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Items: 40


Timeliness of Childhood Vaccination Coverage: the Growing Up in Singapore Towards Healthy Outcomes Study.

Loy SL, Cheung YB, Chan JKY, Soh SE, Godfrey KM, Tan KH, Shek LP, Chong YS, Lek N, Yap F, Teoh OH, Yung CF, Thoon KC.

Prev Sci. 2020 Jan 20. doi: 10.1007/s11121-019-01078-2. [Epub ahead of print]


Associations of Circadian Eating Pattern and Diet Quality with Substantial Postpartum Weight Retention.

Loy SL, Cheung YB, Colega MT, Chia A, Han CY, Godfrey KM, Chong YS, Shek LP, Tan KH, Lek N, Chan JKY, Chong MF, Yap F.

Nutrients. 2019 Nov 6;11(11). pii: E2686. doi: 10.3390/nu11112686.


Maternal night-eating pattern and glucose tolerance during pregnancy: study protocol for a longitudinal study.

Loy SL, Cheung YB, Chong M, Müller-Riemenschneider F, Lek N, Lee YS, Tan KH, Chern B, Yap F, Chan J.

BMJ Open. 2019 Oct 10;9(10):e030036. doi: 10.1136/bmjopen-2019-030036.


What are the appropriate reference limits for the diagnosis of hypophosphataemia in paediatric patients?

Tan JG, Vasanwala RF, Yap F, Lek N, Ho CKM.

J Clin Pathol. 2019 Aug;72(8):569-572. doi: 10.1136/jclinpath-2019-205736. Epub 2019 Apr 17. No abstract available.


Association of Elective and Emergency Cesarean Delivery With Early Childhood Overweight at 12 Months of Age.

Cai M, Loy SL, Tan KH, Godfrey KM, Gluckman PD, Chong YS, Shek LP, Cheung YB, Lek N, Lee YS, Chan SY, Chan JKY, Yap F, Ang SB.

JAMA Netw Open. 2018 Nov 2;1(7):e185025. doi: 10.1001/jamanetworkopen.2018.5025.


Long-term Healthcare of People with Disorders of Sex Development: Predictors of Pubertal Outcomes of Partial Androgen Insensitivity Syndrome - Authors' Reply.

Lek N, Tadokoro-Cuccaro R, Hughes I.

EBioMedicine. 2018 Nov;37:31. doi: 10.1016/j.ebiom.2018.10.035. Epub 2018 Oct 29. No abstract available.


Predicting puberty in partial androgen insensitivity syndrome: Use of clinical and functional androgen receptor indices.

Lek N, Tadokoro-Cuccaro R, Whitchurch JB, Mazumder B, Miles H, Prentice P, Bunch T, Zielińska K, Metzler V, Mongan NP, Heery DM, Hughes IA.

EBioMedicine. 2018 Oct;36:401-409. doi: 10.1016/j.ebiom.2018.09.047. Epub 2018 Oct 11.


Female adiposity and time-to-pregnancy: a multiethnic prospective cohort.

Loy SL, Cheung YB, Soh SE, Ng S, Tint MT, Aris IM, Bernard JY, Chong YS, Godfrey KM, Shek LP, Tan KH, Lee YS, Tan HH, Chern BSM, Lek N, Yap F, Chan SY, Chi C, Chan JKY.

Hum Reprod. 2018 Nov 1;33(11):2141-2149. doi: 10.1093/humrep/dey300.


High Maternal Circulating Cotinine During Pregnancy is Associated With Persistently Shorter Stature From Birth to Five Years in an Asian Cohort.

Ng S, Aris IM, Tint MT, Gluckman PD, Godfrey KM, Shek LP, Yap F, Tan KH, Lek N, Teoh OH, Chan YH, Chong MF, Lee YS, Chong YS, Kramer MS, Chan SY.

Nicotine Tob Res. 2019 Jul 17;21(8):1103-1112. doi: 10.1093/ntr/nty148.


Circadian feeding patterns of 12-month-old infants.

Wee PH, Loy SL, Toh JY, Tham EKH, Cheung YB, Godfrey KM, Gluckman PD, Saw SM, Chong YS, Lek N, Chan JKY, Goh DYT, Chong MF, Yap F.

