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Items: 1 to 50 of 103

1.

How Does Aldosterone Work in the β-Intercalated Cell?

Leipziger J, Praetorius H.

J Am Soc Nephrol. 2020 Feb 13. pii: ASN.2020010077. doi: 10.1681/ASN.2020010077. [Epub ahead of print] No abstract available.

PMID:
32065116
2.

Renal autocrine and paracrine signaling -a story of self-protection.

Leipziger J, Praetorius HA.

Physiol Rev. 2020 Jan 30. doi: 10.1152/physrev.00014.2019. [Epub ahead of print]

PMID:
31999508
3.

Extracellular Nucleotides and P2 Receptors in Renal Function.

Vallon V, Unwin R, Inscho EW, Leipziger J, Kishore BK.

Physiol Rev. 2020 Jan 1;100(1):211-269. doi: 10.1152/physrev.00038.2018. Epub 2019 Aug 22.

PMID:
31437091
4.

[Introduction on how to write a scientific abstract].

Kaspersen AE, Hasenkam JM, Leipziger JG, Djurhuus JC.

Ugeskr Laeger. 2019 May 20;181(21). pii: V02190103. Danish.

PMID:
31124438
5.

Vasopressin Increases Urinary Acidification via V1a Receptors in Collecting Duct Intercalated Cells.

Giesecke T, Himmerkus N, Leipziger J, Bleich M, Koshimizu TA, Fähling M, Smorodchenko A, Shpak J, Knappe C, Isermann J, Ayasse N, Kawahara K, Schmoranzer J, Gimber N, Paliege A, Bachmann S, Mutig K.

J Am Soc Nephrol. 2019 Jun;30(6):946-961. doi: 10.1681/ASN.2018080816. Epub 2019 May 16.

PMID:
31097611
6.

The renal and blood pressure response to low sodium diet in P2X4 receptor knockout mice.

Craigie E, Menzies RI, Larsen CK, Jacquillet G, Carrel M, Wildman SS, Loffing J, Leipziger J, Shirley DG, Bailey MA, Unwin RJ.

Physiol Rep. 2018 Oct;6(20):e13899. doi: 10.14814/phy2.13899.

7.

Cystic fibrosis: Beyond the airways. Report on the meeting of the basic science working group in Loutraki, Greece.

Amaral MD, Boj SF, Shaw J, Leipziger J, Beekman JM.

J Cyst Fibros. 2018 Jul;17(4):441-443. doi: 10.1016/j.jcf.2018.05.008. Epub 2018 Jun 2. Review.

PMID:
29866530
8.

Hydrochlorothiazide and acute urinary acidification: The "voltage hypothesis" of ENaC-dependent H+ secretion refuted.

Ayasse N, de Bruijn PIA, Berg P, Sørensen MV, Leipziger J.

Acta Physiol (Oxf). 2018 May;223(1):e13013. doi: 10.1111/apha.13013. Epub 2017 Dec 29.

PMID:
29226589
9.

Exocrine secretion spelled with a capital K+ (BK).

Leipziger J.

J Physiol. 2017 Jul 15;595(14):4585. doi: 10.1113/JP274588. Epub 2017 Jun 16. No abstract available.

10.

Loop Diuretics Diminish Hemolysis Induced by α-Hemolysin from Escherichia coli.

Söderström CM, Fagerberg SK, Brogaard MB, Leipziger J, Skals M, Praetorius HA.

J Membr Biol. 2017 Jun;250(3):301-313. doi: 10.1007/s00232-017-9963-0. Epub 2017 May 9.

PMID:
28488084
11.

Intact colonic KCa1.1 channel activity in KCNMB2 knockout mice.

Larsen CK, Praetorius HA, Leipziger J, Sorensen MV.

Physiol Rep. 2017 Mar;5(5). pii: e13179. doi: 10.14814/phy2.13179.

12.

P2X Receptors Inhibit NaCl Absorption in mTAL Independently of Nitric Oxide.

Svendsen SL, Isidor S, Praetorius HA, Leipziger J.

Front Physiol. 2017 Jan 24;8:18. doi: 10.3389/fphys.2017.00018. eCollection 2017.

13.

AVP dynamically increases paracellular Na+ permeability and transcellular NaCl transport in the medullary thick ascending limb of Henle's loop.

Himmerkus N, Plain A, Marques RD, Sonntag SR, Paliege A, Leipziger J, Bleich M.

