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Items: 24

1.

Viral Factors Important for Efficient Replication of Influenza A Viruses in Cells of the Central Nervous System.

Siegers JY, van de Bildt MWG, Lin Z, Leijten LM, Lavrijssen RAM, Bestebroer T, Spronken MIJ, De Zeeuw CI, Gao Z, Schrauwen EJA, Kuiken T, van Riel D.

J Virol. 2019 May 15;93(11). pii: e02273-18. doi: 10.1128/JVI.02273-18. Print 2019 Jun 1.

2.

1918 H1N1 Influenza Virus Replicates and Induces Proinflammatory Cytokine Responses in Extrarespiratory Tissues of Ferrets.

de Wit E, Siegers JY, Cronin JM, Weatherman S, van den Brand JM, Leijten LM, van Run P, Begeman L, van den Ham HJ, Andeweg AC, Bushmaker T, Scott DP, Saturday G, Munster VJ, Feldmann H, van Riel D.

J Infect Dis. 2018 Mar 28;217(8):1237-1246. doi: 10.1093/infdis/jiy003.

3.

Proinflammatory Cytokine Responses in Extra-Respiratory Tissues During Severe Influenza.

Short KR, Veeris R, Leijten LM, van den Brand JM, Jong VL, Stittelaar K, Osterhaus ADME, Andeweg A, van Riel D.

J Infect Dis. 2017 Oct 17;216(7):829-833. doi: 10.1093/infdis/jix281.

PMID:
28973159
4.

Vaccination Is More Effective Than Prophylactic Oseltamivir in Preventing CNS Invasion by H5N1 Virus via the Olfactory Nerve.

Siegers JY, van den Brand JM, Leijten LM, van de Bildt MM, van Run PR, van Amerongen G, Stittelaar KJ, Koopmans MP, Osterhaus AD, Kuiken T, van Riel D.

J Infect Dis. 2016 Aug 15;214(4):516-24. doi: 10.1093/infdis/jiw123. Epub 2016 Apr 1.

PMID:
27448390
5.

Evolutionary origins of hepatitis A virus in small mammals.

Drexler JF, Corman VM, Lukashev AN, van den Brand JM, Gmyl AP, Brünink S, Rasche A, Seggewiβ N, Feng H, Leijten LM, Vallo P, Kuiken T, Dotzauer A, Ulrich RG, Lemon SM, Drosten C; Hepatovirus Ecology Consortium.

Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15190-5. doi: 10.1073/pnas.1516992112. Epub 2015 Nov 2.

6.

Evidence for influenza virus CNS invasion along the olfactory route in an immunocompromised infant.

van Riel D, Leijten LM, Verdijk RM, GeurtsvanKessel C, van der Vries E, van Rossum AM, Osterhaus AD, Kuiken T.

J Infect Dis. 2014 Aug 1;210(3):419-23. doi: 10.1093/infdis/jiu097. Epub 2014 Feb 18.

PMID:
24550441
7.

Novel avian-origin influenza A (H7N9) virus attachment to the respiratory tract of five animal models.

Siegers JY, Short KR, Leijten LM, de Graaf M, Spronken MI, Schrauwen EJ, Marshall N, Lowen AC, Gabriel G, Osterhaus AD, Kuiken T, van Riel D.

J Virol. 2014 Apr;88(8):4595-9. doi: 10.1128/JVI.03190-13. Epub 2014 Jan 29.

8.

Bats carry pathogenic hepadnaviruses antigenically related to hepatitis B virus and capable of infecting human hepatocytes.

Drexler JF, Geipel A, König A, Corman VM, van Riel D, Leijten LM, Bremer CM, Rasche A, Cottontail VM, Maganga GD, Schlegel M, Müller MA, Adam A, Klose SM, Carneiro AJ, Stöcker A, Franke CR, Gloza-Rausch F, Geyer J, Annan A, Adu-Sarkodie Y, Oppong S, Binger T, Vallo P, Tschapka M, Ulrich RG, Gerlich WH, Leroy E, Kuiken T, Glebe D, Drosten C.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16151-6. doi: 10.1073/pnas.1308049110. Epub 2013 Sep 16.

9.

Novel avian-origin influenza A (H7N9) virus attaches to epithelium in both upper and lower respiratory tract of humans.

van Riel D, Leijten LME, de Graaf M, Siegers JY, Short KR, Spronken MIJ, Schrauwen EJA, Fouchier RAM, Osterhaus ADME, Kuiken T.

Am J Pathol. 2013 Oct;183(4):1137-1143. doi: 10.1016/j.ajpath.2013.06.011. Epub 2013 Sep 10.

10.

Decrease of virus receptors during highly pathogenic H5N1 virus infection in humans and other mammals.

van Riel D, Leijten LM, Kochs G, Osterhaus ADME, Kuiken T.

Am J Pathol. 2013 Nov;183(5):1382-1389. doi: 10.1016/j.ajpath.2013.07.004. Epub 2013 Aug 27.

PMID:
23993779
11.

Evidence for novel hepaciviruses in rodents.

Drexler JF, Corman VM, Müller MA, Lukashev AN, Gmyl A, Coutard B, Adam A, Ritz D, Leijten LM, van Riel D, Kallies R, Klose SM, Gloza-Rausch F, Binger T, Annan A, Adu-Sarkodie Y, Oppong S, Bourgarel M, Rupp D, Hoffmann B, Schlegel M, Kümmerer BM, Krüger DH, Schmidt-Chanasit J, Setién AA, Cottontail VM, Hemachudha T, Wacharapluesadee S, Osterrieder K, Bartenschlager R, Matthee S, Beer M, Kuiken T, Reusken C, Leroy EM, Ulrich RG, Drosten C.