Br J Nutr. 2017 Jun;117(12):1702-1710. doi: 10.1017/S0007114517001684.


Short-term poor glycemic control and retinal microvascular changes in pediatric Type 1 Diabetes patients in Singapore: a pilot study.

Li LJ, Lamoureux E, Wong TY, Lek N.

BMC Ophthalmol. 2017 Jun 15;17(1):60. doi: 10.1186/s12886-017-0449-8.


Maternal Night-Fasting Interval during Pregnancy Is Directly Associated with Neonatal Head Circumference and Adiposity in Girls but Not Boys.

Loy SL, Wee PH, Colega MT, Cheung YB, Aris IM, Chan JKY, Godfrey KM, Gluckman PD, Tan KH, Shek LP, Chong YS, Natarajan P, Müller-Riemenschneider F, Lek N, Rajadurai VS, Tint MT, Lee YS, Chong MF, Yap F.

J Nutr. 2017 Jul;147(7):1384-1391. doi: 10.3945/jn.117.250639. Epub 2017 Jun 7.


Dominant ER Stress-Inducing WFS1 Mutations Underlie a Genetic Syndrome of Neonatal/Infancy-Onset Diabetes, Congenital Sensorineural Deafness, and Congenital Cataracts.

De Franco E, Flanagan SE, Yagi T, Abreu D, Mahadevan J, Johnson MB, Jones G, Acosta F, Mulaudzi M, Lek N, Oh V, Petz O, Caswell R, Ellard S, Urano F, Hattersley AT.

Diabetes. 2017 Jul;66(7):2044-2053. doi: 10.2337/db16-1296. Epub 2017 May 3.


Plasma Vitamin D Deficiency Is Associated With Poor Sleep Quality and Night-Time Eating at Mid-Pregnancy in Singapore.

Cheng TS, Loy SL, Cheung YB, Cai S, Colega MT, Godfrey KM, Chong YS, Tan KH, Shek LP, Lee YS, Lek N, Chan JK, Chong MF, Yap F.

Nutrients. 2017 Mar 29;9(4). pii: E340. doi: 10.3390/nu9040340.


Plasma ω-3 fatty acids in pregnancy are inversely associated with postpartum weight retention in a multiethnic Asian cohort.

Loy SL, Ng MJH, Cheung YB, Godfrey KM, Calder PC, Lek N, Yap F, Müller-Riemenschneider F, Natarajan P, Chong YS, Tan KH, Shek LP, Chong MF, Chan JKY.

Am J Clin Nutr. 2017 May;105(5):1158-1165. doi: 10.3945/ajcn.116.151258. Epub 2017 Mar 22.


Gestational diabetes mellitus and retinal microvasculature.

Li LJ, Kramer M, Tapp RJ, Man RE, Lek N, Cai S, Yap F, Gluckman P, Tan KH, Chong YS, Koh JY, Saw SM, Cheung YB, Wong TY.

BMC Ophthalmol. 2017 Jan 18;17(1):4. doi: 10.1186/s12886-016-0398-7.


Maternal Circadian Eating Time and Frequency Are Associated with Blood Glucose Concentrations during Pregnancy.

Loy SL, Chan JK, Wee PH, Colega MT, Cheung YB, Godfrey KM, Kwek K, Saw SM, Chong YS, Natarajan P, Müller-Riemenschneider F, Lek N, Chong MF, Yap F.

J Nutr. 2017 Jan;147(1):70-77. doi: 10.3945/jn.116.239392. Epub 2016 Oct 19.


Demographic Characteristics, Health Behaviors Before and During Pregnancy, and Pregnancy and Birth Outcomes in Mothers with Different Pregnancy Planning Status.

Cheng TS, Loy SL, Cheung YB, Godfrey KM, Gluckman PD, Kwek K, Saw SM, Chong YS, Lee YS, Yap F, Yen Chan JK, Lek N.

Prev Sci. 2016 Nov;17(8):960-969. doi: 10.1007/s11121-016-0694-8.


Predominantly nighttime feeding and weight outcomes in infants.

Cheng TS, Loy SL, Toh JY, Cheung YB, Chan JK, Godfrey KM, Gluckman PD, Saw SM, Chong YS, Lee YS, Lek N, Chong MF, Yap F.

