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Protocol for a multi-centre randomised controlled stand-alone feasibility trial to assess potential effectiveness and cost-effectiveness of digital hearing aids in patients with tinnitus and hearing loss (the HUSH trial).

Haines RH, White J, Meakin G, Tan W, Hepburn T, Leighton P, Theriou C, Stockdale D, Almey C, Nicholson R, Hall DA, Sereda M.

Pilot Feasibility Stud. 2020 Mar 27;6:41. doi: 10.1186/s40814-020-00582-5. eCollection 2020.


Use of a double-J stent during ex vivo normothermic machine perfusion of human kidneys.

Leighton P, Hosgood SA, Butler AJ, Nicholson ML.

Am J Transplant. 2020 Mar 13. doi: 10.1111/ajt.15848. [Epub ahead of print]


Amyloid-β precursor protein mutant zebrafish exhibit seizure susceptibility that depends on prion protein.

Kanyo R, Leighton PLA, Neil GJ, Locskai LF, Allison WT.

Exp Neurol. 2020 Jun;328:113283. doi: 10.1016/j.expneurol.2020.113283. Epub 2020 Mar 9.


Contamination in complex healthcare trials: the falls in care homes (FinCH) study experience.

Robinson K, Allen F, Darby J, Fox C, Gordon AL, Horne JC, Leighton P, Sims E, Logan PA.

BMC Med Res Methodol. 2020 Feb 27;20(1):46. doi: 10.1186/s12874-020-00925-z.


Evaluation of fluralaner as an oral acaricide to reduce tick infestation in a wild rodent reservoir of Lyme disease.

Pelletier J, Rocheleau JP, Aenishaenslin C, Beaudry F, Dimitri Masson G, Lindsay LR, Ogden NH, Bouchard C, Leighton PA.

Parasit Vectors. 2020 Feb 13;13(1):73. doi: 10.1186/s13071-020-3932-7.


Expression of human lambda expands the repertoire of OmniChickens.

Ching KH, Berg K, Morales J, Pedersen D, Harriman WD, Abdiche YN, Leighton PA.

PLoS One. 2020 Jan 29;15(1):e0228164. doi: 10.1371/journal.pone.0228164. eCollection 2020.


Confidence of recurrent cellulitis self-diagnosis among people with lymphoedema: a qualitative interview study.

Patel M, Lee SI, Levell NJ, Smart P, Kai J, Thomas KS, Leighton P.

Br J Gen Pract. 2020 Jan 30;70(691):e130-e137. doi: 10.3399/bjgp19X707909. Print 2020 Feb.


Characterising burden of treatment in cystic fibrosis to identify priority areas for clinical trials.

Davies G, Rowbotham NJ, Smith S, Elliot ZC, Gathercole K, Rayner O, Leighton PA, Herbert S, Duff AJ, Chandran S, Daniels T, Nash EF, Smyth AR.

J Cyst Fibros. 2019 Nov 15. pii: S1569-1993(19)30961-0. doi: 10.1016/j.jcf.2019.10.025. [Epub ahead of print]


Landscape determinants of density of blacklegged ticks, vectors of Lyme disease, at the northern edge of their distribution in Canada.

Talbot B, Slatculescu A, Thickstun CR, Koffi JK, Leighton PA, McKay R, Kulkarni MA.

Sci Rep. 2019 Nov 13;9(1):16652. doi: 10.1038/s41598-019-50858-x.


What matters to patients? A thematic analysis of patient information and support needs.

Osborn K, Bradley J, Knox E, Leighton P.

Eye (Lond). 2020 Jan;34(1):103-115. doi: 10.1038/s41433-019-0644-3. Epub 2019 Nov 12. Review.


Adapting the James Lind Alliance priority setting process to better support patient participation: an example from cystic fibrosis.

Rowbotham NJ, Smith SJ, Elliott ZC, Leighton PA, Rayner OC, Morley R, Smyth AR.

Res Involv Engagem. 2019 Aug 20;5:24. doi: 10.1186/s40900-019-0159-x. eCollection 2019.


Seeking a practical definition of stable glaucoma: a Delphi consensus survey of UK glaucoma consultants.

Lakhani BK, Giannouladis K, Leighton P, King AJ.

Eye (Lond). 2020 Feb;34(2):335-343. doi: 10.1038/s41433-019-0540-x. Epub 2019 Aug 5.


Treatment interventions for hand fractures and joint injuries: a scoping review of randomized controlled trials.

Mousoulis C, Thomas K, Leighton P, Deshmukh S, Grindlay D, Karantana A.

