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Items: 1 to 50 of 462

1.

Prospective Multicenter Study to Evaluate Capsule Endoscopy Competency using a Validated Assessment Tool.

Rajan E, Martinez M, Gorospe E, Al Bawardy B, Dobashi A, Mara KC, Hansel SL, Bruining DH, Murray JA, Leggett CL, Nehra V, Iyer PG, Pasha SF, Leighton JA, Shiff AD, Gurudu SR, Raffals LE, Lavey C, Katzka DA, Chen CH.

Gastrointest Endosc. 2019 Dec 26. pii: S0016-5107(19)32566-0. doi: 10.1016/j.gie.2019.12.024. [Epub ahead of print]

PMID:
31883863
2.

An FDA analysis of clinical hold deficiencies affecting investigational new drug applications for oncology products.

Manning ML, Thompson MD, Saber H, Maher VE, Crich JZ, Leighton JK.

Regul Toxicol Pharmacol. 2020 Feb;110:104511. doi: 10.1016/j.yrtph.2019.104511. Epub 2019 Oct 31.

PMID:
31678263
3.

Unique Phenotypic Characteristics and Clinical Course in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis: A Multicenter US Experience.

Wang MH, Mousa OY, Friton JJ, Raffals LE, Leighton JA, Pasha SF, Picco MF, Cushing KC, Monroe K, Nix BD, Newberry RD, Faubion WA.

Inflamm Bowel Dis. 2019 Oct 18. pii: izz209. doi: 10.1093/ibd/izz209. [Epub ahead of print]

PMID:
31626701
4.

An FDA oncology analysis of toxicities associated with PBD-containing antibody-drug conjugates.

Saber H, Simpson N, Ricks TK, Leighton JK.

Regul Toxicol Pharmacol. 2019 Oct;107:104429. doi: 10.1016/j.yrtph.2019.104429. Epub 2019 Jul 17.

PMID:
31325532
5.

School education to increase organ donation and awareness of issues in transplantation in the UK.

Byrne M, Stainer B, Symington M, Leighton J, Jackson H, Singhal N, Patel S, Shiel-Rankin S, Mayes J, Mogg J, Bonham T, Smit A, Deutsch E, Thompson E, Wilson C.

Pediatr Transplant. 2019 Aug;23(5):e13492. doi: 10.1111/petr.13492. Epub 2019 Jun 3.

PMID:
31157497
6.

Capsule Retention in Crohn's Disease: A Meta-analysis.

Pasha SF, Pennazio M, Rondonotti E, Wolf D, Buras MR, Albert JG, Cohen SA, Cotter J, D'Haens G, Eliakim R, Rubin DT, Leighton JA.

Inflamm Bowel Dis. 2020 Jan 1;26(1):33-42. doi: 10.1093/ibd/izz083.

PMID:
31050736
7.

Erratum to 'Hip and Knee Section, Treatment, Surgical Technique: Proceedings of International Consensus on Orthopedic Infections' [The Journal of Arthroplasty 34 (2019) S445-S451].

Abouljoud MM, Backstein D, Battenberg A, Dietz M, Erice A, Freiberg AA, Granger J, Katchky A, Khlopas A, Kim TK, Kjaersgaard-Andersen P, Koo KH, Kosashvili Y, Lazarovski P, Leighton J, Lombardi A, Malizos K, Manrique J, Mont MA, Papanagiotoy M, Sierra RJ, Sodhi N, Stammers J, Stiehler M, Tan TL, Uchiyama K, Ward D, Ziogkou A.

J Arthroplasty. 2019 Jun;34(6):1300. doi: 10.1016/j.arth.2019.02.063. Epub 2019 Mar 28. No abstract available.

8.

The risk-return trade-off: Performance assessments and cognitive validation of inferences.

Leighton JP.

Br J Educ Psychol. 2019 Sep;89(3):441-455. doi: 10.1111/bjep.12271. Epub 2019 Mar 18.

