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Whole Genome Sequencing of Spontaneously Occurring Rat Natural Killer Large Granular Lymphocyte Leukemia Identifies JAK1 Somatic Activating Mutation.

Wang TT, Yang J, Dighe S, Schmachtenberg MW, Leigh NT, Farber E, Onengut-Gumuscu S, Feith DJ, Ratan A, Loughran TP Jr, Olson TL.

Cancers (Basel). 2020 Jan 3;12(1). pii: E126. doi: 10.3390/cancers12010126.


The Safety of Iterative Cytoreductive Surgery and HIPEC for Peritoneal Carcinomatosis: A High Volume Center Prospectively Maintained Database Analysis.

Bekhor E, Carr J, Hofstedt M, Sullivan B, Solomon D, Leigh N, Bolton N, Golas B, Sarpel U, Labow D, Magge D.

Ann Surg Oncol. 2019 Dec 23. doi: 10.1245/s10434-019-08141-w. [Epub ahead of print]


A statistical solution to the chaotic, non-hierarchical three-body problem.

Stone NC, Leigh NWC.

Nature. 2019 Dec;576(7787):406-410. doi: 10.1038/s41586-019-1833-8. Epub 2019 Dec 18.


Discovery and Characterization of Halogenated Xanthene Inhibitors of DUSP5 as Potential Photodynamic Therapeutics.

Bongard RD, Lepley M, Gastonguay A, Syrlybaeva RR, Talipov MR, Lipinsky RAJ, Leigh NR, Brahmbhatt J, Kutty R, Rathore R, Ramchandran R, Sem DS.

J Photochem Photobiol A Chem. 2019 Apr 15;375:114-131. doi: 10.1016/j.jphotochem.2019.01.005. Epub 2019 Feb 10.


Splenic flexure mobilization for sigmoid and low anterior resections in the minimally invasive era: How often and at what cost?

Pettke E, Leigh N, Shah A, Cekic V, Yan X, Kumara HMCS, Gandhi N, Whelan RL.

Am J Surg. 2019 Sep 26. pii: S0002-9610(19)30101-1. doi: 10.1016/j.amjsurg.2019.09.029. [Epub ahead of print]


In Vitro Consequences of Electronic-Cigarette Flavoring Exposure on the Immature Lung.

Berkelhamer SK, Helman JM, Gugino SF, Leigh NJ, Lakshminrusimha S, Goniewicz ML.

Int J Environ Res Public Health. 2019 Sep 27;16(19). pii: E3635. doi: 10.3390/ijerph16193635.


Diaphragmatic Peritoneal Stripping Versus Full-Thickness Resection in CRS/HIPEC: Is There a Difference?

Sullivan BJ, Bekhor EY, Carpiniello M, Leigh NL, Pletcher ER, Solomon D, Magge DR, Sarpel U, Labow DM, Golas BJ.

Ann Surg Oncol. 2020 Jan;27(1):250-258. doi: 10.1245/s10434-019-07797-8. Epub 2019 Sep 9.


Correction to: Surveillance of Low-Grade Appendiceal Mucinous Neoplasms With Peritoneal Metastases After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Are 5 Years Enough? A Multisite Experience.

Solomon D, Bekhor E, Leigh N, Maniar YM, Totin L, Hofstedt M, Aycart SN, Carr J, Ballentine S, Magge DR, Golas BJ, Pai RK, Polydorides AD, Bartlett DL, Labow DM, Choudry HA, Sarpel U.

Ann Surg Oncol. 2019 Dec;26(Suppl 3):890. doi: 10.1245/s10434-019-07739-4.


Surveillance of Low-Grade Appendiceal Mucinous Neoplasms With Peritoneal Metastases After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Are 5 Years Enough? A Multisite Experience.

Solomon D, Bekhor E, Leigh N, Maniar YM, Totin L, Hofstedt M, Aycart SN, Carr J, Ballentine S, Magge DR, Golas BJ, Pai RK, Polydorides AD, Bartlett DL, Labow DM, Choudry HA, Sarpel U.

Ann Surg Oncol. 2020 Jan;27(1):147-153. doi: 10.1245/s10434-019-07678-0. Epub 2019 Aug 5. Erratum in: Ann Surg Oncol. 2019 Dec;26(Suppl 3):890.