J Hand Surg Eur Vol. 2020 Feb;45(2):111-118. doi: 10.1177/1753193419865897. Epub 2019 Aug 5.


ASSERT (Acute Sacral inSufficiEncy fractuRe augmenTation) randomised controlled, feasibility in older people trial: a study protocol.

van Berkel D, Ong T, Drummond A, Hendrick P, Leighton P, Jones M, Salem K, Quraishi N, Brookes C, Suazo Di Paola A, Edwards S, Sahota O.

BMJ Open. 2019 Jul 10;9(7):e032111. doi: 10.1136/bmjopen-2019-032111.


N Increased risk of tick-borne diseases with climate and environmental changes.

Bouchard C, Dibernardo A, Koffi J, Wood H, Leighton PA, Lindsay LR.

Can Commun Dis Rep. 2019 Apr 4;45(4):83-89. doi: 10.14745/ccdr.v45i04a02. eCollection 2019 Apr 4.


What is the real number of Lyme disease cases in Canada?

Ogden NH, Bouchard C, Badcock J, Drebot MA, Elias SP, Hatchette TF, Koffi JK, Leighton PA, Lindsay LR, Lubelczyk CB, Peregrine AS, Smith RP, Webster D.

BMC Public Health. 2019 Jun 28;19(1):849. doi: 10.1186/s12889-019-7219-x.


Exploring patients' expectations and preferences of glaucoma surgery outcomes to facilitate healthcare delivery and inform future glaucoma research.

Kulkarni BB, Leighton P, King AJ.

Br J Ophthalmol. 2019 Dec;103(12):1850-1855. doi: 10.1136/bjophthalmol-2018-313401. Epub 2019 Apr 3.


Serological and molecular detection of Toxoplasma gondii in terrestrial and marine wildlife harvested for food in Nunavik, Canada.

Bachand N, Ravel A, Leighton P, Stephen C, Ndao M, Avard E, Jenkins E.

Parasit Vectors. 2019 Apr 3;12(1):155. doi: 10.1186/s13071-019-3408-9.


SKIP (Supporting Kids with diabetes In Physical activity): Feasibility of a randomised controlled trial of a digital intervention for 9-12 year olds with type 1 diabetes mellitus.

Knox E, Glazebrook C, Randell T, Leighton P, Guo B, Greening J, Davies EB, Amor L, Blake H.

BMC Public Health. 2019 Apr 3;19(1):371. doi: 10.1186/s12889-019-6697-1.


A framework for adaptive surveillance of emerging tick-borne zoonoses.

Clow KM, Leighton PA, Pearl DL, Jardine CM.

One Health. 2019 Feb 11;7:100083. doi: 10.1016/j.onehlt.2019.100083. eCollection 2019 Jun. Review.


The use of the Delphi method for hand surgery research.

Johnson N, Leighton P, Dias J.

J Hand Surg Eur Vol. 2019 Jun;44(5):547-550. doi: 10.1177/1753193419829669. Epub 2019 Feb 21. No abstract available.


Detection of municipalities at-risk of Lyme disease using passive surveillance of Ixodes scapularis as an early signal: A province-specific indicator in Canada.

Gasmi S, Ogden NH, Ripoche M, Leighton PA, Lindsay RL, Nelder MP, Rees E, Bouchard C, Vrbova L, Rusk R, Russell C, Pelcat Y, Mechai S, Kotchi SO, Koffi JK.

PLoS One. 2019 Feb 19;14(2):e0212637. doi: 10.1371/journal.pone.0212637. eCollection 2019.


Short-term Forecasting of Daily Abundance of West Nile Virus Vectors Culex pipiens-restuans (Diptera: Culicidae) and Aedes vexans Based on Weather Conditions in Southern Québec (Canada).

Ripoche M, Campagna C, Ludwig A, Ogden NH, Leighton PA.

J Med Entomol. 2019 Apr 16;56(3):859-872. doi: 10.1093/jme/tjz002.


Defining displacement thresholds for surgical intervention for distal radius fractures - A Delphi study.

Johnson N, Leighton P; Distal Radius Fracture Delphi Study Group, Pailthorpe C, Dias J.

PLoS One. 2019 Jan 8;14(1):e0210462. doi: 10.1371/journal.pone.0210462. eCollection 2019.


Understanding the Connections Between Dogs, Health and Inuit Through a Mixed-Methods Study.

Aenishaenslin C, Brunet P, Lévesque F, Gouin GG, Simon A, Saint-Charles J, Leighton P, Bastian S, Ravel A.

