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Items: 9


Tyrosine kinase 2 - Surveillant of tumours and bona fide oncogene.

Leitner NR, Witalisz-Siepracka A, Strobl B, Müller M.

Cytokine. 2017 Jan;89:209-218. doi: 10.1016/j.cyto.2015.10.015. Epub 2015 Nov 26. Review.


STAT1β is not dominant negative and is capable of contributing to gamma interferon-dependent innate immunity.

Semper C, Leitner NR, Lassnig C, Parrini M, Mahlakõiv T, Rammerstorfer M, Lorenz K, Rigler D, Müller S, Kolbe T, Vogl C, Rülicke T, Staeheli P, Decker T, Müller M, Strobl B.

Mol Cell Biol. 2014 Jun;34(12):2235-48. doi: 10.1128/MCB.00295-14. Epub 2014 Apr 7.


Conditional ablation of TYK2 in immunity to viral infection and tumor surveillance.

Vielnascher RM, Hainzl E, Leitner NR, Rammerstorfer M, Popp D, Witalisz A, Rom R, Karaghiosoff M, Kolbe T, Müller S, Rülicke T, Lassnig C, Strobl B, Müller M.

Transgenic Res. 2014 Jun;23(3):519-29. doi: 10.1007/s11248-014-9795-y. Epub 2014 Apr 3.


Lactotransferrin-Cre reporter mice trace neutrophils, monocytes/macrophages and distinct subtypes of dendritic cells.

Kovacic B, Hoelbl-Kovacic A, Fischhuber KM, Leitner NR, Gotthardt D, Casanova E, Sexl V, Müller M.

Haematologica. 2014 Jun;99(6):1006-15. doi: 10.3324/haematol.2013.097154. Epub 2014 Feb 21.


Inducible, dose-adjustable and time-restricted reconstitution of STAT1 deficiency in vivo.

Leitner NR, Lassnig C, Rom R, Heider S, Bago-Horvath Z, Eferl R, Müller S, Kolbe T, Kenner L, Rülicke T, Strobl B, Müller M.

PLoS One. 2014 Jan 29;9(1):e86608. doi: 10.1371/journal.pone.0086608. eCollection 2014.


TYK2 kinase activity is required for functional type I interferon responses in vivo.

Prchal-Murphy M, Semper C, Lassnig C, Wallner B, Gausterer C, Teppner-Klymiuk I, Kobolak J, Müller S, Kolbe T, Karaghiosoff M, Dinnyés A, Rülicke T, Leitner NR, Strobl B, Müller M.

PLoS One. 2012;7(6):e39141. doi: 10.1371/journal.pone.0039141. Epub 2012 Jun 18.


A comparative proteome analysis links tyrosine kinase 2 (Tyk2) to the regulation of cellular glucose and lipid metabolism in response to poly(I:C).

Grunert T, Leitner NR, Marchetti-Deschmann M, Miller I, Wallner B, Radwan M, Vogl C, Kolbe T, Kratky D, Gemeiner M, Allmaier G, Müller M, Strobl B.

J Proteomics. 2011 Nov 18;74(12):2866-80. doi: 10.1016/j.jprot.2011.07.006. Epub 2011 Jul 23.


Generation of mice with a conditional Stat1 null allele.

Wallner B, Leitner NR, Vielnascher RM, Kernbauer E, Kolbe T, Karaghiosoff M, Rülicke T, Decker T, Müller M.

Transgenic Res. 2012 Feb;21(1):217-24. doi: 10.1007/s11248-011-9519-5. Epub 2011 May 7.


A time- and dose-dependent STAT1 expression system.

Leitner NR, Strobl B, Bokor M, Painz R, Kolbe T, Rülicke T, Müller M, Karaghiosoff M.

BMC Biotechnol. 2006 Dec 21;6:48.

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