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Items: 1 to 50 of 88

1.

[11C]PIB PET Is Associated with the Brain Biopsy Amyloid-β Load in Subjects Examined for Normal Pressure Hydrocephalus.

Rinne JO, Suotunen T, Rummukainen J, Herukka SK, Nerg O, Koivisto AM, Rauramaa T, Någren K, Hiltunen M, Alafuzoff I, Rinne J, Jääskeläinen JE, Soininen H, Leinonen V.

J Alzheimers Dis. 2019 Jan 21. doi: 10.3233/JAD-180645. [Epub ahead of print]

PMID:
30689567
2.

Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer's Disease.

Marttinen M, Takalo M, Natunen T, Wittrahm R, Gabbouj S, Kemppainen S, Leinonen V, Tanila H, Haapasalo A, Hiltunen M.

Front Neurosci. 2018 Dec 14;12:963. doi: 10.3389/fnins.2018.00963. eCollection 2018. Review.

3.

Copy number loss in SFMBT1 is common among Finnish and Norwegian patients with iNPH.

Korhonen VE, Helisalmi S, Jokinen A, Jokinen I, Lehtola JM, Oinas M, Lönnrot K, Avellan C, Kotkansalo A, Frantzen J, Rinne J, Ronkainen A, Kauppinen M, Junkkari A, Hiltunen M, Soininen H, Kurki M, Jääskeläinen JE, Koivisto AM, Sato H, Kato T, Remes AM, Eide PK, Leinonen V.

Neurol Genet. 2018 Dec 3;4(6):e291. doi: 10.1212/NXG.0000000000000291. eCollection 2018 Dec.

4.

A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology.

Marttinen M, Paananen J, Neme A, Mitra V, Takalo M, Natunen T, Paldanius KMA, Mäkinen P, Bremang M, Kurki MI, Rauramaa T, Leinonen V, Soininen H, Haapasalo A, Pike I, Hiltunen M.

Neurobiol Dis. 2019 Apr;124:454-468. doi: 10.1016/j.nbd.2018.12.009. Epub 2018 Dec 15.

5.

Alterations in mitochondria-endoplasmic reticulum connectivity in human brain biopsies from idiopathic normal pressure hydrocephalus patients.

Leal NS, Dentoni G, Schreiner B, Kämäräinen OP, Partanen N, Herukka SK, Koivisto AM, Hiltunen M, Rauramaa T, Leinonen V, Ankarcrona M.

Acta Neuropathol Commun. 2018 Oct 1;6(1):102. doi: 10.1186/s40478-018-0605-2.

6.

Association of Modic changes with health-related quality of life among patients referred to spine surgery.

Määttä J, Kautiainen H, Leinonen V, Niinimäki J, Järvenpää S, Koskelainen T, Mäkelä P, Pesälä J, Nyyssönen T, Savolainen S, Airaksinen O, Kyllönen E, Cheung KMC, Karppinen J.

Scand J Pain. 2014 Jan 1;5(1):36-40. doi: 10.1016/j.sjpain.2013.08.003.

PMID:
29913663
7.

S-[18F]THK-5117-PET and [11C]PIB-PET Imaging in Idiopathic Normal Pressure Hydrocephalus in Relation to Confirmed Amyloid-β Plaques and Tau in Brain Biopsies.

Leinonen V, Rauramaa T, Johansson J, Bottelbergs A, Tesseur I, van der Ark P, Pemberton D, Koivisto AM, Jääskeläinen JE, Hiltunen M, Herukka SK, Blennow K, Zetterberg H, Jokinen P, Rokka J, Helin S, Haaparanta-Solin M, Solin O, Okamura N, Kolb HC, Rinne JO.

J Alzheimers Dis. 2018;64(1):171-179. doi: 10.3233/JAD-180071.

PMID:
29865068
8.

Long-Term Outcome of Spinal Cord Stimulation in Failed Back Surgery Syndrome: 20 Years of Experience With 224 Consecutive Patients.

Nissen M, Ikäheimo TM, Huttunen J, Leinonen V, von Und Zu Fraunberg M.

