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Items: 1 to 50 of 95

1.

Mucosal-associated invariant T cells and disease.

Toubal A, Nel I, Lotersztajn S, Lehuen A.

Nat Rev Immunol. 2019 Jul 15. doi: 10.1038/s41577-019-0191-y. [Epub ahead of print] Review.

PMID:
31308521
2.

[Mucosal-associated invariant T cells].

Rouxel O, Lehuen A.

Med Sci (Paris). 2018 Jun-Jul;34(6-7):518-522. doi: 10.1051/medsci/20183406008. Epub 2018 Jul 31. French. No abstract available.

3.

Mucosal-associated invariant T (MAIT) cells are depleted and prone to apoptosis in cardiometabolic disorders.

Touch S, Assmann KE, Aron-Wisnewsky J, Marquet F, Rouault C, Fradet M, Mosbah H, Consortium M, Isnard R, Helft G, Lehuen A, Poitou C, Clément K, André S; MetaCardis Consortium.

FASEB J. 2018 Apr 27:fj201800052RR. doi: 10.1096/fj.201800052RR. [Epub ahead of print]

PMID:
29957059
4.

Author Correction: Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes.

Rouxel O, DaSilva J, Beaudoin L, Nel I, Tard C, Cagninacci L, Kiaf B, Oshima M, Diedisheim M, Salou M, Corbett A, Rossjohn J, McCluskey J, Scharfmann R, Battaglia M, Polak M, Lantz O, Beltrand J, Lehuen A.

Nat Immunol. 2018 Sep;19(9):1035. doi: 10.1038/s41590-017-0023-9.

PMID:
29880894
5.

Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver.

Hegde P, Weiss E, Paradis V, Wan J, Mabire M, Sukriti S, Rautou PE, Albuquerque M, Picq O, Gupta AC, Ferrere G, Gilgenkrantz H, Kiaf B, Toubal A, Beaudoin L, Lettéron P, Moreau R, Lehuen A, Lotersztajn S.

Nat Commun. 2018 Jun 1;9(1):2146. doi: 10.1038/s41467-018-04450-y.

6.

Mucosal-associated invariant T cells in autoimmune and immune-mediated diseases.

Rouxel O, Lehuen A.

Immunol Cell Biol. 2018 Jul;96(6):618-629. doi: 10.1111/imcb.12011. Epub 2018 Mar 2. Review.

PMID:
29405379
7.

Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes.

Rouxel O, Da Silva J, Beaudoin L, Nel I, Tard C, Cagninacci L, Kiaf B, Oshima M, Diedisheim M, Salou M, Corbett A, Rossjohn J, McCluskey J, Scharfmann R, Battaglia M, Polak M, Lantz O, Beltrand J, Lehuen A.

Nat Immunol. 2017 Dec;18(12):1321-1331. doi: 10.1038/ni.3854. Epub 2017 Oct 9. Erratum in: Nat Immunol. 2018 Jun 7;:.

8.

Intestinal invalidation of the glucose transporter GLUT2 delays tissue distribution of glucose and reveals an unexpected role in gut homeostasis.

Schmitt CC, Aranias T, Viel T, Chateau D, Le Gall M, Waligora-Dupriet AJ, Melchior C, Rouxel O, Kapel N, Gourcerol G, Tavitian B, Lehuen A, Brot-Laroche E, Leturque A, Serradas P, Grosfeld A.

Mol Metab. 2016 Nov 4;6(1):61-72. doi: 10.1016/j.molmet.2016.10.008. eCollection 2017 Jan.

9.

IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans.

Alzaid F, Lagadec F, Albuquerque M, Ballaire R, Orliaguet L, Hainault I, Blugeon C, Lemoine S, Lehuen A, Saliba DG, Udalova IA, Paradis V, Foufelle F, Venteclef N.

JCI Insight. 2016 Dec 8;1(20):e88689. doi: 10.1172/jci.insight.88689.

10.

Defective Invariant Natural Killer T-Cell Suppression in Patients With Type 1 Diabetes.

Nel I, Lehuen A.

Diabetes. 2016 Aug;65(8):2121-3. doi: 10.2337/dbi16-0021. No abstract available.

11.

Ablation of interaction between IL-33 and ST2+ regulatory T cells increases immune cell-mediated hepatitis and activated NK cell liver infiltration.

Noel G, Arshad MI, Filliol A, Genet V, Rauch M, Lucas-Clerc C, Lehuen A, Girard JP, Piquet-Pellorce C, Samson M.

