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Items: 31


Lisinopril preserves physical resilience and extends life span in a genotype-specific manner in Drosophila melanogaster.

Gabrawy MM, Campbell S, Carbone MA, Morozova TV, Arya GH, B Turlapati L, Walston JD, Starz-Gaiano M, Everett L, Mackay TFC, Leips J, Abadir PM.

J Gerontol A Biol Sci Med Sci. 2019 Jun 14. pii: glz152. doi: 10.1093/gerona/glz152. [Epub ahead of print]


Pleiotropy, constraint, and modularity in the evolution of life histories: insights from genomic analyses.

Hughes KA, Leips J.

Ann N Y Acad Sci. 2017 Feb;1389(1):76-91. doi: 10.1111/nyas.13256. Epub 2016 Dec 9. Review.


Corrigendum to "Knockdown expression of Syndecan in the fat body impacts nutrient metabolism and the organismal response to environmental stresses in Drosophila melanogaster" [Biochem. Biophys. Res. Commun. (2016) 103-108].

Eveland M, Brokamp GA, Lue CH, Harbison ST, Leips J, De Luca M.

Biochem Biophys Res Commun. 2016 Sep 30;478(4):1798. doi: 10.1016/j.bbrc.2016.09.031. Epub 2016 Sep 11. No abstract available.


Knockdown expression of Syndecan in the fat body impacts nutrient metabolism and the organismal response to environmental stresses in Drosophila melanogaster.

Eveland M, Brokamp GA, Lue CH, Harbison ST, Leips J, De Luca M.

Biochem Biophys Res Commun. 2016 Aug 12;477(1):103-108. doi: 10.1016/j.bbrc.2016.06.027. Epub 2016 Jun 8. Erratum in: Biochem Biophys Res Commun. 2016 Sep 30;478(4):1798.


Development and Assessment of Modules to Integrate Quantitative Skills in Introductory Biology Courses.

Hoffman K, Leupen S, Dowell K, Kephart K, Leips J.

CBE Life Sci Educ. 2016 Summer;15(2). pii: ar14. doi: 10.1187/cbe.15-09-0186.


Variable light environments induce plastic spectral tuning by regional opsin coexpression in the African cichlid fish, Metriaclima zebra.

Dalton BE, Lu J, Leips J, Cronin TW, Carleton KL.

Mol Ecol. 2015 Aug;24(16):4193-204. doi: 10.1111/mec.13312. Epub 2015 Aug 6.


Genome-wide analysis in Drosophila reveals age-specific effects of SNPs on fitness traits.

Durham MF, Magwire MM, Stone EA, Leips J.

Nat Commun. 2014 Jul 8;5:4338. doi: 10.1038/ncomms5338.


Phagocytic ability declines with age in adult Drosophila hemocytes.

Horn L, Leips J, Starz-Gaiano M.

Aging Cell. 2014 Aug;13(4):719-28. doi: 10.1111/acel.12227. Epub 2014 May 14.


Evolution in population parameters: density-dependent selection or density-dependent fitness?

Travis J, Leips J, Rodd FH.

Am Nat. 2013 May;181 Suppl 1:S9-S20. doi: 10.1086/669970. Epub 2013 Feb 25.


The adaptive significance of population differentiation in offspring size of the least killifish, Heterandria formosa.

Leips J, Helen Rodd F, Travis J.

Ecol Evol. 2013 Apr;3(4):948-60. doi: 10.1002/ece3.509. Epub 2013 Mar 5.


Defense traits of larval Drosophila melanogaster exhibit genetically based trade-offs against different species of parasitoids.

Hodges TK, Laskowski KL, Squadrito GL, De Luca M, Leips J.

Evolution. 2013 Mar;67(3):749-60. doi: 10.1111/j.1558-5646.2012.01813.x. Epub 2012 Oct 18.


Genomic basis of aging and life-history evolution in Drosophila melanogaster.

Remolina SC, Chang PL, Leips J, Nuzhdin SV, Hughes KA.

