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Items: 1 to 50 of 260

1.

Stereoselective synthesis of a composite knot with nine crossings.

Zhang L, Stephens AJ, Nussbaumer AL, Lemonnier JF, Jurček P, Vitorica-Yrezabal IJ, Leigh DA.

Nat Chem. 2018 Sep 10. doi: 10.1038/s41557-018-0124-6. [Epub ahead of print]

PMID:
30202101
2.

A Six-Crossing Doubly Interlocked [2]Catenane with Twisted Rings, and a Molecular Granny Knot.

Danon JJ, Leigh DA, Pisano S, Valero A, Vitorica-Yrezabal IJ.

Angew Chem Int Ed Engl. 2018 Aug 28. doi: 10.1002/anie.201807135. [Epub ahead of print]

PMID:
30152565
3.

Comment on "Coordination-Driven Self-Assembly of a Molecular Knot Comprising Sixteen Crossings".

Leigh DA, Lemonnier JF, Woltering SL.

Angew Chem Int Ed Engl. 2018 Sep 17;57(38):12212-12214. doi: 10.1002/anie.201804904. Epub 2018 Aug 27.

PMID:
30152176
4.

Spontaneous Assembly of Rotaxanes from a Primary Amine, Crown Ether and Electrophile.

Fielden SDP, Leigh DA, McTernan CT, Pérez-Saavedra B, Vitorica-Yrezabal IJ.

J Am Chem Soc. 2018 May 16;140(19):6049-6052. doi: 10.1021/jacs.8b03394. Epub 2018 May 3.

PMID:
29717609
5.

Securing a Supramolecular Architecture by Tying a Stopper Knot.

Leigh DA, Pirvu L, Schaufelberger F, Tetlow DJ, Zhang L.

Angew Chem Int Ed Engl. 2018 Aug 13;57(33):10484-10488. doi: 10.1002/anie.201803871. Epub 2018 May 27.

6.

An artificial molecular machine that builds an asymmetric catalyst.

De Bo G, Gall MAY, Kuschel S, De Winter J, Gerbaux P, Leigh DA.

Nat Nanotechnol. 2018 May;13(5):381-385. doi: 10.1038/s41565-018-0105-3. Epub 2018 Apr 2.

PMID:
29610529
7.

Molecular Trefoil Knot from a Trimeric Circular Helicate.

Zhang L, August DP, Zhong J, Whitehead GFS, Vitorica-Yrezabal IJ, Leigh DA.

J Am Chem Soc. 2018 Apr 18;140(15):4982-4985. doi: 10.1021/jacs.8b00738. Epub 2018 Mar 20.

PMID:
29537836
8.

Molecular machines with bio-inspired mechanisms.

Zhang L, Marcos V, Leigh DA.

Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9397-9404. doi: 10.1073/pnas.1712788115. Epub 2018 Feb 26.

PMID:
29483259
9.

Transient two-dimensional vibrational spectroscopy of an operating molecular machine.

Panman MR, van Dijk CN, Huerta-Viga A, Sanders HJ, Bakker BH, Leigh DA, Brouwer AM, Buma WJ, Woutersen S.

Nat Commun. 2017 Dec 20;8(1):2206. doi: 10.1038/s41467-017-02278-6.

10.

A complementary pair of enantioselective switchable organocatalysts.

De Bo G, Leigh DA, McTernan CT, Wang S.

Chem Sci. 2017 Oct 1;8(10):7077-7081. doi: 10.1039/c7sc02462b. Epub 2017 Aug 23.

11.

Rotary and linear molecular motors driven by pulses of a chemical fuel.

Erbas-Cakmak S, Fielden SDP, Karaca U, Leigh DA, McTernan CT, Tetlow DJ, Wilson MR.

Science. 2017 Oct 20;358(6361):340-343. doi: 10.1126/science.aao1377.

PMID:
29051374
12.

Stereodivergent synthesis with a programmable molecular machine.

Kassem S, Lee ATL, Leigh DA, Marcos V, Palmer LI, Pisano S.

Nature. 2017 Sep 20;549(7672):374-378. doi: 10.1038/nature23677.

PMID:
28933436
13.

Preferential selection and transfer of euploid noncarrier embryos in preimplantation genetic diagnosis cycles for reciprocal translocations.