Improved Survival with Experience: A 10-Year Learning Curve in Hyperthermic Intraperitoneal Chemotherapy and Cytoreductive Surgery.

Leigh NL, Solomon D, Feingold D, Magge DR, Golas BJ, Sarpel U, Labow DM.

Ann Surg Oncol. 2020 Jan;27(1):222-231. doi: 10.1245/s10434-019-07518-1. Epub 2019 Jun 20.


An exploration into "do-it-yourself" (DIY) e-liquid mixing: Users' motivations, practices and product laboratory analysis.

Cox S, Leigh NJ, Vanderbush TS, Choo E, Goniewicz ML, Dawkins L.

Addict Behav Rep. 2018 Dec 7;9:100151. doi: 10.1016/j.abrep.2018.100151. eCollection 2019 Jun.


Identification of flavouring chemicals and potential toxicants in e-cigarette products in Ontario, Canada.

Czoli CD, Goniewicz ML, Palumbo M, Leigh N, White CM, Hammond D.

Can J Public Health. 2019 Oct;110(5):542-550. doi: 10.17269/s41997-019-00208-1. Epub 2019 Apr 25.


Staging gallbladder cancer with lymphadenectomy: the practical application of new AHPBA and AJCC guidelines.

Leigh NL, Solomon D, Feingold D, Hiotis SP, Labow DM, Magge DR, Sarpel U, Golas BJ.

HPB (Oxford). 2019 Nov;21(11):1563-1569. doi: 10.1016/j.hpb.2019.03.372. Epub 2019 Apr 19.


Clinical evaluation and cost analysis of a Trioplex real-time PCR assay for the detection and differentiation of herpes simplex virus 1 and 2 in cutaneous and mucocutaneous lesions.

Navidad J, Pfotenhauer B, Leigh N, Maas E, Gradus S, Bhattacharyya S.

J Med Microbiol. 2019 May;68(5):748-754. doi: 10.1099/jmm.0.000971. Epub 2019 Apr 2.


Circadian Puffing Behavior and Topography Among E-cigarette Users.

Kosmider L, Jackson A, Leigh N, O'Connor R, Goniewicz ML.

Tob Regul Sci. 2018 Sep;4(5):41-49. doi: 10.18001/TRS.4.5.4.


The Role of Co-stimulatory/Co-inhibitory Signals in Graft-vs.-Host Disease.

Kumar S, Leigh ND, Cao X.

Front Immunol. 2018 Dec 21;9:3003. doi: 10.3389/fimmu.2018.03003. eCollection 2018. Review.


Transcriptomic landscape of the blastema niche in regenerating adult axolotl limbs at single-cell resolution.

Leigh ND, Dunlap GS, Johnson K, Mariano R, Oshiro R, Wong AY, Bryant DM, Miller BM, Ratner A, Chen A, Ye WW, Haas BJ, Whited JL.

Nat Commun. 2018 Dec 4;9(1):5153. doi: 10.1038/s41467-018-07604-0.


Corrigendum: Cystathionine β-Synthase Is Necessary for Axis Development in vivo.

Prabhudesai S, Koceja C, Dey A, Eisa-Beygi S, Leigh NR, Bhattacharya R, Mukherjee P, Ramchandran R.

Front Cell Dev Biol. 2018 Sep 27;6:121. doi: 10.3389/fcell.2018.00121. eCollection 2018.


Tobacco-specific nitrosamines (TSNA) in heated tobacco product IQOS.

Leigh NJ, Palumbo MN, Marino AM, O'Connor RJ, Goniewicz ML.

Tob Control. 2018 Nov;27(Suppl 1):s37-s38. doi: 10.1136/tobaccocontrol-2018-054318. Epub 2018 Sep 21. No abstract available.


Cytotoxic effects of heated tobacco products (HTP) on human bronchial epithelial cells.

Leigh NJ, Tran PL, O'Connor RJ, Goniewicz ML.

Tob Control. 2018 Nov;27(Suppl 1):s26-s29. doi: 10.1136/tobaccocontrol-2018-054317. Epub 2018 Sep 5.


Cystathionine β-Synthase Is Necessary for Axis Development in Vivo.

Prabhudesai S, Koceja C, Dey A, Eisa-Beygi S, Leigh NR, Bhattacharya R, Mukherjee P, Ramchandran R.