PMID:
30883702
9.

The Clinician's Guide to Suspected Small Bowel Bleeding.

Kuo JR, Pasha SF, Leighton JA.

Am J Gastroenterol. 2019 Apr;114(4):591-598. doi: 10.1038/s41395-018-0424-x. Review.

PMID:
30747768
10.

Novel Genetic Risk Variants Can Predict Anti-TNF Agent Response in Patients With Inflammatory Bowel Disease.

Wang MH, Friton JJ, Raffals LE, Leighton JA, Pasha SF, Picco MF, Cushing KC, Monroe K, Nix BD, Newberry RD, Faubion WA.

J Crohns Colitis. 2019 Aug 14;13(8):1036-1043. doi: 10.1093/ecco-jcc/jjz017.

PMID:
30689765
11.

Acute Left Internal Carotid Artery and Right Popliteal Artery Occlusion Related to Cisplatin-Gemcitabine Based Chemotherapy.

Zafar S, Potdar R, Tiu A, Varadi G, Leighton J.

Case Rep Neurol Med. 2018 Dec 17;2018:9281918. doi: 10.1155/2018/9281918. eCollection 2018.

12.

Public Health Rising to the Challenge: The Bloomberg American Health Initiative.

Sharfstein JM, Leighton J, Sommer A, MacKenzie EJ.

Public Health Rep. 2018 Nov/Dec;133(1_suppl):3S-4S. doi: 10.1177/0033354918799744. No abstract available.

13.

Design and 22-step synthesis of highly potent D-ring modified and linker-equipped analogs of spongistatin 1.

Suen LM, Tekle-Smith MA, Williamson KS, Infantine JR, Reznik SK, Tanis PS, Casselman TD, Sackett DL, Leighton JL.

Nat Commun. 2018 Nov 9;9(1):4710. doi: 10.1038/s41467-018-07259-x.

14.

Synthetic Graft Compared With Allograft Reconstruction for Extensor Mechanism Disruption in Total Knee Arthroplasty: A Multicenter Cohort Study.

Wood TJ, Leighton J, Backstein DJ, Marsh JD, Howard JL, McCalden RW, MacDonald SJ, Lanting BA.

J Am Acad Orthop Surg. 2019 Jun 15;27(12):451-457. doi: 10.5435/JAAOS-D-18-00393.

PMID:
30379759
15.

Hip and Knee Section, Treatment, Surgical Technique: Proceedings of International Consensus on Orthopedic Infections.

Abouljoud MM, Backstein D, Battenberg A, Dietz M, Erice A, Freiberg AA, Granger J, Katchky A, Khlopas A, Kim TK, Kjaersgaard-Andersen P, Koo KH, Kosashvili Y, Lazarovski P, Leighton J, Lombardi A, Malizos K, Manrique J, Mont MA, Papanagiotoy M, Sierra RJ, Sodhi N, Stammers J, Stiehler M, Tan TL, Uchiyama K, Ward D, Ziogkou A.

J Arthroplasty. 2019 Feb;34(2S):S445-S451. doi: 10.1016/j.arth.2018.09.029. Epub 2018 Oct 19. No abstract available. Erratum in: J Arthroplasty. 2019 Jun;34(6):1300.

16.

Symptoms of PBC - Pathophysiology and management.

Khanna A, Leighton J, Lee Wong L, Jones DE.

Best Pract Res Clin Gastroenterol. 2018 Jun - Aug;34-35:41-47. doi: 10.1016/j.bpg.2018.06.007. Epub 2018 Jun 14. Review.

PMID:
30343709
17.

Family History Associates With Increased Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases.

Samadder NJ, Valentine JF, Guthery S, Singh H, Bernstein CN, Leighton JA, Wan Y, Wong J, Boucher K, Pappas L, Rowe K, Burt RW, Curtin K, Smith KR.