Pflugers Arch. 2017 Jan;469(1):149-158. doi: 10.1007/s00424-016-1915-5. Epub 2016 Dec 6. Review.

PMID:
27924355
14.

P2Y2R is a direct target of HIF-1α and mediates secretion-dependent cyst growth of renal cyst-forming epithelial cells.

Kraus A, Grampp S, Goppelt-Struebe M, Schreiber R, Kunzelmann K, Peters DJ, Leipziger J, Schley G, Schödel J, Eckardt KU, Buchholz B.

Purinergic Signal. 2016 Dec;12(4):687-695. Epub 2016 Aug 26.

15.

Na(+) dependence of K(+) -induced natriuresis, kaliuresis and Na(+) /Cl(-) cotransporter dephosphorylation.

Jensen IS, Larsen CK, Leipziger J, Sørensen MV.

Acta Physiol (Oxf). 2016 Sep;218(1):49-61. doi: 10.1111/apha.12707. Epub 2016 Jun 15.

PMID:
27172453
16.

Hyperaldosteronism after decreased renal K+ excretion in KCNMB2 knockout mice.

Larsen CK, Jensen IS, Sorensen MV, de Bruijn PI, Bleich M, Praetorius HA, Leipziger J.

Am J Physiol Renal Physiol. 2016 May 15;310(10):F1035-46. doi: 10.1152/ajprenal.00010.2016. Epub 2016 Mar 9.

17.

Furosemide-induced urinary acidification is caused by pronounced H+ secretion in the thick ascending limb.

de Bruijn PI, Larsen CK, Frische S, Himmerkus N, Praetorius HA, Bleich M, Leipziger J.

Am J Physiol Renal Physiol. 2015 Jul 15;309(2):F146-53.

18.

[Ca2+]i Oscillations and IL-6 Release Induced by α-Hemolysin from Escherichia coli Require P2 Receptor Activation in Renal Epithelia.

Christensen MG, Fagerberg SK, de Bruijn PI, Bjaelde RG, Jakobsen H, Leipziger J, Skals M, Praetorius HA.

J Biol Chem. 2015 Jun 5;290(23):14776-84. doi: 10.1074/jbc.M115.639526. Epub 2015 Apr 24.

19.

P2X receptors trigger intracellular alkalization in isolated perfused mouse medullary thick ascending limb.

de Bruijn PI, Bleich M, Praetorius HA, Leipziger J.

Acta Physiol (Oxf). 2015 Jan;213(1):277-84. doi: 10.1111/apha.12417. Epub 2014 Nov 24.

20.

Bacterial RTX toxins allow acute ATP release from human erythrocytes directly through the toxin pore.

Skals M, Bjaelde RG, Reinholdt J, Poulsen K, Vad BS, Otzen DE, Leipziger J, Praetorius HA.

J Biol Chem. 2014 Jul 4;289(27):19098-109. doi: 10.1074/jbc.M114.571414. Epub 2014 May 23.

21.

Sialic acid residues are essential for cell lysis mediated by leukotoxin from Aggregatibacter actinomycetemcomitans.

Munksgaard PS, Skals M, Reinholdt J, Poulsen K, Jensen MR, Yang C, Leipziger J, Vorup-Jensen T, Praetorius HA.

Infect Immun. 2014 Jun;82(6):2219-28. doi: 10.1128/IAI.01647-14. Epub 2014 Mar 18.

22.

P2X4 receptor regulation of transient receptor potential melastatin type 6 (TRPM6) Mg2+ channels.

de Baaij JH, Blanchard MG, Lavrijsen M, Leipziger J, Bindels RJ, Hoenderop JG.

Pflugers Arch. 2014 Oct;466(10):1941-52. doi: 10.1007/s00424-014-1440-3. Epub 2014 Jan 12.

PMID:
24413910
23.

P2Y2 receptor knock-out mice display normal NaCl absorption in medullary thick ascending limb.

Marques RD, Praetorius HA, Leipziger J.

Front Physiol. 2013 Oct 9;4:280. doi: 10.3389/fphys.2013.00280. eCollection 2013.

24.

Renal epithelial cells can release ATP by vesicular fusion.

Bjaelde RG, Arnadottir SS, Overgaard MT, Leipziger J, Praetorius HA.

Front Physiol. 2013 Sep 19;4:238. doi: 10.3389/fphys.2013.00238. eCollection 2013.

