Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 48

1.

Imprinting Directionality into Proton Transfer Reactions of an Achiral Molecule.

Kügel J, Leisegang M, Bode M.

ACS Nano. 2018 Aug 28;12(8):8733-8738. doi: 10.1021/acsnano.8b04868. Epub 2018 Aug 9.

PMID:
30086226
2.

The histone demethylase Jarid1b mediates angiotensin II-induced endothelial dysfunction by controlling the 3'UTR of soluble epoxide hydrolase.

Vasconez AE, Janetzko P, Oo JA, Pflüger-Müller B, Ratiu C, Gu L, Helin K, Geisslinger G, Fleming I, Schröder K, Fork C, Brandes RP, Leisegang MS.

Acta Physiol (Oxf). 2018 Aug 4:e13168. doi: 10.1111/apha.13168. [Epub ahead of print]

PMID:
30076673
3.

Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells.

Hitzel J, Lee E, Zhang Y, Bibli SI, Li X, Zukunft S, Pflüger B, Hu J, Schürmann C, Vasconez AE, Oo JA, Kratzer A, Kumar S, Rezende F, Josipovic I, Thomas D, Giral H, Schreiber Y, Geisslinger G, Fork C, Yang X, Sigala F, Romanoski CE, Kroll J, Jo H, Landmesser U, Lusis AJ, Namgaladze D, Fleming I, Leisegang MS, Zhu J, Brandes RP.

Nat Commun. 2018 Jun 12;9(1):2292. doi: 10.1038/s41467-018-04602-0.

4.

Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor-Engineered T Cells for Ovarian Cancer.

Matsuda T, Leisegang M, Park JH, Ren L, Kato T, Ikeda Y, Harada M, Kiyotani K, Lengyel E, Fleming GF, Nakamura Y.

Clin Cancer Res. 2018 May 2. doi: 10.1158/1078-0432.CCR-18-0142. [Epub ahead of print]

PMID:
29720506
5.

Targeting Merkel Cell Carcinoma by Engineered T Cells Specific to T-Antigens of Merkel Cell Polyomavirus.

Gavvovidis I, Leisegang M, Willimsky G, Miller N, Nghiem P, Blankenstein T.

Clin Cancer Res. 2018 Aug 1;24(15):3644-3655. doi: 10.1158/1078-0432.CCR-17-2661. Epub 2018 Apr 18.

PMID:
29669806
6.

Effective screening of T cells recognizing neoantigens and construction of T-cell receptor-engineered T cells.

Kato T, Matsuda T, Ikeda Y, Park JH, Leisegang M, Yoshimura S, Hikichi T, Harada M, Zewde M, Sato S, Hasegawa K, Kiyotani K, Nakamura Y.

Oncotarget. 2018 Jan 13;9(13):11009-11019. doi: 10.18632/oncotarget.24232. eCollection 2018 Feb 16.

7.

Analyzing the Wave Nature of Hot Electrons with a Molecular Nanoprobe.

Leisegang M, Kügel J, Klein L, Bode M.

Nano Lett. 2018 Mar 14;18(3):2165-2171. doi: 10.1021/acs.nanolett.8b00465. Epub 2018 Mar 1.

PMID:
29486560
8.

LET's sponge: How the lncRNA PFL promotes cardiac fibrosis.

Leisegang MS.

Theranostics. 2018 Jan 1;8(4):874-877. doi: 10.7150/thno.23364. eCollection 2018.

9.

Long noncoding RNA LISPR1 is required for S1P signaling and endothelial cell function.

Josipovic I, Pflüger B, Fork C, Vasconez AE, Oo JA, Hitzel J, Seredinski S, Gamen E, Heringdorf DMZ, Chen W, Looso M, Pullamsetti SS, Brandes RP, Leisegang MS.

J Mol Cell Cardiol. 2018 Mar;116:57-68. doi: 10.1016/j.yjmcc.2018.01.015. Epub 2018 Feb 3.

PMID:
29408197
10.

A positive feedback loop between IL-1β, LPS and NEU1 may promote atherosclerosis by enhancing a pro-inflammatory state in monocytes and macrophages.