Wang L, Shen J, Cram DS, Ma M, Wang H, Zhang W, Fan J, Gao Z, Zhang L, Li Z, Xu M, Leigh DA, Trounson AO, Liu J, Yao Y.

Fertil Steril. 2017 Oct;108(4):620-627.e4. doi: 10.1016/j.fertnstert.2017.07.010. Epub 2017 Aug 30.

PMID:
28863935
14.

Enzyme-Mediated Directional Transport of a Small-Molecule Walker With Chemically Identical Feet.

Martin CJ, Lee ATL, Adams RW, Leigh DA.

J Am Chem Soc. 2017 Aug 30;139(34):11998-12002. doi: 10.1021/jacs.7b06503. Epub 2017 Aug 15.

15.

Sequence-Specific β-Peptide Synthesis by a Rotaxane-Based Molecular Machine.

De Bo G, Gall MAY, Kitching MO, Kuschel S, Leigh DA, Tetlow DJ, Ward JW.

J Am Chem Soc. 2017 Aug 9;139(31):10875-10879. doi: 10.1021/jacs.7b05850. Epub 2017 Jul 26.

PMID:
28723130
16.

Switching between Anion-Binding Catalysis and Aminocatalysis with a Rotaxane Dual-Function Catalyst.

Eichstaedt K, Jaramillo-Garcia J, Leigh DA, Marcos V, Pisano S, Singleton TA.

J Am Chem Soc. 2017 Jul 12;139(27):9376-9381. doi: 10.1021/jacs.7b04955. Epub 2017 Jul 3.

PMID:
28627882
17.

[2]Rotaxane Formation by Transition State Stabilization.

De Bo G, Dolphijn G, McTernan CT, Leigh DA.

J Am Chem Soc. 2017 Jun 28;139(25):8455-8457. doi: 10.1021/jacs.7b05640. Epub 2017 Jun 19.

PMID:
28621939
18.

Molecular Knots.

Fielden SDP, Leigh DA, Woltering SL.

Angew Chem Int Ed Engl. 2017 Sep 4;56(37):11166-11194. doi: 10.1002/anie.201702531. Epub 2017 Aug 16. Review.

19.

Pyridyl-Acyl Hydrazone Rotaxanes and Molecular Shuttles.

Leigh DA, Marcos V, Nalbantoglu T, Vitorica-Yrezabal IJ, Yasar FT, Zhu X.

J Am Chem Soc. 2017 May 24;139(20):7104-7109. doi: 10.1021/jacs.7b03307. Epub 2017 May 11.

PMID:
28471662
20.

Artificial molecular motors.

Kassem S, van Leeuwen T, Lubbe AS, Wilson MR, Feringa BL, Leigh DA.

Chem Soc Rev. 2017 May 9;46(9):2592-2621. doi: 10.1039/c7cs00245a. Review.

PMID:
28426052
21.

Braiding a molecular knot with eight crossings.

Danon JJ, Krüger A, Leigh DA, Lemonnier JF, Stephens AJ, Vitorica-Yrezabal IJ, Woltering SL.

Science. 2017 Jan 13;355(6321):159-162. doi: 10.1126/science.aal1619.

PMID:
28082585
22.

Genesis of the Nanomachines: The 2016 Nobel Prize in Chemistry.

Leigh DA.

Angew Chem Int Ed Engl. 2016 Nov 14;55(47):14506-14508. doi: 10.1002/anie.201609841. Epub 2016 Oct 20.

PMID:
27763727
23.

Tying a Molecular Overhand Knot of Single Handedness and Asymmetric Catalysis with the Corresponding Pseudo-D3-Symmetric Trefoil Knot.

Gil-Ramírez G, Hoekman S, Kitching MO, Leigh DA, Vitorica-Yrezabal IJ, Zhang G.

J Am Chem Soc. 2016 Oct 12;138(40):13159-13162. Epub 2016 Sep 29.

24.

Triply Threaded [4]Rotaxanes.

Danon JJ, Leigh DA, McGonigal PR, Ward JW, Wu J.

J Am Chem Soc. 2016 Sep 28;138(38):12643-7. doi: 10.1021/jacs.6b07733. Epub 2016 Sep 13.

PMID:
27570875
25.

Allosteric initiation and regulation of catalysis with a molecular knot.