Am J Physiol Gastrointest Liver Physiol. 2016 Aug 1;311(2):G313-23. doi: 10.1152/ajpgi.00097.2016. Epub 2016 Jun 23.

12.

SLAM-associated protein favors the development of iNKT2 over iNKT17 cells.

Michel ML, Lenoir C, Massot B, Diem S, Pasquier B, Sawa S, Rignault-Bricard R, Lehuen A, Eberl G, Veillette A, Leite-de-Moraes M, Latour S.

Eur J Immunol. 2016 Sep;46(9):2162-74. doi: 10.1002/eji.201646313. Epub 2016 Jul 22.

13.

Regulatory role of natural killer T cells in diabetes.

Tard C, Rouxel O, Lehuen A.

Biomed J. 2015 Dec;38(6):484-95. doi: 10.1016/j.bj.2015.04.001. Epub 2016 Mar 10. Review.

14.

Lights on MAIT cells, a new immune player in liver diseases.

Toubal A, Lehuen A.

J Hepatol. 2016 May;64(5):1008-1010. doi: 10.1016/j.jhep.2016.02.003. Epub 2016 Feb 8. No abstract available.

PMID:
26867492
15.

[Mucosal-associated invariant T cells in obesity and type 2 diabetes].

Magalhaes I, Lehuen A.

Med Sci (Paris). 2015 Aug-Sep;31(8-9):717-9. doi: 10.1051/medsci/20153108005. Epub 2015 Sep 4. French. No abstract available.

16.

iNKT and MAIT Cell Alterations in Diabetes.

Magalhaes I, Kiaf B, Lehuen A.

Front Immunol. 2015 Jul 2;6:341. doi: 10.3389/fimmu.2015.00341. eCollection 2015. Review.

17.

Regulatory Role of Natural Killer T Cells in Diabetes.

Tard C, Rouxel O, Lehuen A.

Biomed J. 2015 Jun 12. doi: 10.4103/2319-4170.158622. [Epub ahead of print]

18.

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients.

Magalhaes I, Pingris K, Poitou C, Bessoles S, Venteclef N, Kiaf B, Beaudoin L, Da Silva J, Allatif O, Rossjohn J, Kjer-Nielsen L, McCluskey J, Ledoux S, Genser L, Torcivia A, Soudais C, Lantz O, Boitard C, Aron-Wisnewsky J, Larger E, Clément K, Lehuen A.

J Clin Invest. 2015 Apr;125(4):1752-62. doi: 10.1172/JCI78941. Epub 2015 Mar 9.

19.

A double-edged sword against type 1 diabetes.

Lehuen A.

N Engl J Med. 2015 Feb 19;372(8):778-80. doi: 10.1056/NEJMcibr1414708. No abstract available.

PMID:
25693020
20.

IgA, IgA receptors, and their anti-inflammatory properties.

Mkaddem SB, Christou I, Rossato E, Berthelot L, Lehuen A, Monteiro RC.

Curr Top Microbiol Immunol. 2014;382:221-35. doi: 10.1007/978-3-319-07911-0_10. Review.

PMID:
25116102
21.
22.

Administration of sulfatide to ameliorate type I diabetes in non-obese diabetic mice.

Rhost S, Lofbom L, Mansson J-, Lehuen A, Blomqvist M, Cardell SL.

Scand J Immunol. 2014 Apr;79(4):260-6.

PMID:
24795987
23.

Invariant NKT cell development: focus on NOD mice.

Ghazarian L, Simoni Y, Magalhaes I, Lehuen A.

Curr Opin Immunol. 2014 Apr;27:83-8. doi: 10.1016/j.coi.2014.02.004. Epub 2014 Mar 13. Review.

PMID:
24637104
24.

Invariant NKT cells regulate the CD8 T cell response during Theiler's virus infection.

Mars LT, Mas M, Beaudoin L, Bauer J, Leite-de-Moraes M, Lehuen A, Bureau JF, Liblau RS.

PLoS One. 2014 Jan 30;9(1):e87717. doi: 10.1371/journal.pone.0087717. eCollection 2014.

25.

Plasmacytoid dendritic cells license regulatory T cells, upon iNKT-cell stimulation, to prevent autoimmune diabetes.

Beaudoin L, Diana J, Ghazarian L, Simoni Y, Boitard C, Lehuen A.

Eur J Immunol. 2014 May;44(5):1454-66. doi: 10.1002/eji.201343910. Epub 2014 Feb 27.

26.