25.

P2X receptor-dependent erythrocyte damage by α-hemolysin from Escherichia coli triggers phagocytosis by THP-1 cells.

Fagerberg SK, Skals M, Leipziger J, Praetorius HA.

Toxins (Basel). 2013 Mar 5;5(3):472-87. doi: 10.3390/toxins5030472.

26.

P2X receptor stimulation amplifies complement-induced haemolysis.

Hejl JL, Skals M, Leipziger J, Praetorius HA.

Pflugers Arch. 2013 Apr;465(4):529-41. doi: 10.1007/s00424-012-1174-z. Epub 2012 Nov 14.

PMID:
23149487
27.

Primary cilium-dependent sensing of urinary flow and paracrine purinergic signaling.

Praetorius HA, Leipziger J.

Semin Cell Dev Biol. 2013 Jan;24(1):3-10. doi: 10.1016/j.semcdb.2012.10.003. Epub 2012 Oct 17. Review.

PMID:
23085624
28.

Leukotoxin from Aggregatibacter actinomycetemcomitans causes shrinkage and P2X receptor-dependent lysis of human erythrocytes.

Munksgaard PS, Vorup-Jensen T, Reinholdt J, Söderström CM, Poulsen K, Leipziger J, Praetorius HA, Skals M.

Cell Microbiol. 2012 Dec;14(12):1904-20. doi: 10.1111/cmi.12021. Epub 2012 Sep 25.

PMID:
22906303
29.

Transient P2X7 receptor activation triggers macrophage death independent of Toll-like receptors 2 and 4, caspase-1, and pannexin-1 proteins.

Hanley PJ, Kronlage M, Kirschning C, del Rey A, Di Virgilio F, Leipziger J, Chessell IP, Sargin S, Filippov MA, Lindemann O, Mohr S, Königs V, Schillers H, Bähler M, Schwab A.

J Biol Chem. 2012 Mar 23;287(13):10650-63. doi: 10.1074/jbc.M111.332676. Epub 2012 Jan 10.

30.

Basolateral P2X receptors mediate inhibition of NaCl transport in mouse medullary thick ascending limb (mTAL).

Marques RD, de Bruijn PI, Sorensen MV, Bleich M, Praetorius HA, Leipziger J.

Am J Physiol Renal Physiol. 2012 Feb 15;302(4):F487-94. doi: 10.1152/ajprenal.00570.2011. Epub 2011 Nov 23.

31.

Python erythrocytes are resistant to α-hemolysin from Escherichia coli.

Larsen CK, Skals M, Wang T, Cheema MU, Leipziger J, Praetorius HA.

J Membr Biol. 2011 Dec;244(3):131-40. doi: 10.1007/s00232-011-9406-2. Epub 2011 Nov 8.

PMID:
22064954
32.

Agonists that increase [Ca²⁺](i) halt the movement of acidic cytoplasmic vesicles in MDCK cells.

Bjaelde RG, Arnadottir SS, Leipziger J, Praetorius HA.

J Membr Biol. 2011 Nov;244(1):43-53. doi: 10.1007/s00232-011-9396-0. Epub 2011 Oct 12.

PMID:
21989951
33.

Haemolysis induced by α-toxin from Staphylococcus aureus requires P2X receptor activation.

Skals M, Leipziger J, Praetorius HA.

Pflugers Arch. 2011 Nov;462(5):669-79. doi: 10.1007/s00424-011-1010-x. Epub 2011 Aug 17.

PMID:
21847558
34.

UTP reduces infarct size and improves mice heart function after myocardial infarct via P2Y2 receptor.

Cohen R, Shainberg A, Hochhauser E, Cheporko Y, Tobar A, Birk E, Pinhas L, Leipziger J, Don J, Porat E.

Biochem Pharmacol. 2011 Nov 1;82(9):1126-33. doi: 10.1016/j.bcp.2011.07.094. Epub 2011 Aug 3.

PMID:
21839729
35.

The secretory KCa1.1 channel localises to crypts of distal mouse colon: functional and molecular evidence.

Sørensen MV, Strandsby AB, Larsen CK, Praetorius HA, Leipziger J.

Pflugers Arch. 2011 Nov;462(5):745-52. doi: 10.1007/s00424-011-1000-z. Epub 2011 Aug 6.

PMID:
21822598
36.