Front Cell Dev Biol. 2018 Feb 16;6:14. doi: 10.3389/fcell.2018.00014. eCollection 2018. Erratum in: Front Cell Dev Biol. 2018 Sep 27;6:121.


Identification of regenerative roadblocks via repeat deployment of limb regeneration in axolotls.

Bryant DM, Sousounis K, Payzin-Dogru D, Bryant S, Sandoval AGW, Martinez Fernandez J, Mariano R, Oshiro R, Wong AY, Leigh ND, Johnson K, Whited JL.

NPJ Regen Med. 2017 Nov 6;2:30. doi: 10.1038/s41536-017-0034-z. eCollection 2017.


Rare, Uncommon, and Unusual Complications After Pancreaticoduodenal Resection.

Lwin TM, Leigh N, Iskandar ME, Steele JG, Wayne MG, Cooperman AM.

Surg Clin North Am. 2018 Feb;98(1):87-94. doi: 10.1016/j.suc.2017.09.015. Review.


Host-Derived CD70 Suppresses Murine Graft-versus-Host Disease by Limiting Donor T Cell Expansion and Effector Function.

Leigh ND, O'Neill RE, Du W, Chen C, Qiu J, Ashwell JD, McCarthy PL, Chen GL, Cao X.

J Immunol. 2017 Jul 1;199(1):336-347. doi: 10.4049/jimmunol.1502181. Epub 2017 May 26.


Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.

Smith BN, Topp SD, Fallini C, Shibata H, Chen HJ, Troakes C, King A, Ticozzi N, Kenna KP, Soragia-Gkazi A, Miller JW, Sato A, Dias DM, Jeon M, Vance C, Wong CH, de Majo M, Kattuah W, Mitchell JC, Scotter EL, Parkin NW, Sapp PC, Nolan M, Nestor PJ, Simpson M, Weale M, Lek M, Baas F, Vianney de Jong JM, Ten Asbroek ALMA, Redondo AG, Esteban-Pérez J, Tiloca C, Verde F, Duga S, Leigh N, Pall H, Morrison KE, Al-Chalabi A, Shaw PJ, Kirby J, Turner MR, Talbot K, Hardiman O, Glass JD, De Belleroche J, Maki M, Moss SE, Miller C, Gellera C, Ratti A, Al-Sarraj S, Brown RH Jr, Silani V, Landers JE, Shaw CE.

Sci Transl Med. 2017 May 3;9(388). pii: eaad9157. doi: 10.1126/scitranslmed.aad9157.


A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors.

Bryant DM, Johnson K, DiTommaso T, Tickle T, Couger MB, Payzin-Dogru D, Lee TJ, Leigh ND, Kuo TH, Davis FG, Bateman J, Bryant S, Guzikowski AR, Tsai SL, Coyne S, Ye WW, Freeman RM Jr, Peshkin L, Tabin CJ, Regev A, Haas BJ, Whited JL.

Cell Rep. 2017 Jan 17;18(3):762-776. doi: 10.1016/j.celrep.2016.12.063.


Granzyme B Contributes to the Optimal Graft-Versus-Tumor Effect Mediated by Conventional CD4+ T Cells.

Du W, Leigh ND, Bian G, Alqassim E, O'Neill RE, Mei L, Qiu J, Liu H, McCarthy PL, Cao X.

J Immunol Res Ther. 2016;1(1):22-28. Epub 2016 Apr 30.


Interferon-Gamma Receptor Signaling Plays an Important Role in Restraining Murine Ovarian Tumor Progression.

Bian G, Leigh ND, Du W, Zhang L, Li L, Cao X.

J Immunol Res Ther. 2016;1(1):15-21. Epub 2016 Apr 28.


Flavourings significantly affect inhalation toxicity of aerosol generated from electronic nicotine delivery systems (ENDS).

Leigh NJ, Lawton RI, Hershberger PA, Goniewicz ML.

Tob Control. 2016 Nov;25(Suppl 2):ii81-ii87. doi: 10.1136/tobaccocontrol-2016-053205. Epub 2016 Sep 15.


Benzoxazinone-Mediated Triazine Degradation: A Proposed Reaction Mechanism.

Willett CD, Lerch RN, Lin CH, Goyne KW, Leigh ND, Roberts CA.