Neurosurgery. 2018 May 21. doi: 10.1093/neuros/nyy194. [Epub ahead of print]

PMID:
29788145
9.

Prevalence of Schizophrenia in Idiopathic Normal Pressure Hydrocephalus.

Vanhala V, Junkkari A, Korhonen VE, Kurki MI, Hiltunen M, Rauramaa T, Nerg O, Koivisto AM, Remes AM, Perälä J, Suvisaari J, Lehto SM, Viinamäki H, Soininen H, Jääskeläinen JE, Leinonen V.

Neurosurgery. 2018 May 8. doi: 10.1093/neuros/nyy147. [Epub ahead of print]

PMID:
29741669
10.

Sushi repeat-containing protein X-linked 2: A novel phylogenetically conserved hypothalamo-pituitary protein.

Anwer M, Bolkvadze T, Ndode-Ekane XE, Puhakka N, Rauramaa T, Leinonen V, van Vliet EA, Swaab DF, Haapasalo A, Leskelä S, Bister N, Malm T, Carlson S, Aronica E, Pitkänen A.

J Comp Neurol. 2018 Aug 1;526(11):1806-1819. doi: 10.1002/cne.24449. Epub 2018 May 1.

PMID:
29663392
11.

Interrelationship between the Levels of C9orf72 and Amyloid-β Protein Precursor and Amyloid-β in Human Cells and Brain Samples.

Leskelä S, Takalo M, Marttinen M, Huber N, Paananen J, Mitra V, Rauramaa T, Mäkinen P, Leinonen V, Soininen H, Pike I, Remes AM, Hiltunen M, Haapasalo A.

J Alzheimers Dis. 2018;62(1):269-278. doi: 10.3233/JAD-170362.

PMID:
29439323
12.

Incidence, Comorbidities, and Mortality in Idiopathic Normal Pressure Hydrocephalus.

Pyykkö OT, Nerg O, Niskasaari HM, Niskasaari T, Koivisto AM, Hiltunen M, Pihlajamäki J, Rauramaa T, Kojoukhova M, Alafuzoff I, Soininen H, Jääskeläinen JE, Leinonen V.

World Neurosurg. 2018 Apr;112:e624-e631. doi: 10.1016/j.wneu.2018.01.107. Epub 2018 Jan 31.

PMID:
29374607
13.

Cerebrospinal fluid circulation and hydrocephalus.

Leinonen V, Vanninen R, Rauramaa T.

Handb Clin Neurol. 2017;145:39-50. doi: 10.1016/B978-0-12-802395-2.00005-5. Review.

PMID:
28987185
14.

Raised intracranial pressure and brain edema.

Leinonen V, Vanninen R, Rauramaa T.

Handb Clin Neurol. 2017;145:25-37. doi: 10.1016/B978-0-12-802395-2.00004-3. Review.

PMID:
28987174
15.

Alzheimer's Disease-Related Polymorphisms in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus.

Huovinen J, Helisalmi S, Paananen J, Laiterä T, Kojoukhova M, Sutela A, Vanninen R, Laitinen M, Rauramaa T, Koivisto AM, Remes AM, Soininen H, Kurki M, Haapasalo A, Jääskeläinen JE, Hiltunen M, Leinonen V.

J Alzheimers Dis. 2017;60(3):1077-1085. doi: 10.3233/JAD-170583.

PMID:
28984604
16.

Abstracts from Hydrocephalus 2016.

