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Items: 1 to 50 of 454

1.

The Clinician's Guide to Suspected Small Bowel Bleeding.

Kuo JR, Pasha SF, Leighton JA.

Am J Gastroenterol. 2018 Dec 20. doi: 10.1038/s41395-018-0424-x. [Epub ahead of print]

PMID:
30747768
2.

Novel Genetic Risk Variants Can Predict Anti-TNF Agent Response in Patients With Inflammatory Bowel Disease.

Wang MH, Friton JJ, Raffals LE, Leighton JA, Pasha SF, Picco MF, Cushing KC, Monroe K, Nix BD, Newberry RD, Faubion WA.

J Crohns Colitis. 2019 Jan 21. doi: 10.1093/ecco-jcc/jjz017. [Epub ahead of print]

PMID:
30689765
3.

Acute Left Internal Carotid Artery and Right Popliteal Artery Occlusion Related to Cisplatin-Gemcitabine Based Chemotherapy.

Zafar S, Potdar R, Tiu A, Varadi G, Leighton J.

Case Rep Neurol Med. 2018 Dec 17;2018:9281918. doi: 10.1155/2018/9281918. eCollection 2018.

4.

Public Health Rising to the Challenge: The Bloomberg American Health Initiative.

Sharfstein JM, Leighton J, Sommer A, MacKenzie EJ.

Public Health Rep. 2018 Nov/Dec;133(1_suppl):3S-4S. doi: 10.1177/0033354918799744. No abstract available.

PMID:
30426869
5.

Design and 22-step synthesis of highly potent D-ring modified and linker-equipped analogs of spongistatin 1.

Suen LM, Tekle-Smith MA, Williamson KS, Infantine JR, Reznik SK, Tanis PS, Casselman TD, Sackett DL, Leighton JL.

Nat Commun. 2018 Nov 9;9(1):4710. doi: 10.1038/s41467-018-07259-x.

6.

Synthetic Graft Compared With Allograft Reconstruction for Extensor Mechanism Disruption in Total Knee Arthroplasty: A Multicenter Cohort Study.

Wood TJ, Leighton J, Backstein DJ, Marsh JD, Howard JL, McCalden RW, MacDonald SJ, Lanting BA.

J Am Acad Orthop Surg. 2018 Oct 30. doi: 10.5435/JAAOS-D-18-00393. [Epub ahead of print]

PMID:
30379759
7.

Hip and Knee Section, Treatment, Surgical Technique: Proceedings of International Consensus on Orthopedic Infections.

Abouljoud MM, Backstein D, Battenberg A, Dietz M, Erice A, Freiberg AA, Granger J, Katchky A, Khlopas A, Kim TK, Kjaersgaard-Andersen P, Koo KH, Kosashvili Y, Lazarovski P, Leighton J, Lombardi A, Malizos K, Manrique J, Mont MA, Papanagiotoy M, Sierra RJ, Sodhi N, Stammers J, Stiehler M, Tan TL, Uchiyama K, Ward D, Ziogkou A.

J Arthroplasty. 2019 Feb;34(2S):S445-S451. doi: 10.1016/j.arth.2018.09.029. Epub 2018 Oct 19. No abstract available.

PMID:
30348548
8.

Symptoms of PBC - Pathophysiology and management.

Khanna A, Leighton J, Lee Wong L, Jones DE.

Best Pract Res Clin Gastroenterol. 2018 Jun - Aug;34-35:41-47. doi: 10.1016/j.bpg.2018.06.007. Epub 2018 Jun 14. Review.

PMID:
30343709
9.

Family History Associates With Increased Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases.

Samadder NJ, Valentine JF, Guthery S, Singh H, Bernstein CN, Leighton JA, Wan Y, Wong J, Boucher K, Pappas L, Rowe K, Burt RW, Curtin K, Smith KR.

Clin Gastroenterol Hepatol. 2018 Sep 26. pii: S1542-3565(18)31029-2. doi: 10.1016/j.cgh.2018.09.038. [Epub ahead of print]

PMID:
30267862
10.

Utility of video capsule endoscopy for longitudinal monitoring of Crohn's disease activity in the small bowel: a prospective study.

Melmed GY, Dubinsky MC, Rubin DT, Fleisher M, Pasha SF, Sakuraba A, Tiongco F, Shafran I, Fernandez-Urien I, Rosa B, Papageorgiou NP, Leighton JA.

Gastrointest Endosc. 2018 Dec;88(6):947-955.e2. doi: 10.1016/j.gie.2018.07.035. Epub 2018 Aug 4.

PMID:
30086261
11.

Genomic medicine: it is time to act.