Organ-specific and systemic autoimmune diseases.

Lehuen A, Marshak-Rothstein A.

Curr Opin Immunol. 2013 Dec;25(6):667-9. doi: 10.1016/j.coi.2013.10.014. Epub 2013 Nov 16. No abstract available.

PMID:
24246387
27.

[Regulatory role of NKT cells in the prevention of type 1 diabetes].

Ghazarian L, Simoni Y, Pingris K, Beaudoin L, Lehuen A.

Med Sci (Paris). 2013 Aug-Sep;29(8-9):722-8. doi: 10.1051/medsci/2013298010. Epub 2013 Sep 5. Review. French.

28.

Secretory IgA induces tolerogenic dendritic cells through SIGNR1 dampening autoimmunity in mice.

Diana J, Moura IC, Vaugier C, Gestin A, Tissandie E, Beaudoin L, Corthésy B, Hocini H, Lehuen A, Monteiro RC.

J Immunol. 2013 Sep 1;191(5):2335-43. doi: 10.4049/jimmunol.1300864. Epub 2013 Aug 7.

29.

Protection against type 1 diabetes upon Coxsackievirus B4 infection and iNKT-cell stimulation: role of suppressive macrophages.

Ghazarian L, Diana J, Beaudoin L, Larsson PG, Puri RK, van Rooijen N, Flodström-Tullberg M, Lehuen A.

Diabetes. 2013 Nov;62(11):3785-96. doi: 10.2337/db12-0958. Epub 2013 Jul 26.

30.

Mast cell chymase protects against renal fibrosis in murine unilateral ureteral obstruction.

Beghdadi W, Madjene LC, Claver J, Pejler G, Beaudoin L, Lehuen A, Daugas E, Blank U.

Kidney Int. 2013 Aug;84(2):317-26. doi: 10.1038/ki.2013.98. Epub 2013 Mar 20.

31.

Functional education of invariant NKT cells by dendritic cell tuning of SHP-1.

Napolitano A, Pittoni P, Beaudoin L, Lehuen A, Voehringer D, MacDonald HR, Dellabona P, Casorati G.

J Immunol. 2013 Apr 1;190(7):3299-308. doi: 10.4049/jimmunol.1203466. Epub 2013 Feb 20.

32.

Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes.

Diana J, Simoni Y, Furio L, Beaudoin L, Agerberth B, Barrat F, Lehuen A.

Nat Med. 2013 Jan;19(1):65-73. doi: 10.1038/nm.3042. Epub 2012 Dec 16.

PMID:
23242473
33.

Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: are we close to reality?

Simoni Y, Diana J, Ghazarian L, Beaudoin L, Lehuen A.

Clin Exp Immunol. 2013 Jan;171(1):8-19. doi: 10.1111/j.1365-2249.2012.04625.x. Review.

34.

TRAIL but not FasL and TNFα, regulates IL-33 expression in murine hepatocytes during acute hepatitis.

Arshad MI, Piquet-Pellorce C, L'Helgoualc'h A, Rauch M, Patrat-Delon S, Ezan F, Lucas-Clerc C, Nabti S, Lehuen A, Cubero FJ, Girard JP, Trautwein C, Samson M.

Hepatology. 2012 Dec;56(6):2353-62. doi: 10.1002/hep.25893. Epub 2012 Sep 24.

PMID:
22961755
35.

Globosides but not isoglobosides can impact the development of invariant NKT cells and their interaction with dendritic cells.

Porubsky S, Speak AO, Salio M, Jennemann R, Bonrouhi M, Zafarulla R, Singh Y, Dyson J, Luckow B, Lehuen A, Malle E, Müthing J, Platt FM, Cerundolo V, Gröne HJ.

J Immunol. 2012 Sep 15;189(6):3007-17. doi: 10.4049/jimmunol.1201483. Epub 2012 Aug 8.

36.

Prevention or acceleration of type 1 diabetes by viruses.

Ghazarian L, Diana J, Simoni Y, Beaudoin L, Lehuen A.

Cell Mol Life Sci. 2013 Jan;70(2):239-55. doi: 10.1007/s00018-012-1042-1. Epub 2012 Jul 6. Review. Erratum in: Cell Mol Life Sci. 2013 Jan;70(2):257.

PMID:
22766971
37.

CD4(+) type II NKT cells mediate ICOS and programmed death-1-dependent regulation of type 1 diabetes.

Kadri N, Korpos E, Gupta S, Briet C, Löfbom L, Yagita H, Lehuen A, Boitard C, Holmberg D, Sorokin L, Cardell SL.