J Agric Food Chem. 2016 Jun 22;64(24):4858-65. doi: 10.1021/acs.jafc.6b01017. Epub 2016 Jun 7.


Dual use of electronic and tobacco cigarettes among adolescents: a cross-sectional study in Poland.

Goniewicz ML, Leigh NJ, Gawron M, Nadolska J, Balwicki L, McGuire C, Sobczak A.

Int J Public Health. 2016 Mar;61(2):189-97. doi: 10.1007/s00038-015-0756-x. Epub 2015 Oct 31.


Housing Temperature-Induced Stress Is Suppressing Murine Graft-versus-Host Disease through β2-Adrenergic Receptor Signaling.

Leigh ND, Kokolus KM, O'Neill RE, Du W, Eng JW, Qiu J, Chen GL, McCarthy PL, Farrar JD, Cao X, Repasky EA.

J Immunol. 2015 Nov 15;195(10):5045-54. doi: 10.4049/jimmunol.1500700. Epub 2015 Oct 12.


Cystathionine β-synthase regulates endothelial function via protein S-sulfhydration.

Saha S, Chakraborty PK, Xiong X, Dwivedi SK, Mustafi SB, Leigh NR, Ramchandran R, Mukherjee P, Bhattacharya R.

FASEB J. 2016 Jan;30(1):441-56. doi: 10.1096/fj.15-278648. Epub 2015 Sep 24.


Granzyme B-Mediated Activation-Induced Death of CD4+ T Cells Inhibits Murine Acute Graft-versus-Host Disease.

Du W, Leigh ND, Bian G, O'Neill RE, Mei L, Qiu J, Chen GL, Hahn T, Liu H, McCarthy PL, Cao X.

J Immunol. 2015 Nov 1;195(9):4514-23. doi: 10.4049/jimmunol.1500668. Epub 2015 Sep 21.


Stem Cell-Soluble Signals Enhance Multilumen Formation in SMG Cell Clusters.

Maruyama CL, Leigh NJ, Nelson JW, McCall AD, Mellas RE, Lei P, Andreadis ST, Baker OJ.

J Dent Res. 2015 Nov;94(11):1610-7. doi: 10.1177/0022034515600157. Epub 2015 Aug 18.


A simple method for isolation and purification of DIBOA-Glc from Tripsacum dactyloides.

Willett CD, Lerch RN, Goyne KW, Leigh ND, Lin CH, Roberts CA.

Nat Prod Commun. 2014 Sep;9(9):1283-6.


Defining immunological impact and therapeutic benefit of mild heating in a murine model of arthritis.

Lee CT, Kokolus KM, Leigh ND, Capitano M, Hylander BL, Repasky EA.

PLoS One. 2015 Mar 20;10(3):e0120327. doi: 10.1371/journal.pone.0120327. eCollection 2015.


Zonula occludens-1, occludin and E-cadherin expression and organization in salivary glands with Sjögren's syndrome.

Mellas RE, Leigh NJ, Nelson JW, McCall AD, Baker OJ.

J Histochem Cytochem. 2015 Jan;63(1):45-56. doi: 10.1369/0022155414555145. Epub 2014 Sep 23.


Isolation and identification of an allelopathic phenylethylamine in rice.

Le Thi H, Lin CH, Smeda RJ, Leigh ND, Wycoff WG, Fritschi FB.

Phytochemistry. 2014 Dec;108:109-21. doi: 10.1016/j.phytochem.2014.08.019. Epub 2014 Sep 8.


Three-dimensional cultures of mouse submandibular and parotid glands: a comparative study.

Leigh NJ, Nelson JW, Mellas RE, McCall AD, Baker OJ.

J Tissue Eng Regen Med. 2017 Mar;11(3):618-626. doi: 10.1002/term.1952. Epub 2014 Sep 4.


Effect of Gsk3 inhibitor CHIR99021 on aneuploidy levels in rat embryonic stem cells.

Bock AS, Leigh ND, Bryda EC.

In Vitro Cell Dev Biol Anim. 2014 Jun;50(6):572-9. doi: 10.1007/s11626-014-9734-5. Epub 2014 Feb 12.


A flagellin-derived toll-like receptor 5 agonist stimulates cytotoxic lymphocyte-mediated tumor immunity.

Leigh ND, Bian G, Ding X, Liu H, Aygun-Sunar S, Burdelya LG, Gudkov AV, Cao X.