Adam A, Robison J, Lu J, Jose R, Badran N, Vivas-Buitrago T, Rigamonti D, Sattar A, Omoush O, Hammad M, Dawood M, Maghaslah M, Belcher T, Carson K, Hoffberger J, Jusué Torres I, Foley S, Yasar S, Thai QA, Wemmer J, Klinge P, Al-Mutawa L, Al-Ghamdi H, Carson KA, Asgari M, de Zélicourt D, Kurtcuoglu V, Garnotel S, Salmon S, Balédent O, Lokossou A, Page G, Balardy L, Czosnyka Z, Payoux P, Schmidt EA, Zitoun M, Sevestre MA, Alperin N, Baudracco I, Craven C, Matloob S, Thompson S, Haylock Vize P, Thorne L, Watkins LD, Toma AK, Bechter K, Pong AC, Jugé L, Bilston LE, Cheng S, Bradley W, Hakim F, Ramón JF, Cárdenas MF, Davidson JS, García C, González D, Bermúdez S, Useche N, Mejía JA, Mayorga P, Cruz F, Martinez C, Matiz MC, Vallejo M, Ghotme K, Soto HA, Riveros D, Buitrago A, Mora M, Murcia L, Bermudez S, Cohen D, Dasgupta D, Curtis C, Domínguez L, Remolina AJ, Grijalba MA, Whitehouse KJ, Edwards RJ, Eleftheriou A, Lundin F, Fountas KN, Kapsalaki EZ, Smisson HF, Robinson JS, Fritsch MJ, Arouk W, Garzon M, Kang M, Sandhu K, Baghawatti D, Aquilina K, James G, Thompson D, Gehlen M, Schmid Daners M, Eklund A, Malm J, Gomez D, Guerra M, Jara M, Flores M, Vío K, Moreno I, Rodríguez S, Ortega E, Rodríguez EM, McAllister JP, Guerra MM, Morales DM, Sival D, Jimenez A, Limbrick DD, Ishikawa M, Yamada S, Yamamoto K, Junkkari A, Häyrinen A, Rauramaa T, Sintonen H, Nerg O, Koivisto AM, Roine RP, Viinamäki H, Soininen H, Luikku A, Jääskeläinen JE, Leinonen V, Kehler U, Lilja-Lund O, Kockum K, Larsson EM, Riklund K, Söderström L, Hellström P, Laurell K, Kojoukhova M, Sutela A, Vanninen R, Vanha KI, Timonen M, Rummukainen J, Korhonen V, Helisalmi S, Solje E, Remes AM, Huovinen J, Paananen J, Hiltunen M, Kurki M, Martin B, Loth F, Luciano M, Luikku AJ, Hall A, Herukka SK, Mattila J, Lötjönen J, Alafuzoff I, Jurjević I, Miyajima M, Nakajima M, Murai H, Shin T, Kawaguchi D, Akiba C, Ogino I, Karagiozov K, Arai H, Reis RC, Teixeira MJ, Valêncio CG, da Vigua D, Almeida-Lopes L, Mancini MW, Pinto FCG, Maykot RH, Calia G, Tornai J, Silvestre SSS, Mendes G, Sousa V, Bezerra B, Dutra P, Modesto P, Oliveira MF, Petitto CE, Pulhorn H, Chandran A, McMahon C, Rao AS, Jumaly M, Solomon D, Moghekar A, Relkin N, Hamilton M, Katzen H, Williams M, Bach T, Zuspan S, Holubkov R, Rigamonti A, Clemens G, Sharkey P, Sanyal A, Sankey E, Rigamonti K, Naqvi S, Hung A, Schmidt E, Ory-Magne F, Gantet P, Guenego A, Januel AC, Tall P, Fabre N, Mahieu L, Cognard C, Gray L, Buttner-Ennever JA, Takagi K, Onouchi K, Thompson SD, Thorne LD, Tully HM, Wenger TL, Kukull WA, Doherty D, Dobyns WB, Moran D, Vakili S, Patel MA, Elder B, Goodwin CR, Crawford JA, Pletnikov MV, Xu J, Blitz A, Herzka DA, Guerrero-Cazares H, Quiñones-Hinojosa A, Mori S, Saavedra P, Treviño H, Maitani K, Ziai WC, Eslami V, Nekoovaght-Tak S, Dlugash R, Yenokyan G, McBee N, Hanley DF.

Fluids Barriers CNS. 2017 Jun 7;14(Suppl 1):15. doi: 10.1186/s12987-017-0054-5. No abstract available.

17.

Why Does the Health-Related Quality of Life in Idiopathic Normal-Pressure Hydrocephalus Fail to Improve Despite the Favorable Clinical Outcome?