Leighton J, Stacey J, Brennan P.

Br J Hosp Med (Lond). 2018 Aug 2;79(8):426. doi: 10.12968/hmed.2018.79.8.426. No abstract available.

PMID:
30070950
12.

Trends and Outcomes of Venous Thromboembolism in Hospitalized Patients With Ovarian Cancer: Results From Nationwide Inpatient Sample Database 2003 to 2011.

Mittal V, Ahuja S, Vejella SS, Stempel JM, Palabindala V, Dourado CM, Leighton JC.

Int J Gynecol Cancer. 2018 Oct;28(8):1478-1484. doi: 10.1097/IGC.0000000000001335.

PMID:
30045139
13.

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types.

Ge Z, Leighton JS, Wang Y, Peng X, Chen Z, Chen H, Sun Y, Yao F, Li J, Zhang H, Liu J, Shriver CD, Hu H; Cancer Genome Atlas Research Network, Piwnica-Worms H, Ma L, Liang H.

Cell Rep. 2018 Apr 3;23(1):213-226.e3. doi: 10.1016/j.celrep.2018.03.047.

14.

Is the level of cleanliness using segmental Boston bowel preparation scale associated with a higher adenoma detection rate?

Adike A, Buras MR, Gurudu SR, Leighton JA, Faigel DO, Ruff KC, Umar SB, Ramirez FC.

Ann Gastroenterol. 2018 Mar-Apr;31(2):217-223. doi: 10.20524/aog.2018.0231. Epub 2018 Jan 31.

15.

SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.

Qin K, Zhang N, Zhang Z, Nipper M, Zhu Z, Leighton J, Xu K, Musi N, Wang P.

Diabetologia. 2018 Apr;61(4):906-918. doi: 10.1007/s00125-017-4542-6. Epub 2018 Jan 10.

PMID:
29322219
16.

Direct, Mild, and General n-Bu4NBr-Catalyzed Aldehyde Allylsilylation with Allyl Chlorides.

Tekle-Smith MA, Williamson KS, Hughes IF, Leighton JL.

Org Lett. 2017 Nov 3;19(21):6024-6027. doi: 10.1021/acs.orglett.7b03193.

17.

Impact of feedback on adenoma detection rates: Outcomes of quality improvement program.

Gurudu SR, Boroff ES, Crowell MD, Atia M, Umar SB, Leighton JA, Faigel DO, Ramirez FC.

J Gastroenterol Hepatol. 2018 Mar;33(3):645-649. doi: 10.1111/jgh.13984.

PMID:
28892839
18.

An FDA oncology analysis of CD3 bispecific constructs and first-in-human dose selection.

Saber H, Del Valle P, Ricks TK, Leighton JK.

Regul Toxicol Pharmacol. 2017 Nov;90:144-152. doi: 10.1016/j.yrtph.2017.09.001. Epub 2017 Sep 5. Review.

PMID:
28887049
19.

Approach to Incomplete Colonoscopy: New Techniques and Technologies.

Franco DL, Leighton JA, Gurudu SR.

Gastroenterol Hepatol (N Y). 2017 Aug;13(8):476-483.

20.

Synthesis and Evaluation of a Linkable Functional Group-Equipped Analogue of the Epothilones.

Foley CN, Chen LA, Sackett DL, Leighton JL.

ACS Med Chem Lett. 2017 May 1;8(7):701-704. doi: 10.1021/acsmedchemlett.7b00131. eCollection 2017 Jul 13.

21.

The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer.

Uribe DJ, Mandell EK, Watson A, Martinez JD, Leighton JA, Ghosh S, Rothlin CV.

PLoS One. 2017 Jul 20;12(7):e0179979. doi: 10.1371/journal.pone.0179979. eCollection 2017.

22.

Duodenal gangliocytic paraganglioma: Endoscopy, sonography and F-18 FDG PET/CT imaging.

Yang M, Leighton JA, Faigel DO, Katariya NN.

Dig Liver Dis. 2017 Oct;49(10):1162. doi: 10.1016/j.dld.2017.05.006. Epub 2017 May 18. No abstract available.

PMID:
28579473
23.

Evidence-Based Guide on Capsule Endoscopy for Small Bowel Bleeding.

Pasha SF, Leighton JA.

Gastroenterol Hepatol (N Y). 2017 Feb;13(2):88-93.

24.

Silane and Germane Molecular Electronics.

Su TA, Li H, Klausen RS, Kim NT, Neupane M, Leighton JL, Steigerwald ML, Venkataraman L, Nuckolls C.

Acc Chem Res. 2017 Apr 18;50(4):1088-1095. doi: 10.1021/acs.accounts.7b00059. Epub 2017 Mar 27.