Sieve I, Ricke-Hoch M, Kasten M, Battmer K, Stapel B, Falk CS, Leisegang MS, Haverich A, Scherr M, Hilfiker-Kleiner D.

Vascul Pharmacol. 2018 Apr;103-105:16-28. doi: 10.1016/j.vph.2018.01.005. Epub 2018 Jan 31.

PMID:
29371126
11.

Conserved Gene Microsynteny Unveils Functional Interaction Between Protein Disulfide Isomerase and Rho Guanine-Dissociation Inhibitor Families.

Moretti AIS, Pavanelli JC, Nolasco P, Leisegang MS, Tanaka LY, Fernandes CG, Wosniak J Jr, Kajihara D, Dias MH, Fernandes DC, Jo H, Tran NV, Ebersberger I, Brandes RP, Bonatto D, Laurindo FRM.

Sci Rep. 2017 Dec 8;7(1):17262. doi: 10.1038/s41598-017-16947-5.

12.

Redox Regulation and Noncoding RNAs.

Leisegang MS, Schröder K, Brandes RP.

Antioxid Redox Signal. 2018 Sep 20;29(9):793-812. doi: 10.1089/ars.2017.7276. Epub 2017 Sep 18.

PMID:
28816061
13.

Remote Single-Molecule Switching: Identification and Nanoengineering of Hot Electron-Induced Tautomerization.

Kügel J, Leisegang M, Böhme M, Krönlein A, Sixta A, Bode M.

Nano Lett. 2017 Aug 9;17(8):5106-5112. doi: 10.1021/acs.nanolett.7b02419. Epub 2017 Jul 26.

PMID:
28732159
14.

Chimeric PD-1:28 Receptor Upgrades Low-Avidity T cells and Restores Effector Function of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy.

Schlenker R, Olguín-Contreras LF, Leisegang M, Schnappinger J, Disovic A, Rühland S, Nelson PJ, Leonhardt H, Harz H, Wilde S, Schendel DJ, Uckert W, Willimsky G, Noessner E.

Cancer Res. 2017 Jul 1;77(13):3577-3590. doi: 10.1158/0008-5472.CAN-16-1922. Epub 2017 May 22.

15.

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression.

Kammertoens T, Friese C, Arina A, Idel C, Briesemeister D, Rothe M, Ivanov A, Szymborska A, Patone G, Kunz S, Sommermeyer D, Engels B, Leisegang M, Textor A, Fehling HJ, Fruttiger M, Lohoff M, Herrmann A, Yu H, Weichselbaum R, Uckert W, Hübner N, Gerhardt H, Beule D, Schreiber H, Blankenstein T.

Nature. 2017 May 4;545(7652):98-102. doi: 10.1038/nature22311. Epub 2017 Apr 26.

16.

Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function.

Leisegang MS, Fork C, Josipovic I, Richter FM, Preussner J, Hu J, Miller MJ, Epah J, Hofmann P, Günther S, Moll F, Valasarajan C, Heidler J, Ponomareva Y, Freiman TM, Maegdefessel L, Plate KH, Mittelbronn M, Uchida S, Künne C, Stellos K, Schermuly RT, Weissmann N, Devraj K, Wittig I, Boon RA, Dimmeler S, Pullamsetti SS, Looso M, Miller FJ Jr, Brandes RP.

Circulation. 2017 Jul 4;136(1):65-79. doi: 10.1161/CIRCULATIONAHA.116.026991. Epub 2017 Mar 28.

17.

Epigenetic control of microsomal prostaglandin E synthase-1 by HDAC-mediated recruitment of p300.

Fork C, Vasconez AE, Janetzko P, Angioni C, Schreiber Y, Ferreirós N, Geisslinger G, Leisegang MS, Steinhilber D, Brandes RP.

J Lipid Res. 2017 Feb;58(2):386-392. doi: 10.1194/jlr.M072280. Epub 2016 Dec 2.

18.

CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity.

Prior KK, Leisegang MS, Josipovic I, Löwe O, Shah AM, Weissmann N, Schröder K, Brandes RP.

Redox Biol. 2016 Oct;9:287-295. doi: 10.1016/j.redox.2016.08.013. Epub 2016 Aug 24.

19.