Junkkari A, Roine RP, Luikku A, Rauramaa T, Sintonen H, Nerg O, Koivisto AM, Häyrinen A, Viinamäki H, Soininen H, Jääskeläinen JE, Leinonen V.

World Neurosurg. 2017 Dec;108:356-366. doi: 10.1016/j.wneu.2017.08.170. Epub 2017 Sep 5.

PMID:
28887286
18.

Immunohistochemical Characterization and Sensitivity to Human Adenovirus Serotypes 3, 5, and 11p of New Cell Lines Derived from Human Diffuse Grade II to IV Gliomas.

Niittykoski M, von Und Zu Fraunberg M, Martikainen M, Rauramaa T, Immonen A, Koponen S, Leinonen V, Vähä-Koskela M, Zhang Q, Kühnel F, Mei YF, Ylä-Herttuala S, Jääskeläinen JE, Hinkkanen A.

Transl Oncol. 2017 Oct;10(5):772-779. doi: 10.1016/j.tranon.2017.07.002. Epub 2017 Aug 4.

19.

Frontotemporal dementia as a comorbidity to idiopathic normal pressure hydrocephalus (iNPH): a short review of literature and an unusual case.

Korhonen VE, Solje E, Suhonen NM, Rauramaa T, Vanninen R, Remes AM, Leinonen V.

Fluids Barriers CNS. 2017 Apr 19;14(1):10. doi: 10.1186/s12987-017-0060-7. Review.

20.

Rate and Risk Factors for Shunt Revision in Pediatric Patients with Hydrocephalus-A Population-Based Study.

Tervonen J, Leinonen V, Jääskeläinen JE, Koponen S, Huttunen TJ.

World Neurosurg. 2017 May;101:615-622. doi: 10.1016/j.wneu.2017.02.030. Epub 2017 Feb 14. Review.

PMID:
28213196
21.

Associations of intracranial pressure with brain biopsy, radiological findings, and shunt surgery outcome in patients with suspected idiopathic normal pressure hydrocephalus.

Kojoukhova M, Vanha KI, Timonen M, Koivisto AM, Nerg O, Rummukainen J, Rauramaa T, Vanninen R, Jääskeläinen JE, Sutela A, Leinonen V.

Acta Neurochir (Wien). 2017 Jan;159(1):51-61. doi: 10.1007/s00701-016-3025-8. Epub 2016 Nov 23.

PMID:
27878614
22.

Implantable RF-coil with multiple electrodes for long-term EEG-fMRI monitoring in rodents.

Pirttimäki T, Salo RA, Shatillo A, Kettunen MI, Paasonen J, Sierra A, Jokivarsi K, Leinonen V, Andrade P, Quittek S, Pitkänen A, Gröhn O.

J Neurosci Methods. 2016 Dec 1;274:154-163. doi: 10.1016/j.jneumeth.2016.10.014. Epub 2016 Oct 21.

23.

Effects of Alzheimer's Disease-Associated Risk Loci on Amyloid-β Accumulation in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients.

Laiterä T, Paananen J, Helisalmi S, Sarajärvi T, Huovinen J, Laitinen M, Rauramaa T, Alafuzoff I, Remes AM, Soininen H, Haapasalo A, Jääskeläinen JE, Leinonen V, Hiltunen M.

J Alzheimers Dis. 2017;55(3):995-1003.

PMID:
27802227
24.

Multimodal analysis to predict shunt surgery outcome of 284 patients with suspected idiopathic normal pressure hydrocephalus.

Luikku AJ, Hall A, Nerg O, Koivisto AM, Hiltunen M, Helisalmi S, Herukka SK, Sutela A, Kojoukhova M, Mattila J, Lötjönen J, Rummukainen J, Alafuzoff I, Jääskeläinen JE, Remes AM, Soininen H, Leinonen V.

Acta Neurochir (Wien). 2016 Dec;158(12):2311-2319. Epub 2016 Oct 14.

PMID:
27743250
25.

Health-related quality-of-life outcome in patients with idiopathic normal-pressure hydrocephalus - a 1-year follow-up study.