PLoS One. 2014 Jan 14;9(1):e85587. doi: 10.1371/journal.pone.0085587. eCollection 2014.


Expression of resolvin D1 biosynthetic pathways in salivary epithelium.

Leigh NJ, Nelson JW, Mellas RE, Aguirre A, Baker OJ.

J Dent Res. 2014 Mar;93(3):300-5. doi: 10.1177/0022034513519108. Epub 2014 Jan 3.


ALX/FPR2 receptor for RvD1 is expressed and functional in salivary glands.

Nelson JW, Leigh NJ, Mellas RE, McCall AD, Aguirre A, Baker OJ.

Am J Physiol Cell Physiol. 2014 Jan 15;306(2):C178-85. doi: 10.1152/ajpcell.00284.2013. Epub 2013 Nov 20.


A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis.

Fogh I, Ratti A, Gellera C, Lin K, Tiloca C, Moskvina V, Corrado L, Sorarù G, Cereda C, Corti S, Gentilini D, Calini D, Castellotti B, Mazzini L, Querin G, Gagliardi S, Del Bo R, Conforti FL, Siciliano G, Inghilleri M, Saccà F, Bongioanni P, Penco S, Corbo M, Sorbi S, Filosto M, Ferlini A, Di Blasio AM, Signorini S, Shatunov A, Jones A, Shaw PJ, Morrison KE, Farmer AE, Van Damme P, Robberecht W, Chiò A, Traynor BJ, Sendtner M, Melki J, Meininger V, Hardiman O, Andersen PM, Leigh NP, Glass JD, Overste D, Diekstra FP, Veldink JH, van Es MA, Shaw CE, Weale ME, Lewis CM, Williams J, Brown RH, Landers JE, Ticozzi N, Ceroni M, Pegoraro E, Comi GP, D'Alfonso S, van den Berg LH, Taroni F, Al-Chalabi A, Powell J, Silani V; SLAGEN Consortium and Collaborators.

Hum Mol Genet. 2014 Apr 15;23(8):2220-31. doi: 10.1093/hmg/ddt587. Epub 2013 Nov 20.


No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis.

Goris A, van Setten J, Diekstra F, Ripke S, Patsopoulos NA, Sawcer SJ; International Multiple Sclerosis Genetics Consortium, van Es M; Australia and New Zealand MS Genetics Consortium, Andersen PM, Melki J, Meininger V, Hardiman O, Landers JE, Brown RH Jr, Shatunov A, Leigh N, Al-Chalabi A, Shaw CE, Traynor BJ, Chiò A, Restagno G, Mora G, Ophoff RA, Oksenberg JR, Van Damme P, Compston A, Robberecht W, Dubois B, van den Berg LH, De Jager PL, Veldink JH, de Bakker PI.

Hum Mol Genet. 2014 Apr 1;23(7):1916-22. doi: 10.1093/hmg/ddt574. Epub 2013 Nov 13.


Mmp17b is essential for proper neural crest cell migration in vivo.

Leigh NR, Schupp MO, Li K, Padmanabhan V, Gastonguay A, Wang L, Chun CZ, Wilkinson GA, Ramchandran R.

PLoS One. 2013 Oct 1;8(10):e76484. doi: 10.1371/journal.pone.0076484. eCollection 2013.


Identification of an atrazine-degrading benzoxazinoid in Eastern gamagrass (Tripsacum dactyloides).

Willett CD, Lerch RN, Lin CH, Goyne KW, Leigh ND, Roberts CA.

J Agric Food Chem. 2013 Aug 28;61(34):8026-33. doi: 10.1021/jf402271h. Epub 2013 Aug 15.


Growth factors polymerized within fibrin hydrogel promote amylase production in parotid cells.

McCall AD, Nelson JW, Leigh NJ, Duffey ME, Lei P, Andreadis ST, Baker OJ.

Tissue Eng Part A. 2013 Oct;19(19-20):2215-25. doi: 10.1089/ten.TEA.2012.0674. Epub 2013 May 25.


Understanding resolvin signaling pathways to improve oral health.

Keinan D, Leigh NJ, Nelson JW, De Oleo L, Baker OJ.

Int J Mol Sci. 2013 Mar 8;14(3):5501-18. doi: 10.3390/ijms14035501.

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