The NADPH Oxidase Nox2 Mediates Vitamin D-Induced Vascular Regeneration in Male Mice.

Leisegang MS, Babelova A, Wong MS, Helfinger V, Weißmann N, Brandes RP, Schröder K.

Endocrinology. 2016 Oct;157(10):4032-4040. Epub 2016 Jul 11.

PMID:
27399878
20.

PAFAH1B1 and the lncRNA NONHSAT073641 maintain an angiogenic phenotype in human endothelial cells.

Josipovic I, Fork C, Preussner J, Prior KK, Iloska D, Vasconez AE, Labocha S, Angioni C, Thomas D, Ferreirós N, Looso M, Pullamsetti SS, Geisslinger G, Steinhilber D, Brandes RP, Leisegang MS.

Acta Physiol (Oxf). 2016 Sep;218(1):13-27. doi: 10.1111/apha.12700. Epub 2016 May 20.

PMID:
27124368
21.

The Endoplasmic Reticulum Chaperone Calnexin Is a NADPH Oxidase NOX4 Interacting Protein.

Prior KK, Wittig I, Leisegang MS, Groenendyk J, Weissmann N, Michalak M, Jansen-Dürr P, Shah AM, Brandes RP.

J Biol Chem. 2016 Mar 25;291(13):7045-59. doi: 10.1074/jbc.M115.710772. Epub 2016 Feb 9.

22.

Targeting human melanoma neoantigens by T cell receptor gene therapy.

Leisegang M, Kammertoens T, Uckert W, Blankenstein T.

J Clin Invest. 2016 Mar 1;126(3):854-8. doi: 10.1172/JCI83465. Epub 2016 Jan 25.

23.

The Histone Demethylase PHF8 Is Essential for Endothelial Cell Migration.

Gu L, Hitzel J, Moll F, Kruse C, Malik RA, Preussner J, Looso M, Leisegang MS, Steinhilber D, Brandes RP, Fork C.

PLoS One. 2016 Jan 11;11(1):e0146645. doi: 10.1371/journal.pone.0146645. eCollection 2016.

24.

Eukaryotic Hsp70 chaperones in the intermembrane space of chloroplasts.

Bionda T, Gross LE, Becker T, Papasotiriou DG, Leisegang MS, Karas M, Schleiff E.

Planta. 2016 Mar;243(3):733-47. doi: 10.1007/s00425-015-2440-z. Epub 2015 Dec 15.

PMID:
26669598
25.

Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.

Leisegang M, Engels B, Schreiber K, Yew PY, Kiyotani K, Idel C, Arina A, Duraiswamy J, Weichselbaum RR, Uckert W, Nakamura Y, Schreiber H.

Clin Cancer Res. 2016 Jun 1;22(11):2734-43. doi: 10.1158/1078-0432.CCR-15-2361. Epub 2015 Dec 14.

26.

Response to letter regarding article, "Vitamin D promotes vascular regeneration".

Ka Wong MS, Leisegang MS, Kruse C, Vogel J, Schürmann C, Dehne N, Weigert A, Herrmann E, Brüne B, Shah AM, Steinhilber D, Offermanns S, Carmeliet G, Badenhoop K, Schröder K, Brandes RP.

Circulation. 2015 Jun 2;131(22):e515-6. doi: 10.1161/CIRCULATIONAHA.114.014781. No abstract available.

27.

Epigenetic Regulation of Angiogenesis by JARID1B-Induced Repression of HOXA5.

Fork C, Gu L, Hitzel J, Josipovic I, Hu J, SzeKa Wong M, Ponomareva Y, Albert M, Schmitz SU, Uchida S, Fleming I, Helin K, Steinhilber D, Leisegang MS, Brandes RP.

Arterioscler Thromb Vasc Biol. 2015 Jul;35(7):1645-52. doi: 10.1161/ATVBAHA.115.305561. Epub 2015 May 28.

PMID:
26023081
28.

Identification of human T-cell receptors with optimal affinity to cancer antigens using antigen-negative humanized mice.

Obenaus M, Leitão C, Leisegang M, Chen X, Gavvovidis I, van der Bruggen P, Uckert W, Schendel DJ, Blankenstein T.