Junkkari A, Häyrinen A, Rauramaa T, Sintonen H, Nerg O, Koivisto AM, Roine RP, Viinamäki H, Soininen H, Luikku A, Jääskeläinen JE, Leinonen V.

Eur J Neurol. 2017 Jan;24(1):58-66. doi: 10.1111/ene.13130. Epub 2016 Sep 19.

PMID:
27647684
26.

Risk of Shunting After Aneurysmal Subarachnoid Hemorrhage: A Collaborative Study and Initiation of a Consortium.

Adams H, Ban VS, Leinonen V, Aoun SG, Huttunen J, Saavalainen T, Lindgren A, Frosen J, Fraunberg M, Koivisto T, Hernesniemi J, Welch BG, Jaaskelainen JE, Huttunen TJ.

Stroke. 2016 Oct;47(10):2488-96. doi: 10.1161/STROKEAHA.116.013739. Epub 2016 Sep 15.

PMID:
27633019
27.

Familial idiopathic normal pressure hydrocephalus.

Huovinen J, Kastinen S, Komulainen S, Oinas M, Avellan C, Frantzen J, Rinne J, Ronkainen A, Kauppinen M, Lönnrot K, Perola M, Pyykkö OT, Koivisto AM, Remes AM, Soininen H, Hiltunen M, Helisalmi S, Kurki M, Jääskeläinen JE, Leinonen V.

J Neurol Sci. 2016 Sep 15;368:11-8. doi: 10.1016/j.jns.2016.06.052. Epub 2016 Jun 25.

PMID:
27538594
28.

[Emergency craniotomies at the North Karelia Central Hospital in 2006 to 2014].

Aro E, Jääskeläinen JE, Reinikainen M, Leinonen V, Hakala T.

Duodecim. 2016;132(9):858-65. Finnish.

PMID:
27319084
29.

SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.

Kurkinen KM, Marttinen M, Turner L, Natunen T, Mäkinen P, Haapalinna F, Sarajärvi T, Gabbouj S, Kurki M, Paananen J, Koivisto AM, Rauramaa T, Leinonen V, Tanila H, Soininen H, Lucas FR, Haapasalo A, Hiltunen M.

J Cell Sci. 2016 Jun 1;129(11):2224-38. doi: 10.1242/jcs.185215. Epub 2016 Apr 15.

30.

Selling vs. non-selling neuro-oncology research cohorts and manuscripts in the eyes of a grumpy reviewer after 2,000 reviews.

Leinonen V, Jääskeläinen JE.

Acta Neurochir (Wien). 2017 Jan;159(1):3-6. doi: 10.1007/s00701-016-2787-3. Epub 2016 Apr 7. No abstract available.

PMID:
27055528
31.

High Risk of Dementia in Ventricular Enlargement with Normal Pressure Hydrocephalus Related Symptoms1.

Koivisto AM, Kurki MI, Alafuzoff I, Sutela A, Rummukainen J, Savolainen S, Vanninen R, Jääskeläinen JE, Soininen H, Leinonen V.

J Alzheimers Dis. 2016 Mar 22;52(2):497-507. doi: 10.3233/JAD-150909.

PMID:
27031474
32.

Sub-classification based specific movement control exercises are superior to general exercise in sub-acute low back pain when both are combined with manual therapy: A randomized controlled trial.

Lehtola V, Luomajoki H, Leinonen V, Gibbons S, Airaksinen O.

BMC Musculoskelet Disord. 2016 Mar 22;17:135. doi: 10.1186/s12891-016-0986-y.

33.

Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.

Natunen T, Takalo M, Kemppainen S, Leskelä S, Marttinen M, Kurkinen KMA, Pursiheimo JP, Sarajärvi T, Viswanathan J, Gabbouj S, Solje E, Tahvanainen E, Pirttimäki T, Kurki M, Paananen J, Rauramaa T, Miettinen P, Mäkinen P, Leinonen V, Soininen H, Airenne K, Tanzi RE, Tanila H, Haapasalo A, Hiltunen M.

Neurobiol Dis. 2016 Jan;85:187-205. doi: 10.1016/j.nbd.2015.11.005. Epub 2015 Nov 10.

