 10.1215/15228517-2007-066. Epub 2008 Apr 22.

13.

A recombinant IL-4-Pseudomonas exotoxin inhibits protein synthesis and overcomes apoptosis resistance in human CLL B cells.

Kay NE, Bone ND, Lee YK, Jelinek DF, Leland P, Battle TE, Frank DA, Puri RK.

Leuk Res. 2005 Sep;29(9):1009-18. Epub 2005 Apr 12.

PMID:
16038727
14.

Hodgkin lymphoma therapy with interleukin-4 receptor-directed cytotoxin in an infiltrating animal model.

Kawakami M, Kawakami K, Kioi M, Leland P, Puri RK.

Blood. 2005 May 1;105(9):3707-13. Epub 2004 Dec 30.

15.

Gene expression profiling identifies IL-13 receptor alpha 2 chain as a therapeutic target in prostate tumor cells overexpressing adrenomedullin.

Gonzalez-Moreno O, Calvo A, Joshi BH, Abasolo I, Leland P, Wang Z, Montuenga L, Puri RK, Green JE.

Int J Cancer. 2005 May 10;114(6):870-8.

16.

Interleukin-4 receptor cytotoxin as therapy for human malignant pleural mesothelioma xenografts.

Beseth BD, Cameron RB, Leland P, You L, Varricchio F, Kreitman RJ, Maki RA, Jablons DM, Husain SR, Puri RK.

Ann Thorac Surg. 2004 Aug;78(2):436-43; discussion 436-43.

PMID:
15276492
18.

X-ray structure of two crystalline forms of a streptomycete ribonuclease with cytotoxic activity.

Sevcik J, Urbanikova L, Leland PA, Raines RT.

J Biol Chem. 2002 Dec 6;277(49):47325-30. Epub 2002 Sep 11.

20.

Mutation and functional analysis of IL-13 receptors in human malignant glioma cells.

Kawakami M, Leland P, Kawakami K, Puri RK.

Oncol Res. 2001;12(11-12):459-67.

PMID:
11939409
21.

IL-4 receptors on human medulloblastoma tumours serve as a sensitive target for a circular permuted IL-4-Pseudomonas exotoxin fusion protein.

Joshi BH, Leland P, Silber J, Kreitman RJ, Pastan I, Berger M, Puri RK.

Br J Cancer. 2002 Jan 21;86(2):285-91.

22.

The ribonucleolytic activity of angiogenin.

Leland PA, Staniszewski KE, Park C, Kelemen BR, Raines RT.

Biochemistry. 2002 Jan 29;41(4):1343-50.

PMID:
11802736
24.
25.

Endowing human pancreatic ribonuclease with toxicity for cancer cells.

Leland PA, Staniszewski KE, Kim BM, Raines RT.

J Biol Chem. 2001 Nov 16;276(46):43095-102. Epub 2001 Sep 12.

26.

Cancer chemotherapy--ribonucleases to the rescue.

Leland PA, Raines RT.

Chem Biol. 2001 May;8(5):405-13. Review.

28.
29.
30.

Hypersensitive substrate for ribonucleases.

Kelemen BR, Klink TA, Behlke MA, Eubanks SR, Leland PA, Raines RT.

Nucleic Acids Res. 1999 Sep 15;27(18):3696-701.

31.

Ribonuclease A variants with potent cytotoxic activity.

Leland PA, Schultz LW, Kim BM, Raines RT.

Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10407-12.

32.

Ribonucleases endowed with specific toxicity for spermatogenic layers.

Matoušek J, Kim JS, Souček J, Rìha J, Ribó M, Leland PA, Raines RT.

Comp Biochem Physiol B Biochem Mol Biol. 1997 Dec;118(4):881-888.

33.

Interleukin-13 receptors on human prostate carcinoma cell lines represent a novel target for a chimeric protein composed of IL-13 and a mutated form of Pseudomonas exotoxin.

Maini A, Hillman G, Haas GP, Wang CY, Montecillo E, Hamzavi F, Pontes JE, Leland P, Pastan I, Debinski W, Puri RK.

J Urol. 1997 Sep;158(3 Pt 1):948-53.

PMID:
9258124
34.

The IL-13 receptor structure differs on various cell types and may share more than one component with IL-4 receptor.

Obiri NI, Leland P, Murata T, Debinski W, Puri RK.

J Immunol. 1997 Jan 15;158(2):756-64.

PMID:
8992992
35.

Interleukin-4 receptor expression in vivo on human AIDS-related Kaposi's sarcoma.

Varricchio F, Husain SR, Leland P, Gill P, Puri RK.

Oncol Res. 1997;9(9):495-503.

PMID:
9495455
36.
37.

Transcriptional up-regulation of interleukin 4 receptors by human immunodeficiency virus type 1 tat gene.

Husain SR, Leland P, Aggarwal BB, Puri RK.

AIDS Res Hum Retroviruses. 1996 Sep 20;12(14):1349-59.

PMID:
8891114
38.

Receptor for interleukin (IL) 13 does not interact with IL4 but receptor for IL4 interacts with IL13 on human glioma cells.

Debinski W, Miner R, Leland P, Obiri NI, Puri RK.

J Biol Chem. 1996 Sep 13;271(37):22428-33.

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A chimeric protein comprised of IL-4 and Pseudomonas exotoxin is cytotoxic for activated human lymphocytes.

Puri RK, Mehrotra PT, Leland P, Kreitman RJ, Siegel JP, Pastan I.

J Immunol. 1994 Apr 1;152(7):3693-700.

PMID:
8144944
46.

Tumor necrosis factor upregulates interleukin-4 receptors on murine sarcoma cells.

Puri RK, Leland P.

Biochem Biophys Res Commun. 1993 Dec 30;197(3):1424-30.

PMID:
8280160
47.

Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor.

Russell SM, Keegan AD, Harada N, Nakamura Y, Noguchi M, Leland P, Friedmann MC, Miyajima A, Puri RK, Paul WE, et al.

Science. 1993 Dec 17;262(5141):1880-3.

PMID:
8266078
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