Ecohealth. 2019 Mar;16(1):151-160. doi: 10.1007/s10393-018-1386-6. Epub 2018 Dec 14.


Foxes (Vulpes vulpes) as sentinels for parasitic zoonoses, Toxoplasma gondii and Trichinella nativa, in the northeastern Canadian Arctic.

Nicholas B, Ravel A, Leighton P, Stephen C, Iqbal A, Ndao M, Konecsni K, Fernando C, Jenkins E.

Int J Parasitol Parasites Wildl. 2018 Oct 17;7(3):391-397. doi: 10.1016/j.ijppaw.2018.10.003. eCollection 2018 Dec.


Production of Transgenic Chickens Using Cultured Primordial Germ Cells and Gonocytes.

Collarini EJ, Leighton PA, Van de Lavoir MC.

Methods Mol Biol. 2019;1874:403-430. doi: 10.1007/978-1-4939-8831-0_24.


Evidence for increasing densities and geographic ranges of tick species of public health significance other than Ixodes scapularis in Québec, Canada.

Gasmi S, Bouchard C, Ogden NH, Adam-Poupart A, Pelcat Y, Rees EE, Milord F, Leighton PA, Lindsay RL, Koffi JK, Thivierge K.

PLoS One. 2018 Aug 22;13(8):e0201924. doi: 10.1371/journal.pone.0201924. eCollection 2018.


V(D)J Rearrangement Is Dispensable for Producing CDR-H3 Sequence Diversity in a Gene Converting Species.

Leighton PA, Morales J, Harriman WD, Ching KH.

Front Immunol. 2018 Jun 11;9:1317. doi: 10.3389/fimmu.2018.01317. eCollection 2018.


Prion gene paralogs are dispensable for early zebrafish development and have nonadditive roles in seizure susceptibility.

Leighton PLA, Kanyo R, Neil GJ, Pollock NM, Allison WT.

J Biol Chem. 2018 Aug 10;293(32):12576-12592. doi: 10.1074/jbc.RA117.001171. Epub 2018 Jun 14.


Development of a multimedia educational programme for first-time hearing aid users: a participatory design.

Ferguson M, Leighton P, Brandreth M, Wharrad H.

Int J Audiol. 2018 Aug;57(8):600-609. doi: 10.1080/14992027.2018.1457803. Epub 2018 May 2. Review.


Integrated Social-Behavioral and Ecological Risk Maps to Prioritize Local Public Health Responses to Lyme Disease.

Bouchard C, Aenishaenslin C, Rees EE, Koffi JK, Pelcat Y, Ripoche M, Milord F, Lindsay LR, Ogden NH, Leighton PA.

Environ Health Perspect. 2018 Apr 18;126(4):047008. doi: 10.1289/EHP1943.


Chair based exercise in community settings: a cluster randomised feasibility study.

Robinson KR, Long AL, Leighton P, Armstrong S, Pulikottill-Jacob R, Gladman JRF, Gordon AL, Logan P, Anthony KA, Harwood RH, Blackshaw PE, Masud T.

BMC Geriatr. 2018 Apr 3;18(1):82. doi: 10.1186/s12877-018-0769-4.


Multi-Scale Clustering of Lyme Disease Risk at the Expanding Leading Edge of the Range of Ixodes scapularis in Canada.

Ripoche M, Lindsay LR, Ludwig A, Ogden NH, Thivierge K, Leighton PA.

Int J Environ Res Public Health. 2018 Mar 27;15(4). pii: E603. doi: 10.3390/ijerph15040603.


High-Resolution Ecological Niche Modeling of Ixodes scapularis Ticks Based on Passive Surveillance Data at the Northern Frontier of Lyme Disease Emergence in North America.

Soucy JR, Slatculescu AM, Nyiraneza C, Ogden NH, Leighton PA, Kerr JT, Kulkarni MA.

Vector Borne Zoonotic Dis. 2018 May;18(5):235-242. doi: 10.1089/vbz.2017.2234. Epub 2018 Mar 22.


Passive Tick Surveillance Provides an Accurate Early Signal of Emerging Lyme Disease Risk and Human Cases in Southern Canada.

Ripoche M, Gasmi S, Adam-Poupart A, Koffi JK, Lindsay LR, Ludwig A, Milord F, Ogden NH, Thivierge K, Leighton PA.

J Med Entomol. 2018 Jun 28;55(4):1016-1026. doi: 10.1093/jme/tjy030.