Nat Biotechnol. 2015 Apr;33(4):402-7. doi: 10.1038/nbt.3147. Epub 2015 Mar 16.

PMID:
25774714
29.

Targeting cancer-specific mutations by T cell receptor gene therapy.

Blankenstein T, Leisegang M, Uckert W, Schreiber H.

Curr Opin Immunol. 2015 Apr;33:112-9. doi: 10.1016/j.coi.2015.02.005. Epub 2015 Feb 27. Review.

30.

The association of late-acting snoRNPs with human pre-ribosomal complexes requires the RNA helicase DDX21.

Sloan KE, Leisegang MS, Doebele C, Ramírez AS, Simm S, Safferthal C, Kretschmer J, Schorge T, Markoutsa S, Haag S, Karas M, Ebersberger I, Schleiff E, Watkins NJ, Bohnsack MT.

Nucleic Acids Res. 2015 Jan;43(1):553-64. doi: 10.1093/nar/gku1291. Epub 2014 Dec 4.

31.

HEK293-based production platform for γ-retroviral (self-inactivating) vectors: application for safe and efficient transfer of COL7A1 cDNA.

Hennig K, Raasch L, Kolbe C, Weidner S, Leisegang M, Uckert W, Titeux M, Hovnanian A, Kuehlcke K, Loew R.

Hum Gene Ther Clin Dev. 2014 Dec;25(4):218-28. doi: 10.1089/humc.2014.083.

PMID:
25381930
32.

Vitamin D promotes vascular regeneration.

Wong MS, Leisegang MS, Kruse C, Vogel J, Schürmann C, Dehne N, Weigert A, Herrmann E, Brüne B, Shah AM, Steinhilber D, Offermanns S, Carmeliet G, Badenhoop K, Schröder K, Brandes RP.

Circulation. 2014 Sep 16;130(12):976-86. doi: 10.1161/CIRCULATIONAHA.114.010650. Epub 2014 Jul 11.

PMID:
25015343
33.

The evolution of the ribosome biogenesis pathway from a yeast perspective.

Ebersberger I, Simm S, Leisegang MS, Schmitzberger P, Mirus O, von Haeseler A, Bohnsack MT, Schleiff E.

Nucleic Acids Res. 2014 Feb;42(3):1509-23. doi: 10.1093/nar/gkt1137. Epub 2013 Nov 14.

34.

Monoamine oxidases are mediators of endothelial dysfunction in the mouse aorta.

Sturza A, Leisegang MS, Babelova A, Schröder K, Benkhoff S, Loot AE, Fleming I, Schulz R, Muntean DM, Brandes RP.

Hypertension. 2013 Jul;62(1):140-6. doi: 10.1161/HYPERTENSIONAHA.113.01314. Epub 2013 May 13.

PMID:
23670301
35.

Defining the core proteome of the chloroplast envelope membranes.

Simm S, Papasotiriou DG, Ibrahim M, Leisegang MS, Müller B, Schorge T, Karas M, Mirus O, Sommer MS, Schleiff E.

Front Plant Sci. 2013 Feb 6;4:11. doi: 10.3389/fpls.2013.00011. eCollection 2013.

36.

Exportin t and Exportin 5: tRNA and miRNA biogenesis - and beyond.

Leisegang MS, Martin R, Ramírez AS, Bohnsack MT.

Biol Chem. 2012 Jul;393(7):599-604. doi: 10.1515/hsz-2012-0146. Review.

PMID:
22944664
37.

Protective capacity of virus-specific T cell receptor-transduced CD8 T cells in vivo.

Mueller K, von Mässenhausen A, Aichele U, Stärck L, Leisegang M, Uckert W, Pircher H.

J Virol. 2012 Oct;86(19):10866-9. doi: 10.1128/JVI.01472-12. Epub 2012 Jul 11.

38.

Human antitumor CD8+ T cells producing Th1 polycytokines show superior antigen sensitivity and tumor recognition.

Wilde S, Sommermeyer D, Leisegang M, Frankenberger B, Mosetter B, Uckert W, Schendel DJ.

J Immunol. 2012 Jul 15;189(2):598-605. doi: 10.4049/jimmunol.1102165. Epub 2012 Jun 11.