Clin Gastroenterol Hepatol. 2019 Aug;17(9):1807-1813.e1. doi: 10.1016/j.cgh.2018.09.038. Epub 2018 Sep 26.

PMID:
30267862
18.

Utility of video capsule endoscopy for longitudinal monitoring of Crohn's disease activity in the small bowel: a prospective study.

Melmed GY, Dubinsky MC, Rubin DT, Fleisher M, Pasha SF, Sakuraba A, Tiongco F, Shafran I, Fernandez-Urien I, Rosa B, Papageorgiou NP, Leighton JA.

Gastrointest Endosc. 2018 Dec;88(6):947-955.e2. doi: 10.1016/j.gie.2018.07.035. Epub 2018 Aug 4.

PMID:
30086261
19.

Genomic medicine: it is time to act.

Leighton J, Stacey J, Brennan P.

Br J Hosp Med (Lond). 2018 Aug 2;79(8):426. doi: 10.12968/hmed.2018.79.8.426. No abstract available.

PMID:
30070950
20.

Trends and Outcomes of Venous Thromboembolism in Hospitalized Patients With Ovarian Cancer: Results From Nationwide Inpatient Sample Database 2003 to 2011.

Mittal V, Ahuja S, Vejella SS, Stempel JM, Palabindala V, Dourado CM, Leighton JC.

Int J Gynecol Cancer. 2018 Oct;28(8):1478-1484. doi: 10.1097/IGC.0000000000001335.

PMID:
30045139
21.

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types.

Ge Z, Leighton JS, Wang Y, Peng X, Chen Z, Chen H, Sun Y, Yao F, Li J, Zhang H, Liu J, Shriver CD, Hu H; Cancer Genome Atlas Research Network, Piwnica-Worms H, Ma L, Liang H.

Cell Rep. 2018 Apr 3;23(1):213-226.e3. doi: 10.1016/j.celrep.2018.03.047.

22.

Is the level of cleanliness using segmental Boston bowel preparation scale associated with a higher adenoma detection rate?

Adike A, Buras MR, Gurudu SR, Leighton JA, Faigel DO, Ruff KC, Umar SB, Ramirez FC.

Ann Gastroenterol. 2018 Mar-Apr;31(2):217-223. doi: 10.20524/aog.2018.0231. Epub 2018 Jan 31.

23.

SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.

Qin K, Zhang N, Zhang Z, Nipper M, Zhu Z, Leighton J, Xu K, Musi N, Wang P.

Diabetologia. 2018 Apr;61(4):906-918. doi: 10.1007/s00125-017-4542-6. Epub 2018 Jan 10.

24.

Direct, Mild, and General n-Bu4NBr-Catalyzed Aldehyde Allylsilylation with Allyl Chlorides.

Tekle-Smith MA, Williamson KS, Hughes IF, Leighton JL.

Org Lett. 2017 Nov 3;19(21):6024-6027. doi: 10.1021/acs.orglett.7b03193.

25.

Impact of feedback on adenoma detection rates: Outcomes of quality improvement program.

Gurudu SR, Boroff ES, Crowell MD, Atia M, Umar SB, Leighton JA, Faigel DO, Ramirez FC.

J Gastroenterol Hepatol. 2018 Mar;33(3):645-649. doi: 10.1111/jgh.13984.

PMID:
28892839
26.

An FDA oncology analysis of CD3 bispecific constructs and first-in-human dose selection.

Saber H, Del Valle P, Ricks TK, Leighton JK.

Regul Toxicol Pharmacol. 2017 Nov;90:144-152. doi: 10.1016/j.yrtph.2017.09.001. Epub 2017 Sep 5. Review.

PMID:
28887049
27.

Approach to Incomplete Colonoscopy: New Techniques and Technologies.

Franco DL, Leighton JA, Gurudu SR.

Gastroenterol Hepatol (N Y). 2017 Aug;13(8):476-483.

28.

Synthesis and Evaluation of a Linkable Functional Group-Equipped Analogue of the Epothilones.