PMID:
28345881
25.

Evolution of an Efficient and Scalable Nine-Step (Longest Linear Sequence) Synthesis of Zincophorin Methyl Ester.

Chen LA, Ashley MA, Leighton JL.

J Am Chem Soc. 2017 Mar 29;139(12):4568-4573. doi: 10.1021/jacs.7b01590. Epub 2017 Mar 15.

26.

Identification of Antibody Against SNRPB, Small Nuclear Ribonucleoprotein-Associated Proteins B and B', as an Autoantibody Marker in Crohn's Disease using an Immunoproteomics Approach.

Wang H, Demirkan G, Bian X, Wallstrom G, Barker K, Karthikeyan K, Tang Y, Pasha SF, Leighton JA, Qiu J, LaBaer J.

J Crohns Colitis. 2017 Jul 1;11(7):848-856. doi: 10.1093/ecco-jcc/jjx019.

PMID:
28204086
27.

Generation of endoderm lineages from pluripotent stem cells.

Luo X, Wang H, Leighton J, O'Sullivan M, Wang P.

Regen Med. 2017 Jan;12(1):77-89. doi: 10.2217/rme-2016-0086. Epub 2016 Dec 15. Review.

PMID:
27976977
28.

Mechanism for Si-Si Bond Rupture in Single Molecule Junctions.

Li H, Kim NT, Su TA, Steigerwald ML, Nuckolls C, Darancet P, Leighton JL, Venkataraman L.

J Am Chem Soc. 2016 Dec 14;138(49):16159-16164. Epub 2016 Nov 30.

PMID:
27960303
29.

Inflammatory Disorders of the Small Bowel.

Leighton JA, Pasha SF.

Gastrointest Endosc Clin N Am. 2017 Jan;27(1):63-77. doi: 10.1016/j.giec.2016.08.004.

PMID:
27908519
30.

An FDA oncology analysis of immune activating products and first-in-human dose selection.

Saber H, Gudi R, Manning M, Wearne E, Leighton JK.

Regul Toxicol Pharmacol. 2016 Nov;81:448-456. doi: 10.1016/j.yrtph.2016.10.002. Epub 2016 Oct 13.

PMID:
27743776
31.

Comparing diagnostic yield of a novel pan-enteric video capsule endoscope with ileocolonoscopy in patients with active Crohn's disease: a feasibility study.

Leighton JA, Helper DJ, Gralnek IM, Dotan I, Fernandez-Urien I, Lahat A, Malik P, Mullin GE, Rosa B.

Gastrointest Endosc. 2017 Jan;85(1):196-205.e1. doi: 10.1016/j.gie.2016.09.009. Epub 2016 Sep 19.

PMID:
27658907
32.

Detection of suspected small bowel bleeding: challenges and controversies.

Pasha SF, Leighton JA.

Expert Rev Gastroenterol Hepatol. 2016 Nov;10(11):1235-1244. Epub 2016 Jul 7. Review.

PMID:
27366927
33.

Accuracy of First- and Second-Generation Colon Capsules in Endoscopic Detection of Colorectal Polyps: A Systematic Review and Meta-analysis.

Spada C, Pasha SF, Gross SA, Leighton JA, Schnoll-Sussman F, Correale L, González Suárez B, Costamagna G, Hassan C.

Clin Gastroenterol Hepatol. 2016 Nov;14(11):1533-1543.e8. doi: 10.1016/j.cgh.2016.04.038. Epub 2016 May 7. Review.

34.

High-Conductance Pathways in Ring-Strained Disilanes by Way of Direct σ-Si-Si to Au Coordination.

Kim NT, Li H, Venkataraman L, Leighton JL.

J Am Chem Soc. 2016 Sep 14;138(36):11505-8. doi: 10.1021/jacs.6b07825. Epub 2016 Sep 2.

PMID:
27563932
35.
36.

Characterization of a Saccharomyces cerevisiae fermentation process for production of a therapeutic recombinant protein using a multivariate Bayesian approach.

Fu Z, Baker D, Cheng A, Leighton J, Appelbaum E, Aon J.

Biotechnol Prog. 2016 May;32(3):799-812. doi: 10.1002/btpr.2264. Epub 2016 Apr 20.

PMID:
27095416
37.

An FDA oncology view of juvenile animal studies in support of initial pediatric trials for anticancer drugs.

Leighton JK, Saber H, Reaman G, Pazdur R.

Regul Toxicol Pharmacol. 2016 Aug;79:142-143. doi: 10.1016/j.yrtph.2016.03.001. Epub 2016 Mar 4. No abstract available.