Marcos V, Stephens AJ, Jaramillo-Garcia J, Nussbaumer AL, Woltering SL, Valero A, Lemonnier JF, Vitorica-Yrezabal IJ, Leigh DA.

Science. 2016 Jun 24;352(6293):1555-9. doi: 10.1126/science.aaf3673.

PMID:
27339983
26.

An autonomous chemically fuelled small-molecule motor.

Wilson MR, Solà J, Carlone A, Goldup SM, Lebrasseur N, Leigh DA.

Nature. 2016 Jun 9;534(7606):235-40. doi: 10.1038/nature18013.

PMID:
27279219
27.

Successive Translocation of the Rings in a [3]Rotaxane.

Jagesar DC, Wiering PG, Kay ER, Leigh DA, Brouwer AM.

Chemphyschem. 2016 Jun 17;17(12):1902-12. doi: 10.1002/cphc.201501162. Epub 2016 Mar 29.

PMID:
26918870
28.

Asymmetric Catalysis with a Mechanically Point-Chiral Rotaxane.

Cakmak Y, Erbas-Cakmak S, Leigh DA.

J Am Chem Soc. 2016 Feb 17;138(6):1749-51. doi: 10.1021/jacs.6b00303. Epub 2016 Feb 4.

29.

Pick-up, transport and release of a molecular cargo using a small-molecule robotic arm.

Kassem S, Lee AT, Leigh DA, Markevicius A, Solà J.

Nat Chem. 2016 Feb;8(2):138-43. doi: 10.1038/nchem.2410. Epub 2015 Dec 21.

PMID:
26791896
30.

Artificial Molecular Machines.

Erbas-Cakmak S, Leigh DA, McTernan CT, Nussbaumer AL.

Chem Rev. 2015 Sep 23;115(18):10081-206. doi: 10.1021/acs.chemrev.5b00146. Epub 2015 Sep 8. Review. No abstract available.

31.

Rise of the Molecular Machines.

Kay ER, Leigh DA.

Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10080-8. doi: 10.1002/anie.201503375. Epub 2015 Jul 27. No abstract available.

32.

Lanthanide Template Synthesis of Trefoil Knots of Single Handedness.

Zhang G, Gil-Ramírez G, Markevicius A, Browne C, Vitorica-Yrezabal IJ, Leigh DA.

J Am Chem Soc. 2015 Aug 19;137(32):10437-42. doi: 10.1021/jacs.5b07069. Epub 2015 Aug 4.

PMID:
26214819
33.

Strong and Selective Anion Binding within the Central Cavity of Molecular Knots and Links.

Ayme JF, Beves JE, Campbell CJ, Gil-Ramírez G, Leigh DA, Stephens AJ.

J Am Chem Soc. 2015 Aug 12;137(31):9812-5. doi: 10.1021/jacs.5b06340. Epub 2015 Jul 13.

34.

Goldberg Active Template Synthesis of a [2]Rotaxane Ligand for Asymmetric Transition-Metal Catalysis.

Hoekman S, Kitching MO, Leigh DA, Papmeyer M, Roke D.

J Am Chem Soc. 2015 Jun 24;137(24):7656-9. doi: 10.1021/jacs.5b04726. Epub 2015 Jun 16.

PMID:
26061430
35.

Artificial switchable catalysts.

Blanco V, Leigh DA, Marcos V.

Chem Soc Rev. 2015 Aug 7;44(15):5341-70. doi: 10.1039/c5cs00096c. Epub 2015 May 12. Review.

PMID:
25962337
36.

A Solomon link through an interwoven molecular grid.

Beves JE, Danon JJ, Leigh DA, Lemonnier JF, Vitorica-Yrezabal IJ.

Angew Chem Int Ed Engl. 2015 Jun 22;54(26):7555-9. doi: 10.1002/anie.201502095. Epub 2015 May 8.

37.

Catenanes: fifty years of molecular links.

Gil-Ramírez G, Leigh DA, Stephens AJ.

Angew Chem Int Ed Engl. 2015 May 18;54(21):6110-50. doi: 10.1002/anie.201411619. Epub 2015 May 7.

38.

A mechanically interlocked molecular system programmed for the delivery of an anticancer drug.

Barat R, Legigan T, Tranoy-Opalinski I, Renoux B, Péraudeau E, Clarhaut J, Poinot P, Fernandes AE, Aucagne V, Leigh DA, Papot S.