39.

TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.

Spranger S, Jeremias I, Wilde S, Leisegang M, Stärck L, Mosetter B, Uckert W, Heemskerk MH, Schendel DJ, Frankenberger B.

Blood. 2012 Apr 12;119(15):3440-9. doi: 10.1182/blood-2011-06-357939. Epub 2012 Feb 27.

40.

The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed.

Popovic J, Li LP, Kloetzel PM, Leisegang M, Uckert W, Blankenstein T.

Blood. 2011 Jul 28;118(4):946-54. doi: 10.1182/blood-2010-12-325035. Epub 2011 May 25.

41.

A high-definition native polyacrylamide gel electrophoresis system for the analysis of membrane complexes.

Ladig R, Sommer MS, Hahn A, Leisegang MS, Papasotiriou DG, Ibrahim M, Elkehal R, Karas M, Zickermann V, Gutensohn M, Brandt U, Klösgen RB, Schleiff E.

Plant J. 2011 Jul;67(1):181-94. doi: 10.1111/j.1365-313X.2011.04577.x. Epub 2011 Apr 28.

42.

MHC-restricted fratricide of human lymphocytes expressing survivin-specific transgenic T cell receptors.

Leisegang M, Wilde S, Spranger S, Milosevic S, Frankenberger B, Uckert W, Schendel DJ.

J Clin Invest. 2010 Nov;120(11):3869-77. doi: 10.1172/JCI43437. Epub 2010 Oct 11.

43.

The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Ψ1191 in yeast 18S rRNA.

Meyer B, Wurm JP, Kötter P, Leisegang MS, Schilling V, Buchhaupt M, Held M, Bahr U, Karas M, Heckel A, Bohnsack MT, Wöhnert J, Entian KD.

Nucleic Acids Res. 2011 Mar;39(4):1526-37. doi: 10.1093/nar/gkq931. Epub 2010 Oct 23.

44.

Targeting the epidermal growth factor receptor (HER) family by T cell receptor gene-modified T lymphocytes.

Meyerhuber P, Conrad H, Stärck L, Leisegang M, Busch DH, Uckert W, Bernhard H.

J Mol Med (Berl). 2010 Nov;88(11):1113-21. doi: 10.1007/s00109-010-0660-z. Epub 2010 Aug 11.

PMID:
20700725
45.

T-cell receptor gene-modified T cells with shared renal cell carcinoma specificity for adoptive T-cell therapy.

Leisegang M, Turqueti-Neves A, Engels B, Blankenstein T, Schendel DJ, Uckert W, Noessner E.

Clin Cancer Res. 2010 Apr 15;16(8):2333-43. doi: 10.1158/1078-0432.CCR-09-2897. Epub 2010 Apr 6.

46.

A single TCR alpha-chain with dominant peptide recognition in the allorestricted HER2/neu-specific T cell repertoire.

Liang X, Weigand LU, Schuster IG, Eppinger E, van der Griendt JC, Schub A, Leisegang M, Sommermeyer D, Anderl F, Han Y, Ellwart J, Moosmann A, Busch DH, Uckert W, Peschel C, Krackhardt AM.

J Immunol. 2010 Feb 1;184(3):1617-29. doi: 10.4049/jimmunol.0902155. Epub 2009 Dec 30.

47.

Enhanced functionality of T cell receptor-redirected T cells is defined by the transgene cassette.

Leisegang M, Engels B, Meyerhuber P, Kieback E, Sommermeyer D, Xue SA, Reuss S, Stauss H, Uckert W.

J Mol Med (Berl). 2008 May;86(5):573-83. doi: 10.1007/s00109-008-0317-3. Epub 2008 Mar 12. Erratum in: J Mol Med. 2008 Jul;86(7):855.

PMID:
18335188
48.

Designer T cells by T cell receptor replacement.

Sommermeyer D, Neudorfer J, Weinhold M, Leisegang M, Engels B, Noessner E, Heemskerk MH, Charo J, Schendel DJ, Blankenstein T, Bernhard H, Uckert W.

Eur J Immunol. 2006 Nov;36(11):3052-9.

Supplemental Content

Loading ...
Support Center