PMID:
26952647
38.

Response to Perez-Cuadrado Robles.

Gerson LB, Fidler JL, Cave DR, Leighton JA.

Am J Gastroenterol. 2016 Feb;111(2):294-5. doi: 10.1038/ajg.2015.428. No abstract available.

PMID:
26882946
39.

The Elusive Bleeder: Tips for Avoiding a Wild Goose Chase.

Pasha SF, Leighton JA.

Am J Gastroenterol. 2016 Mar;111(3):301-4. doi: 10.1038/ajg.2016.11. Epub 2016 Feb 9. No abstract available.

PMID:
26856751
40.

A Highly Stereoselective, Efficient, and Scalable Synthesis of the C(1)-C(9) Fragment of the Epothilones.

Foley CN, Leighton JL.

Org Lett. 2015 Dec 4;17(23):5858-61. doi: 10.1021/acs.orglett.5b03034. Epub 2015 Nov 12.

41.

Using Hybrid Change Strategies to Improve the Patient Experience in Outpatient Specialty Care.

Miranda R, Glenn SW, Leighton JA, Pasha SE, Gurudu SR, Teaford HG, Mertz LE, Lee HR, Mamby SA, Johnson MF, Raghu TS.

J Healthc Manag. 2015 Sep-Oct;60(5):363-76.

PMID:
26554148
42.

A "methyl extension" strategy for polyketide natural product linker site validation and its application to dictyostatin.

Ho S, Sackett DL, Leighton JL.

J Am Chem Soc. 2015 Nov 11;137(44):14047-50. doi: 10.1021/jacs.5b09869. Epub 2015 Nov 3.

43.

Extracellular Matrix and Integrins in Embryonic Stem Cell Differentiation.

Wang H, Luo X, Leighton J.

Biochem Insights. 2015 Sep 28;8(Suppl 2):15-21. doi: 10.4137/BCI.S30377. eCollection 2015. Review.

44.

Correction to "Design, Development, Mechanistic Elucidation, and Rational Optimization of a Tandem Ireland Claisen/Cope Rearrangement Reaction for Rapid Access to the (Iso)Cyclocitrinol Core".

Plummer CW, Wei CS, Yozwiak CE, Soheili A, Smithback SO, Leighton JL.

J Am Chem Soc. 2015 Oct 28;137(42):13722. doi: 10.1021/jacs.5b09617. Epub 2015 Oct 13. No abstract available.

PMID:
26461137
45.

Alternatives to Incomplete Colonoscopy.

Villa NA, Pannala R, Pasha SF, Leighton JA.

Curr Gastroenterol Rep. 2015 Nov;17(11):43. doi: 10.1007/s11894-015-0468-7. Review.

PMID:
26374654
46.

ACG Clinical Guideline: Diagnosis and Management of Small Bowel Bleeding.

Gerson LB, Fidler JL, Cave DR, Leighton JA.

Am J Gastroenterol. 2015 Sep;110(9):1265-87; quiz 1288. doi: 10.1038/ajg.2015.246. Epub 2015 Aug 25.

PMID:
26303132
47.

Primary Ureteral Lymphoma Presenting with Acute Flank Pain.

Foote C, Henderson S, Reddy S, Horrow M, Leighton J, Cahn D, Diorio G, Bickell M, Ginsberg P, Metro M.

Curr Urol. 2014 Oct;7(4):210-3. doi: 10.1159/000365679. Epub 2014 Aug 20.

48.

Direct access GP referral for ETT functions as a virtual clinic.

Greaves JH, Leighton JD, Lainchbury JG, Bridgman PG.

N Z Med J. 2015 Jun 12;128(1416):79-80. No abstract available.

PMID:
26117681
49.

Nonneoplastic polypectomy during screening colonoscopy: the impact on polyp detection rate, adenoma detection rate, and overall cost.

Atia MA, Patel NC, Ratuapli SK, Boroff ES, Crowell MD, Gurudu SR, Faigel DO, Leighton JA, Ramirez FC.

Gastrointest Endosc. 2015 Aug;82(2):370-375.e1. doi: 10.1016/j.gie.2015.01.016. Epub 2015 Apr 3.

PMID:
25843614
50.

Double-balloon enteroscopy in Crohn's disease: findings and impact on management in a multicenter retrospective study.

Rahman A, Ross A, Leighton JA, Schembre D, Gerson L, Lo SK, Waxman I, Dye C, Semrad C.

Gastrointest Endosc. 2015 Jul;82(1):102-7. doi: 10.1016/j.gie.2014.12.039. Epub 2015 Apr 1.

PMID:
25840927

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