Foley CN, Chen LA, Sackett DL, Leighton JL.

ACS Med Chem Lett. 2017 May 1;8(7):701-704. doi: 10.1021/acsmedchemlett.7b00131. eCollection 2017 Jul 13.

29.

The receptor tyrosine kinase AXL promotes migration and invasion in colorectal cancer.

Uribe DJ, Mandell EK, Watson A, Martinez JD, Leighton JA, Ghosh S, Rothlin CV.

PLoS One. 2017 Jul 20;12(7):e0179979. doi: 10.1371/journal.pone.0179979. eCollection 2017.

30.

Duodenal gangliocytic paraganglioma: Endoscopy, sonography and F-18 FDG PET/CT imaging.

Yang M, Leighton JA, Faigel DO, Katariya NN.

Dig Liver Dis. 2017 Oct;49(10):1162. doi: 10.1016/j.dld.2017.05.006. Epub 2017 May 18. No abstract available.

PMID:
28579473
31.

Evidence-Based Guide on Capsule Endoscopy for Small Bowel Bleeding.

Pasha SF, Leighton JA.

Gastroenterol Hepatol (N Y). 2017 Feb;13(2):88-93.

32.

Silane and Germane Molecular Electronics.

Su TA, Li H, Klausen RS, Kim NT, Neupane M, Leighton JL, Steigerwald ML, Venkataraman L, Nuckolls C.

Acc Chem Res. 2017 Apr 18;50(4):1088-1095. doi: 10.1021/acs.accounts.7b00059. Epub 2017 Mar 27.

PMID:
28345881
33.

Evolution of an Efficient and Scalable Nine-Step (Longest Linear Sequence) Synthesis of Zincophorin Methyl Ester.

Chen LA, Ashley MA, Leighton JL.

J Am Chem Soc. 2017 Mar 29;139(12):4568-4573. doi: 10.1021/jacs.7b01590. Epub 2017 Mar 15.

34.

Identification of Antibody Against SNRPB, Small Nuclear Ribonucleoprotein-Associated Proteins B and B', as an Autoantibody Marker in Crohn's Disease using an Immunoproteomics Approach.

Wang H, Demirkan G, Bian X, Wallstrom G, Barker K, Karthikeyan K, Tang Y, Pasha SF, Leighton JA, Qiu J, LaBaer J.

J Crohns Colitis. 2017 Jul 1;11(7):848-856. doi: 10.1093/ecco-jcc/jjx019.

PMID:
28204086
35.

Generation of endoderm lineages from pluripotent stem cells.

Luo X, Wang H, Leighton J, O'Sullivan M, Wang P.

Regen Med. 2017 Jan;12(1):77-89. doi: 10.2217/rme-2016-0086. Epub 2016 Dec 15. Review.

PMID:
27976977
36.

Mechanism for Si-Si Bond Rupture in Single Molecule Junctions.

Li H, Kim NT, Su TA, Steigerwald ML, Nuckolls C, Darancet P, Leighton JL, Venkataraman L.

J Am Chem Soc. 2016 Dec 14;138(49):16159-16164. Epub 2016 Nov 30.

PMID:
27960303
37.

Inflammatory Disorders of the Small Bowel.

Leighton JA, Pasha SF.

Gastrointest Endosc Clin N Am. 2017 Jan;27(1):63-77. doi: 10.1016/j.giec.2016.08.004.

PMID:
27908519
38.

An FDA oncology analysis of immune activating products and first-in-human dose selection.

Saber H, Gudi R, Manning M, Wearne E, Leighton JK.

Regul Toxicol Pharmacol. 2016 Nov;81:448-456. doi: 10.1016/j.yrtph.2016.10.002. Epub 2016 Oct 13.

PMID:
27743776
39.

Comparing diagnostic yield of a novel pan-enteric video capsule endoscope with ileocolonoscopy in patients with active Crohn's disease: a feasibility study.