Luminal nucleotides are tonic inhibitors of renal tubular transport.

Leipziger J.

Curr Opin Nephrol Hypertens. 2011 Sep;20(5):518-22. doi: 10.1097/MNH.0b013e3283487393. Review.

PMID:
21670675
37.

Extracellular nucleotide derivatives protect cardiomyocytes against hypoxic stress.

Golan O, Issan Y, Isak A, Leipziger J, Robaye B, Shainberg A.

Biochem Pharmacol. 2011 May 15;81(10):1219-27. doi: 10.1016/j.bcp.2011.02.007. Epub 2011 Mar 3.

PMID:
21376706
38.

Impaired aldosterone responsiveness in corticosteroid binding globulin deficient mice.

Sorensen MV, Praetorius HA, Nykjaer A, Willnow T, Leipziger J.

Acta Physiol (Oxf). 2011 Jan;201(1):169-77. doi: 10.1111/j.1748-1716.2010.02208.x. Epub 2010 Nov 12.

PMID:
20969731
39.

Autocrine purinergic receptor signaling is essential for macrophage chemotaxis.

Kronlage M, Song J, Sorokin L, Isfort K, Schwerdtle T, Leipziger J, Robaye B, Conley PB, Kim HC, Sargin S, Schön P, Schwab A, Hanley PJ.

Sci Signal. 2010 Jul 27;3(132):ra55. doi: 10.1126/scisignal.2000588.

40.

Adrenaline-induced colonic K+ secretion is mediated by KCa1.1 (BK) channels.

Sørensen MV, Sausbier M, Ruth P, Seidler U, Riederer B, Praetorius HA, Leipziger J.

J Physiol. 2010 May 15;588(Pt 10):1763-77. doi: 10.1113/jphysiol.2009.181933. Epub 2010 Mar 29.

41.

Escherichia coli alpha-hemolysin triggers shrinkage of erythrocytes via K(Ca)3.1 and TMEM16A channels with subsequent phosphatidylserine exposure.

Skals M, Jensen UB, Ousingsawat J, Kunzelmann K, Leipziger J, Praetorius HA.

J Biol Chem. 2010 May 14;285(20):15557-65. doi: 10.1074/jbc.M109.082578. Epub 2010 Mar 15.

42.

Intrarenal purinergic signaling in the control of renal tubular transport.

Praetorius HA, Leipziger J.

Annu Rev Physiol. 2010;72:377-93. doi: 10.1146/annurev-physiol-021909-135825. Review.

PMID:
20148681
43.

Colonic potassium handling.

Sorensen MV, Matos JE, Praetorius HA, Leipziger J.

Pflugers Arch. 2010 Apr;459(5):645-56. doi: 10.1007/s00424-009-0781-9. Epub 2010 Feb 10. Review.

PMID:
20143237
44.

AVP-stimulated nucleotide secretion in perfused mouse medullary thick ascending limb and cortical collecting duct.

Odgaard E, Praetorius HA, Leipziger J.

Am J Physiol Renal Physiol. 2009 Aug;297(2):F341-9. doi: 10.1152/ajprenal.00190.2009. Epub 2009 Jun 10.

45.

Released nucleotides amplify the cilium-dependent, flow-induced [Ca2+]i response in MDCK cells.

Praetorius HA, Leipziger J.

Acta Physiol (Oxf). 2009 Nov;197(3):241-51. doi: 10.1111/j.1748-1716.2009.02002.x. Epub 2009 May 11.

PMID:
19432587
46.

ATP release from non-excitable cells.

Praetorius HA, Leipziger J.

Purinergic Signal. 2009 Dec;5(4):433-46. doi: 10.1007/s11302-009-9146-2. Epub 2009 Mar 20.

47.

Alpha-hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis.

Skals M, Jorgensen NR, Leipziger J, Praetorius HA.

Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):4030-5. doi: 10.1073/pnas.0807044106. Epub 2009 Feb 18.

48.

The essential role of luminal BK channels in distal colonic K+ secretion.

Sörensen MV, Leipziger J.

J Med Invest. 2009;56 Suppl:301.

49.
50.

CFTR - a gatekeeper for duodenal HCO3- secretion.

Leipziger J.

Acta Physiol (Oxf). 2008 Aug;193(4):309. doi: 10.1111/j.1748-1716.2008.01872_1.x. No abstract available.

PMID:
18657239

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