Am J Clin Nutr. 2016 Aug;104(2):380-8. doi: 10.3945/ajcn.116.130765. Epub 2016 Jul 6.


Predominantly night-time feeding and maternal glycaemic levels during pregnancy.

Loy SL, Cheng TS, Colega MT, Cheung YB, Godfrey KM, Gluckman PD, Kwek K, Saw SM, Chong YS, Padmapriya N, Müller-Riemenschneider F, Lek N, Yap F, Chong MF, Chan JKY.

Br J Nutr. 2016 May;115(9):1563-1570. doi: 10.1017/S0007114516000441. Epub 2016 Mar 7.


Singaporean Mothers' Perception of Their Three-year-old Child's Weight Status: A Cross-Sectional Study.

Cheng TS, Loy SL, Cheung YB, Chan JK, Tint MT, Godfrey KM, Gluckman PD, Kwek K, Saw SM, Chong YS, Lee YS, Yap F, Lek N; Growing Up in Singapore Towards Healthy Outcomes (GUSTO) study group.

PLoS One. 2016 Jan 28;11(1):e0147563. doi: 10.1371/journal.pone.0147563. eCollection 2016.


Sexually dimorphic response to feeding mode in the growth of infants.

Cheng TS, Loy SL, Cheung YB, Chan JK, Pang WW, Godfrey KM, Gluckman PD, Kwek K, Saw SM, Chong YS, Lee YS, Lek N, Yap F.

Am J Clin Nutr. 2016 Feb;103(2):398-405. doi: 10.3945/ajcn.115.115493. Epub 2015 Dec 30.


MC3R gene polymorphisms are associated with early childhood adiposity gain and infant appetite in an Asian population.

Aris IM, Tint MT, Teh AL, Holbrook JD, Quah PL, Chong MF, Lin X, Soh SE, Saw SM, Kwek K, Godfrey KM, Gluckman PD, Chong YS, Lek N, Yap F, Lee YS.

Pediatr Obes. 2016 Dec;11(6):450-458. doi: 10.1111/ijpo.12086. Epub 2015 Dec 11.


Association of Maternal Vitamin D Status with Glucose Tolerance and Caesarean Section in a Multi-Ethnic Asian Cohort: The Growing Up in Singapore Towards Healthy Outcomes Study.

Loy SL, Lek N, Yap F, Soh SE, Padmapriya N, Tan KH, Biswas A, Yeo GS, Kwek K, Gluckman PD, Godfrey KM, Saw SM, Müller-Riemenschneider F, Chong YS, Chong MF, Chan JK; Growing Up in Singapore Towards Healthy Outcomes (GUSTO) study group.

PLoS One. 2015 Nov 16;10(11):e0142239. doi: 10.1371/journal.pone.0142239. eCollection 2015.


Maternal Blood Pressure During Pregnancy and Early Childhood Blood Pressures in the Offspring: The GUSTO Birth Cohort Study.

Lim WY, Lee YS, Yap FK, Aris IM, Lek N, Meaney M, Gluckman PD, Godfrey KM, Kwek K, Chong YS, Saw SM, Pan A; GUSTO study group.

Medicine (Baltimore). 2015 Nov;94(45):e1981. doi: 10.1097/MD.0000000000001981. Erratum in: Medicine (Baltimore). 2016 Jan 22;95(3):e42ff.


Factors associated with medical student clinical reasoning and evidence based medicine practice.

Vidyarthi AR, Kamei R, Chan K, Goh SH, Lek N.

Int J Med Educ. 2015 Nov 8;6:142-8. doi: 10.5116/ijme.563a.5dd0.


Indices of central and general obesity and cardiometabolic risk among adolescents in three ethnic groups in north-west China.

Lek N, Yan W, Zhang Y, Wang Q, Cheung YB.

Ann Hum Biol. 2016;43(1):18-24. doi: 10.3109/03014460.2015.1014418. Epub 2015 Oct 2.


Sleep duration and growth outcomes across the first two years of life in the GUSTO study.