Leighton JA, Helper DJ, Gralnek IM, Dotan I, Fernandez-Urien I, Lahat A, Malik P, Mullin GE, Rosa B.

Gastrointest Endosc. 2017 Jan;85(1):196-205.e1. doi: 10.1016/j.gie.2016.09.009. Epub 2016 Sep 19.

PMID:
27658907
40.

Detection of suspected small bowel bleeding: challenges and controversies.

Pasha SF, Leighton JA.

Expert Rev Gastroenterol Hepatol. 2016 Nov;10(11):1235-1244. Epub 2016 Jul 7. Review.

PMID:
27366927
41.

Accuracy of First- and Second-Generation Colon Capsules in Endoscopic Detection of Colorectal Polyps: A Systematic Review and Meta-analysis.

Spada C, Pasha SF, Gross SA, Leighton JA, Schnoll-Sussman F, Correale L, González Suárez B, Costamagna G, Hassan C.

Clin Gastroenterol Hepatol. 2016 Nov;14(11):1533-1543.e8. doi: 10.1016/j.cgh.2016.04.038. Epub 2016 May 7. Review.

42.

High-Conductance Pathways in Ring-Strained Disilanes by Way of Direct σ-Si-Si to Au Coordination.

Kim NT, Li H, Venkataraman L, Leighton JL.

J Am Chem Soc. 2016 Sep 14;138(36):11505-8. doi: 10.1021/jacs.6b07825. Epub 2016 Sep 2.

PMID:
27563932
43.
44.

Characterization of a Saccharomyces cerevisiae fermentation process for production of a therapeutic recombinant protein using a multivariate Bayesian approach.

Fu Z, Baker D, Cheng A, Leighton J, Appelbaum E, Aon J.

Biotechnol Prog. 2016 May;32(3):799-812. doi: 10.1002/btpr.2264. Epub 2016 Apr 20.

PMID:
27095416
45.

An FDA oncology view of juvenile animal studies in support of initial pediatric trials for anticancer drugs.

Leighton JK, Saber H, Reaman G, Pazdur R.

Regul Toxicol Pharmacol. 2016 Aug;79:142-143. doi: 10.1016/j.yrtph.2016.03.001. Epub 2016 Mar 4. No abstract available.

PMID:
26952647
46.

Response to Perez-Cuadrado Robles.

Gerson LB, Fidler JL, Cave DR, Leighton JA.

Am J Gastroenterol. 2016 Feb;111(2):294-5. doi: 10.1038/ajg.2015.428. No abstract available.

PMID:
26882946
47.

The Elusive Bleeder: Tips for Avoiding a Wild Goose Chase.

Pasha SF, Leighton JA.

Am J Gastroenterol. 2016 Mar;111(3):301-4. doi: 10.1038/ajg.2016.11. Epub 2016 Feb 9. No abstract available.

PMID:
26856751
48.

A Highly Stereoselective, Efficient, and Scalable Synthesis of the C(1)-C(9) Fragment of the Epothilones.

Foley CN, Leighton JL.

Org Lett. 2015 Dec 4;17(23):5858-61. doi: 10.1021/acs.orglett.5b03034. Epub 2015 Nov 12.

49.

Using Hybrid Change Strategies to Improve the Patient Experience in Outpatient Specialty Care.

Miranda R, Glenn SW, Leighton JA, Pasha SE, Gurudu SR, Teaford HG, Mertz LE, Lee HR, Mamby SA, Johnson MF, Raghu TS.

J Healthc Manag. 2015 Sep-Oct;60(5):363-76.

PMID:
26554148
50.

A "methyl extension" strategy for polyketide natural product linker site validation and its application to dictyostatin.

Ho S, Sackett DL, Leighton JL.

J Am Chem Soc. 2015 Nov 11;137(44):14047-50. doi: 10.1021/jacs.5b09869. Epub 2015 Nov 3.

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