J Immunol. 2012 Apr 1;188(7):3138-49. doi: 10.4049/jimmunol.1101390. Epub 2012 Feb 27.

38.

Innate iNKT cell help to B cells: fast but does not last.

Lehuen A, Fazilleau N.

Nat Immunol. 2011 Dec 16;13(1):11-3. doi: 10.1038/ni.2186. No abstract available.

PMID:
22179271
39.

NOD mice contain an elevated frequency of iNKT17 cells that exacerbate diabetes.

Simoni Y, Gautron AS, Beaudoin L, Bui LC, Michel ML, Coumoul X, Eberl G, Leite-de-Moraes M, Lehuen A.

Eur J Immunol. 2011 Dec;41(12):3574-85. doi: 10.1002/eji.201141751. Epub 2011 Nov 10.

40.

Innate immunity in type 1 diabetes.

Diana J, Gahzarian L, Simoni Y, Lehuen A.

Discov Med. 2011 Jun;11(61):513-20. Review.

41.

Low numbers and altered phenotype of invariant natural killer T cells in recurrent varicella zoster virus infection.

Novakova L, Lehuen A, Novak J.

Cell Immunol. 2011;269(2):78-81. doi: 10.1016/j.cellimm.2011.04.008. Epub 2011 Apr 23.

PMID:
21570064
42.

Viral infection prevents diabetes by inducing regulatory T cells through NKT cell-plasmacytoid dendritic cell interplay.

Diana J, Brezar V, Beaudoin L, Dalod M, Mellor A, Tafuri A, von Herrath M, Boitard C, Mallone R, Lehuen A.

J Exp Med. 2011 Apr 11;208(4):729-45. doi: 10.1084/jem.20101692. Epub 2011 Mar 28.

43.

A natural protective function of invariant NKT cells in a mouse model of innate-cell-driven lung inflammation.

Bourgeois EA, Levescot A, Diem S, Chauvineau A, Bergès H, Milpied P, Lehuen A, Damotte D, Gombert JM, Schneider E, Girard JP, Gourdy P, Herbelin A.

Eur J Immunol. 2011 Feb;41(2):299-305. doi: 10.1002/eji.201040647. Epub 2011 Jan 11.

44.

Mechanism of regulation of autoimmunity by iNKT cells.

Novak J, Lehuen A.

Cytokine. 2011 Mar;53(3):263-70. doi: 10.1016/j.cyto.2010.11.001. Epub 2010 Dec 23. Review.

PMID:
21185200
45.

NKT and tolerance.

Diana J, Beaudoin L, Gautron AS, Lehuen A.

Methods Mol Biol. 2011;677:193-206. doi: 10.1007/978-1-60761-869-0_14.

PMID:
20941612
46.

Invariant NKT cells in adrenoleukodystrophy patients and mice.

Gautron AS, Giquel B, Beaudoin L, Autrusseau E, Speak A, Platt F, Kemp S, Pujol A, Aubourg P, Lehuen A.

J Neuroimmunol. 2010 Dec 15;229(1-2):204-11. doi: 10.1016/j.jneuroim.2010.09.003.

PMID:
20920830
47.

Immune cell crosstalk in type 1 diabetes.

Lehuen A, Diana J, Zaccone P, Cooke A.

Nat Rev Immunol. 2010 Jul;10(7):501-13. doi: 10.1038/nri2787. Review.

PMID:
20577267
48.

NKT cells: friend or foe during viral infections?

Diana J, Lehuen A.

Eur J Immunol. 2009 Dec;39(12):3283-91. doi: 10.1002/eji.200939800. Review.

49.

NKT cell-plasmacytoid dendritic cell cooperation via OX40 controls viral infection in a tissue-specific manner.

Diana J, Griseri T, Lagaye S, Beaudoin L, Autrusseau E, Gautron AS, Tomkiewicz C, Herbelin A, Barouki R, von Herrath M, Dalod M, Lehuen A.

Immunity. 2009 Feb 20;30(2):289-99. doi: 10.1016/j.immuni.2008.12.017. Epub 2009 Feb 12.

50.

A Griscelli syndrome type 2 murine model of hemophagocytic lymphohistiocytosis (HLH).

Pachlopnik Schmid J, Ho CH, Diana J, Pivert G, Lehuen A, Geissmann F, Fischer A, de Saint Basile G.

Eur J Immunol. 2008 Nov;38(11):3219-25. doi: 10.1002/eji.200838488.

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