Evolution. 2012 Nov;66(11):3390-403. doi: 10.1111/j.1558-5646.2012.01710.x. Epub 2012 Jun 27.


Age-specific variation in immune response in Drosophila melanogaster has a genetic basis.

Felix TM, Hughes KA, Stone EA, Drnevich JM, Leips J.

Genetics. 2012 Jul;191(3):989-1002. doi: 10.1534/genetics.112.140640. Epub 2012 May 2.


A conserved role for syndecan family members in the regulation of whole-body energy metabolism.

De Luca M, Klimentidis YC, Casazza K, Chambers MM, Cho R, Harbison ST, Jumbo-Lucioni P, Zhang S, Leips J, Fernandez JR.

PLoS One. 2010 Jun 23;5(6):e11286. doi: 10.1371/journal.pone.0011286.


Age- and diet-specific effects of variation at S6 kinase on life history, metabolic, and immune response traits in Drosophila melanogaster.

Cho I, Horn L, Felix TM, Foster L, Gregory G, Starz-Gaiano M, Chambers MM, De Luca M, Leips J.

DNA Cell Biol. 2010 Sep;29(9):473-85. doi: 10.1089/dna.2009.0997.


Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster.

Jumbo-Lucioni P, Ayroles JF, Chambers MM, Jordan KW, Leips J, Mackay TF, De Luca M.

BMC Genomics. 2010 May 11;11:297. doi: 10.1186/1471-2164-11-297.


Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression.

Bunt SK, Yang L, Sinha P, Clements VK, Leips J, Ostrand-Rosenberg S.

Cancer Res. 2007 Oct 15;67(20):10019-26.


Speed-mapping quantitative trait loci using microarrays.

Lai CQ, Leips J, Zou W, Roberts JF, Wollenberg KR, Parnell LD, Zeng ZB, Ordovas JM, Mackay TF.

Nat Methods. 2007 Oct;4(10):839-41. Epub 2007 Sep 16.


Age specificity of inbreeding load in Drosophila melanogaster and implications for the evolution of late-life mortality plateaus.

Reynolds RM, Temiyasathit S, Reedy MM, Ruedi EA, Drnevich JM, Leips J, Hughes KA.

Genetics. 2007 Sep;177(1):587-95. Epub 2007 Jul 29.


Mapping genetic polymorphisms affecting natural variation in Drosophila longevity.

De Luca M, Leips J.

Methods Mol Biol. 2007;371:307-20. Review.


Naturally occurring genetic variation in the age-specific immune response of Drosophila melanogaster.

Lesser KJ, Paiusi IC, Leips J.

Aging Cell. 2006 Aug;5(4):293-5. Epub 2006 Jun 27.


Phenotypic variation and natural selection at catsup, a pleiotropic quantitative trait gene in Drosophila.

Carbone MA, Jordan KW, Lyman RF, Harbison ST, Leips J, Morgan TJ, DeLuca M, Awadalla P, Mackay TF.

Curr Biol. 2006 May 9;16(9):912-9.


Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression.

Bunt SK, Sinha P, Clements VK, Leips J, Ostrand-Rosenberg S.

J Immunol. 2006 Jan 1;176(1):284-90.


Quantitative trait loci with age-specific effects on fecundity in Drosophila melanogaster.

Leips J, Gilligan P, Mackay TF.

Genetics. 2006 Mar;172(3):1595-605. Epub 2005 Nov 4.


Mapping quantitative trait loci affecting variation in Drosophila triacylglycerol storage.

De Luca M, Yi N, Allison DB, Leips J, Ruden DM.

Obes Res. 2005 Sep;13(9):1596-605.


The complex genetic architecture of Drosophila life span.

Leips J, Mackay TF.

Exp Aging Res. 2002 Oct-Dec;28(4):361-90.


High-resolution mapping of quantitative trait loci for sternopleural bristle number in Drosophila melanogaster.

Gurganus MC, Nuzhdin SV, Leips JW, Mackay TF.

Genetics. 1999 Aug;152(4):1585-604.

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