Zhou Y, Aris IM, Tan SS, Cai S, Tint MT, Krishnaswamy G, Meaney MJ, Godfrey KM, Kwek K, Gluckman PD, Chong YS, Yap F, Lek N, Gooley JJ, Lee YS.

Sleep Med. 2015 Oct;16(10):1281-6. doi: 10.1016/j.sleep.2015.07.006. Epub 2015 Jul 17.


Cockayne Syndrome due to a maternally-inherited whole gene deletion of ERCC8 and a paternally-inherited ERCC8 exon 4 deletion.

Ting TW, Brett MS, Tan ES, Shen Y, Lee SP, Lim EC, Vasanwala RF, Lek N, Thomas T, Lim KW, Tan EC.

Gene. 2015 Nov 10;572(2):274-8. doi: 10.1016/j.gene.2015.07.065. Epub 2015 Jul 22.


Unconditional and conditional standards for fetal abdominal circumference and estimated fetal weight in an ethnic Chinese population: a birth cohort study.

Xu Y, Lek N, Cheung YB, Biswas A, Su LL, Kwek KY, Yeo GS, Soh SE, Saw SM, Gluckman PD, Chong YS.

BMC Pregnancy Childbirth. 2015 Jun 25;15:141. doi: 10.1186/s12884-015-0569-1.


Experiences with a clinical reasoning and evidence-based medicine course.

Vidyarthi A, Lek N, Chan K, Kamei R.

Clin Teach. 2016 Feb;13(1):52-7. doi: 10.1111/tct.12362. Epub 2015 May 27.


Should initial investigations for neoplastic causes of precocious puberty include serum beta-human chorionic gonadotropin and alpha-fetoprotein?

Iyer P, Rajasekaran V, Lek N.

Pediatr Blood Cancer. 2015 Mar;62(3):545. doi: 10.1002/pbc.25282. Epub 2014 Oct 18. No abstract available.


Low frequency of androgen receptor gene mutations in 46 XY DSD, and fetal growth restriction.

Lek N, Miles H, Bunch T, Pilfold-Wilkie V, Tadokoro-Cuccaro R, Davies J, Ong KK, Hughes IA.

Arch Dis Child. 2014 Apr;99(4):358-61. doi: 10.1136/archdischild-2013-305338. Epub 2013 Dec 23.


Anogenital distance and penile length in infants with hypospadias or cryptorchidism: comparison with normative data.

Thankamony A, Lek N, Carroll D, Williams M, Dunger DB, Acerini CL, Ong KK, Hughes IA.

Environ Health Perspect. 2014 Feb;122(2):207-11. doi: 10.1289/ehp.1307178. Epub 2013 Dec 6.


Evaluation of three paediatric weight estimation methods in Singapore.

Loo PY, Chong SL, Lek N, Bautista D, Ng KC.

J Paediatr Child Health. 2013 Apr;49(4):E311-6. doi: 10.1111/jpc.12141. Epub 2013 Mar 14.


Picture of the month. Primary hypothyroidism.

Liew WK, Lek N, Jamuar SS, Lim KW.

Arch Pediatr Adolesc Med. 2012 Jun 1;166(6):573-4. doi: 10.1001/archpediatrics.2011.812. No abstract available.


Quantifying the risk of hypoglycaemia in children undergoing the glucagon stimulation test.

Lim SH, Vasanwala R, Lek N, Yap F.

Clin Endocrinol (Oxf). 2011 Oct;75(4):489-94. doi: 10.1111/j.1365-2265.2011.04117.x.


Risk factors for obesity in childhood survivors of suprasellar brain tumours: a retrospective study.

Lek N, Prentice P, Williams RM, Ong KK, Burke GA, Acerini CL.

Acta Paediatr. 2010 Oct;99(10):1522-6. doi: 10.1111/j.1651-2227.2010.01867.x. Epub 2010 Jun 7.


Cystic fibrosis related diabetes mellitus - diagnostic and management challenges.

Lek N, Acerini CL.

Curr Diabetes Rev. 2010 Jan;6(1):9-16. Review.


Opportunistic growth measurements are not frequently done in hospital.

Lek N, Hughes IA.

Arch Dis Child. 2009 Sep;94(9):702-4. doi: 10.1136/adc.2008.147165. Epub 2008 Nov 19.


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