PMID:
26563932
34.

The Expression of Transthyretin and Amyloid-β Protein Precursor is Altered in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients.

Laiterä T, Kurki MI, Pursiheimo JP, Zetterberg H, Helisalmi S, Rauramaa T, Alafuzoff I, Remes AM, Soininen H, Haapasalo A, Jääskeläinen JE, Hiltunen M, Leinonen V.

J Alzheimers Dis. 2015;48(4):959-68. doi: 10.3233/JAD-150268.

PMID:
26444765
35.

Genetic Variation in δ-Opioid Receptor Associates with Increased β- and γ-Secretase Activity in the Late Stages of Alzheimer's Disease.

Sarajärvi T, Marttinen M, Natunen T, Kauppinen T, Mäkinen P, Helisalmi S, Laitinen M, Rauramaa T, Leinonen V, Petäjä-Repo U, Soininen H, Haapasalo A, Hiltunen M.

J Alzheimers Dis. 2015;48(2):507-16. doi: 10.3233/JAD-150221.

PMID:
26402014
36.

[Update on Current Care Guideline: Low back pain].

Pohjolainen T, Leinonen V, Frantén J, Haanpää M, Jousimaa J, Karppinen J, Kuukkanen T, Luoma K, Salmenkivi J, Osterman H, Malmivaara A; Päivitystiivistelmä.

Duodecim. 2015;131(1):92-4. Review. Finnish.

PMID:
26245063
37.

Chasing the Effects of Pre-Analytical Confounders - A Multicenter Study on CSF-AD Biomarkers.

Leitão MJ, Baldeiras I, Herukka SK, Pikkarainen M, Leinonen V, Simonsen AH, Perret-Liaudet A, Fourier A, Quadrio I, Veiga PM, de Oliveira CR.

Front Neurol. 2015 Jul 8;6:153. doi: 10.3389/fneur.2015.00153. eCollection 2015.

38.

Feasibility of radiological markers in idiopathic normal pressure hydrocephalus.

Kojoukhova M, Koivisto AM, Korhonen R, Remes AM, Vanninen R, Soininen H, Jääskeläinen JE, Sutela A, Leinonen V.

Acta Neurochir (Wien). 2015 Oct;157(10):1709-18; discussion 1719. doi: 10.1007/s00701-015-2503-8. Epub 2015 Jul 21.

PMID:
26190755
39.

Health-related quality of life in patients with idiopathic normal pressure hydrocephalus.

Junkkari A, Sintonen H, Nerg O, Koivisto AM, Roine RP, Viinamäki H, Soininen H, Jääskeläinen JE, Leinonen V.

Eur J Neurol. 2015 Oct;22(10):1391-9. doi: 10.1111/ene.12755. Epub 2015 Jun 24.

PMID:
26104064
40.

The effect of decompressive surgery on lumbar paraspinal and biceps brachii muscle function and movement perception in lumbar spinal stenosis: a 2-year follow-up.

Kääriäinen T, Taimela S, Aalto T, Kröger H, Herno A, Turunen V, Savolainen S, Kankaanpää M, Airaksinen O, Leinonen V.

Eur Spine J. 2016 Mar;25(3):789-94. doi: 10.1007/s00586-015-4036-5. Epub 2015 May 27.

PMID:
26014807
41.

Analysis of disruptive events and precarious situations caused by interaction with neurosurgical microscope.

Eivazi S, Afkari H, Bednarik R, Leinonen V, Tukiainen M, Jääskeläinen JE.

Acta Neurochir (Wien). 2015 Jul;157(7):1147-54. doi: 10.1007/s00701-015-2433-5. Epub 2015 May 12.

PMID:
25962996
42.

Amyloid-β and Tau Dynamics in Human Brain Interstitial Fluid in Patients with Suspected Normal Pressure Hydrocephalus.

Herukka SK, Rummukainen J, Ihalainen J, von Und Zu Fraunberg M, Koivisto AM, Nerg O, Puli LK, Seppälä TT, Zetterberg H, Pyykkö OT, Helisalmi S, Tanila H, Alafuzoff I, Hiltunen M, Rinne J, Soininen H, Jääskeläinen JE, Leinonen V.