Home-based pre-surgical psychological intervention for knee osteoarthritis (HAPPiKNEES): a feasibility randomized controlled trial.

das Nair R, Mhizha-Murira JR, Anderson P, Carpenter H, Clarke S, Groves S, Leighton P, Scammell BE, Topcu G, Walsh DA, Lincoln NB.

Clin Rehabil. 2018 Jun;32(6):777-789. doi: 10.1177/0269215518755426. Epub 2018 Feb 9.


An ancient conserved role for prion protein in learning and memory.

Leighton PLA, Nadolski NJ, Morrill A, Hamilton TJ, Allison WT.

Biol Open. 2018 Jan 22;7(1). pii: bio025734. doi: 10.1242/bio.025734.


Interventions to improve retention in a surgical, clinical trial: A pragmatic, stakeholder-driven approach.

Leighton PA, Brealey SD, Dias JJ.

J Evid Based Med. 2018 Feb;11(1):12-19. doi: 10.1111/jebm.12271. Epub 2018 Jan 22.


Northward range expansion of Ixodes scapularis evident over a short timescale in Ontario, Canada.

Clow KM, Leighton PA, Ogden NH, Lindsay LR, Michel P, Pearl DL, Jardine CM.

PLoS One. 2017 Dec 27;12(12):e0189393. doi: 10.1371/journal.pone.0189393. eCollection 2017.


Reduced Abundance and Subverted Functions of Proteins in Prion-Like Diseases: Gained Functions Fascinate but Lost Functions Affect Aetiology.

Allison WT, DuVal MG, Nguyen-Phuoc K, Leighton PLA.

Int J Mol Sci. 2017 Oct 24;18(10). pii: E2223. doi: 10.3390/ijms18102223. Review.


Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets.

Ching KH, Collarini EJ, Abdiche YN, Bedinger D, Pedersen D, Izquierdo S, Harriman R, Zhu L, Etches RJ, van de Lavoir MC, Harriman WD, Leighton PA.

MAbs. 2018 Jan;10(1):71-80. doi: 10.1080/19420862.2017.1386825. Epub 2017 Nov 2.


The top 10 research priorities in cystic fibrosis developed by a partnership between people with CF and healthcare providers.

Rowbotham NJ, Smith S, Leighton PA, Rayner OC, Gathercole K, Elliott ZC, Nash EF, Daniels T, Duff AJA, Collins S, Chandran S, Peaple U, Hurley MN, Brownlee K, Smyth AR.

Thorax. 2018 Apr;73(4):388-390. doi: 10.1136/thoraxjnl-2017-210473. Epub 2017 Aug 4.


Immediate Impact of Centralization on Abdominal Aortic Aneurysm Repair Outcomes for a Vascular Network in the South West of England: A Retrospective Cohort Study.

Leighton P, Doe M, Pathak S, AlDuwaisan A, Brooks M.

Ann Surg. 2019 Jan;269(1):172-176. doi: 10.1097/SLA.0000000000002330.


Coping together with hearing loss: a qualitative meta-synthesis of the psychosocial experiences of people with hearing loss and their communication partners.

Barker AB, Leighton P, Ferguson MA.

Int J Audiol. 2017 May;56(5):297-305. doi: 10.1080/14992027.2017.1286695. Epub 2017 Feb 24. Review.


Practices of Lyme disease diagnosis and treatment by general practitioners in Quebec, 2008-2015.

Gasmi S, Ogden NH, Leighton PA, Adam-Poupart A, Milord F, Lindsay LR, Barkati S, Thivierge K.

BMC Fam Pract. 2017 May 22;18(1):65. doi: 10.1186/s12875-017-0636-y.


Prioritising topics for the undergraduate ENT curriculum.

Constable JD, Moghul GA, Leighton P, Schofield SJ, Daniel M.

J Laryngol Otol. 2017 Jul;131(7):631-639. doi: 10.1017/S0022215117001025. Epub 2017 May 9.


Perception of first respiratory infection with Pseudomonas aeruginosa by people with cystic fibrosis and those close to them: an online qualitative study.

Palser SC, Rayner OC, Leighton PA, Smyth AR.

BMJ Open. 2016 Dec 28;6(12):e012303. doi: 10.1136/bmjopen-2016-012303.


Analysis of the human population bitten by Ixodes scapularis ticks in Quebec, Canada: Increasing risk of Lyme disease.

Gasmi S, Ogden NH, Leighton PA, Lindsay LR, Thivierge K.

Ticks Tick Borne Dis. 2016 Oct;7(6):1075-1081. doi: 10.1016/j.ttbdis.2016.09.006. Epub 2016 Sep 13.


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