Chem Sci. 2015 Apr 1;6(4):2608-2613. doi: 10.1039/c5sc00648a. Epub 2015 Feb 25.

39.

Selecting reactions and reactants using a switchable rotaxane organocatalyst with two different active sites.

Beswick J, Blanco V, De Bo G, Leigh DA, Lewandowska U, Lewandowski B, Mishiro K.

Chem Sci. 2015 Jan 1;6(1):140-143. doi: 10.1039/c4sc03279a. Epub 2014 Nov 13.

40.

A Star of David catenane.

Leigh DA, Pritchard RG, Stephens AJ.

Nat Chem. 2014 Nov;6(11):978-82. doi: 10.1038/nchem.2056. Epub 2014 Sep 21.

PMID:
25343602
41.

A simple and highly effective ligand system for the copper(I)-mediated assembly of rotaxanes.

Campbell CJ, Leigh DA, Vitorica-Yrezabal IJ, Woltering SL.

Angew Chem Int Ed Engl. 2014 Dec 8;53(50):13771-4. doi: 10.1002/anie.201407817. Epub 2014 Oct 14.

42.

Exploring the activation modes of a rotaxane-based switchable organocatalyst.

Blanco V, Leigh DA, Lewandowska U, Lewandowski B, Marcos V.

J Am Chem Soc. 2014 Nov 5;136(44):15775-80. doi: 10.1021/ja509236u. Epub 2014 Oct 21.

43.

Lanthanide template synthesis of a molecular trefoil knot.

Ayme JF, Gil-Ramírez G, Leigh DA, Lemonnier JF, Markevicius A, Muryn CA, Zhang G.

J Am Chem Soc. 2014 Sep 24;136(38):13142-5. doi: 10.1021/ja506886p. Epub 2014 Sep 10.

PMID:
25198065
44.

The self-sorting behavior of circular helicates and molecular knots and links.

Ayme JF, Beves JE, Campbell CJ, Leigh DA.

Angew Chem Int Ed Engl. 2014 Jul 21;53(30):7823-7. doi: 10.1002/anie.201404270. Epub 2014 Jun 4.

45.

Synthetic molecular walkers.

Leigh DA, Lewandowska U, Lewandowski B, Wilson MR.

Top Curr Chem. 2014;354:111-38. doi: 10.1007/128_2014_546. Review.

PMID:
24770565
46.

Efficient assembly of threaded molecular machines for sequence-specific synthesis.

De Bo G, Kuschel S, Leigh DA, Lewandowski B, Papmeyer M, Ward JW.

J Am Chem Soc. 2014 Apr 16;136(15):5811-4. doi: 10.1021/ja5022415. Epub 2014 Apr 7.

PMID:
24678971
47.

A switchable [2]rotaxane asymmetric organocatalyst that utilizes an acyclic chiral secondary amine.

Blanco V, Leigh DA, Marcos V, Morales-Serna JA, Nussbaumer AL.

J Am Chem Soc. 2014 Apr 2;136(13):4905-8. doi: 10.1021/ja501561c. Epub 2014 Mar 24.

PMID:
24649824
48.

Toward metal complexes that can directionally walk along tracks: controlled stepping of a molecular biped with a palladium(II) foot.

Beves JE, Blanco V, Blight BA, Carrillo R, D'Souza DM, Howgego D, Leigh DA, Slawin AM, Symes MD.

J Am Chem Soc. 2014 Feb 5;136(5):2094-100. doi: 10.1021/ja4123973. Epub 2014 Jan 22.

PMID:
24446768
49.

Identification of a jumping translocation following pre-implantation genetic diagnosis.

Carey L, Traversa MV, Wright DC, McArthur SJ, Leigh DA.

Am J Med Genet A. 2014 Jan;164A(1):279-81. doi: 10.1002/ajmg.a.36214. Epub 2013 Nov 20. No abstract available.

PMID:
24259372
50.

Water lubricates hydrogen-bonded molecular machines.

Panman MR, Bakker BH, den Uyl D, Kay ER, Leigh DA, Buma WJ, Brouwer AM, Geenevasen JA, Woutersen S.

Nat Chem. 2013 Nov;5(11):929-34. doi: 10.1038/nchem.1744. Epub 2013 Sep 1.

PMID:
24153370

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