J Alzheimers Dis. 2015;46(1):261-9. doi: 10.3233/JAD-142862.

PMID:
25720406
43.

Visually assessed severity of lumbar spinal canal stenosis is paradoxically associated with leg pain and objective walking ability.

Kuittinen P, Sipola P, Saari T, Aalto TJ, Sinikallio S, Savolainen S, Kröger H, Turunen V, Leinonen V, Airaksinen O.

BMC Musculoskelet Disord. 2014 Oct 16;15:348. doi: 10.1186/1471-2474-15-348.

44.

Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.

Martiskainen H, Viswanathan J, Nykänen NP, Kurki M, Helisalmi S, Natunen T, Sarajärvi T, Kurkinen KM, Pursiheimo JP, Rauramaa T, Alafuzoff I, Jääskeläinen JE, Leinonen V, Soininen H, Haapasalo A, Huttunen HJ, Hiltunen M.

Neurobiol Aging. 2015 Feb;36(2):1221.e15-28. doi: 10.1016/j.neurobiolaging.2014.09.003. Epub 2014 Sep 6.

PMID:
25281018
45.

Association between bone mineral density and lumbar disc degeneration.

Salo S, Leinonen V, Rikkonen T, Vainio P, Marttila J, Honkanen R, Tuppurainen M, Kröger H, Sirola J.

Maturitas. 2014 Dec;79(4):449-55. doi: 10.1016/j.maturitas.2014.09.003. Epub 2014 Sep 22.

PMID:
25266266
46.

Preoperative MRI findings predict two-year postoperative clinical outcome in lumbar spinal stenosis.

Kuittinen P, Sipola P, Leinonen V, Saari T, Sinikallio S, Savolainen S, Kröger H, Turunen V, Airaksinen O, Aalto T.

PLoS One. 2014 Sep 17;9(9):e106404. doi: 10.1371/journal.pone.0106404. eCollection 2014.

47.

Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach.

Martiskainen H, Helisalmi S, Viswanathan J, Kurki M, Hall A, Herukka SK, Sarajärvi T, Natunen T, Kurkinen KM, Huovinen J, Mäkinen P, Laitinen M, Koivisto AM, Mattila KM, Lehtimäki T, Remes AM, Leinonen V, Haapasalo A, Soininen H, Hiltunen M.

J Alzheimers Dis. 2015;43(2):565-73. doi: 10.3233/JAD-140777.

PMID:
25096612
48.

Correlation of lateral stenosis in MRI with symptoms, walking capacity and EMG findings in patients with surgically confirmed lateral lumbar spinal canal stenosis.

Kuittinen P, Sipola P, Aalto TJ, Määttä S, Parviainen A, Saari T, Sinikallio S, Savolainen S, Turunen V, Kröger H, Airaksinen O, Leinonen V.

BMC Musculoskelet Disord. 2014 Jul 23;15:247. doi: 10.1186/1471-2474-15-247.

49.

Diagnostic effectiveness of quantitative [¹⁸F]flutemetamol PET imaging for detection of fibrillar amyloid β using cortical biopsy histopathology as the standard of truth in subjects with idiopathic normal pressure hydrocephalus.

Leinonen V, Rinne JO, Wong DF, Wolk DA, Trojanowski JQ, Sherwin PF, Smith A, Heurling K, Su M, Grachev ID.

Acta Neuropathol Commun. 2014 Apr 22;2:46. doi: 10.1186/2051-5960-2-46.

50.

High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status.

Takalo M, Haapasalo A, Martiskainen H, Kurkinen KM, Koivisto H, Miettinen P, Khandelwal VK, Kemppainen S, Kaminska D, Mäkinen P, Leinonen V, Pihlajamäki J, Soininen H, Laakso M, Tanila H, Hiltunen M.

J Nutr Biochem. 2014 Jun;25(6):634-41. doi: 10.1016/j.jnutbio.2014.02.003. Epub 2014 Mar 12.

PMID:
24746833

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