PLoS Pathog. 2013;9(6):e1003438. doi: 10.1371/journal.ppat.1003438. Epub 2013 Jun 20.

12.

Tissue tropism and pathology of natural influenza virus infection in black-headed gulls (Chroicocephalus ridibundus).

Höfle U, Van de Bildt MW, Leijten LM, Van Amerongen G, Verhagen JH, Fouchier RA, Osterhaus AD, Kuiken T.

Avian Pathol. 2012 Dec;41(6):547-53. doi: 10.1080/03079457.2012.744447.

PMID:
23237367
13.

The multibasic cleavage site in H5N1 virus is critical for systemic spread along the olfactory and hematogenous routes in ferrets.

Schrauwen EJ, Herfst S, Leijten LM, van Run P, Bestebroer TM, Linster M, Bodewes R, Kreijtz JH, Rimmelzwaan GF, Osterhaus AD, Fouchier RA, Kuiken T, van Riel D.

J Virol. 2012 Apr;86(7):3975-84. doi: 10.1128/JVI.06828-11. Epub 2012 Jan 25.

14.

Modification of the ferret model for pneumonia from seasonal human influenza A virus infection.

van den Brand JM, Stittelaar KJ, Leijten LM, van Amerongen G, Simon JH, Osterhaus AD, Kuiken T.

Vet Pathol. 2012 May;49(3):562-8. doi: 10.1177/0300985811429812. Epub 2012 Jan 18.

PMID:
22262355
15.

Marked endotheliotropism of highly pathogenic avian influenza virus H5N1 following intestinal inoculation in cats.

Reperant LA, van de Bildt MW, van Amerongen G, Leijten LM, Watson S, Palser A, Kellam P, Eissens AC, Frijlink HW, Osterhaus AD, Kuiken T.

J Virol. 2012 Jan;86(2):1158-65. doi: 10.1128/JVI.06375-11. Epub 2011 Nov 16.

16.

Multidrug resistant 2009 A/H1N1 influenza clinical isolate with a neuraminidase I223R mutation retains its virulence and transmissibility in ferrets.

van der Vries E, Veldhuis Kroeze EJ, Stittelaar KJ, Linster M, Van der Linden A, Schrauwen EJ, Leijten LM, van Amerongen G, Schutten M, Kuiken T, Osterhaus AD, Fouchier RA, Boucher CA, Herfst S.

PLoS Pathog. 2011 Sep;7(9):e1002276. doi: 10.1371/journal.ppat.1002276. Epub 2011 Sep 29.

17.

Highly pathogenic avian influenza virus H5N1 infects alveolar macrophages without virus production or excessive TNF-alpha induction.

van Riel D, Leijten LM, van der Eerden M, Hoogsteden HC, Boven LA, Lambrecht BN, Osterhaus AD, Kuiken T.

PLoS Pathog. 2011 Jun;7(6):e1002099. doi: 10.1371/journal.ppat.1002099. Epub 2011 Jun 23.

18.

Distinct severe acute respiratory syndrome coronavirus-induced acute lung injury pathways in two different nonhuman primate species.

Smits SL, van den Brand JM, de Lang A, Leijten LM, van Ijcken WF, van Amerongen G, Osterhaus AD, Andeweg AC, Haagmans BL.

J Virol. 2011 May;85(9):4234-45. doi: 10.1128/JVI.02395-10. Epub 2011 Feb 16.

19.

Experimental pandemic (H1N1) 2009 virus infection of cats.

van den Brand JM, Stittelaar KJ, van Amerongen G, van de Bildt MW, Leijten LM, Kuiken T, Osterhaus AD.

Emerg Infect Dis. 2010 Nov;16(11):1745-7. doi: 10.3201/eid1611.100845.

20.

Seasonal and pandemic human influenza viruses attach better to human upper respiratory tract epithelium than avian influenza viruses.

van Riel D, den Bakker MA, Leijten LM, Chutinimitkul S, Munster VJ, de Wit E, Rimmelzwaan GF, Fouchier RA, Osterhaus AD, Kuiken T.

Am J Pathol. 2010 Apr;176(4):1614-8. doi: 10.2353/ajpath.2010.090949. Epub 2010 Feb 18.

21.

Exacerbated innate host response to SARS-CoV in aged non-human primates.

Smits SL, de Lang A, van den Brand JM, Leijten LM, van IJcken WF, Eijkemans MJ, van Amerongen G, Kuiken T, Andeweg AC, Osterhaus AD, Haagmans BL.

PLoS Pathog. 2010 Feb 5;6(2):e1000756. doi: 10.1371/journal.ppat.1000756.

22.

Chorionic gonadotropin up-regulates long pentraxin 3 expression in myeloid cells.

Wan H, van Helden-Meeuwsen CG, Garlanda C, Leijten LM, Maina V, Khan NA, Drexhage HA, Mantovani A, Benner R, Versnel MA.

J Leukoc Biol. 2008 Nov;84(5):1346-52. doi: 10.1189/jlb.0108067. Epub 2008 Aug 6.

PMID:
18685085
23.

Chorionic gonadotropin induces dendritic cells to express a tolerogenic phenotype.

Wan H, Versnel MA, Leijten LM, van Helden-Meeuwsen CG, Fekkes D, Leenen PJ, Khan NA, Benner R, Kiekens RC.

J Leukoc Biol. 2008 Apr;83(4):894-901. doi: 10.1189/jlb.0407258. Epub 2008 Jan 2.

PMID:
18171698
24.

Functional genomics highlights differential induction of antiviral pathways in the lungs of SARS-CoV-infected macaques.

de Lang A, Baas T, Teal T, Leijten LM, Rain B, Osterhaus AD, Haagmans BL, Katze MG.

PLoS Pathog. 2007 Aug 10;3(8):e112.

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